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Extract from the Register of European Patents

EP About this file: EP1885749

EP1885749 - BONE MORPHOGENETIC PROTEIN 3 AND OSTEOGENIC DEVICES AND PHARMACEUTICAL PRODUCTS CONTAINING THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.06.2018
Database last updated on 13.07.2024
FormerThe patent has been granted
Status updated on  21.07.2017
FormerGrant of patent is intended
Status updated on  20.12.2016
Most recent event   Tooltip26.06.2020Lapse of the patent in a contracting state
New state(s): CY		published on 29.07.2020  [2020/31]
Applicant(s)For all designated states
BBS-Bioactive Bone Substitutes Oy
Aalentie 3
90240 Oulu / FI
[2017/34]
Former [2008/07]For all designated states
BBS-Bioactive Bone Substitutes Oy
Aalentie 3
90240 Oulu / FI
Inventor(s)01 / BIRR, Elli
Karppilantie 20
FI-90450 Kempele / FI
02 / ULMANEN, Mari
Alasniitynkatu 23 A 8
FI-33700 Tampere / FI
03 / HIETALA, Oili
Joulumerkintie 6 A 1
FI-90160 Oulu / FI
04 / JUUSTILA, Marja
Rantaharjuntie 53 B 7
FI-91980 Lumijoki / FI
05 / KORKALA, Heli
Tuulihaukantie 9 B 71
FI-90250 Oulu / FI
06 / JALOVAARA, Pekka
Aalentie 5
FI-90240 Oulu / FI
 [2008/07]
Representative(s)Berggren Oy
P.O. Box 16
Eteläinen Rautatiekatu 10A
00101 Helsinki / FI
[N/P]
Former [2017/34]Berggren Oy, Tampere
Visiokatu 1
33720 Tampere / FI
Former [2014/10]Tampereen Patenttitoimisto Oy
Hermiankatu 1 B
33720 Tampere / FI
Former [2014/08]Vanhala, Jorma Kalevi, et al
Berggren Oy Ab
Sepänkatu 20
90100 Oulu / FI
Former [2008/07]Vanhala, Jorma Kalevi
Berggren Oy Ab Lentokatu 2
90460 Oulunsalo / FI
Application number, filing date06725969.726.05.2006
[2008/07]
WO2006FI50212
Priority number, dateFI2005000525727.05.2005         Original published format: FI 20055257
FI2005000525627.05.2005         Original published format: FI 20055256
[2008/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2006125866
Date:30.11.2006
Language:EN
[2006/48]
Type: A1 Application with search report 
No.:EP1885749
Date:13.02.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 30.11.2006 takes the place of the publication of the European patent application.
[2008/07]
Type: B1 Patent specification 
No.:EP1885749
Date:23.08.2017
Language:EN
[2017/34]
Search report(s)International search report - published on:FI30.11.2006
(Supplementary) European search report - dispatched on:EP27.02.2009
ClassificationIPC:C07K14/51, A61K38/18, C12N15/70, C12N15/12
[2008/07]
CPC:
C07K14/51 (EP,US); A61P19/00 (EP); A61K38/00 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/34]
Former [2008/07]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:KNOCHENMORPHOGENETISCHES PROTEIN 3 UND OSTEOGENE VORRICHTUNGEN UND PHARMAZEUTISCHE PRODUKTE, DIE DIESES ENTHALTEN[2008/07]
English:BONE MORPHOGENETIC PROTEIN 3 AND OSTEOGENIC DEVICES AND PHARMACEUTICAL PRODUCTS CONTAINING THEREOF[2008/07]
French:PROTÉINE MORPHOGÉNÉTIQUE D'OS 3 ET DISPOSITIFS OSTÉOGÉNIQUES ET PRODUITS PHARMACEUTIQUES LES CONTENANT[2008/07]
Entry into regional phase11.12.2007National basic fee paid 
11.12.2007Search fee paid 
11.12.2007Designation fee(s) paid 
11.12.2007Examination fee paid 
Examination procedure11.12.2007Examination requested  [2008/07]
16.06.2009Despatch of a communication from the examining division (Time limit: M06)
16.12.2009Reply to a communication from the examining division
20.04.2010Despatch of a communication from the examining division (Time limit: M04)
16.08.2010Reply to a communication from the examining division
09.12.2010Despatch of a communication from the examining division (Time limit: M04)
