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Extract from the Register of European Patents

EP About this file: EP1871165

EP1871165 - METHOD OF TREATING SCHIZOPHRENIA PRODROME [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  27.04.2018
Database last updated on 19.10.2024
FormerThe patent has been granted
Status updated on  19.05.2017
FormerGrant of patent is intended
Status updated on  23.01.2017
Most recent event   Tooltip26.06.2020Lapse of the patent in a contracting state
New state(s): CY
published on 29.07.2020  [2020/31]
Applicant(s)For all designated states
Yale University
2 Whitney Avenue
New Haven, CT 06511 / US
[2017/08]
Former [2008/01]For all designated states
Yale University Corporation
2 Whitney Avenue
New Haven Connecticut 06511 / US
Inventor(s)01 / WOODS, Scott, W.
99 Meadow St.
East Haven, Connecticut 06512 / US
 [2008/01]
Representative(s)Dall'Olio, Giancarlo
Invention S.r.l.
Via delle Armi 1
40137 Bologna / IT
[2017/25]
Former [2008/01]Dall'Olio, Giancarlo
Invention S.r.l. Via delle Armi, 1
40137 Bologna / IT
Application number, filing date06740849.211.04.2006
[2008/01]
WO2006US13444
Priority number, dateUS20050670600P11.04.2005         Original published format: US 670600 P
[2008/01]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2006110724
Date:19.10.2006
Language:EN
[2006/42]
Type: A2 Application without search report 
No.:EP1871165
Date:02.01.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 19.10.2006 takes the place of the publication of the European patent application.
[2008/01]
Type: B1 Patent specification 
No.:EP1871165
Date:21.06.2017
Language:EN
[2017/25]
Search report(s)International search report - published on:US22.03.2007
(Supplementary) European search report - dispatched on:EP22.09.2009
ClassificationIPC:A01N37/12, A01N37/44, A61K31/195, A61P25/18
[2009/43]
CPC:
A61K31/195 (EP,US); A61K31/198 (EP,US); A61P25/18 (EP);
A61P43/00 (EP)
Former IPC [2008/01]A01N37/12, A01N37/44, A61K31/195
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/25]
Former [2008/01]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL09.11.2007
BA09.11.2007
HR09.11.2007
MK09.11.2007
YU09.11.2007
TitleGerman:VERFAHREN ZUR BEHANDLUNG EINES PRODROMS VON SCHIZOPHRENIE[2008/01]
English:METHOD OF TREATING SCHIZOPHRENIA PRODROME[2008/01]
French:METHODE DE TRAITEMENT D'UN PRODROME SCHIZOPHRENIQUE[2008/01]
Entry into regional phase09.11.2007National basic fee paid 
09.11.2007Search fee paid 
09.11.2007Designation fee(s) paid 
09.11.2007Examination fee paid 
Examination procedure09.11.2007Amendment by applicant (claims and/or description)
09.11.2007Examination requested  [2008/01]
01.12.2009Despatch of a communication from the examining division (Time limit: M06)
20.07.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
17.09.2010Reply to a communication from the examining division
01.12.2011Despatch of a communication from the examining division (Time limit: M06)
06.06.2012Reply to a communication from the examining division
18.09.2013Despatch of a communication from the examining division (Time limit: M06)
14.03.2014Reply to a communication from the examining division
06.05.2015Despatch of a communication from the examining division (Time limit: M06)
28.10.2015Reply to a communication from the examining division
24.01.2017Communication of intention to grant the patent
09.05.2017Fee for grant paid
09.05.2017Fee for publishing/printing paid
09.05.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  01.12.2009
Opposition(s)22.03.2018No opposition filed within time limit [2018/22]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
15.09.2010Request for further processing filed
15.09.2010Full payment received (date of receipt of payment)
Fees paidRenewal fee
22.04.2008Renewal fee patent year 03
21.04.2009Renewal fee patent year 04
26.03.2010Renewal fee patent year 05
25.04.2011Renewal fee patent year 06
25.04.2012Renewal fee patent year 07
29.04.2013Renewal fee patent year 08
28.04.2014Renewal fee patent year 09
27.08.2015Renewal fee patent year 10
27.04.2016Renewal fee patent year 11
27.04.2017Renewal fee patent year 12
Penalty fee
Additional fee for renewal fee
30.04.201510   M06   Fee paid on   27.08.2015
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Lapses during opposition  TooltipHU11.04.2006
AT21.06.2017
CY21.06.2017
CZ21.06.2017
DK21.06.2017
EE21.06.2017
