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Extract from the Register of European Patents

EP About this file: EP1910417

EP1910417 - Inhibitors of disintegrin-metalloproteinases [Right-click to bookmark this link]
Former [2008/16]COMPOUNDS
[2010/10]
StatusThe application is deemed to be withdrawn
Status updated on  03.12.2010
Database last updated on 03.06.2024
Most recent event   Tooltip03.12.2010Application deemed to be withdrawnpublished on 05.01.2011  [2011/01]
Applicant(s)For all designated states
Imperial Innovations Limited
Electrical and Electronic Engineering Building, Level 12, