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Extract from the Register of European Patents

EP About this file: EP2029138

EP2029138 - AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  17.04.2015
Database last updated on 15.06.2024
Most recent event   Tooltip17.04.2015Application deemed to be withdrawnpublished on 20.05.2015  [2015/21]
Applicant(s)For all designated states
Xenon Pharmaceuticals Inc.
3650 Gilmore Way
Burnaby, BC V5G 4W8 / CA
[N/P]
Former [2009/10]For all designated states
Xenon Pharmaceuticals Inc.
3650 Gilmore Way
Burnaby, British Columbia V5G 4W8 / CA
Inventor(s)01 / FU, Jianmin
3170 Quintette Crescent
Coquitlam, British Columbia V3E 3B6 / CA
02 / HOU, Duanjie
46-7088 17th Avenue
Burnaby, BC V3N 1K5 / CA
03 / KAMBOJ, Rajender
5809 Sperling Avenue
Burnaby, British Columbia V5E 2T6 / CA
04 / KODUMURU, Vishnumurthy
7480 Vista Cres.
Burnaby, British Columbia V5E 2E1 / CA
05 / POKROVSKAIA, Natalia
100-845 Mcbride Blvd
New Westminster, BC V3L 2C2 / CA
06 / RAINA, Vandna
6654 Linden Avenue
Burnaby, British Columbia V5E 3G4 / CA
07 / SUN, Shaoyi
5-1200 Brunette Avenue
Coquitlam, British Columbia V3K 1G3 / CA
08 / SVIRIDOV, Serguei
1904-5885 Olive Avenue
Burnaby, British Columbia V5H 4N8 / CA
09 / ZHANG, Zaihui
4038 MacDonald Street
Vancouver, British Columbia V6L 2N9 / CA
 [2009/10]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[N/P]
Former [2009/10]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Leopoldstrasse 4
80802 München / DE
Application number, filing date06784578.405.06.2006
[2009/10]
WO2006US21660
Priority number, dateUS20050687133P03.06.2005         Original published format: US 687133 P
[2012/42]
Former [2009/10]US20060687133P03.06.2006
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007130075
Date:15.11.2007
Language:EN
[2007/46]
Type: A1 Application with search report 
No.:EP2029138
Date:04.03.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 15.11.2007 takes the place of the publication of the European patent application.
[2009/10]
Search report(s)International search report - published on:EP15.11.2007
ClassificationIPC:A61K31/426, A61K31/427, A61K31/4439, A61P3/00, A61P9/12, A61P17/06, A61P17/10, A61P19/06, C07D277/82, C07D417/12
[2009/10]
CPC:
A61K31/426 (EP,US); C07D277/587 (US); A61K31/427 (EP,US);
A61K31/4439 (EP,US); A61K31/5377 (US); A61K31/616 (US);
A61K38/26 (US); A61K38/28 (US); A61K45/06 (US);
A61P1/16 (EP); A61P17/00 (EP); A61P17/02 (EP);
A61P17/06 (EP); A61P17/08 (EP); A61P17/10 (EP);
A61P19/06 (EP); A61P3/00 (EP); A61P3/04 (EP);
A61P3/06 (EP); A61P3/10 (EP); A61P35/00 (EP);
A61P43/00 (EP); A61P7/02 (EP); A61P9/10 (EP);
A61P9/12 (EP); C07D277/56 (EP,US); C07D417/06 (US);
C07D417/12 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/10]
TitleGerman:AMINOTHIAZOLDERIVATE ALS HUMANE STEAROYL-COA DESATURASEHEMMER[2009/10]
English:AMINOTHIAZOLE DERIVATIVES AS HUMAN STEAROYL-COA DESATURASE INHIBITORS[2009/10]
French:DERIVES AMINOTHIAZOLE UTILISES EN TANT QU'INHIBITEURS DE LA STEAROYLE-COA DESATURASE HUMAINE[2009/10]
Entry into regional phase28.12.2007National basic fee paid 
28.12.2007Designation fee(s) paid 
28.12.2007Examination fee paid 
Examination procedure28.12.2007Examination requested  [2009/10]
13.08.2010Despatch of a communication from the examining division (Time limit: M06)
31.01.2011Reply to a communication from the examining division
21.07.2014Despatch of a communication from the examining division (Time limit: M04)
02.12.2014Application deemed to be withdrawn, date of legal effect  [2015/21]
14.01.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/21]
Divisional application(s)EP12005821.9  / EP2540296
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  13.08.2010
Fees paidRenewal fee
25.06.2008Renewal fee patent year 03
26.06.2009Renewal fee patent year 04
25.06.2010Renewal fee patent year 05
27.06.2011Renewal fee patent year 06
26.06.2012Renewal fee patent year 07
27.06.2013Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
30.06.201409   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[DA]WO2005011655  (XENON PHARMACEUTICALS INC [CA], et al) [DA] 1-24* Page 144, lines 16-17,; page 1, line 3 - line 8 *;
 [X]  - WITYAK, JOHN ET AL, "Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 13(22), 4007-4010 CODEN: BMCLE8; ISSN: 0960-894X, (2003), XP002402709 [X] 11,21,23 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2003.08.054
 [X]  - OHKUBO, MITSURU ET AL, "Studies on cerebral protective agents. VIII. Synthesis of 2-aminothiazoles and 2-thiazolecarboxamides with anti-anoxic activity", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1995:902192, URL: STN, XP002402712 [X] 11,21,23 * the whole document *
 [X]  - SINGH, S. N. ET AL, "New local anesthetics", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1972:564589, URL: STN, XP002402713 [X] 11,21,23 * the whole document *
ExaminationEP0518731
 US6114365
 WO0250071
 WO2004112782
 EP1244641
    - HELAL C J ET AL, "Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, (20041115), vol. 14, no. 22, doi:10.1016/J.BMCL.2004.09.006, ISSN 0960-894X, pages 5521 - 5525, XP004598586

DOI:   http://dx.doi.org/10.1016/j.bmcl.2004.09.006
    - MISRA RAJ N ET AL, "N-(cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase 2. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thi azolyl]-4- piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agent", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20040325), vol. 47, no. 7, doi:10.1021/JM0305568, ISSN 0022-2623, pages 1719 - 1728, XP002302339

DOI:   http://dx.doi.org/10.1021/jm0305568
    - KIM KYOUNG SOON ET AL, "DISCOVERY OF AMINOTHIAZOLE INHIBITORS OF CYCLIN-DEPENDENT KINASE 2: SYNTHESIS, X-RAY CRYSTALLOGRAPHIC ANALYSIS, AND BIOLOGICAL ACTIVITIES", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20020101), vol. 45, no. 18, doi:10.1021/JM0201520, ISSN 0022-2623, pages 3905 - 3927, XP009073889

DOI:   http://dx.doi.org/10.1021/jm0201520
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.