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EP About this file: EP1841883

EP1841883 - A METHOD FOR ANALYZING NUCLEOBASES ON A SINGLE MOLECULAR BASIS [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 06.11.2015 Database last updated on 24.08.2024
Most recent event Tooltip	06.11.2015	Application deemed to be withdrawn	published on 09.12.2015 [2015/50]
Applicant(s)	For all designated states Japan Science and Technology Agency 1-8, Honcho 4-chome Kawaguchi-shi, Saitama 332-0012 / JP
	[2007/41]
Inventor(s)	01 / Umezawa, Yoshio 45-1-203, Ichigaya Yakuoji-machi Shinjuku-ku, Tokyo 162-0063 / JP
	02 / Ohshiro, Takahito Room 13, Kagawa-so 6-5-10, Hongo Bunkyo-ku Tokyo 113-0033 / JP
	[2007/41]
Representative(s)	Calamita, Roberto Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD / GB
	[N/P]
Former [2007/41]	Calamita, Roberto Frank B. Dehn & Co. St Bride's House 10 Salisbury Square London EC4Y 8JD / GB
Application number, filing date	05824471.6	28.12.2005
	[2007/41]
	WO2005JP24285
Priority number, date	JP20040381406	28.12.2004 Original published format: JP 2004381406
	[2007/41]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2006070946
	Date:	06.07.2006
	Language:	EN
	[2006/27]
	Type:	A1 Application with search report
	No.:	EP1841883
	Date:	10.10.2007
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 06.07.2006 takes the place of the publication of the European patent application.
	[2007/41]
Search report(s)	International search report - published on:	JP	06.07.2006
	(Supplementary) European search report - dispatched on:	EP	26.01.2009
Classification	IPC:	C12Q1/68, G01N33/53, G01N33/566	[2015/11]
	CPC:	G01Q60/16 (EP,US); C12Q1/6816 (EP,US); C12Q1/6869 (EP,US); G01Q70/18 (EP,US); Y10T436/143333 (EP,US)
	C-Set:	C12Q1/6816, C12Q2565/601 (EP,US); C12Q1/6869, C12Q2565/601 (US,EP)
	Former IPC [2007/41]	C12Q1/68, G01N13/12, G01N33/53, G01N33/566
Designated contracting states	DE, FR, GB, NL, SE [2008/14]
Former [2007/41]	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR
Extension states	AL	Not yet paid
	BA	Not yet paid
	HR	Not yet paid
	MK	Not yet paid
	YU	Not yet paid
Title	German:	VERFAHREN ZUR ANALYSE VON NUKLEOBASEN AUF EINZELMOLEKÜLBASIS	[2007/41]
	English:	A METHOD FOR ANALYZING NUCLEOBASES ON A SINGLE MOLECULAR BASIS	[2007/41]
	French:	METHODE D'ANALYSE DE NUCLEOBASES SUR UNE BASE MOLECULAIRE UNIQUE	[2007/41]
Entry into regional phase	24.07.2007	National basic fee paid
	24.07.2007	Search fee paid
	24.07.2007	Designation fee(s) paid
	24.07.2007	Examination fee paid
Examination procedure	30.10.2006	Request for preliminary examination filed International Preliminary Examining Authority: JP
	24.07.2007	Amendment by applicant (claims and/or description)
	24.07.2007	Examination requested [2007/41]
	08.05.2009	Despatch of a communication from the examining division (Time limit: M06)
	11.12.2009	Reply to a communication from the examining division
	21.06.2010	Despatch of a communication from the examining division (Time limit: M06)
	22.12.2010	Reply to a communication from the examining division
	25.05.2011	Cancellation of oral proceeding that was planned for 20.06.2011
	16.06.2011	Despatch of communication that the application is refused, reason: substantive examination {1}
