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Extract from the Register of European Patents

EP About this file: EP1919507

EP1919507 - NANOPARTICLES COMPRISING ANTIBACTERIAL LIGANDS [Right-click to bookmark this link]
Status	The application has been refused Status updated on 12.07.2019 Database last updated on 12.07.2024
Former	Examination is in progress Status updated on 06.10.2017
Most recent event Tooltip	12.07.2019	Refusal of application	published on 14.08.2019 [2019/33]
Applicant(s)	For all designated states MIDATECH LTD 4 & 5 Dunmore Court Wootton Road Abingdon Oxford Oxfordshire, OX136BH / GB
	[2013/49]
Former [2008/20]	For all designated states Rademacher, Thomas William 4 & 5 Dunmore Court Wootton Road Abingdon, Oxford Oxfordshire OX13 6BH / GB
	For all designated states Bradman, Godfrey 4 & 5 Dunmore Court Wootton Road Abingdon, Oxford Oxfordshire OX13 6BH / GB
	For all designated states Penades Ullate, Soledad Calle Serano E-113 28006 Madrid / ES
	For all designated states Ojeda Martinez de Castilla, Rafael Calle Serano, E-113 28006 Madrid / ES
Inventor(s)	01 / Radmacher, Thomas Wiliam 4& 5 Dunmore Court, Wootton Road Abingdon, Oxford, Oxfordshire OX13 6BH / GB
	02 / Bradman, Godfrey 4 & 5 Dunmore Court, Wootton Road Abingdon, Oxford, Oxfordshire OX13 6BH / GB
	03 / Penades Ullate, Soledad c/o Consejo Superior De Investigaciones Cientificas Calle Serano E-113 28006 Madrid / ES
	04 / Ojeda Martinez, DeCastilla c/o Consejo Superior De Investigaciones Cientificas Calle Serano E-113 28006 Madrid / ES
	[2013/49]
Former [2008/20]	01 / see applicant ...
Representative(s)	Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB
	[N/P]
Former [2008/20]	Kiddle, Simon John, et al Mewburn Ellis LLP York House, 23 Kingsway London WC2B 6HP / GB
Application number, filing date	06765226.3	04.08.2006
	[2008/20]
	WO2006GB02923
Priority number, date	GB20050016070	04.08.2005 Original published format: GB 0516070
	US20050705175P	04.08.2005 Original published format: US 705175 P
	[2008/20]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2007015105
	Date:	08.02.2007
	Language:	EN
	[2007/06]
	Type:	A2 Application without search report
	No.:	EP1919507
	Date:	14.05.2008
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 08.02.2007 takes the place of the publication of the European patent application.
	[2008/20]
Search report(s)	International search report - published on:	EP	01.11.2007
Classification	IPC:	A61K47/48, A61K41/00, A61P31/04, A61P31/06	[2008/20]
	CPC:	A61K47/552 (EP,US); A61K41/0052 (EP,US); A61K47/6923 (EP,US); A61K47/6929 (EP,US); A61P31/04 (EP); A61P31/06 (EP); (+) B82Y5/00 (EP,US); Y02A50/30 (EP); Y10S977/773 (EP,US); Y10S977/906 (EP,US) (-)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2008/20]
Extension states	AL	Not yet paid
	BA	Not yet paid
	HR	Not yet paid
	MK	Not yet paid
	RS	Not yet paid
Title	German:	NANOTEILCHEN MIT ANTIBAKTERIELLEN LIGANDEN	[2008/20]
	English:	NANOPARTICLES COMPRISING ANTIBACTERIAL LIGANDS	[2008/20]
	French:	NANOPARTICULES COMPRENANT DES LIGANDS ANTIBACTERIENS	[2008/20]
Entry into regional phase	22.02.2008	National basic fee paid
	22.02.2008	Designation fee(s) paid
	22.02.2008	Examination fee paid
Examination procedure	15.02.2008	Amendment by applicant (claims and/or description)
	22.02.2008	Examination requested [2008/20]
	07.11.2013	Despatch of a communication from the examining division (Time limit: M06)
	24.03.2014	Reply to a communication from the examining division
	27.09.2017	Despatch of a communication from the examining division (Time limit: M06)
	09.04.2018	Reply to a communication from the examining division
	24.01.2019	Cancellation of oral proceeding that was planned for 14.02.2019
	14.02.2019	Date of oral proceedings (cancelled)
	21.03.2019	Despatch of communication that the application is refused, reason: substantive examination [2019/33]
	31.03.2019	Application refused, date of legal effect [2019/33]
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 07.11.2013
