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Extract from the Register of European Patents

EP About this file: EP1951739

EP1951739 - AN IMPROVED PROCESS FOR THE ISOLATION OF ARJUNIC ACID FROM THE BARK OF THE TREE TERMINALIA ARJUNA AND THE USE OF THIS COMPOUND IN THE TREATMENT OF CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  03.02.2012
Database last updated on 12.10.2024
Most recent event   Tooltip04.10.2013Lapse of the patent in a contracting state
New state(s): HU		published on 06.11.2013  [2013/45]
Applicant(s)For all designated states
Council of Scientific & Industrial Research
Anusandhan Bhawan 2, Rafi Marg
New Delhi 110 001 / IN
[2011/13]
Former [2008/32]For all designated states
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
Intellectual Property Management Division Niscaire Building, 3rd Floor 14, Satsang, Vihar Marg Special Institutional Area
110 067 New Delhi / IN
Inventor(s)01 / KHANUJA, Suman Preet Singh
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
02 / GUPTA, Madan Mohan
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
03 / SRIVASTAVA, Santosh Kumar
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
04 / KUMAR, Tiruppadiripuliyur Ranganathan Santha
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
05 / SINGH, Digvijay
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
06 / VERMA, Subash Chandra
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
07 / GARG, Ankur
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
08 / KHAN, Merajuddin
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
09 / VERMA, Ram Kishor
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
10 / MISHRA, Raghavendra Kumar
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
11 / SINGH, Subhash Chandra
Central Institute Of Medicinal And Aromatic Plants , P.O. CIMAP; Picnic Spot Road
Lucknow 226 015 / IN
 [2008/32]
Representative(s)Richaud, Fabien, et al
Murgitroyd & Company
Immeuble Atlantis
55, Allée Pierre Ziller
06560 Valbonne Sophia Antipolis / FR
[N/P]
Former [2009/52]Richaud, Fabien, et al
Murgitroyd & Company Immeuble Atlantis 55, Allée Pierre Ziller
06560 Valbonne Sophia Antipolis / FR
Former [2008/32]Anderson, Angela Mary, et al
MURGITROYD & COMPANY Immeuble Atlantis 55 Allée Pierre Ziller 06560 Valbonne
Sophia Antipolis / FR
Application number, filing date05850949.827.12.2005
[2008/32]
WO2005IN00437
Priority number, dateINDE3160200525.11.2005         Original published format: IN DE31602005
[2008/32]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007060684
Date:31.05.2007
Language:EN
[2007/22]
Type: A1 Application with search report 
No.:EP1951739
Date:06.08.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 31.05.2007 takes the place of the publication of the European patent application.
[2008/32]
Type: B1 Patent specification 
No.:EP1951739
Date:30.03.2011
Language:EN
[2011/13]
Search report(s)International search report - published on:EP31.05.2007
ClassificationIPC:C07J63/00, A61K31/56, A61P35/00
[2008/32]
CPC:
C07J63/008 (EP,US); A61P35/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/32]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:VERBESSERTES VERFAHREN ZUR ISOLIERUNG VON ARJUNASÄURE AUS DER RINDE DES BAUMS TERMINALIA ARJUNA UND DIE VERWENDUNG DIESER VERBINDUNG BEI DER BEHANDLUNG VON KREBS[2008/32]
English:AN IMPROVED PROCESS FOR THE ISOLATION OF ARJUNIC ACID FROM THE BARK OF THE TREE TERMINALIA ARJUNA AND THE USE OF THIS COMPOUND IN THE TREATMENT OF CANCER[2008/32]
French:PROCEDE AMELIORE UTILISE POUR ISOLER L'ACIDE ARJUNIQUE PRESENT DANS L'ECORCE DE L'ARBRE TERMINALIA ARJUNA ET UTILISATION DE CE COMPOSE DANS LE TRAITEMENT DU CANCER[2008/32]
Entry into regional phase14.04.2008National basic fee paid 
14.04.2008Designation fee(s) paid 
14.04.2008Examination fee paid 
Examination procedure18.12.2006Request for preliminary examination filed
International Preliminary Examining Authority: EP
14.04.2008Examination requested  [2008/32]
02.06.2008Amendment by applicant (claims and/or description)
24.07.2009Despatch of a communication from the examining division (Time limit: M06)
03.02.2010Reply to a communication from the examining division
10.09.2010Communication of intention to grant the patent
31.12.2010Fee for grant paid
