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Extract from the Register of European Patents

EP About this file: EP1764091

EP1764091 - Improvements in or relating to amphoteric liposomes [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.07.2018
Database last updated on 07.10.2024
FormerThe patent has been granted
Status updated on  28.07.2017
FormerGrant of patent is intended
Status updated on  09.03.2017
Most recent event   Tooltip29.05.2020Lapse of the patent in a contracting state
New state(s): PT		published on 01.07.2020  [2020/27]
Applicant(s)For all designated states
Marina Biotech, Inc.
3830 Monte Villa Parkway
Bothell WA 98021-7266 / US
[2017/35]
Former [2010/48]For all designated states
Marina Biotech, Inc.
3830 Monte Villa Parkway
Bothell WA 98021-7266 / US
Former [2007/12]For all designated states
novosom AG
Weinbergweg 22
06120 Halle / DE
Inventor(s)01 / Panzner, Steffen
Herweghstrasse 7
06114 Halle / DE
02 / Kerwitz, Yvonne
Stolberger Strasse 71
99734 Nordhausen / DE
03 / Rauchhaus, Una
Schleiermacherstrasse 12
06114 Halle / DE
04 / Lutz, Silke
Schleiermacherstrasse 33
06114 Halle / DE
05 / Endert, Gerold
Seebener Strasse 20
06114 Halle / DE
 [2017/35]
Former [2007/12]01 / Panzner, Steffen
Herwehstrasse 7
06114 Halle / DE
02 / Kerwitz, Yvonne
Stolberger Strasse 71
99734 Nordhausen / DE
03 / Rauchhaus, Una
Schleiermacherstrasse 12
06114 Halle / DE
04 / Lutz, Silke
Schleiermacherstrasse 33
06114 Halle / DE
05 / Endert, Gerold
Seebener Strasse 20
06114 Halle / DE
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2017/35]J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2013/40]Srinivasan, Ravi Chandran, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2010/48]MacLean, Martin Robert, et al
Mathys & Squire LLP 120 Holborn London
EC1N 2SQ / GB
Former [2007/12]Crump, Julian Richard John, et al
Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP The Rectory 9, Ironmonger Lane
London EC2V 8EY / GB
Application number, filing date06254821.915.09.2006
[2007/12]
Priority number, dateUS20050717291P15.09.2005         Original published format: US 717291 P
EP2005002021615.09.2005         Original published format: EP 05020216
EP2006011378410.05.2006         Original published format: EP 06113784
US2005026742304.11.2005         Original published format: US 267423
US2005026699904.11.2005         Original published format: US 266999
WO2005EP1190504.11.2005         Original published format: PCT/EP2005/011905
WO2005EP1190804.11.2005         Original published format: PCT/EP2005/011908
US20050717293P15.09.2005         Original published format: US 717293 P
EP2005002021815.09.2005         Original published format: EP 05020218
US20050717199P15.09.2005         Original published format: US 717199 P
EP2005002021715.09.2005         Original published format: EP 05020217
EP2005009032221.11.2005         Original published format: EP 05090322
[2007/12]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1764091
Date:21.03.2007
Language:EN
[2007/12]
Type: A3 Search report 
No.:EP1764091
Date:13.06.2007
[2007/24]
Type: B1 Patent specification 
No.:EP1764091
Date:30.08.2017
Language:EN
[2017/35]
Search report(s)(Supplementary) European search report - dispatched on:EP16.05.2007
ClassificationIPC:A61K9/127, A61P1/00, A61P1/04, A61P3/10, A61P5/16, A61P11/06, A61P17/06, A61P19/02, A61P25/00, A61P37/06
[2007/12]
CPC:
A61K9/1271 (EP,US); A61K47/16 (KR); A61K31/713 (EP,US);
A61K48/00 (EP,US); A61K9/0019 (EP,US); A61K9/127 (EP,KR,US);
A61K9/1272 (EP,US); A61P1/00 (EP); A61P1/04 (EP);
A61P1/16 (EP); A61P11/06 (EP); A61P17/06 (EP);
A61P19/02 (EP); A61P25/00 (EP); A61P25/28 (EP);
A61P29/00 (EP); A61P3/10 (EP); A61P35/00 (EP);
A61P37/00 (EP); A61P37/06 (EP); A61P5/14 (EP);
A61P5/16 (EP); C12N15/1138 (US); C12N15/88 (EP,US);
C12N2310/11 (US); C12N2320/32 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/35]
Former [2007/12]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Verbesserungen für, oder in Bezug auf amphotere Liposomen[2007/12]
English:Improvements in or relating to amphoteric liposomes[2007/12]
French:Améliorations sur ou concernant des liposomes amphotères[2007/12]
Examination procedure12.12.2007Examination requested  [2008/04]
19.03.2008Despatch of a communication from the examining division (Time limit: M06)
26.09.2008Reply to a communication from the examining division
27.02.2015Despatch of a communication from the examining division (Time limit: M04)
24.06.2015Reply to a communication from the examining division
03.08.2015Despatch of a communication from the examining division (Time limit: M04)
10.12.2015Reply to a communication from the examining division
08.02.2016Communication of intention to grant the patent
12.08.2016Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
14.10.2016Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
10.03.2017Communication of intention to grant the patent
20.07.2017Fee for grant paid
20.07.2017Fee for publishing/printing paid
20.07.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  19.03.2008