Fees paid	Renewal fee
	21.08.2008	Renewal fee patent year 03
	05.01.2010	Renewal fee patent year 04
	20.08.2010	Renewal fee patent year 05
	22.08.2011	Renewal fee patent year 06
	23.08.2012	Renewal fee patent year 07
	30.08.2013	Renewal fee patent year 08
	29.08.2014	Renewal fee patent year 09
	24.08.2015	Renewal fee patent year 10
	24.08.2016	Renewal fee patent year 11
	25.08.2017	Renewal fee patent year 12
	10.08.2018	Renewal fee patent year 13
	Penalty fee
	Additional fee for renewal fee
	31.08.2009	04 M06 Fee paid on 05.01.2010
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[DX]WO0232404 (CONSEJO SUPERIOR INVESTIGACION [ES], et al) [DX] 1,4-7,9,10,14-32,34 * page 8, line 30 - page 9, line 5 * * page 12, line 25 - page 13, line 14 * * page 17, lines 11-16 * * claims 1-24,26,27,33-35 * * figures 1,2 *;
		[X]WO03022999 (GENOMIC PROFILING SYSTEMS INC [US]) [X] 1-4,9,15,18-22,24,30 * page 24, lines 13-21 * * page 71, lines 11-14 *;
		[X]WO2004102196 (CHENGDU KUACHANG MEDICAL IND L [CN], et al) [X] 1-4,6,7,9,18-22,24,30 * abstract *;
		[DXA]WO2004108165 (CONSEJO SUPERIOR INVESTIGACION [ES], et al) [DX] 1,2,4-7,9-34,36 * page 19, lines 5-13 * * page 24, lines 26-34 * * page 29, lines 28-32 * * page 46, line 33 * * examples 1-3 * * claims 1-25,27-32,52-57 * [A] 37-39;
		[X]WO2005044365 (TRITON BIOSYSTEMS INC [US], et al) [X] 1,2,4,6,8,9,15,16,18-25,30-36,38,39 * page 4, line 29 - page 5, line 5 * * page 6, lines 8-12 * * page 8, lines 26-28 * * page 10, lines 19-26 * * page 14, lines 1-3,12,13 * * page 16, line 27 - page 17, line 5 * * page 19, line 26 - page 20, line 12 * * page 39, lines 16-18 *;
		[PX]EP1624306 (CHENGDU KUACHANG MEDICAL IND L [CN], et al) [PX] 1-4,6,7,9,18-22,24,30 * claims 65,66 * * paragraph [0017] *;
		[PA]WO2006037979 (MIDATECH LTD [GB], et al) [PA] 1,2,4-36 * figure 8/11 ** claim - *;
		[E]WO2006108405 (MAGFORCE NANOTECHNOLOGIES AG [DE], et al) [E] 1-4,6,7,9,15-22,24,25,30-34,36,38,39 * page 3, line 25 - page 4, line 10 * * page 5, lines 4-6 * * page 8, line 6 - line 20 * * page 17, lines 15,16 * * page 18, lines 20-22 * * example 1 * * claims 1,7-14 *;
		[X] - LIN YA-SHIUAN ET AL, "Affinity capture using vancomycin-bound magnetic nanoparticles for the MALDI-MS analysis of bacteria.", ANALYTICAL CHEMISTRY 15 MAR 2005, (20050315), vol. 77, no. 6, ISSN 0003-2700, pages 1753 - 1760, XP002446940 [X] 1-4,6,8,9,15,18-22,24,30 * page 1753, column 2, paragraph 2 - page 1754, column 1, paragraph 2 * * scheme 1 * * page 1754, column 2 * DOI: http://dx.doi.org/10.1021/ac048990k
		[X] - GU HONGWEI ET AL, "Using biofunctional magnetic nanoparticles to capture gram-negative bacteria at an ultra-low concentration.", CHEMICAL COMMUNICATIONS (CAMBRIDGE, ENGLAND) 7 AUG 2003, (20030807), no. 15, ISSN 1359-7345, pages 1966 - 1967, XP002446941 [X] 1-4,6,9,11-13,15,16,18-22,24,30 * abstract * * scheme 1 * * page 1966, column 2, paragraph 1 * DOI: http://dx.doi.org/10.1039/b305421g
		[A] - SUN S ET AL, "Monodisperse FePt nanoparticles and ferromagnetic FePt nanocrystal superlattices", SCIENCE 17 MAR 2000 UNITED STATES, (20000317), vol. 287, no. 5460, ISSN 0036-8075, pages 1989 - 1992, XP002446942 [A] 11-13 * page 1989, column 2, paragraph LAST - column 3, paragraph 1 * DOI: http://dx.doi.org/10.1126/science.287.5460.1989
		[X] - GU, HONGWEI ET AL, "Presenting vancomycin on nanoparticles to enhance antimicrobial activities", NANO LETTERS , 3(9), 1261-1263 CODEN: NALEFD; ISSN: 1530-6984, (2003), XP002446943 [X] 1,3,4,6,9,14-16,18,21,22,24,30 * page 1261, column 2, paragraph 2 * * scheme 1 * DOI: http://dx.doi.org/10.1021/nl034396z
		[X] - TOM RENJIS T ET AL, "Ciprofloxacin-protected gold nanoparticles.", LANGMUIR : THE ACS JOURNAL OF SURFACES AND COLLOIDS 2 MAR 2004, (20040302), vol. 20, no. 5, ISSN 0743-7463, pages 1909 - 1914, XP002446944 [X] 1,3,4,6,9,14,18,19,21,22,24,25,31,32,34 * abstract * * page 1909, column 2, paragraph 2 - page 1910, column 1, paragraph 1 * * page 1910, column 1, paragraph LAST - column 2, paragraph 1 * DOI: http://dx.doi.org/10.1021/la0358567
		[X] - RAMAKRISHNAN R ET AL, "SENSITIVE ASSAY FOR IDENTIFICATION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS, BASED ON DIRECT DETECTION OF GENOMIC DNA BY USE OF GOLD NANOPARTICLE PROBES", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY, WASHINGTON, DC, US, (200410), vol. 50, no. 10, ISSN 0009-9147, pages 1949 - 1952, XP001207433 [X] 1,4,9,10,14-18,22,24,30 * figure 1 * DOI: http://dx.doi.org/10.1373/clinchem.2004.036723
		[A] - STORHOFF J J ET AL, "One-pot colorimetric differentiation of polynucleotides with single base imperfection using gold nanoparticle probes", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, (19980311), vol. 120, ISSN 0002-7863, pages 1959 - 1964, XP002113277 [A] 15-17 * page 1960, column 1, paragraph 4 - column 2, paragraph 3 * DOI: http://dx.doi.org/10.1021/ja972332i
		[X] - JENSEN KATIE L ET AL, "Use of gold nanoparticles to identify targets of membrane-active steroid antiobiotics", ABSTRACTS OF PAPERS AMERICAN CHEMICAL SOCIETY, & 223RD NATIONAL MEETING OF THE AMERICAN CHEMICAL SOCIETY; ORLANDO, FL, USA; APRIL 07-11, 2002, (2002), vol. 223, no. 1-2, ISSN 0065-7727, page CHED 855, XP002446945 [X] 1,4,9,14,18,22,24 * abstract *
		[X] - LIN C-C ET AL, "Selective binding of mannose-encapsulated gold nanoparticles to type 1 pili in Escherichia coli", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 10 APR 2002 UNITED STATES, (20020410), vol. 124, no. 14, ISSN 0002-7863, pages 3508 - 3509, XP002446946 [X] 1,4,6,9,14-18,21-24,26-30 * scheme 1 * * page 3508, column 2 * DOI: http://dx.doi.org/10.1021/ja0200903
		[ ] - LIN C-C ET AL, "Detailed experimental procedures, stability measurements, competition assays and data analyses for UV-vis, TEM, XPS, IR and NMR spectroscopy", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, SUPPLEMENTAL MATERIALS, United State, (20020410), vol. 124, no. 14, pages 1 - 7, XP002448131 [ ] * page 3: synthesis of m-AuNP,1 * DOI: http://dx.doi.org/10.1021/ja015113c
		[DX] - JESUS M DE LA FUENTE ET AL, "Understanding carbohydrate-carbohydrate Interactions by means of glyconanotechnology", GLYCOCONJUGATE JOURNAL, KLUWER ACADEMIC PUBLISHERS, BO, (20040101), vol. 21, no. 3-4, ISSN 1573-4986, pages 149 - 163, XP019207009 [DX] 1,4-7,9,14-16,18,19,21-24,26,27,29,30 * page 155, section "Gold glycanoparticles" * * figures 8,13 * * page 161, column 1 * DOI: http://dx.doi.org/10.1023/B:GLYC.0000044846.80014.cb
		[XA] - ZHAROV VLADIMIR P ET AL, "Photothermal guidance for selective photothermolysis with nanoparticles", PROC SPIE INT SOC OPT ENG; PROCEEDINGS OF SPIE - THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING; PROGRESS IN BIOMEDICAL OPTICS AND IMAGING - LASER INTERACTION WITH TISSUE AND CELLS 2004, (2004), vol. 5319, pages 291 - 300, XP002446947 [X] 1,4,9,14,15,18,21,22,24,25,31,32,34,35 * abstract * * pages 297-298, section 4 * [A] 37 DOI: http://dx.doi.org/10.1117/12.532011
		[A] - NARUSE YUJIRO, "Theoretical concept of physical antibiotics using nanoparticles", JPN J APPL PHYS PART 1 REGUL PAP SHORT NOTE REV PAP; JAPANESE JOURNAL OF APPLIED PHYSICS, PART 1: REGULAR PAPERS AND SHORT NOTES AND REVIEW PAPERS MAY 2005, (200505), vol. 44, no. 5 A, pages 3330 - 3332, XP002446948 [A] 1,24,25,31-39 * abstract * DOI: http://dx.doi.org/10.1143/JJAP.44.3330
		[PX] - NIRMALA GRACE A ET AL, "Antibacterial efficacy of aminoglycosidic antibiotics protected gold nanoparticles-A brief study", COLLOIDS AND SURFACES A: PHYSICOCHEMICAL AND ENGINEERING ASPECTS 05 APR 2007 NETHERLANDS, (20070405), vol. 297, no. 1-3, ISSN 0927-7757, pages 63 - 70, XP002446949 [PX] 1,3,4,9,14,18,21,22,24,25,31,32,34,35 * available online 13 October 2006 * * abstract * * page 64, column 2, section 2.3 * * page 70, column 1, paragraph LAST * DOI: http://dx.doi.org/10.1016/j.colsurfa.2006.10.024

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