	20.06.2011	Date of oral proceedings (cancelled)
	06.02.2015	Communication of intention to grant the patent
	17.06.2015	Application deemed to be withdrawn, date of legal effect [2015/50]
	23.07.2015	Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2015/50]
Appeal following examination	22.08.2011	Appeal received No. T2586/11
	25.10.2011	Statement of grounds filed
	02.12.2014	Result of appeal procedure: remittal for grant
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 08.05.2009
Request for further processing for:	The application is deemed to be withdrawn due to failure to reply to the examination report
	11.12.2009	Request for further processing filed
	11.12.2009	Full payment received (date of receipt of payment) Request granted
	04.01.2010	Decision despatched
Fees paid	Renewal fee
	20.12.2007	Renewal fee patent year 03
	29.12.2008	Renewal fee patent year 04
	23.12.2009	Renewal fee patent year 05
	28.12.2010	Renewal fee patent year 06
	21.12.2011	Renewal fee patent year 07
	19.12.2012	Renewal fee patent year 08
	20.12.2013	Renewal fee patent year 09
	18.12.2014	Renewal fee patent year 10
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X] - BOLAND T ET AL, "Direct measurement of hydrogen bonding in DNA nucleotide bases by atomic force microscopy.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 6 JUN 1995, (19950606), vol. 92, no. 12, ISSN 0027-8424, pages 5297 - 5301, XP002509911 [X] 4 * page 5297, column RIGHT * DOI: http://dx.doi.org/10.1073/pnas.92.12.5297
		[A] - UMEZAWA YOSHIO, "Seeing what was unseen: new analytical methods for molecular imaging.", CHEMICAL RECORD (NEW YORK, N.Y.) 2003, (2003), vol. 3, no. 1, ISSN 1527-8999, pages 22 - 28, XP002509912 [A] * the whole document * DOI: http://dx.doi.org/10.1002/tcr.10049
	International search	[X]GB2235049 (ROSSER ROY J, et al);
		[Y]WO0225246 (MATSUSHITA ELECTRIC IND CO LTD [JP], et al);
		[Y]JPH04330281 (MATSUSHITA ELECTRIC IND CO LTD);
		[A]JPH05244997 (HITACHI LTD)
		[Y] - NISHINOT Y. ET AL, "Selective observation of hydroxyl and carboxylate moieties by scanning tunneling microscopy using chemically midified tips with differing extents of hydrogen bond acidity or basicity", JOURNAL OF ELECTROANALYTICAL CHEMISTRY, (2003), vol. 550, no. 551, pages 125 - 129, XP002997138 DOI: http://dx.doi.org/10.1016/S0022-0728(03)00027-5
		[XP] - OSHIRO T. ET AL, "Complementary base-pair-facilitated electron tunneling for electrically pinpointing complementary nucleobases", PROC NATL ACAD SCI USA, (20060103), vol. 103, no. 1, pages 10 - 14, XP002997139 DOI: http://dx.doi.org/10.1073/pnas.0506130103
		[XP] - NISHINO T. ET AL, "Scanning tunneling microscopy with molecular chip", BUNSEKI KAGAKU, (20050605), vol. 54, no. 6, pages 417 - 426, XP002997140 DOI: http://dx.doi.org/10.2116/bunsekikagaku.54.417
		[A] - TANAKA H. ET AL, "Visualization of detailed structures within DNA", SURFACE SCIENCE, (2003), vol. 539, pages L531 - L536, XP002997141 DOI: http://dx.doi.org/10.1016/S0039-6028(03)00794-5