31.12.2010Fee for publishing/printing paid
Opposition(s)02.01.2012No opposition filed within time limit [2012/10]
Fees paidRenewal fee
14.04.2008Renewal fee patent year 03
08.12.2008Renewal fee patent year 04
23.12.2009Renewal fee patent year 05
20.12.2010Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
HU30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
TR30.03.2011
BG30.06.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
IE27.12.2011
LU27.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
[2013/45]
Former [2013/44]AT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
TR30.03.2011
BG30.06.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
IE27.12.2011
LU27.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
Former [2013/29]AT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
BG30.06.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
IE27.12.2011
LU27.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
Former [2013/25]AT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
IE27.12.2011
LU27.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
Former [2012/49]AT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
IE27.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
Former [2012/47]AT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
IE27.12.2011
MC31.12.2011
Former [2012/33]AT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
MC31.12.2011
Former [2012/24]AT30.03.2011
BE30.03.2011
CY30.03.2011
CZ30.03.2011
DK30.03.2011
EE30.03.2011
FI30.03.2011
IT30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
PL30.03.2011
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SE30.03.2011
SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
Former [2012/11]AT30.03.2011
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CZ30.03.2011
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GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
Former [2012/10]AT30.03.2011
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SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
Former [2012/02]AT30.03.2011
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CY30.03.2011
CZ30.03.2011
EE30.03.2011
FI30.03.2011
LT30.03.2011
LV30.03.2011
NL30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
PL22.08.2011
Former [2011/50]AT30.03.2011
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CZ30.03.2011
EE30.03.2011
FI30.03.2011
LT30.03.2011
LV30.03.2011
RO30.03.2011
SE30.03.2011
SI30.03.2011
SK30.03.2011
GR01.07.2011
ES11.07.2011
IS30.07.2011
PT01.08.2011
PL22.08.2011
Former [2011/47]AT30.03.2011
BE30.03.2011
CY30.03.2011
EE30.03.2011
FI30.03.2011
LT30.03.2011
LV30.03.2011
SE30.03.2011
SI30.03.2011
GR01.07.2011
PT01.08.2011
Former [2011/41]AT30.03.2011
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CY30.03.2011
FI30.03.2011
LT30.03.2011
LV30.03.2011
SE30.03.2011
SI30.03.2011
GR01.07.2011
Former [2011/40]AT30.03.2011
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FI30.03.2011
LT30.03.2011
LV30.03.2011
SE30.03.2011
SI30.03.2011
GR01.07.2011
Former [2011/37]CY30.03.2011
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LT30.03.2011
LV30.03.2011
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Cited inInternational search[A]GB1493926  (INVERNI DELLA BEFFA SPA) [A] 1-11 * example 1 *;
 [A]  - ROW L R ET AL, "CHEMICAL EXAMINATION OF TERMINALIA-D SPECIES PART 12 ISOLATION AND STRUCTURE DETERMINATION OF ARJUNIC-ACID A NEW TRI HYDROXYTRI TERPENE CARBOXYLIC-ACID FROM TERMINALIA-ARJUNA-D BARK", INDIAN JOURNAL OF CHEMISTRY, (1970), vol. 8, no. 8, ISSN 0019-5103, pages 716 - 721, XP008067927 [A] 1-11 * page 719, column 2, paragraph 3 - page 720, column 1, paragraph 2 *
 [A]  - SINGH D V ET AL, "Arjunetin from Terminalia arjuna as an insect feeding-deterrent and growth inhibitor.", PHYTOTHERAPY RESEARCH : PTR. FEB 2004, (200402), vol. 18, no. 2, ISSN 0951-418X, pages 131 - 134, XP002395524 [A] 1-11 * page 131, column 2, paragraph 3 - page 132, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1002/ptr.1383
 [A]  - SINGH D V ET AL, "RP-LC determination of oleane derivatives in Terminalia arjuna.", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 15 MAY 2002, (20020515), vol. 28, no. 3-4, ISSN 0731-7085, pages 447 - 452, XP002395525 [A] 1-11 * page 448, column 1, paragraph 3 *

