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Extract from the Register of European Patents

EP About this file: EP1738759

EP1738759 - Inhibition of abnormal cell proliferation with camptothecin and combinations including the same [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  09.05.2008
Database last updated on 19.07.2024
Most recent event   Tooltip09.05.2008Application deemed to be withdrawnpublished on 11.06.2008  [2008/24]
Applicant(s)For all designated states
SuperGen, Inc.
4140 Dublin Boulevard, Suite 200
Dublin, California 94568 / US
[2007/01]
Inventor(s)01 / Rubinfeld, Joseph
5304 Blackhawk Drive
Danville, CA 94506 / US
 [2007/01]
Representative(s)Gallagher, Kirk James, et al
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
[N/P]
Former [2007/01]Gallagher, Kirk James, et al
D Young & Co 120 Holborn
London EC1N 2DY / GB
Application number, filing date06021027.519.04.2001
[2007/01]
Priority number, dateUS2000055371020.04.2000         Original published format: US 553710
[2007/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1738759
Date:03.01.2007
Language:EN
[2007/01]
Search report(s)(Supplementary) European search report - dispatched on:EP29.11.2006
ClassificationIPC:A61K31/437, A61P35/00
[2007/01]
CPC:
A61K45/06 (EP,US); A61K31/44 (EP,US); A61K31/4745 (EP,US);
A61K31/70 (EP,US); A61P35/00 (EP)
C-Set:
A61K31/44, A61K2300/00 (US,EP);
A61K31/4745, A61K2300/00 (EP,US);
A61K31/70, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2007/01]
TitleGerman:Hemmung von abnormaler Zellvermehrung durch Camptothecin und Kombinationen dieses enthaltend[2007/01]
English:Inhibition of abnormal cell proliferation with camptothecin and combinations including the same[2007/01]
French:Inhibition de la prolifération cellulaire anormale avec de la camptothecine et des combinaisons contenant ledit composé[2007/01]
Examination procedure18.10.2006Examination requested  [2007/01]
13.08.2007Despatch of a communication from the examining division (Time limit: M04)
29.12.2007Application deemed to be withdrawn, date of legal effect  [2008/24]
25.01.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/24]
Parent application(s)   TooltipEP01930607.5  / EP1276479
Fees paidRenewal fee
18.10.2006Renewal fee patent year 03
18.10.2006Renewal fee patent year 04
18.10.2006Renewal fee patent year 05
18.10.2006Renewal fee patent year 06
27.04.2007Renewal fee patent year 07
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Documents cited:Search[X]US5786344  (RATAIN MARK J [US], et al) [X] 1-15,26-28 * see in particular examples 1, 2, 14, 15, 20, 24, 29; claims 1, 3, 10, 15-17, 24, 26 *;
 [E]WO0128542  (SUPERGEN INC [US], et al) [E] 1-15,26-28 * see in particular the claims *;
 [X]  - GIOVANELLA B ET AL, "Treatment of human cancer xenografts with camptothecin analogues in combination with cytoxan or x-irradiation.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL, 85th Annual Meeting of the American Association for Cancer Research;San Francisco, California, USA; April 10-13, 1994, 1994, (1994), vol. 35, ISSN 0197-016X, page 454, XP001064595 [X] 1,2,13-15,26-28 * see the abstract *
 [X]  - NAIK HARMESH ET AL, "Inhibition of prostate cancer growth by 9-aminocamptothecin and estramustine.", UROLOGY, (1996), vol. 48, no. 3, ISSN 0090-4295, pages 508 - 511, XP001069434 [X] 1,2,13-15,26-28 * see in particular the abstract; figures 2 and 3; p. 511, left column - right column, first paragraph *

DOI:   http://dx.doi.org/10.1016/S0090-4295(96)00201-4
 [X]  - CIESIELSKI M J ET AL, "Combination therapy with 9-aminocamptothecin (9-AC) and etoposide (VP-16) in human glioblastoma.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL, 87th Annual Meeting of the American Association for Cancer Research;Washington, D.C., USA; April 20-24, 1996, 1996, (1996), vol. 37, ISSN 0197-016X, page 427, XP001068950 [X] 1,5,13-15,26-28 * see the abstract *
 [X]  - HORN L ET AL, "Cellular effects of 9-aminocamptothecin when combined with other chemotherapeutic agents.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL, 89th Annual Meeting of the American Association for Cancer Research;New Orleans, Louisiana, USA; March 28-April 1, 1998, March, 1998, (199803), vol. 39, ISSN 0197-016X, page 526, XP001068951 [X] 1,2,4,13-15,26-28 * see the abstract *
 [X]  - ROTHENBERG M.L., "Topoisomerase I inhibitors: Review and update.", ANNALS OF ONCOLOGY, (1997), vol. 8, no. 9, pages 837 - 855, XP001069433 [X] 1-15,26-28 * see in particular p. 841, left column, 3rd paragraph; p. 843, table 4; p. 846, left column, first two paragraphs; p. 846, right column, last paragraph - p. 847, left column, first paragraph *

DOI:   http://dx.doi.org/10.1023/A:1008270717294
 [X]  - SOLA FRANCESCO ET AL, "The antitumor efficacy of cytotoxic drugs is potentiated by treatment with PNU 145156E, a growth-factor-complexing molecule.", CANCER CHEMOTHERAPY AND PHARMACOLOGY, (199903), vol. 43, no. 3, ISSN 0344-5704, pages 241 - 246, XP002104215 [X] 1,13-15,26-28 * see in particular the abstract; p. 242, left column, 1st paragraph; p. 245, table 4; p. 245, left column, last paragraph - p. 246, left column, 1st paragraph *

DOI:   http://dx.doi.org/10.1007/s002800050890
 [X]  - O'LEARY JAMES J ET AL, "Antiangiogenic effects of camptothecin analogues 9-amino-20(S)-camptothecin, topotecan, and CPT-11 studied in the mouse cornea model", CLINICAL CANCER RESEARCH, ISSN: 1078-0432, (199901), vol. 5, no. 1, pages 181 - 187, XP001070226 [X] 1,5,13-15,26-28 * see in particular the abstract; p. 184, right column, l. 35-55; p. 185, table 1; p. 185, right column l. 9 - p. 186, right column, l. 2 *
by applicantUS4636195
 WO9001969
 WO9003768
 EP0383492
 US5049132
 US5286254
 US5429634
 US5464650
 US5527337
 EP0716836
 US5545208
 US5552154
 US5649977
 US5679400
 US5731316
    - WALL, M., "plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata", J. AM. CHEM. SOC., (1966), vol. 88, pages 3888 - 3890
    - "Camptothecin: Discovery to Clinic", MONROE E. WALL, 803 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, (1996), vol. 1
    - GOTTLIEB, J. A., "Preliminary pharmacological and clinical evaluation of camptothecin sodium salt (NSC 100880", CANCER CHEMOTHER. REP., (1979), vol. 54, pages 461 - 470
    - MUGGIA, F.M., "Phase I clinical trials of weekly and daily treatment with camptothecin (NSC 100880): Correlation with clinical studies", CANCER CHEMOTHER. REP., (1972), vol. 56, pages 515 - 521
    - GOTTLIEB, J. A., "Treatment of malignant melanoma with camptothecin (NSC 100880", CANCER CHEMOTHER. REP., (1972), vol. 56, pages 103 - 105
    - MOERTEL, C.G., "Phase II study of camptothecin (NSC 100880) in the treatment of advanced gastrointestinal cancer", CANCER CHEMOTHER REP., (1972), vol. 56, pages 95 - 101
    - GIOVANELLA, B. C., CANCER, (1983), vol. 52, no. 7, page 1146
    - GIOVANELLA, B.C., "Highly effective topoisomerase-I targeted chemotherapy of human colon cancer in xenografts", SCIENCE, (1989), vol. 246, pages 1046 - 1048
    - D. CHATTERJEE, "Induction of Apoptosis in Malignant and Camptothecin- resistant Human Cells", 803 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, (1996), vol. 143
    - FERRARA N.; ALITALO, K., "Clinical application of angiogenic growth factors and their inhibitors", NATURE MEDICINE, (1999), vol. 5, doi:doi:10.1038/70928, pages 1359 - 1364, XP002217702

DOI:   http://dx.doi.org/10.1038/70928
    - LANGE, SCIENCE, (199009), vol. 249, pages 1527 - 1533
    - MATHIOWITZ, J. APP. POLY SCI., (1981), vol. 26, page 809
    - LANGE, SCIENCE, vol. 249, pages 1527 - 1533
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