	Examination	- SATO Y ET AL, "In situ surface-enhanced infrared study of hydrogen bond pairing of complementary nucleic acid bases at the electrochemical interface", ANALYTICAL CHEMISTRY 20040915 AMERICAN CHEMICAL SOCIETY US, (20040915), vol. 76, no. 18, doi:10.1021/ac049303s, pages 5564 - 5569, XP009156288 DOI: http://dx.doi.org/10.1021/ac049303s
		- SATO Y ET AL, "Electrochemical responses and surface structure of gold electrodes modified with nucleic acid base derivatives", MEETING ABSTRACTS - MEETING ABSTRACTS - 205TH MEETING OF THE ELECTROCHEMICAL SOCIETY, MA 2004 01 2004 ELECTROCHEMICAL SOCIETY INC. US, (200405), page 647, XP009110525
	by applicant	- MURPHY, C. J. ET AL., "Long-range photo induced electron transfer through a DNA helix", SCIENCE, (1993), vol. 262, pages 1025 - 1029
		- PORATH, D. ET AL., "Direct measurement of electrical transport through DNA molecules", NATURE, (2000), vol. 403, doi:doi:10.1038/35001029, pages 635 - 638, XP001066504 DOI: http://dx.doi.org/10.1038/35001029
		- SCHWOGLER, A.; BURGDORF, L. T.; CARELL, T., "Self-Repairing DNA Based on a Reductive Electron Transfer through the Base Stack", ANGEW. CHEM. INT. ED., (2000), vol. 39, pages 3918 - 3920
		- DANDLIKER, P. J.; HOLMLIN, R. E.; BARTON, J. K., "Oxidative Thymine Dimer Repair in the DNA Helix", SCIENCE, (1997), vol. 275, pages 1465 - 1468
		- HALL, D. B.; HOLMLIN, R. E.; BARTON, J. K., "Oxidative DNA damage through long-range electron transfer", NATURE, (1996), vol. 382, doi:doi:10.1038/382731a0, page 731, XP002079217 DOI: http://dx.doi.org/10.1038/382731a0
		- GIESE, B., "Long-Distance Charge Transport in DNA: The Hopping Mechanism", ACC.CHEM. RES., (2000), vol. 33, pages 631 - 636
		- LEWIS, F. D.; LERSINGER, R. L.; WASIELEWSKI, M. R., "Dynamics of Photoinduced Charge Transfer and Hole Transport in Synthetic DNA Hairpins", ACC. CHEM. RES., (2001), vol. 34, pages 159 - 170
		- FINK, H.-W.; SCHONENBERGER, C., "Electrical conduction through DNA molecules", NATURE, (1999), vol. 398, doi:doi:10.1038/18855, pages 407 - 410, XP002162319 DOI: http://dx.doi.org/10.1038/18855
		- LEWIS, F. D. ET AL., "Direct measurement of hole transport dynamics in DNA", NATURE, (2000), vol. 406, pages 51 - 53
		- GROZEMA, F. C.; BERLIN, Y. A.; SIEBBELES, L. D. A., "Mechanism of Charge Migration through DNA: Molecular Wire Behavior, Single-Step Tunneling or Hopping", J. AM. CHEM. SOC., (2000), vol. 122, pages 10903 - 10909
		- WANGENKNECHT, H.-A., "Reductive Electron Transfer and Transport of Excess Electrons in DNA", ANGEW. CHEM. INT. ED., (2003), vol. 42, pages 2454 - 2460
		- BERLIN, Y. A.; BURIN, A. L.; RATNER, M. A., "Charge Hopping in DNA", J. AM. CHEM. SOC., (2001), vol. 123, pages 260 - 268
		- BARNETT, R. N. ET AL., "Charge Migration in DNA: Ion-Gated Transport", SCIENCE, (2001), vol. 294, pages 567 - 571
		- KELLY, S. O.; BARTON, J. K., "Electron Transfer Between Bases in Double Helical DNA", SCIENCE, (1999), vol. 283, pages 375 - 381
		- SESSLER, J. L. ET AL., "Hydrogen-Bond-Mediated Photoinduced Electron-Transfer: Novel Dimethylaniline-Anthracene Ensembles Formed via Watson-Crick Base-pairing", J. AM. CHEM. SOC., (2001), vol. 123, pages 3655 - 3660
		- DRETSCHKOW, T.; DAKKOURI, A. S.; WANDLOWSKI, T., "In-Situ Scanning Tunneling Microscopy Study of Uracil on Au(111) and Au(100)", LANGMUIR, (1997), vol. 13, pages 2843 - 2856