31.03.2011Reply to a communication from the examining division
30.01.2013Despatch of a communication from the examining division (Time limit: M04)
07.06.2013Reply to a communication from the examining division
21.12.2016Communication of intention to grant the patent
18.04.2017Fee for grant paid
18.04.2017Fee for publishing/printing paid
18.04.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  16.06.2009
Opposition(s)24.05.2018No opposition filed within time limit [2018/31]
Fees paidRenewal fee
19.03.2008Renewal fee patent year 03
26.05.2009Renewal fee patent year 04
24.05.2010Renewal fee patent year 05
20.05.2011Renewal fee patent year 06
30.03.2012Renewal fee patent year 07
15.05.2013Renewal fee patent year 08
23.05.2014Renewal fee patent year 09
16.04.2015Renewal fee patent year 10
30.05.2016Renewal fee patent year 11
10.07.2017Renewal fee patent year 12
Penalty fee
Additional fee for renewal fee
31.05.201712   M06   Fee paid on   10.07.2017
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.05.2006
AT23.08.2017
CY23.08.2017
CZ23.08.2017
DK23.08.2017
EE23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
MC23.08.2017
NL23.08.2017
PL23.08.2017
PT23.08.2017
RO23.08.2017
SE23.08.2017
SI23.08.2017
SK23.08.2017
TR23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
[2020/31]
Former [2020/27]HU26.05.2006
AT23.08.2017
CZ23.08.2017
DK23.08.2017
EE23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
MC23.08.2017
NL23.08.2017
PL23.08.2017
PT23.08.2017
RO23.08.2017
SE23.08.2017
SI23.08.2017
SK23.08.2017
TR23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
Former [2020/16]AT23.08.2017
CZ23.08.2017
DK23.08.2017
EE23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
MC23.08.2017
NL23.08.2017
PL23.08.2017
RO23.08.2017
SE23.08.2017
SI23.08.2017
SK23.08.2017
TR23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
Former [2019/06]AT23.08.2017
CZ23.08.2017
DK23.08.2017
EE23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
MC23.08.2017
NL23.08.2017
PL23.08.2017
RO23.08.2017
SE23.08.2017
SI23.08.2017
SK23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
Former [2018/39]AT23.08.2017
CZ23.08.2017
DK23.08.2017
EE23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
NL23.08.2017
PL23.08.2017
RO23.08.2017
SE23.08.2017
SI23.08.2017
SK23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
Former [2018/23]AT23.08.2017
CZ23.08.2017
DK23.08.2017
EE23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
NL23.08.2017
PL23.08.2017
RO23.08.2017
SE23.08.2017
SK23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
Former [2018/21]AT23.08.2017
CZ23.08.2017
DK23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
NL23.08.2017
PL23.08.2017
SE23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
Former [2018/12]AT23.08.2017
FI23.08.2017
LT23.08.2017
LV23.08.2017
NL23.08.2017
PL23.08.2017
SE23.08.2017
BG23.11.2017
GR24.11.2017
IS23.12.2017
Former [2018/10]AT23.08.2017
FI23.08.2017
LT23.08.2017
NL23.08.2017
SE23.08.2017
Former [2018/09]FI23.08.2017
LT23.08.2017
NL23.08.2017
SE23.08.2017
Former [2018/08]FI23.08.2017
LT23.08.2017
NL23.08.2017
Former [2018/07]LT23.08.2017
Documents cited:Search[X]  - "1254007 MARC 7BOV Bos taurus cDNA 5', mRNA sequence.", EMBL, (20050311), Database accession no. DN515641, URL: EBI, XP002513027 [X] 7-9 * the whole document *
 [Y]  - KAPANEN A ET AL, "Bone morphogenetic protein 3b expressing reindeer antler.", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH JAN 2002, (200201), vol. 59, no. 1, ISSN 0021-9304, pages 78 - 83, XP002513026 [Y] 1-6,10-21 * abstract *

