blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP1937305

EP1937305 - IMMUNOGLOBULIN COMPRISING PREDOMINANTLY A MAN7GLCNAC2, MAN8GLCNAC2 GLYCOFORM [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  28.11.2008
Database last updated on 15.06.2024
Most recent event   Tooltip07.08.2009Change - representativepublished on 09.09.2009  [2009/37]
Applicant(s)For all designated states
GlycoFi, Inc.
21 Lafayette Street, Suite 200
Lebanon, NH 03766 / US
[N/P]
Former [2008/27]For all designated states
GlycoFi, Inc.
21 Lafayette Street, Suite 200 Lebanon
New Hampshire 03766 / US
Inventor(s)01 / GERNGROSS, Tillman
2 Parkway
Hanover, NH 03755 / US
02 / WILDT, Stefan
32 Parkhurst Street
Lebanon, NH 03766 / US
03 / LI, Huijuan
8 Barden Hill Road
Lebanon, NH 03766 / US
 [2008/27]
Representative(s)Buchan, Gavin MacNicol
Merck Sharp & Dohme Limited
European Patent Department
Hertford Road
Hoddesdon
Hertfordshire EN11 9BU / GB
[N/P]
Former [2009/37]Buchan, Gavin MacNicol
Merck Sharp & Dohme Limited European Patent Department Hertford Road Hoddesdon
Hertfordshire EN11 9BU / GB
Former [2008/27]Buchan, Gavin MacNicol
Merck & Co., Inc. Hertford Road
Hoddesdon, Herts. EN11 9BU / GB
Application number, filing date05786499.309.09.2005
[2008/27]
WO2005IB52964
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007029054
Date:15.03.2007
Language:EN
[2007/11]
Type: A1 Application with search report 
No.:EP1937305
Date:02.07.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 15.03.2007 takes the place of the publication of the European patent application.
[2008/27]
Search report(s)International search report - published on:US15.03.2007
(Supplementary) European search report - dispatched on:EP05.09.2008
ClassificationIPC:A61K39/395, C07K14/00
[2008/27]
CPC:
C07K16/2887 (EP,US); C07K16/00 (EP,US); C07K2317/24 (EP,US);
C07K2317/41 (EP,US); C07K2317/72 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/27]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:IMMUNGLOBULIN, DAS VORWIEGEND EINE MAN7GLCNAC2, MAN8GLCNAC2 GLYCOFORM ENTHÄLT[2008/27]
English:IMMUNOGLOBULIN COMPRISING PREDOMINANTLY A MAN7GLCNAC2, MAN8GLCNAC2 GLYCOFORM[2008/27]
French:IMMUNOGLOBULINE COMPRENANT UNE GLYCOFORME À PRÉDOMINANCE MAN7GLCNAC2 OU MAN8GLCNAC2[2008/27]
Entry into regional phase09.04.2008National basic fee paid 
09.04.2008Search fee paid 
09.04.2008Designation fee(s) paid 
09.04.2008Examination fee paid 
Examination procedure04.03.2008Amendment by applicant (claims and/or description)
09.04.2008Examination requested  [2008/27]
10.11.2008Despatch of a communication from the examining division (Time limit: M04)
19.11.2008Application withdrawn by applicant  [2009/01]
Fees paidRenewal fee
09.04.2008Renewal fee patent year 03
27.03.2008Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO0200879  (GLYCOFI INC [US]) [A] 1-14;
 [A]WO03056914  (GLYCOFI INC [US], et al) [A] 1-14;
 [X]  - KO KISUNG ET AL, "Function and glycosylation of plant-derived antiviral monoclonal antibody.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 24 JUN 2003, (20030624), vol. 100, no. 13, ISSN 0027-8424, pages 8013 - 8018, XP002996058 [X] 1-8,10-12,14 * abstract * * figure 3 * * page 8016, column L, paragraph L *

