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Extract from the Register of European Patents

EP About this file: EP1845166

EP1845166 - Nucleic acid probes with covalently bound intercalating fluorescent dyes for hybridization with target nucleic acids [Right-click to bookmark this link]
Status	The application has been refused Status updated on 16.03.2012 Database last updated on 20.07.2024
Most recent event Tooltip	16.03.2012	Refusal of application	published on 18.04.2012 [2012/16]
Applicant(s)	For all designated states BioSpring GmbH Alt Fechenheim 34 60386 Frankfurt / DE
	[2007/42]
Inventor(s)	01 / Aygün, Hüseyin, Dr. Fürstenbergstrasse 158 60322 Frankfurt am Main / DE
	[2007/42]
Representative(s)	Keller, Günter, et al Lederer & Keller Patentanwälte Partnerschaft mbB Unsöldstrasse 2 80538 München / DE
	[N/P]
Former [2007/42]	Keller, Günter, et al Lederer & Keller Patentanwälte Prinzregentenstrasse 16 80538 München / DE
Application number, filing date	06007829.2	13.04.2006
	[2007/42]
Filing language	DE
Procedural language	DE
Publication	Type:	A1 Application with search report
	No.:	EP1845166
	Date:	17.10.2007
	Language:	DE
	[2007/42]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	06.10.2006
Classification	IPC:	C12Q1/68	[2007/42]
	CPC:	C12Q1/6851 (EP); C12Q1/6816 (EP)
	C-Set:	C12Q1/6816, C12Q2563/131, C12Q2563/173 (EP); C12Q1/6851, C12Q2563/173, C12Q2563/131, C12Q2561/113 (EP)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2007/42]
Title	German:	Neue Nukleinsäuresonden mit kovalent gebundenen, interkalierenden Fluoreszenzfarbstoffen zur Hybridisierung an Nukleinsäureproben	[2007/42]
	English:	Nucleic acid probes with covalently bound intercalating fluorescent dyes for hybridization with target nucleic acids	[2007/42]
	French:	Sonde acide nucléique liée covalentement avec un colorant fluorescent intercalant pour l' hybridation avec des acides nucléiques termes	[2007/42]
Examination procedure	19.03.2008	Examination requested [2008/19]
	27.05.2008	Despatch of a communication from the examining division (Time limit: M06)
	05.12.2008	Reply to a communication from the examining division
	21.06.2010	Despatch of a communication from the examining division (Time limit: M04)
	20.10.2010	Reply to a communication from the examining division
	12.10.2011	Application refused, date of legal effect [2012/16]
	12.10.2011	Date of oral proceedings
	01.12.2011	Despatch of communication that the application is refused, reason: substantive examination [2012/16]
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 27.05.2008
Fees paid	Renewal fee
	28.02.2008	Renewal fee patent year 03
	30.03.2009	Renewal fee patent year 04
	25.02.2010	Renewal fee patent year 05
	28.04.2011	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A]US5869236 (DUPRET DANIEL [FR], et al) [A] 1-20 * the whole document *;
		[A]US6140054 (WITTWER CARL T [US], et al) [A] 1-20 * the whole document *;
		[A]EP1055734 (TOSOH CORP [JP]) [A] 1-20* the whole document *;
		[A]US6346386 (ELENITOBA-JOHNSON KOJO S J [US]) [A] 1-20 * the whole document *;
		[X]WO03043402 (PROLIGO LLC [US]) [X] 1-20 * claims 41,42 *;
		[X]EP1375674 (TOSOH CORP [JP]) [X] 1-20 * paragraphs [0004] , [0005]; examples 1,2 *;
		[A]WO2005012579 (MOLECULAR PROBES INC [US], et al) [A] 1-20 * the whole document *;
		[X]EP1577318 (NGK INSULATORS LTD [JP], et al) [X] 1-20 * paragraphs [0010] , [0019] , [0020] , [0036] , [0038]; claims 1,10 *;
		[X] - SHINOZUKA K ET AL, "Novel Multifunctionalit Labelled DNA Probe Bearing an Intercalator and a Fluorophore", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS, CHEMICAL SOCIETY. LETCHWORTH, GB, (1994), vol. 11, ISSN 0022-4936, pages 1377 - 1378, XP002118883 [X] 1-20 * abstract * DOI: http://dx.doi.org/10.1039/c39940001377
		[A] - SAITOH J ET AL, "SEQUENCE SPECIFIC HOMOGENEOUS DETECTION OF HCV RNA BY FLUORESCENCE MONITORING OF IN VITRO TRANSCRIPTION WITH INTERCALATOR-LINKED OLIGONUCLEOTIDE PROBE", NUCLEIC ACIDS SYMPOSIUM SERIES, IRL PRESS, OXFORD, GB, (1997), no. 37, ISSN 0261-3166, pages 113 - 114, XP001097284 [A] 1-20 * the whole document *
		[A] - RIRIE K M ET AL, "PRODUCT DIFFERENTIATION BY ANALYSIS OF DNA MELTING CURVES DURING THE POLYMERASE CHAIN REACTION", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS, SAN DIEGO, CA, US, (1997), vol. 245, no. 2, ISSN 0003-2697, pages 154 - 160, XP001015991 [A] 1-20 * the whole document * DOI: http://dx.doi.org/10.1006/abio.1996.9916
		[A] - TAYA T ET AL, "HOMOGENEOUS DETECTION OF A TARGET NUCLEIC ACID SEQUENCE BY COMBINATION OF THE INTERCALATION ACTIVATING FLUORESCENCE DNA PROBE AND THE ISOTHERMAL SEQUENCE AMPLIFICATION", NUCLEIC ACIDS SYMPOSIUM SERIES, IRL PRESS, OXFORD, GB, (1999), vol. 42, ISSN 0261-3166, pages 51 - 52, XP001135170 [A] 1-20 * the whole document *
	Examination	WO03052134

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