ES21.06.2017
FI21.06.2017
IT21.06.2017
LT21.06.2017
LV21.06.2017
MC21.06.2017
NL21.06.2017
PL21.06.2017
PT21.06.2017
RO21.06.2017
SE21.06.2017
SI21.06.2017
SK21.06.2017
TR21.06.2017
BG21.09.2017
GR22.09.2017
IS21.10.2017
[2020/31]
Former [2020/27]HU11.04.2006
AT21.06.2017
CZ21.06.2017
DK21.06.2017
EE21.06.2017
ES21.06.2017
FI21.06.2017
IT21.06.2017
LT21.06.2017
LV21.06.2017
MC21.06.2017
NL21.06.2017
PL21.06.2017
PT21.06.2017
RO21.06.2017
SE21.06.2017
SI21.06.2017
SK21.06.2017
TR21.06.2017
BG21.09.2017
GR22.09.2017
IS21.10.2017
Former [2020/15]AT21.06.2017
CZ21.06.2017
DK21.06.2017
EE21.06.2017
ES21.06.2017
FI21.06.2017
IT21.06.2017
LT21.06.2017
LV21.06.2017
MC21.06.2017
NL21.06.2017
PL21.06.2017
RO21.06.2017
SE21.06.2017
SI21.06.2017
SK21.06.2017
TR21.06.2017
BG21.09.2017
GR22.09.2017
IS21.10.2017
Former [2018/52]AT21.06.2017
CZ21.06.2017
DK21.06.2017
EE21.06.2017
ES21.06.2017
FI21.06.2017
IT21.06.2017
LT21.06.2017
LV21.06.2017
MC21.06.2017
NL21.06.2017
PL21.06.2017
RO21.06.2017
SE21.06.2017
SI21.06.2017
SK21.06.2017
BG21.09.2017
GR22.09.2017
IS21.10.2017
Former [2018/39]AT21.06.2017
CZ21.06.2017
DK21.06.2017
EE21.06.2017
ES21.06.2017
FI21.06.2017
IT21.06.2017
LT21.06.2017
LV21.06.2017
NL21.06.2017
PL21.06.2017
RO21.06.2017
SE21.06.2017
SI21.06.2017
SK21.06.2017
BG21.09.2017
GR22.09.2017
IS21.10.2017
Former [2018/21]AT21.06.2017
CZ21.06.2017
DK21.06.2017
EE21.06.2017
ES21.06.2017
FI21.06.2017
IT21.06.2017
LT21.06.2017
LV21.06.2017
NL21.06.2017
PL21.06.2017
RO21.06.2017
SE21.06.2017
SK21.06.2017
BG21.09.2017
GR22.09.2017
IS21.10.2017
Former [2018/11]AT21.06.2017
CZ21.06.2017
EE21.06.2017
ES21.06.2017
FI21.06.2017
IT21.06.2017
LT21.06.2017
LV21.06.2017
NL21.06.2017
PL21.06.2017
RO21.06.2017
SE21.06.2017
SK21.06.2017
BG21.09.2017
GR22.09.2017
IS21.10.2017
Former [2018/10]AT21.06.2017
CZ21.06.2017
EE21.06.2017
FI21.06.2017
LT21.06.2017
LV21.06.2017
NL21.06.2017
RO21.06.2017
SE21.06.2017
SK21.06.2017
BG21.09.2017
GR22.09.2017
Former [2018/09]EE21.06.2017
FI21.06.2017
LT21.06.2017
LV21.06.2017
NL21.06.2017
SE21.06.2017
BG21.09.2017
GR22.09.2017
Former [2017/52]FI21.06.2017
LT21.06.2017
LV21.06.2017
NL21.06.2017
SE21.06.2017
BG21.09.2017
GR22.09.2017
Former [2017/50]FI21.06.2017
LT21.06.2017
LV21.06.2017
SE21.06.2017
BG21.09.2017
GR22.09.2017
Former [2017/49]FI21.06.2017
LT21.06.2017
GR22.09.2017
Documents cited:Search[X]WO2005023261  (HOFFMANN LA ROCHE [CH], et al) [X] 1-18 * example 57 *;
 [PX]WO2005040166  (HOFFMANN LA ROCHE [CH], et al) [PX] 1-18 * example 85 *;
 [PX]WO2005058317  (GLAXO GROUP LTD [GB], et al) [PX] 1-18 * example 10 *;
 [PX]WO2005058882  (GLAXO GROUP LTD [GB], et al) [PX] 1-18 * example 4 *;
 [PX]WO2005058885  (GLAXO GROUP LTD [GB], et al) [PX] 1-18* example 37 *;
 [PX]WO2005087708  (LUNDBECK & CO AS H [DK], et al) [PX] 1-18 * claim 1 *;
 [X]  - JAVITT DANIEL C, "Glycine modulators in schizophrenia", CURRENT OPINION IN INVESTIGATIONAL DRUGS, PHARMAPRESS, US, (20020701), vol. 3, no. 7, ISSN 1472-4472, pages 1067 - 1072, XP009122695 [X] 1-18 * see "Gylcine", "D-Serine", "D-Cycloserine" and "Glycine transport inhibitors". *
 [X]  - HERESCO-LEVY U, "N-methyl-D-aspartate (NMDA) receptor-based treatment approaches in schizophrenia: The first decade", INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, CAMBRIDGE UNIVERSITY PRESS, CAMBRIDGE, GB, (20000101), vol. 3, no. 3, ISSN 1461-1457, pages 243 - 258, XP009108956 [X] 1-18 * page 252, column RIGHT, paragraph 3; tables 1,3 *

DOI:   http://dx.doi.org/10.1017/S1461145700001978
 [X]  - TSAI G ET AL, "GLYCINE TRASPORTER I INHIBITOR, N-METHYLGLYCINE (SARCOSINE), ADDED TO ANTIPSYCHOTICS FOR THE TREATMENT OF SCHIZOPHRENIA", BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE, NEW YORK, NY, US, (20040301), vol. 55, no. 5, ISSN 0006-3223, pages 452 - 456, XP008052565 [X] 1-18 * table 2 *

DOI:   http://dx.doi.org/10.1016/j.biopsych.2003.09.012
 [X]  - HERESCO-LEVY U ET AL, "Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia", ARCHIVES OF GENERAL PSYCHIATRY, XX, XX, (19990101), vol. 56, no. 1, pages 29 - 36, XP009028275 [X] 1-18 * abstract *

DOI:   http://dx.doi.org/10.1001/archpsyc.56.1.29
International search[Y]US2002013364  (JAVITT DANIEL C [US])
Examination   - WOODS ET AL, "The prodromal Patient. Both symptomatic and at risk", CNS SPECTRUM, (20010301), vol. 6, no. 3, pages 223 - 232
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.