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Extract from the Register of European Patents

EP About this file: EP1910302

EP1910302 - CARBONYL SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 RECEPTOR MODULATORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  28.06.2013
Database last updated on 15.06.2024
Most recent event   Tooltip28.06.2013Application deemed to be withdrawnpublished on 31.07.2013  [2013/31]
Applicant(s)For all designated states
Laboratorios del Dr. Esteve S.A.
Av. Mare de Déu de Montserrat, 221
08041 Barcelona / ES
[2008/16]
Inventor(s)01 / BUSCHMANN, Helmut, H.
Carrer dels Avellaners, 11
E-08960-Sant Just Desvern / ES
02 / TORRENS JOVER, Antonio
C/Racó, 8, 2 2a
E-08221 Terrasa / ES
03 / MAS PRIO, Jose
C/ Cal Princep, 39
08191 Rubi / ES
04 / QUINTANA RUIZ, Jordi Ramón
Carrer de les Aigues, 12
E-08391 Tiana / ES
05 / DORDAL ZUERAS, Alberto
C/Maladeta, 26 3 3a
E-08016 Barcelona / ES
 [2008/16]
Representative(s)Peters, Hajo, et al
ZACCO GmbH
Bayerstrasse 83
80335 München / DE
[N/P]
Former [2010/37]Peters, Hajo, et al
Albihns Zacco GmbH Bayerstrasse 83
80335 München / DE
Former [2009/29]Peters, Hajo, et al
Graf von Stosch Patentanwaltsgesellschaft mbH Prinzregentenstrasse 22
80538 München / DE
Former [2008/52]Peters, Hajo, et al
Graf von Stosch Patentanwaltsgesellschaft mbH Prinzregentenstrasse 22
80538 München / DE
Former [2008/40]Peters, Hajo, et al
Bosch Graf von Stosch Jehle Patentanwaltsgesellschaft mbH Prinzregentenstrasse 22
80538 München / DE
Former [2008/16]Peters, Hajo, et al
Bosch Graf von Stosch Jehle Patentanwaltsgesellschaft mbH Flüggenstrasse 13
80639 München / DE
Application number, filing date06776259.115.07.2006
[2008/16]
WO2006EP06961
Priority number, dateEP2005038401815.07.2005         Original published format: EP 05384018
EP2006000857926.04.2006         Original published format: EP 06008579
EP2006000858026.04.2006         Original published format: EP 06008580
EP2006000858126.04.2006         Original published format: EP 06008581
EP2006000861226.04.2006         Original published format: EP 06008612
US20050705433P05.08.2005         Original published format: US 705433 P
[2008/16]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007009687
Date:25.01.2007
Language:EN
[2007/04]
Type: A1 Application with search report 
No.:EP1910302
Date:16.04.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 25.01.2007 takes the place of the publication of the European patent application.
[2008/16]
Search report(s)International search report - published on:EP25.01.2007
ClassificationIPC:C07D231/06, C07D403/12, C07D401/06, C07D403/06, C07D495/04, A61K31/4155, A61P3/04
[2008/16]
CPC:
C07D231/06 (EP); A61P3/04 (EP); C07D401/06 (EP);
C07D403/06 (EP); C07D403/12 (EP); C07D495/04 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/16]
TitleGerman:CARBONYLSUBSTITUIERTE PYRAZOLINVERBINDUNGEN, IHRE HERSTELLUNG UND IHRE VERWENDUNG ALS MODULATOREN DES CB1-REZEPTORS[2008/16]
English:CARBONYL SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS CB1 RECEPTOR MODULATORS[2008/16]
French:COMPOSES DE PYRAZOLINE A SUBSTITUTION CARBONYLE, PREPARATION DE CEUX-CI ET UTILISATION DE CEUX-CI COMME MODULATEURS DES RECEPTEURS CB1[2008/16]
Entry into regional phase05.02.2008National basic fee paid 
05.02.2008Designation fee(s) paid 
05.02.2008Examination fee paid 
Examination procedure05.02.2008Examination requested  [2008/16]
14.08.2009Despatch of a communication from the examining division (Time limit: M06)
24.02.2010Reply to a communication from the examining division
08.09.2011Despatch of a communication from the examining division (Time limit: M06)
16.02.2012Reply to a communication from the examining division
01.02.2013Application deemed to be withdrawn, date of legal effect  [2013/31]
11.03.2013Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2013/31]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.08.2009
Fees paidRenewal fee
26.03.2008Renewal fee patent year 03
13.07.2009Renewal fee patent year 04
12.07.2010Renewal fee patent year 05
14.07.2011Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.07.201207   M06   Not yet paid
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Cited inInternational search[PX]WO2005077911  (ESTEVE LABOR DR [ES], et al) [PX] 1-14,16-30 * claims 1,9,23-34 *;
 [PX]WO2005074920  (SOLVAY PHARM BV [NL], et al) [PX] 1-14,16-30 * claims 1,8-12; compounds 1-4 *;
 [A]  - LANGE J H M ET AL, "SYNTHESIS, BIOLOGICAL PROPERTIES, AND MOLECULAR MODELING INVESTIGATIONS OF NOVEL 3,4-DIARYLPYRAZOLINES AS POTENT AND SELECTIVE CB1 CANNABINOID RECEPTOR ANTAGONISTS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (2004), vol. 47, no. 3, ISSN 0022-2623, pages 627 - 643, XP001188902 [A] 1-30 * compound 1 *

DOI:   http://dx.doi.org/10.1021/jm031019q
 [A]  - THOMAS ET AL, "Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)- 4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities", BIOORGANIC & MEDICINAL CHEMISTRY, ELSEVIER SCIENCE LTD, GB, (20050701), vol. 13, no. 18, ISSN 0968-0896, pages 5463 - 5474, XP005021048 [A] 1-30 * compounds 5-27 *

DOI:   http://dx.doi.org/10.1016/j.bmc.2005.06.005
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.