DOI:   http://dx.doi.org/10.1073/pnas.0832472100
 [X]  - TRIGUERO ADA ET AL, "Plant-derived mouse IgG monoclonal antibody fused to KDEL endoplasmic reticulum-retention signal is N-glycosylated homogeneously throughout the plant with mostly high-mannose-type N-glycans.", PLANT BIOTECHNOLOGY JOURNAL JUL 2005, (200507), vol. 3, no. 4, ISSN 1467-7652, pages 449 - 457, XP002492954 [X] 1-8,10-12,14 * table 2 * * abstract *

DOI:   http://dx.doi.org/10.1111/j.1467-7652.2005.00137.x
 [X]  - SRIRAMAN RAJAN ET AL, "Recombinant anti-hCG antibodies retained in the endoplasmic reticulum of transformed plants lack core-xylose and core-alpha(1,3)-fucose residues.", PLANT BIOTECHNOLOGY JOURNAL JUL 2004, (200407), vol. 2, no. 4, ISSN 1467-7652, pages 279 - 287, XP002492955 [X] 1-8,10-12,14 * figure 4 * * abstract *

DOI:   http://dx.doi.org/10.1111/j.1467-7652.2004.00078.x
 [X]  - ARNOLD JAMES N ET AL, "The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 1 DEC 2004, (20041201), vol. 173, no. 11, ISSN 0022-1767, pages 6831 - 6840, XP002492956 [X] 1,8,12,14 * table IV * * abstract *
 [X]  - ROTHMAN R J ET AL, "Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylation", MOLECULAR IMMUNOLOGY, ELMSFORD, NY, US, (19891201), vol. 26, no. 12, ISSN 0161-5890, pages 1113 - 1123, XP002435543 [X] 1-14 * figures 3,5 * * abstract *

DOI:   http://dx.doi.org/10.1016/0161-5890(89)90055-2
 [A]  - ELBEIN A D, "GLYCOSIDASE INHIBITORS: INHIBITORS OF N-LINKED OLIGOSACCHARIDE PROCESSING", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, BETHESDA, MD, (19910101), vol. 5, no. 5, ISSN 0892-6638, pages 3055 - 3063, XP001194418 [A] 1-14
 [A]  - UMANA P ET AL, "ENGINEERED GLYCOFORMS OF AN ANTINEUROBLASTOMA IGG1 WITH OPTIMIZED ANTIBODY-DEPENDENT CELLULAR CYTOTOXIC ACTIVITY", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (19990201), vol. 17, ISSN 1087-0156, pages 176 - 180, XP002921620 [A] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1038/6179
 [A]  - JEFFERIS R ET AL, "IGG-FC-MEDIATED EFFECTOR FUNCTIONS: MOLECULAR DEFINITION OF INTERACTION SITES FOR EFFECTOR LIGANDS AND THE ROLE OF GLYCOSYLATION", IMMUNOLOGICAL REVIEWS, MUNKSGAARD, XX, (19980601), vol. 163, ISSN 0105-2896, pages 59 - 76, XP001203450 [A] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1111/j.1600-065X.1998.tb01188.x
 [A]  - BOBROWICZ PIOTR ET AL, "Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose.", GLYCOBIOLOGY SEP 2004, (200409), vol. 14, no. 9, ISSN 0959-6658, pages 757 - 766, XP002492957 [A] 1-14

DOI:   http://dx.doi.org/10.1093/glycob/cwh104
 [T]  - LI HUIJUAN ET AL, "Optimization of humanized IgGs in glycoengineered Pichia pastoris.", NATURE BIOTECHNOLOGY FEB 2006, (200602), vol. 24, no. 2, ISSN 1087-0156, pages 210 - 215, XP002493048

DOI:   http://dx.doi.org/10.1038/nbt1178
International search[X]US2001036647  (CHOUDARY PRABHAKARA V [US], et al);
 [Y]  - BREKKE ET AL., NATURE REVIEWS, (200301), vol. 2, pages 52 - 62, XP003009494

DOI:   http://dx.doi.org/10.1038/nrd984
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.