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Extract from the Register of European Patents

EP About this file: EP1904460

EP1904460 - MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.03.2013
Database last updated on 17.05.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
BRACCO IMAGING S.p.A.
Via E. Folli 50
20134 Milano / IT
[2008/14]
Inventor(s)01 / GIOVENZANA, Giovanni B., Bracco Imaging S.p.A.
Viaia E. Folli, 50
I-20134 Milano / IT
02 / PALMISANO, Giovanni, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
03 / SISTI, Massimo, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
04 / CAVALLOTTI, Camilla, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
05 / AIME, Silvio, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
06 / CALABI, Luisella, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
07 / SWENSON, Rolf, Bracco Research USA
305 College Road East
Princeton, NJ 08540 / US
08 / KONDAREDDIAR, Ramalingam, Bracco Research USA
305 College Road East
Princeton, NJ 08540 / US
09 / LATTUADA, Luciano, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
10 / MOROSINI, Pierfrancesco, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
 [2012/20]
Former [2008/14]01 / GIOVENZANA, Giovanni B., Bracco Imaging S.p.A.
Viaia E. Folli, 50
I-20134 Milano / IT
02 / PALMISANO, Giovanni, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
03 / SISTI, Massimo, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
04 / CAVALLOTTI, Camilla, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
05 / AIME, Silvio, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
06 / CALABI, Luisella, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
07 / SWENSON, Rolf, Bracco Research USA
305 College Road East
Princeton, NJ 08540 / US
08 / KONDAREDDIAR, Ramalingam, Bracco Research USA
305 College Road East
Princeton, NJ 08540 / US
09 / LATTUADA, Luciano, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
10 / MOROSINI, Pierfrancesco, Bracco Imaging S.p.A.
Via E. Folli, 50
I-20134 Milano / IT
Representative(s)Macchetta, Francesco, et al
Bracco Imaging SpA
IP Department
Via Caduti di Marcinelle 13
20134 Milano / IT
[N/P]
Former [2012/20]Macchetta, Francesco, et al
Bracco Imaging S.p.A.
IP Department
Via XXV Aprile, 4
20097 San Donato Milanese (MI) / IT
Former [2009/47]Macchetta, Francesco, et al
Bracco Imaging S.p.A. IP Department Via XXV Aprile, 4
20097 San Donato Milanese (MI) / IT
Former [2008/14]Poletti, Marco
Bracco Imaging S.p.A. IP Department Via XXV Aprile, 4
20097 San Donato Milanese (MI) / IT
Application number, filing date06777373.920.06.2006
[2008/14]
WO2006EP63368
Priority number, dateUS2005016579324.06.2005         Original published format: US 165793
[2008/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2006136564
Date:28.12.2006
Language:EN
[2006/52]
Type: A1 Application with search report 
No.:EP1904460
Date:02.04.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 28.12.2006 takes the place of the publication of the European patent application.
[2008/14]
Type: B1 Patent specification 
No.:EP1904460
Date:16.05.2012
Language:EN
[2012/20]
Search report(s)International search report - published on:EP28.12.2006
ClassificationIPC:C07D243/08, C07D243/14, C07C229/16, C07F9/38, A61K49/14
[2008/14]
CPC:
C07C209/62 (EP,US); A61K49/0002 (EP,US); A61K49/085 (EP,US);
A61K49/106 (EP,US); A61K49/122 (EP,US); A61K49/14 (EP,US);
A61K51/088 (EP,US); A61P35/00 (EP); A61P43/00 (EP);
A61P7/02 (EP); A61P9/10 (EP); C07D243/08 (EP,US);
C07D243/14 (EP,US); C07F9/301 (EP,US); C07F9/3808 (EP,US);
C07F9/4816 (EP,US); C07F9/645 (EP,US) (-)
C-Set:
C07C209/62, C07C211/50 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/14]
TitleGerman:MEHRZÄHNIGE, ZUR KOMPLEXIERUNG VON METALLIONEN GEEIGNETE AZA LIGANDEN UND DEREN VERWENDUNG IN DIAGNOSE UND THERAPIE[2008/14]
English:MULTIDENTATE AZA LIGANDS ABLE TO COMPLEX METAL IONS AND THE USE THEREOF IN DIAGNOSTICS AND THERAPY[2008/14]
French:LIGANDS AZA MULTIDENTES COMPLEXANTS D'IONS METALLIQUES ET UTILISATION DANS DES METHODES DIAGNOSTIQUES ET THERAPEUTIQUES[2008/14]
Entry into regional phase21.01.2008National basic fee paid 
21.01.2008Designation fee(s) paid 
21.01.2008Examination fee paid 
Examination procedure21.01.2008Examination requested  [2008/14]
30.09.2008Despatch of a communication from the examining division (Time limit: M08)
17.07.2009Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