DOI:   http://dx.doi.org/10.1002/jbm.1219
 [Y]  - TAKAO M ET AL, "Identification of rat bone morphogenetic protein-3b (BMP-3b), a new member of BMP-3", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (19960101), vol. 219, no. 2, ISSN 0006-291X, pages 656 - 662, XP002351080 [Y] 1-6,10-21 * abstract *

DOI:   http://dx.doi.org/10.1006/bbrc.1996.0289
International search[A]US6204047  (LEE SE-JIN [US], et al);
 [A]WO2004061125  (MMI GENOMICS INC [US], et al)
 [A]  - "Rangifer tarandus tarandus bone morphogenetic protein 3b mRNA, partial cds", EMBL-EBI, (20001013), Database accession no. (AF300813), XP003004273
ExaminationWO9401557
    - RUPPERT R ET AL, "HUMAN BONE MORPHOGENETIC PROTEIN 2 CONTAINS A HEPARIN-BINDING SITE WHICH MODIFIES ITS BIOLOGICAL ACTIVITY", EUROPEAN JOURNAL OF BIOCHEMISTRY, BLACKWELL PUBLISHING, BERLIN, DE, (19960401), vol. 237, no. 1, doi:10.1111/J.1432-1033.1996.0295N.X, ISSN 0014-2956, pages 295 - 302, XP000891887

DOI:   http://dx.doi.org/10.1111/j.1432-1033.1996.0295n.x
    - HINO J ET AL, "CDNA CLONING AND GENOMIC STRUCTURE OF HUMAN BONE MORPHOGENETIC PROTEIN-3B (BMP-3B)", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (19960101), vol. 223, no. 2, doi:10.1006/BBRC.1996.0889, ISSN 0006-291X, pages 304 - 310, XP002947026

DOI:   http://dx.doi.org/10.1006/bbrc.1996.0889
    - HINO J ET AL, "Bone morphogenetic protein-3 FAMILY MEMBERS AND THEIR BIOLOGICAL FUNCTIONS", FRONTIERS IN BIOSCIENCE, FRONTIERS IN BIOSCIENCE, ALBERTSON, NY, US, (20040501), vol. 9, ISSN 1093-9946, pages 1520 - 1529, XP002351082
    - KANG Q ET AL, "Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.", GENE THERAPY SEP 2004, (200409), vol. 11, no. 17, ISSN 0969-7128, pages 1312 - 1320
    - CHEN D ET AL, "Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts.", CALCIFIED TISSUE INTERNATIONAL, (199703), vol. 60, no. 3, ISSN 0171-967X, pages 283 - 290
by applicantWO0243759
 US6245889
 US5399677
 WO9851354
 EP1131087
 WO9401557
    - FENG ET AL., BIOCHIM BIOPHYS ACTA, (1997), vol. 1350, pages 47 - 52
    - FENG ET AL., BIOCHIM BIOPHYS ACTA, (1995), vol. 1263, pages 163 - 168
    - KAPANEN ET AL., J BIOMED MAT RES, (2002), vol. 59, pages 78 - 83
    - THOMPSON, J.D.; HIGGINS, D.G.; GIBSON, T.J., NUCLEIC ACIDS RESEARCH, (1994), vol. 22, pages 4673 - 4680
    - REDDY AH, "Cartilage morphogenetic proteins: role in joint development, homoeostasis and regeneration", ANN RHEUM DIS, (2003), vol. 62, pages 73 - 78
    - MARSHALL R. URIST; J.J. CHANG; A. LIETZE; Y. K. HUO; A. G. BROWNELL; R. J. DELANGE, "Preparation and Bioassay of Bone Mor- phogenetic Protein and Polypeptide Fragments", METHODS ENZYMOL, (1987), vol. 146, pages 294 - 312
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.