EP1937305 - IMMUNOGLOBULIN COMPRISING PREDOMINANTLY A MAN7GLCNAC2, MAN8GLCNAC2 GLYCOFORM [Right-click to bookmark this link] | Status | The application has been withdrawn Status updated on 28.11.2008 Database last updated on 15.06.2024 | Most recent event Tooltip | 07.08.2009 | Change - representative | published on 09.09.2009 [2009/37] | Applicant(s) | For all designated states GlycoFi, Inc. 21 Lafayette Street, Suite 200 Lebanon, NH 03766 / US | [N/P] |
Former [2008/27] | For all designated states GlycoFi, Inc. 21 Lafayette Street, Suite 200 Lebanon New Hampshire 03766 / US | Inventor(s) | 01 /
GERNGROSS, Tillman 2 Parkway Hanover, NH 03755 / US | 02 /
WILDT, Stefan 32 Parkhurst Street Lebanon, NH 03766 / US | 03 /
LI, Huijuan 8 Barden Hill Road Lebanon, NH 03766 / US | [2008/27] | Representative(s) | Buchan, Gavin MacNicol Merck Sharp & Dohme Limited European Patent Department Hertford Road Hoddesdon Hertfordshire EN11 9BU / GB | [N/P] |
Former [2009/37] | Buchan, Gavin MacNicol Merck Sharp & Dohme Limited European Patent Department Hertford Road Hoddesdon Hertfordshire EN11 9BU / GB | ||
Former [2008/27] | Buchan, Gavin MacNicol Merck & Co., Inc. Hertford Road Hoddesdon, Herts. EN11 9BU / GB | Application number, filing date | 05786499.3 | 09.09.2005 | [2008/27] | WO2005IB52964 | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2007029054 | Date: | 15.03.2007 | Language: | EN | [2007/11] | Type: | A1 Application with search report | No.: | EP1937305 | Date: | 02.07.2008 | Language: | EN | The application published by WIPO in one of the EPO official languages on 15.03.2007 takes the place of the publication of the European patent application. | [2008/27] | Search report(s) | International search report - published on: | US | 15.03.2007 | (Supplementary) European search report - dispatched on: | EP | 05.09.2008 | Classification | IPC: | A61K39/395, C07K14/00 | [2008/27] | CPC: |
C07K16/2887 (EP,US);
C07K16/00 (EP,US);
C07K2317/24 (EP,US);
C07K2317/41 (EP,US);
C07K2317/72 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2008/27] | Extension states | AL | Not yet paid | BA | Not yet paid | HR | Not yet paid | MK | Not yet paid | YU | Not yet paid | Title | German: | IMMUNGLOBULIN, DAS VORWIEGEND EINE MAN7GLCNAC2, MAN8GLCNAC2 GLYCOFORM ENTHÄLT | [2008/27] | English: | IMMUNOGLOBULIN COMPRISING PREDOMINANTLY A MAN7GLCNAC2, MAN8GLCNAC2 GLYCOFORM | [2008/27] | French: | IMMUNOGLOBULINE COMPRENANT UNE GLYCOFORME À PRÉDOMINANCE MAN7GLCNAC2 OU MAN8GLCNAC2 | [2008/27] | Entry into regional phase | 09.04.2008 | National basic fee paid | 09.04.2008 | Search fee paid | 09.04.2008 | Designation fee(s) paid | 09.04.2008 | Examination fee paid | Examination procedure | 04.03.2008 | Amendment by applicant (claims and/or description) | 09.04.2008 | Examination requested [2008/27] | 10.11.2008 | Despatch of a communication from the examining division (Time limit: M04) | 19.11.2008 | Application withdrawn by applicant [2009/01] | Fees paid | Renewal fee | 09.04.2008 | Renewal fee patent year 03 | 27.03.2008 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]WO0200879 (GLYCOFI INC [US]) [A] 1-14; | [A]WO03056914 (GLYCOFI INC [US], et al) [A] 1-14; | [X] - KO KISUNG ET AL, "Function and glycosylation of plant-derived antiviral monoclonal antibody.