		- LI, W.-H. ET AL., "In-Situ Infrared Spectroscopic and Scanning Tunneling Microscopy Investigations of the Chemisorption Phases of Uracil, Thymine, and 3-Methyl Uracil on Au(l 11) Electrodes", LANGMUIR, (1999), vol. 15, pages 4875 - 4883
		- CHEN, Q.; FRANKEL, D. J.; RICHARDSON, N. V., "Self-Assembly of Adenine on Cu(110) Surfaces", LANGMUIR, (2002), vol. 18, pages 3219 - 3225
		- AKIYAMA, R.; MATSUMOTO, T.; KAWAI, T., "A Scanning Tunneling Microscopy Study of Electrostatic and Proximity Effects in Tip-Assisted Migration and Desorption of a DNA Base Molecule on SrTi03", J. PHYS. CHEM. B., (1999), vol. 103, pages 6103 - 6110
		- HAMAI, C.; TANAKA, H.; KAWAI, T., "Extended Structure of DNA Oligomer and Nucleotide Imaging Studied by Scanning Tunneling Microscopy", J: PHYS. CHEM. B., (2000), vol. 104, pages 9894 - 9897
		- TANAKA, H.; KAWAI, T., "Visualization of detailed structures within DNA", SUR. SCI. LETT., (2003), vol. 539, doi:doi:10.1016/S0039-6028(03)00794-5, pages L531 - L536, XP002997141 DOI: http://dx.doi.org/10.1016/S0039-6028(03)00794-5
		- ITO, T.; BUHLMANN, P.; UMEZAWA, Y., "Scanning Tunneling Microscopy Using Chemically Modified Tips", ANAL. CHEM., (1998), vol. 70, doi:doi:10.1021/ac970498w, pages 255 - 259, XP000733210 DOI: http://dx.doi.org/10.1021/ac970498w
		- ITO, T.; BUHLMANN, P.; UMEZAWA, Y., "Polypyrrole-Modified Tips for Functional Group Recognition in Scanning Tunneling Microscopy", ANAL. CHEM., (1999), vol. 71, doi:doi:10.1021/ac980689e, pages 1699 - 1705, XP000831558 DOI: http://dx.doi.org/10.1021/ac980689e
		- NISHINO, T.; ITO, T.; UMEZEWA, Y., "Scanning Tunneling Microscopy with Chemically Modified tips; orientation sensitive observation of ether oxygen", SUR. SCI. LETT., (2001), vol. 490, pages L579 - L584
		- NISHINO, T. ET AL., "Discrimination of functional groups with scanning tunneling microscopy using chemically modified tips : Recognition of ether oxygens through hydrogen bond interactions", PHYS. CHEM. CHEM. PHYS., (2001), vol. 3, pages 1867 - 1869
		- OHSHIRO, T. ET AL., "Scanning Tunneling Microscopy with Chemically Modified Tips: Discrimination of Porphyrin Centers Based on Metal Coordination and Hydrogen Bond Interactions", ANAL. CHEM., (2001), vol. 73, doi:doi:10.1021/ac001056e, pages 878 - 883, XP001059535 DOI: http://dx.doi.org/10.1021/ac001056e
		- NISHINO, T.; ITO, T.; UMEZEWA, Y., "Carbon Nanotube Scanning Tunneling Microscopy Tips for Chemically Selective Imaging", ANAL. CHEM., (2002), vol. 74, doi:doi:10.1021/ac020215m, pages 4275 - 4278, XP001132781 DOI: http://dx.doi.org/10.1021/ac020215m
		- NISHINO, T.; ITO, T.; UMEZAWA, Y., "Selective observation of hydroxy and carboxylate moieties by scanning tunneling microscopy using chemically modified tips with differing extents of hydrogen bond acidity or basicity", J. ELECTROANAL. CHEM., (2003), vol. 550, pages 125 - 129
		- NIELSEN, P. E. ET AL., "Sequence-Selective Recognition of DNA By Strand Displacement With a Thymine-Substituted Polyamide", SCIENCE, (1991), vol. 254, doi:doi:10.1126/science.1962210, pages 1497 - 1500, XP002912953 DOI: http://dx.doi.org/10.1126/science.1962210

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