DOI:   http://dx.doi.org/10.1016/S0731-7085(01)00590-8
 [A]  - CHEN FENG-ZHENG ET AL, "Chemical constituents from fruits of Rosa davidii", ACTA BOTANICA SINICA, (200101), vol. 43, no. 1, ISSN 0577-7496, pages 101 - 104, XP008067951 [A] 1-11 * page 102, column 2, paragraph 3 *
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 [X]  - ZHANG, HAILONG ET AL, "Chemical constituents and pharmacological development of Terminalia chebula Retz.", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 2002:3524, URL: STN, XP002408539 [X] 12-27 * abstract *
 [XY]  - LEE, TZONG-HUEI ET AL, "Monoterpene Glycosides and Triterpene Acids from Eriobotrya deflexa", JOURNAL OF NATURAL PRODUCTS , 64(7), 865-869 CODEN: JNPRDF; ISSN: 0163-3864, (2001), XP002408530 [X] 12,13,20 * page 866; compounds 5,7,8,9 * * page 867, column 1, paragraph 1 * [Y] 12-27

DOI:   http://dx.doi.org/10.1021/np0100237
 [XY]  - SUMITRA M ET AL, "Experimental myocardial necrosis in rats: Role of arjunolic acid on platelet aggregation, coagulation and antioxidant status", MOLECULAR AND CELLULAR BIOCHEMISTRY 2001 NETHERLANDS, (2001), vol. 224, no. 1-2, ISSN 0300-8177, pages 135 - 142, XP002408531 [X] 12,13 * page 136, column 1, paragraph L * * page 141, column 1, paragraph L - column 2, paragraph 1 * [Y] 12-27

DOI:   http://dx.doi.org/10.1023/A:1011927812753
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DOI:   http://dx.doi.org/10.1016/S0367-326X(01)00295-7
 [X]  - ADNYANA, I. KETUT ET AL, "Three new triterpenes from the seeds of combretum quadrangulare and their hepatoprotective activity", JOURNAL OF NATURAL PRODUCTS , 64(3), 360-363 CODEN: JNPRDF; ISSN: 0163-3864, (2001), XP002408533 [X] 12,13 * page 362, column 2; table 1 *

DOI:   http://dx.doi.org/10.1021/np000486x
 [X]  - SIVALOKANATHAN S ET AL, "Efficacy of Terminalia arjuna (Roxb.) on N-nitrosodiethylamine induced hepatocellular carcinoma in rats.", INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY. MAR 2005, (200503), vol. 43, no. 3, ISSN 0019-5189, pages 264 - 267, XP008071774 [X] 12-27 * page 265, column 1, paragraph 2 * * page 265, column 2, paragraph L * * page 266, column 2, paragraph L *
 [X]  - KAUR S ET AL, "Antimutagenic potential of extracts isolated from Terminalia arjuna", EMBASE, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (2001), Database accession no. EMB-2001050231, XP002408540 [X] 12-27 * abstract *
    [ ] - JOURNAL OF ENVIRONMENTAL PATHOLOGY, TOXICOLOGY AND ONCOLOGY 2001 UNITED STATES, (2001), vol. 20, no. 1, ISSN 0731-8898, pages 9 - 14
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DOI:   http://dx.doi.org/10.1007/s11010-006-0433-8
 [L]  - URL: http://www.springerlink.com/content/y0t6782616826464/, (20061122), XP002408792 [L] * This document demonstrates that the article in Mol. Cell. Biol. Vol 281(1-2) pages 87-93, was pre-published on the Internet on 03 December 2005 - in the priority period of the present application. *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.