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 24 JUN 2003, (20030624), vol. 100, no. 13, ISSN 0027-8424, pages 8013 - 8018, XP002996058 [X] 1-8,10-12,14 * abstract * * figure 3 * * page 8016, column L, paragraph L * DOI: http://dx.doi.org/10.1073/pnas.0832472100 | [X] - TRIGUERO ADA ET AL, "Plant-derived mouse IgG monoclonal antibody fused to KDEL endoplasmic reticulum-retention signal is N-glycosylated homogeneously throughout the plant with mostly high-mannose-type N-glycans.", PLANT BIOTECHNOLOGY JOURNAL JUL 2005, (200507), vol. 3, no. 4, ISSN 1467-7652, pages 449 - 457, XP002492954 [X] 1-8,10-12,14 * table 2 * * abstract * DOI: http://dx.doi.org/10.1111/j.1467-7652.2005.00137.x | [X] - SRIRAMAN RAJAN ET AL, "Recombinant anti-hCG antibodies retained in the endoplasmic reticulum of transformed plants lack core-xylose and core-alpha(1,3)-fucose residues.", PLANT BIOTECHNOLOGY JOURNAL JUL 2004, (200407), vol. 2, no. 4, ISSN 1467-7652, pages 279 - 287, XP002492955 [X] 1-8,10-12,14 * figure 4 * * abstract * DOI: http://dx.doi.org/10.1111/j.1467-7652.2004.00078.x | [X] - ARNOLD JAMES N ET AL, "The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 1 DEC 2004, (20041201), vol. 173, no. 11, ISSN 0022-1767, pages 6831 - 6840, XP002492956 [X] 1,8,12,14 * table IV * * abstract * | [X] - ROTHMAN R J ET AL, "Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylation", MOLECULAR IMMUNOLOGY, ELMSFORD, NY, US, (19891201), vol. 26, no. 12, ISSN 0161-5890, pages 1113 - 1123, XP002435543 [X] 1-14 * figures 3,5 * * abstract * DOI: http://dx.doi.org/10.1016/0161-5890(89)90055-2 | [A] - ELBEIN A D, "GLYCOSIDASE INHIBITORS: INHIBITORS OF N-LINKED OLIGOSACCHARIDE PROCESSING", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, BETHESDA, MD, (19910101), vol. 5, no. 5, ISSN 0892-6638, pages 3055 - 3063, XP001194418 [A] 1-14 | [A] - UMANA P ET AL, "ENGINEERED GLYCOFORMS OF AN ANTINEUROBLASTOMA IGG1 WITH OPTIMIZED ANTIBODY-DEPENDENT CELLULAR CYTOTOXIC ACTIVITY", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (19990201), vol. 17, ISSN 1087-0156, pages 176 - 180, XP002921620 [A] 1-14 * the whole document * DOI: http://dx.doi.org/10.1038/6179 | [A] - JEFFERIS R ET AL, "IGG-FC-MEDIATED EFFECTOR FUNCTIONS: MOLECULAR DEFINITION OF INTERACTION SITES FOR EFFECTOR LIGANDS AND THE ROLE OF GLYCOSYLATION", IMMUNOLOGICAL REVIEWS, MUNKSGAARD, XX, (19980601), vol. 163, ISSN 0105-2896, pages 59 - 76, XP001203450 [A] 1-14 * the whole document * DOI: http://dx.doi.org/10.1111/j.1600-065X.1998.tb01188.x | [A] - BOBROWICZ PIOTR ET AL, "Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose.", GLYCOBIOLOGY SEP 2004, (200409), vol. 14, no. 9, ISSN 0959-6658, pages 757 - 766, XP002492957 [A] 1-14 DOI: http://dx.doi.org/10.1093/glycob/cwh104 | [T] - LI HUIJUAN ET AL, "Optimization of humanized IgGs in glycoengineered Pichia pastoris.", NATURE BIOTECHNOLOGY FEB 2006, (200602), vol. 24, no. 2, ISSN 1087-0156, pages 210 - 215, XP002493048 DOI: http://dx.doi.org/10.1038/nbt1178 | International search | [X]US2001036647 (CHOUDARY PRABHAKARA V [US], et al); | [Y] - BREKKE ET AL., NATURE REVIEWS, (200301), vol. 2, pages 52 - 62, XP003009494 DOI: http://dx.doi.org/10.1038/nrd984 |