Opposition(s)31.05.2018No opposition filed within time limit [2018/32]
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
14.10.2016Request for further processing filed
14.10.2016Full payment received (date of receipt of payment)
Request granted
26.10.2016Decision despatched
Fees paidRenewal fee
22.09.2008Renewal fee patent year 03
28.09.2009Renewal fee patent year 04
22.09.2010Renewal fee patent year 05
30.09.2011Renewal fee patent year 06
25.09.2012Renewal fee patent year 07
27.09.2013Renewal fee patent year 08
12.09.2014Renewal fee patent year 09
11.09.2015Renewal fee patent year 10
27.02.2017Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
30.09.201611   M06   Fee paid on   27.02.2017
Opt-out from the exclusive  Tooltip
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.09.2006
AT30.08.2017
CY30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
PT30.08.2017
RO30.08.2017
SI30.08.2017
SK30.08.2017
TR30.08.2017
IE15.09.2017
LU15.09.2017
BE30.09.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
[2020/27]
Former [2020/16]HU15.09.2006
AT30.08.2017
CY30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
RO30.08.2017
SI30.08.2017
SK30.08.2017
TR30.08.2017
IE15.09.2017
LU15.09.2017
BE30.09.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2019/46]HU15.09.2006
AT30.08.2017
CY30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
RO30.08.2017
SI30.08.2017
SK30.08.2017
IE15.09.2017
LU15.09.2017
BE30.09.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2019/31]HU15.09.2006
AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
RO30.08.2017
SI30.08.2017
SK30.08.2017
IE15.09.2017
LU15.09.2017
BE30.09.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/39]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
RO30.08.2017
SI30.08.2017
SK30.08.2017
IE15.09.2017
LU15.09.2017
BE30.09.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/34]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
RO30.08.2017
SK30.08.2017
IE15.09.2017
LU15.09.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/30]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
RO30.08.2017
SK30.08.2017
LU15.09.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/26]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
PL30.08.2017
RO30.08.2017
SK30.08.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/23]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
PL30.08.2017
RO30.08.2017
SK30.08.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/21]AT30.08.2017
CZ30.08.2017
DK30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/12]AT30.08.2017
ES30.08.2017
FI30.08.2017
LT30.08.2017
LV30.08.2017
BG30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/10]AT30.08.2017
FI30.08.2017
LT30.08.2017
Former [2018/08]FI30.08.2017
LT30.08.2017
Former [2018/07]LT30.08.2017
Documents cited:Search[X]EP0795325  (APPLIED BIOCHEMISTRY INST [JP]) [X] 1-5,8 * column 1, line 52 - column 2, line 16 * * column 3, lines 9-25 * * column 4, lines 6-30 * * claims 1-4 *;
 [X]WO9849350  (UNIV MINNESOTA [US], et al) [X] 1-7 * page 1, paragraph 2 * * page 21, paragraph 4 - page 22, paragraph 1 *;
 [X]US5834012  (PEREZ-SOLER ROMAN [US], et al) [X] 1-8 * column 14, lines 11-18 * * column 15, lines 25-28 *;
 [X]WO0021370  (UNIV KENTUCKY RES FOUND [US], et al) [X] 1-11,14-17,23-39,41-47,50-55 * page 28, line 3 - page 29, line 12 * * page 68 - page 70; examples 7,8 *;
 [X]WO0059474  (ISIS PHARMACEUTICALS INC [US], et al) [X] 1-11,14-17,23-39,41-46 * page 41 - page 42; example 7 *;
 [X]WO02066013  (OPPERBAS HOLDING BV [NL], et al) [X] 1,4,5,8 * page 2, line 26 - page 3, line 12 * * page 12, lines 23-25 *;
 [DA]WO02066012  (NOVOSOM AG [DE], et al)[DA] 1-55;
 [A]US2003099697  (PANZNER STEFFEN [DE], et al) [A] 1-55 * page 1, paragraph 15 * * page 3, paragraphs 65,66,71-75 * * page 4, paragraphs 78,85,86 * * page 5; examples 1,2 * * page 7; example 9 * * page 8; example 13 *;
 [X]US2004037874  (HONG KEELUNG [US], et al) [X] 1-8 * page 3, paragraphs 31-33,37,38 * * page 5, paragraphs 48,49 * * page 6, paragraph 59 * * page 15; table 2 * * page 20, paragraph 156; example 21 *;
 [X]WO2004053118  (PROTECH RES PTY LTD [AU], et al) [X] 1-8 * page 2, lines 24-29 * * page 6, line 11 - page 7, line 28 * * page 8, lines 6-11 * * page 21 - page 22; example 5 * * page 23; table . *;
 [PXL]WO2006048329  (NOVOSOM AG [DE], et al) [PXL] 1-55 * page 1, lines 5-9 * * page 4, line 17 - page 9, line 4 * * page 9, line 27 - page 10, line 27 * * page 21, lines 1-11; tables 1,2 * * claim 25 *;
 [PX]WO2006053646  (NOVOSOM AG [DE], et al) [PX] 1-49 * page 3, line 30 - page 4, line 5 * * page 4, line 31 - page 5, line 21 * * page 6, line 5 - page 10, line 12 * * page 10, line 24 - page 12, line 29 * * page 13, lines 18-26 * * page 21 - page 23; examples 5-7 * * claims 24-29 *;
 [X]  - HAFEZ I M ET AL, "On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids", GENE THERAPY, (2001), vol. 8, pages 1188 - 1196, XP002358998 [X] 1-12,14-17,23-39,41-46 * abstract * * page 1189, column R, paragraph 2 - page 1190, column L, paragraph 2 * * page 1194, column L, paragraph 3 *