28.07.2009Reply to a communication from the examining division
02.12.2009Despatch of a communication from the examining division (Time limit: M04)
30.03.2010Reply to a communication from the examining division
26.08.2010Despatch of a communication from the examining division (Time limit: M06)
02.03.2011Reply to a communication from the examining division
10.11.2011Communication of intention to grant the patent
10.02.2012Fee for grant paid
10.02.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  30.09.2008
Opposition(s)19.02.2013No opposition filed within time limit [2013/17]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
28.07.2009Request for further processing filed
28.07.2009Full payment received (date of receipt of payment)
Fees paidRenewal fee
25.06.2008Renewal fee patent year 03
26.06.2009Renewal fee patent year 04
25.06.2010Renewal fee patent year 05
27.06.2011Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU20.06.2006
AT16.05.2012
CY16.05.2012
CZ16.05.2012
EE16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
RO16.05.2012
SI16.05.2012
SK16.05.2012
TR16.05.2012
IE20.06.2012
LU20.06.2012
MC30.06.2012
BG16.08.2012
GR17.08.2012
IS16.09.2012
[2014/34]
Former [2014/27]AT16.05.2012
CY16.05.2012
CZ16.05.2012
EE16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
RO16.05.2012
SI16.05.2012
SK16.05.2012
TR16.05.2012
IE20.06.2012
LU20.06.2012
MC30.06.2012
BG16.08.2012
GR17.08.2012
IS16.09.2012
Former [2014/21]AT16.05.2012
CY16.05.2012
CZ16.05.2012
EE16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
RO16.05.2012
SI16.05.2012
SK16.05.2012
TR16.05.2012
IE20.06.2012
MC30.06.2012
BG16.08.2012
GR17.08.2012
IS16.09.2012
Former [2013/34]AT16.05.2012
CY16.05.2012
CZ16.05.2012
EE16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
RO16.05.2012
SI16.05.2012
SK16.05.2012
IE20.06.2012
MC30.06.2012
BG16.08.2012
GR17.08.2012
IS16.09.2012
Former [2013/20]AT16.05.2012
CY16.05.2012
CZ16.05.2012
EE16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
RO16.05.2012
SI16.05.2012
SK16.05.2012
IE20.06.2012
MC30.06.2012
GR17.08.2012
IS16.09.2012
Former [2013/10]AT16.05.2012
CY16.05.2012
CZ16.05.2012
EE16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
RO16.05.2012
SI16.05.2012
SK16.05.2012
MC30.06.2012
GR17.08.2012
IS16.09.2012
Former [2013/09]AT16.05.2012
CY16.05.2012
EE16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
SI16.05.2012
MC30.06.2012
GR17.08.2012
IS16.09.2012
Former [2013/08]AT16.05.2012
CY16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
SI16.05.2012
MC30.06.2012
GR17.08.2012
IS16.09.2012
Former [2013/07]AT16.05.2012
CY16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
SI16.05.2012
GR17.08.2012
IS16.09.2012
Former [2012/51]CY16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
SI16.05.2012
GR17.08.2012
IS16.09.2012
Former [2012/50]CY16.05.2012
FI16.05.2012
LT16.05.2012
LV16.05.2012
PL16.05.2012
GR17.08.2012
IS16.09.2012
Former [2012/49]CY16.05.2012
FI16.05.2012
LT16.05.2012
PL16.05.2012
IS16.09.2012
Former [2012/48]FI16.05.2012
LT16.05.2012
Former [2012/47]LT16.05.2012
Cited inInternational search[X]GB926351  (GEIGY AG J R) [X] 37 * example -; claim - *;
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 [DY]US2004136906  (CAPPELLETTI ENRICO [IT], et al) [DY] 1-43* figure -; example -; claim - *;
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 [X]  - S. AIME ET. AL., "[Gd-AAZTA]-. A New Structural Entry for an Improved Generation of MRI Contrast Agents. whole", INORGANIC CHEMISTRY, (2004), vol. 43, pages 7588 - 7590, XP002399530 [X] 37,38 * whole article *

DOI:   http://dx.doi.org/10.1021/ic0489692
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DOI:   http://dx.doi.org/10.1021/cr980440x
 [Y]  - K. TAKENOUCHI ET. AL., "Novel Bifunctional Macrocyclic Chelating agents Appended with a Pendant-Type Carboxymethylamino Ligand and Nitrobenzyl Group and Stability of the 88Y(III) Complexes.", JOURNAL OF ORGANIC CHEMISTRY, (1999), vol. 58, pages 1955 - 1958, XP002399531 [Y] 1-43 * page 1956, scheme 1, experimental section. *

DOI:   http://dx.doi.org/10.1021/jo00059a062
 [DY]  - D. BLOK ET. AL., "Peptide Radiopharmaceuticals in Nuclear Medicine", EUROPEAN JOURNAL OF NUCLEAR MEDICINE, (1999), vol. 26, pages 1511 - 1519, XP002399532 [DY] 1-43 * whole article *

DOI:   http://dx.doi.org/10.1007/s002590050488
by applicantUS4885363
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