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Extract from the Register of European Patents

EP About this file: EP1801231

EP1801231 - METHOD OF SCREENING BAFF SUPPRESSOR OR INHIBITOR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.10.2012
Database last updated on 19.10.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Kowa Co., Ltd.
6-29, Nishiki 3-chome Naka-ku
Nagoya-shi, Aichi 460-8625 / JP
For all designated states
Takeuchi, Tsutomu
2-20-7, Akatsutsumi Setagaya-ku
Tokyo 156-0044 / JP
For all designated states
Tsuzaka, Kensei
3-9-10-736 Takaidohigashi Suginami-ku
Tokyo 168-0072 / JP
For all designated states
Yoshimoto, Keiko
1-67-2-303, Yamatocho
Nakano-ku
Tokyo 165-0034 / JP
[N/P]
Former [2007/26]For all designated states
Kowa Co., Ltd.
6-29, Nishiki 3-chome Naka-ku
Nagoya-shi, Aichi 460-8625 / JP
For all designated states
Takeuchi, Tsutomu
2-20-7, Akatsutsumi Setagaya-ku
Tokyo 156-0044 / JP
For all designated states
Tsuzaka, Kensei
3-9-10-736 Takaidohigashi Suginami-ku
Tokyo 168-0072 / JP
For all designated states
Yoshimoto, Keiko
3-6-1-3-M, Hikaricho
Kokubunji-shi, Tokyo 185-0034 / JP
Inventor(s)01 / TAKEUCHI, Tsutomu
2-20-7, Akatsutsumi
Setagaya-ku
Tokyo 156-0044 / JP
02 / TSUZAKA, Kensei
3-9-10-736, Takaidohigashi
Suginami-ku
Tokyo 1680072 / JP
03 / YOSHIMOTO, Keiko
3-6-1-3-M, Hikaricho
Kokubunji-shi, Tokyo 185-0034 / JP
 [2011/48]
Former [2007/34]01 / TAKEUCHI, Tsutomu
2-20-7, Akatsutsumi, Setagaya-ku
Tokyo 156-0044 / JP
02 / TSUZAKA, Kensei
3-9-10-736, Takaidohigashi, Suginami-ku
Tokyo 1680072 / JP
03 / YOSHIMOTO, Keiko
3-6-1-3-M, Hikaricho
Kokubunji-shi, Tokyo 185-0034 / JP
Former [2007/26]01 / TAKEUCHI, Tsutomu
2-20-7, Akatsutsumi, Setagaya-ku
Tokyo 156-0044 / JP
02 / TZUSAKA, Kensei
3-9-10-736, Takaidohigashi, Suginami-ku
Tokyo 1680072 / JP
03 / YOSHIMOTO, Keiko
3-6-1-3-M, Hikaricho
Kokubunji-shi, Tokyo 185-0034 / JP
Representative(s)Hiebl, Inge Elisabeth
Kraus & Weisert
Patentanwälte PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
[N/P]
Former [2011/48]Hiebl, Inge Elisabeth
Kraus & Weisert Patent- und Rechtsanwälte Thomas-Wimmer-Ring 15
80539 München / DE
Former [2007/26]Hiebl, Inge Elisabeth
Kraus & Weisert Patent- und Rechtsanwälte Thomas-Wimmer-Ring 15
80539 München / DE
Application number, filing date05783483.014.09.2005
[2007/26]
WO2005JP16888
Priority number, dateUS20040609826P15.09.2004         Original published format: US 609826 P
[2007/26]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2006030802
Date:23.03.2006
Language:EN
[2006/12]
Type: A1 Application with search report 
No.:EP1801231
Date:27.06.2007
Language:EN
The application published by WIPO in one of the EPO official languages on 23.03.2006 takes the place of the publication of the European patent application.
[2007/26]
Type: B1 Patent specification 
No.:EP1801231
Date:30.11.2011
Language:EN
[2011/48]
Search report(s)International search report - published on:JP23.03.2006
(Supplementary) European search report - dispatched on:EP23.04.2008
ClassificationIPC:C12Q1/02, C12Q1/68, A61K39/395, A61K31/341, A61P43/00
[2007/26]
CPC:
C07K16/2875 (EP,US); A61K31/341 (EP,US); A61P29/00 (EP);
A61P3/10 (EP); A61P37/02 (EP); A61P37/04 (EP);
A61P37/06 (EP); A61P43/00 (EP); G01N33/5008 (EP,US);
G01N33/5023 (EP,US); G01N33/505 (EP,US); G01N33/5052 (EP,US);
G01N33/6863 (EP,US); G01N2500/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2007/26]
TitleGerman:VERFAHREN ZUM SCREENING DES BAFF-SUPPRESSORS ODER -INHIBITORS[2007/26]
English:METHOD OF SCREENING BAFF SUPPRESSOR OR INHIBITOR[2007/26]
French:PROCÉDÉ DE RECHERCHE PAR SCRIBLAGE D'UN SUPPRESSEUR OU INHIBITEUR DU BAFF[2007/26]
Entry into regional phase30.03.2007Translation filed 
30.03.2007National basic fee paid 
30.03.2007Search fee paid 
30.03.2007Designation fee(s) paid 
30.03.2007Examination fee paid 
Examination procedure30.03.2007Examination requested  [2007/26]
25.06.2008Despatch of a communication from the examining division (Time limit: M06)
22.12.2008Reply to a communication from the examining division
03.11.2010Despatch of a communication from the examining division (Time limit: M04)
07.03.2011Reply to a communication from the examining division
01.08.2011Communication of intention to grant the patent
18.10.2011Fee for grant paid
18.10.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  25.06.2008
Opposition(s)31.08.2012No opposition filed within time limit [2012/45]
Fees paidRenewal fee
12.09.2007Renewal fee patent year 03
15.09.2008Renewal fee patent year 04
08.09.2009Renewal fee patent year 05
10.09.2010Renewal fee patent year 06
27.09.2011Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU14.09.2005
AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
FI30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
TR30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
IS30.03.2012
PT30.03.2012
[2014/34]
Former [2014/21]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
FI30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
TR30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
IS30.03.2012
PT30.03.2012
Former [2013/29]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
FI30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
IS30.03.2012
PT30.03.2012
Former [2013/22]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
ES11.03.2012
IS30.03.2012
PT30.03.2012
Former [2013/07]AT30.11.2011
BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/37]BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
PL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/36]BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
RO30.11.2011
SE30.11.2011
SI30.11.2011
SK30.11.2011
BG29.02.2012
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/35]BE30.11.2011
CY30.11.2011
CZ30.11.2011
DK30.11.2011
EE30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
BG29.02.2012
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/34]BE30.11.2011
CY30.11.2011
CZ30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/28]BE30.11.2011
CY30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/25]BE30.11.2011
LT30.11.2011
LV30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/24]LT30.11.2011
LV30.11.2011
NL30.11.2011
SE30.11.2011
SI30.11.2011
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/23]LT30.11.2011
NL30.11.2011
GR01.03.2012
IS30.03.2012
PT30.03.2012
Former [2012/21]LT30.11.2011
IS30.03.2012
Former [2012/20]LT30.11.2011
Documents cited:Search[X]  - MARIENFELD RALF ET AL, "Signal-specific and phosphorylation-dependent RelB degradation: A potential mechanism of NF-kappaB control", ONCOGENE, (20011206), vol. 20, no. 56, ISSN 0950-9232, pages 8142 - 8147, XP002475875 [X] 11-14 * p. 8142, col. 2, lines 13 - 20, fig. 1d and e, fig. 4b *