DOI:   http://dx.doi.org/10.1038/sj.gt.3301506
 [X]  - WROBEL I ET AL, "FUSION OF CATIONIC LIPOSOMES WITH MAMMALIAN CELLS OCCURS AFTER ENDOCYTOSIS", BIOCHIMICA ET BIOPHYSICA ACTA. BIOMEMBRANES, AMSTERDAM, NL, (19950504), vol. 1235, no. 2, ISSN 0005-2736, pages 296 - 304, XP000619562 [X] 1-11,14-17,23-39,41-46 * abstract * * page 296, column R, paragraph L - page 297, column L, paragraph 1 * * page 298, column R, paragraph 2 - page 299, column R, paragraph 1 * * page 303, column R, paragraph 2 *

DOI:   http://dx.doi.org/10.1016/0005-2736(95)80017-A
 [X]  - STAMATATOS L ET AL, "INTERACTIONS OF CATIONIC LIPID VESICLES WITH NEGATIVELY CHARGED PHOSPHOLIPID VESICLES AND BIOLOGICAL MEMBRANES", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, EASTON, PA, US, (19880531), vol. 27, no. 11, ISSN 0006-2960, pages 3917 - 3925, XP000601444 [X] 1-4,6-11,14-17,23-25,43-46 * abstract * * page 3919, column L, paragraph L - page 3919, column R, paragraph 1 * * page 3920, column R, paragraph 3 * * page 3921, column L, paragraph 2 * * page 3922; table I *

DOI:   http://dx.doi.org/10.1021/bi00411a005
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