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Extract from the Register of European Patents

EP About this file: EP1909810

EP1909810 - INHIBITORS OF SERINE PROTEASE ACTIVITY AND THEIR USE IN METHODS AND COMPOSITIONS FOR TREATMENT OF GRAFT REJECTION AND PROMOTION OF GRAFT SURVIVAL [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  21.07.2017
Database last updated on 16.09.2024
Most recent event   Tooltip27.10.2017Lapse of the patent in a contracting state
New state(s): BE		published on 29.11.2017  [2017/48]
Applicant(s)For all designated states
The Regents of the University of Colorado
4001 Discovery Drive, Suite 390
Campus Box 588 UCB
Boulder, CO 80309 / US
[2014/38]
Former [2014/21]For all designated states
The Regents of the University of Colorado
4001 Discovery Drive, Suite 390
Campus Box 588 Sys
Boulder, CO 80309 / US
Former [2009/36]For all designated states
The Board of Regents of the University of Colorado
4001 Discovery Drive, Suite 390, Campus Box 588 SYS
Boulder, CO 80309 / US
Former [2008/16]For all designated states
The Regents of the University of Colorado
4001 Discovery Drive, Suite 390, Campus Box 588 SYS
Boulder, CO 80309-0588 / US
Inventor(s)01 / SHAPIRO, Leland
3070 Ash Street
Denver, CO 80207 / US
02 / LEWIS, Eli, C.
1059 Fillmore Street
Denver, CO 80206 / US
03 / DINARELLO, Charles, A.
333 15th Street
Boulder, CO 80302 / US
 [2008/16]
Representative(s)Bohmann, Armin K., et al
Bohmann
Anwaltssozietät
Nymphenburger Straße 1
80335 München / DE
[2014/38]
Former [2008/16]Bohmann, Armin K., et al
Bohmann & Loosen Anwaltssozietät Nymphenburger Strasse 1
80335 München / DE
Application number, filing date06772664.607.06.2006
[2008/16]
WO2006US22436
Priority number, dateUS20050687850P07.06.2005         Original published format: US 687850 P
[2008/16]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2006133403
Date:14.12.2006
Language:EN
[2006/50]
Type: A2 Application without search report 
No.:EP1909810
Date:16.04.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 14.12.2006 takes the place of the publication of the European patent application.
[2008/16]
Type: B1 Patent specification 
No.:EP1909810
Date:17.09.2014
Language:EN
[2014/38]
Type: B2 New European patent specification 
No.:EP1909810
Date:23.08.2017
Language:EN
[2017/34]
Search report(s)International search report - published on:US03.05.2007
(Supplementary) European search report - dispatched on:EP22.09.2009
ClassificationIPC:A61K38/00, A61K38/16, A61K38/48
[2008/16]
CPC:
A61K38/57 (EP,US); A61K35/39 (EP,US); A61K38/191 (EP,US);
A61K38/217 (EP,US); A61K45/06 (EP,US); A61P1/18 (EP);
A61P17/02 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P37/02 (EP); A61P37/06 (EP); C07K16/40 (EP,US);
A61K2039/505 (EP,US) (-)
C-Set:
A61K35/39, A61K2300/00 (US,EP);
A61K38/191, A61K2300/00 (EP,US);
A61K38/57, A61K2300/00 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2017/34]
Former [2008/16]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:HEMMER DER SERINPROTEASE-AKTIVITÄT UND IHRE VERWENDUNG IN VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON TRANSPLANTAT-ABSTOSSUNG UND FÖRDERUNG DES TRANSPLANTAT-ÜBERLEBENS[2008/16]
English:INHIBITORS OF SERINE PROTEASE ACTIVITY AND THEIR USE IN METHODS AND COMPOSITIONS FOR TREATMENT OF GRAFT REJECTION AND PROMOTION OF GRAFT SURVIVAL[2008/16]
French:INHIBITEURS DE L'ACTIVITE SERINE PROTEASE ET LEUR UTILISATION DANS DES PROCEDES ET COMPOSITIONS POUR LE TRAITEMENT DU REJET DU GREFFON ET LA PROMOTION DE LA SURVIE DU GREFFON[2008/16]
Entry into regional phase07.01.2008National basic fee paid 
07.01.2008Search fee paid 
07.01.2008Designation fee(s) paid 
07.01.2008Examination fee paid 
Examination procedure07.01.2008Examination requested  [2008/16]
19.04.2010Amendment by applicant (claims and/or description)
15.06.2010Despatch of a communication from the examining division (Time limit: M06)
27.12.2010Reply to a communication from the examining division
22.02.2011Despatch of a communication from the examining division (Time limit: M06)
18.07.2011Reply to a communication from the examining division
22.09.2011Despatch of a communication from the examining division (Time limit: M06)
08.05.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
12.07.2012Reply to a communication from the examining division
22.08.2012Despatch of a communication from the examining division (Time limit: M06)
28.02.2013Reply to a communication from the examining division
15.03.2013Despatch of a communication from the examining division (Time limit: M04)
13.05.2013Reply to a communication from the examining division
10.06.2013Despatch of a communication from the examining division (Time limit: M04)
21.10.2013Reply to a communication from the examining division
28.04.2014Communication of intention to grant the patent
06.08.2014Fee for grant paid
06.08.2014Fee for publishing/printing paid
06.08.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.06.2010
Opposition(s)Opponent(s)01  17.06.2015  23.06.2015  ADMISSIBLE
BALEMA GmbH
Schlossergasse 28
77694 Kehl / DE
Opponent's representative
Straus, Alexander, et al, et al
Patentanwälte
Becker, Kurig, Straus
Bavariastrasse 7
80336 München / DE
 [2016/49]
Former [2015/30]
Opponent(s)01  17.06.2015   
BALEMA GmbH
Schlossergasse 28
77694 Kehl / DE
Opponent's representative
Baumann, Rüdiger Walter, et al, et al
Pfister & Pfister
Patent- & Rechtsanwälte
Hallhof 6-7
87700 Memmingen / DE
22.07.2015Invitation to proprietor to file observations on the notice of opposition
01.02.2016Reply of patent proprietor to notice(s) of opposition
21.11.2016Legal effect of interlocutory decision in opposition
21.11.2016Date of oral proceedings
13.12.2016Despatch of interlocutory decision in opposition
13.12.2016Despatch of minutes of oral proceedings
05.04.2017Despatch of communication that the patent will be maintained as amended
17.07.2017Fee for printing new specification paid
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
12.07.2012Request for further processing filed
12.07.2012Full payment received (date of receipt of payment)
Request granted
25.07.2012Decision despatched
Fees paidRenewal fee
07.01.2008Renewal fee patent year 03
05.06.2009Renewal fee patent year 04
31.03.2010Renewal fee patent year 05
07.06.2011Renewal fee patent year 06
31.03.2012Renewal fee patent year 07
10.06.2013Renewal fee patent year 08
12.06.2014Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU07.06.2006
AT17.09.2014
BE17.09.2014
BG17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
MC17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SI17.09.2014
SK17.09.2014
TR17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
IE07.06.2015
LU07.06.2015
CH30.06.2015
LI30.06.2015
[2017/46]
Former [2017/39]HU07.06.2006
AT17.09.2014
BG17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
MC17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SI17.09.2014
SK17.09.2014
TR17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
IE07.06.2015
LU07.06.2015
CH30.06.2015
LI30.06.2015
Former [2016/22]AT17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
MC17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SI17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
IE07.06.2015
LU07.06.2015
CH30.06.2015
LI30.06.2015
Former [2016/20]AT17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
MC17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SI17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
IE07.06.2015
LU07.06.2015
Former [2016/11]AT17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
MC17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SI17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
LU07.06.2015
Former [2016/09]AT17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
MC17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SI17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
Former [2015/50]AT17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SI17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
Former [2015/34]AT17.09.2014
CY17.09.2014
CZ17.09.2014
DK17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
Former [2015/25]AT17.09.2014
CY17.09.2014
CZ17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
Former [2015/24]CY17.09.2014
CZ17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
NL17.09.2014
PL17.09.2014
RO17.09.2014
SE17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
Former [2015/23]CY17.09.2014
CZ17.09.2014
EE17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
NL17.09.2014
RO17.09.2014
SE17.09.2014
SK17.09.2014
GR18.12.2014
IS17.01.2015
PT19.01.2015
Former [2015/22]CY17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
NL17.09.2014
RO17.09.2014
SE17.09.2014
GR18.12.2014
PT19.01.2015
Former [2015/16]CY17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
NL17.09.2014
SE17.09.2014
GR18.12.2014
Former [2015/12]CY17.09.2014
FI17.09.2014
LT17.09.2014
LV17.09.2014
SE17.09.2014
GR18.12.2014
Former [2015/11]CY17.09.2014
FI17.09.2014
LT17.09.2014
SE17.09.2014
GR18.12.2014
Former [2015/09]FI17.09.2014
LT17.09.2014
SE17.09.2014
Former [2015/08]LT17.09.2014
Documents cited:Search[X]US2003053998  (DAEMEN MARC A R C [NL], et al) [X] 1-15 * claims 1,9,13 *;
 [X]  - DAEMEN MARC A R C ET AL, "Functional protection by acute phase proteins alpha1-acid glycoprotein and alpha1-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation", CIRCULATION, (20000919), vol. 102, no. 12, ISSN 0009-7322, pages 1420 - 1426, XP002544513 [X] 1-15 * abstract *
 [A]  - BREIT S N ET AL, "The role of alpha1-antitrypsin deficiency in the pathogenesis of immune disorders", CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, SAN DIEGO, CA, US, vol. 35, no. 3, ISSN 0090-1229, (19850601), pages 363 - 380, (19850601), XP026189357 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1016/0090-1229(85)90097-2
 [A]  - SONG S ET AL, "Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice", GENE THERAPY, MACMILLAN PRESS LTD., BASINGSTOKE, GB, (20040101), vol. 11, no. 2, ISSN 0969-7128, pages 181 - 186, XP002517682 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1038/SJ.GT.3302156
 [PX]  - LEWIS E C ET AL, "alpha1-Antitrypsin Monotherapy Prolongs Islet Allograft Survival in Mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, (20050823), vol. 102, no. 34, ISSN 0027-8424, pages 12153 - 12158, XP003011675 [PX] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1073/pnas.0505579102
International search[X]WO0051624  (TRUSTEES OF UNIVERSITY TECHNOL [US])
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.