DOI:   http://dx.doi.org/10.1038/sj.onc.1204884
 [A]  - LAVIE FRÉDÉRIC ET AL, "Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjögren's syndrome.", THE JOURNAL OF PATHOLOGY APR 2004, (200404), vol. 202, no. 4, ISSN 0022-3417, pages 496 - 502, XP002475876 [A] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1002/path.1533
 [A]  - SCHNEIDER P ET AL, "BAFF, A NOVEL LIGAND OF THE TUMOR NECROSIS FACTOR FAMILY, STIMULATES B CELL GROWTH", JOURNAL OF EXPERIMENTAL MEDICINE, TOKYO, JP, (19990607), vol. 189, no. 11, ISSN 0022-1007, pages 1747 - 1756, XP000915409 [A] 1-14 * abstract, p. 1752, paragraph bridging cols. 1and 2 *

DOI:   http://dx.doi.org/10.1084/jem.189.11.1747
 [T]  - YOSHIMOTO KEIKO ET AL, "Aberrant expression of BAFF in T cells of systemic lupus erythematosus, which is recapitulated by a human T cell line, Loucy", INTERNATIONAL IMMUNOLOGY, (200607), vol. 18, no. 7, ISSN 0953-8178, pages 1189 - 1196, XP002475877 [T] 1-14

DOI:   http://dx.doi.org/10.1093/intimm/dxl053
International search[X]  - SHU H.B. ET AL, "TALL-1 is a novel member of the TNF family that is down regulated by mitogens", JOURNAL OF LEUKOCYTE BIOLOGY, (1999), vol. 65, no. 5, pages 680 - 683, XP000939092
 [Y]  - MOORE P.A. ET AL, "BLyS: Member of the Tumor Necrosis Factor Family and B Lymphocyte Stimulator", SCIENCE, (1999), vol. 285, no. 5425, pages 260 - 263, XP002142252

DOI:   http://dx.doi.org/10.1126/science.285.5425.260
 [Y]  - BEN-BASSAT H. ET AL, "Establishment of a human T-Acute Lymphoblastic leukemia Cell Line with a (16;20) Chromosome Translocation", CANCER GENET. CYTOGENET., (1990), vol. 49, no. 2, pages 241 - 248, XP002993867

DOI:   http://dx.doi.org/10.1016/0165-4608(90)90148-4
 [Y]  - HUARD B. ET AL, "BAFF production by antigen-presenting cells provides T cell co-stimulation", INT. IMMUNOL., (200403), vol. 16, no. 3, pages 467 - 475, XP002993868

DOI:   http://dx.doi.org/10.1093/intimm/dxh043
 [Y]  - KHARE S.D. ET AL, "Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice", PROC. NATL. ACAD. SCI. USA, (2000), vol. 97, no. 7, pages 3370 - 3375, XP002142253

DOI:   http://dx.doi.org/10.1073/pnas.050580697
 [A]  - WU D. ET AL, "Expression of THANK in human PBMC activated with different stimulator", XIBAO YU FENZI MIANYIXUE ZAZHI, (2001), vol. 17, no. 4, pages 304 - 306, XP008058996
by applicantWO9818921
    - MOORE ET AL., SCIENCE, (1999), vol. 285, pages 260 - 263
    - HUARD B. ET AL., INT. IMMUNOL., (200403), vol. 16, no. 3, pages 467 - 475
    - MARIENFELD R. ET AL., ONCOGENE, (20011206), vol. 20, no. 56, pages 8142 - 8147
    - YOSHIMOTO K. ET AL., INT. IMMUNOL., (200607), vol. 18, no. 7, pages 1189 - 1196
    - SHU H. B. ET AL., J. LEUCOCYTE BIOL., (1999), vol. 65, no. 5, pages 680 - 683
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.