blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP1891072

EP1891072 - Substituted 7,8-Dihydro-1H-pyrimido[4,5-b]diazepin-4-amines as kinase inhibitors [Right-click to bookmark this link]
Former [2008/09]SUBSTITUTED 7, 8-DIHYDRO-1H-PYRIMIDO[4,5-B][1,4] DIAZEPIN-4-AMINES ASKINASE INHIBITORS
[2011/26]
StatusNo opposition filed within time limit
Status updated on  16.11.2012
Database last updated on 15.06.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
ABBOTT LABORATORIES
100 Abbott Park Road
Abbott Park, IL 60064-3500 / US
[N/P]
Former [2008/36]For all designated states
ABBOTT LABORATORIES
CHAD 0377/AP6A-1 100 Abbott Park Road
Abbott Park IL 60064-3500 / US
Former [2008/09]For all designated states
ABBOTT LABORATORIES
Dept. 377 Bldg. AP6A-1, 100 Abbott Park Road
Abbott Park, Illinois 60064-6008 / US
Inventor(s)01 / GRACIAS, Vijaya, J.
335 Hummingbird Lane
Lindenhurst, IL 60046 / US
02 / ABAD-ZAPATERO, Celerino
765 Greenview Pl
Lake Forest, IL 60045 / US
03 / DJURIC, Stevan, W.
621 Paddock Ln
Libertyville, IL 60048 / US
04 / JI, Zhiqin
1103 Tamarack Ln
Libertyville, IL 60048 / US
05 / MICHAELIDES, Michael, R.
4452 W Gavin Ln
Libertyville, IL 60048 / US
06 / STEWART, Kent, D.
4715 Kings Way N
Gurnee, IL 60031 / US
07 / ZANZE, Irini
1817 S. Waxwing Lane
Libertyville, IL 60048 / US
 [2008/09]
Representative(s)Modiano, Micaela Nadia
Modiano Josif Pisanty & Staub Ltd
Thierschstrasse 11
80538 München / DE
[N/P]
Former [2012/02]Modiano, Micaela Nadia
Modiano Josif Pisanty & Staub Ltd Thierschstrasse 11
80538 München / DE
Former [2009/36]Modiano, Micaela Nadia
Modiano Josif Pisanty & Staub Ltd Thierschstrasse 11
80538 München / DE
Former [2008/09]Modiano, Micaela Nadia
Modiano Josif Pisanty & Staub Ltd Thierschstrasse 11
80538 München / DE
Application number, filing date06759877.116.05.2006
[2008/09]
WO2006US18796
Priority number, dateUS20050682290P18.05.2005         Original published format: US 682290 P
[2008/09]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2006124813
Date:23.11.2006
Language:EN
[2006/47]
Type: A2 Application without search report 
No.:EP1891072
Date:27.02.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 23.11.2006 takes the place of the publication of the European patent application.
[2008/09]
Type: B1 Patent specification 
No.:EP1891072
Date:11.01.2012
Language:EN
[2012/02]
Search report(s)International search report - published on:EP12.04.2007
ClassificationIPC:C07D487/04, // A61K31/551
[2011/26]
CPC:
C07D487/04 (EP,US); A61P1/04 (EP); A61P11/00 (EP);
A61P17/06 (EP); A61P19/02 (EP); A61P21/04 (EP);
A61P25/00 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P35/00 (EP); A61P35/02 (EP); A61P35/04 (EP);
A61P37/00 (EP); A61P37/02 (EP); A61P37/06 (EP);
A61P43/00 (EP); A61P9/12 (EP) (-)
Former IPC [2008/09]C07D487/04
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/09]
Extension statesAL17.12.2007
BA17.12.2007
HR17.12.2007
MK17.12.2007
YU17.12.2007
TitleGerman:Substituierte 7,8-Dihydro-1H-pyrimido[4,5-b]diazepin-4-amine als Kinase Inhibitoren[2011/26]
English:Substituted 7,8-Dihydro-1H-pyrimido[4,5-b]diazepin-4-amines as kinase inhibitors[2011/26]
French:7,8-Dihydro-1H-pyrimido[4,5-b]diazepin-4-amines substiuées en tant qu'inhibiteurs de kinase[2011/26]
Former [2008/09]SUBSTITUIERTE 7,8-DIHYDRO-1H-PYRIMIDO[4,5-B][1,4]DIAZEPIN-4-AMINE SIND NEUE KINASEINHIBITOREN
Former [2008/09]SUBSTITUTED 7, 8-DIHYDRO-1H-PYRIMIDO[4,5-B][1,4] DIAZEPIN-4-AMINES ASKINASE INHIBITORS
Former [2008/09]7, 8-DIHYDRO-1H-PYRIMIDO[4,5-B][1,4]DIAZEPINE-4-AMINES SUBSTITUEES, EN TANT QU'INHIBITEURS DE KINASE
Entry into regional phase17.12.2007National basic fee paid 
17.12.2007Designation fee(s) paid 
17.12.2007Examination fee paid 
Examination procedure17.12.2007Amendment by applicant (claims and/or description)
17.12.2007Examination requested  [2008/09]
09.04.2008Despatch of a communication from the examining division (Time limit: M04)
19.08.2008Reply to a communication from the examining division
27.08.2008Despatch of a communication from the examining division (Time limit: M02)
21.10.2008Reply to a communication from the examining division
20.07.2011Communication of intention to grant the patent
29.11.2011Fee for grant paid
29.11.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.04.2008
Opposition(s)12.10.2012No opposition filed within time limit [2012/51]
Fees paidRenewal fee
18.03.2008Renewal fee patent year 03
07.05.2009Renewal fee patent year 04
31.03.2010Renewal fee patent year 05
10.05.2011Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU16.05.2006
AT11.01.2012
BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
SK11.01.2012
TR11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
IE16.05.2012
LU16.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
[2014/34]
Former [2014/27]AT11.01.2012
BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
SK11.01.2012
TR11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
IE16.05.2012
LU16.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2014/21]AT11.01.2012
BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
SK11.01.2012
TR11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
IE16.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/20]AT11.01.2012
BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
SK11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
IE16.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/07]AT11.01.2012
BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
SK11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/03]BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
SK11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
MC31.05.2012
Former [2012/50]BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
SK11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
Former [2012/49]BE11.01.2012
CY11.01.2012
CZ11.01.2012
DK11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
RO11.01.2012
SE11.01.2012
SI11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
Former [2012/48]BE11.01.2012
CY11.01.2012
EE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
SE11.01.2012
SI11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
Former [2012/41]BE11.01.2012
CY11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
SI11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
Former [2012/39]BE11.01.2012
FI11.01.2012
LT11.01.2012
LV11.01.2012
NL11.01.2012
PL11.01.2012
SI11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
Former [2012/37]BE11.01.2012
FI11.01.2012
LT11.01.2012
NL11.01.2012
PL11.01.2012
SI11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
PT11.05.2012
Former [2012/36]BE11.01.2012
LT11.01.2012
NL11.01.2012
SI11.01.2012
BG11.04.2012
GR12.04.2012
IS11.05.2012
Former [2012/35]BE11.01.2012
LT11.01.2012
NL11.01.2012
SI11.01.2012
BG11.04.2012
IS11.05.2012
Former [2012/34]BE11.01.2012
LT11.01.2012
SI11.01.2012
IS11.05.2012
Former [2012/33]BE11.01.2012
LT11.01.2012
SI11.01.2012
Former [2012/25]SI11.01.2012
Cited inInternational search[Y]WO0119828  (BASF AG [DE], et al) [Y] 1-10 * abstract * * in particular page 95, lines 9-12 * * page 2, line 14 - page 9, line 7 * * page 55, line 29 - page 66, line 6 *;
 [Y]WO2004056830  (PFIZER PROD INC [US], et al) [Y] 1-10 * abstract * * page 37 - page 38; compounds 1B,9 * * page 1, line 27 - page 3, line 37 * * page 53, line 18 - page 57, line 23 *;
 [A]  - BRAULIO INSUASTY O., HENRY INSUASTY I. JAIRO QUIROGA P., CLAUDIO SAITZ AND CAROLINA JULLIAN, "Reaction of 4,5,6-Triaminopyrimidine and 2,4,5,6-Tetraaminopyrimidine with 3-Dimethylaminopropriophenones. Synthesis of new 4-Aryl-2,3-dihydropyrimido[4,5-b][1,4]diazepines", JOURNAL OF HETEROCYCLIC CHEMISTRY, (2000), vol. 37, pages 401 - 403, XP002417917 [A] 1-10 * the whole document * * in particular scheme 1, compounds 3a-3i *

DOI:   http://dx.doi.org/10.1002/jhet.5570370228
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.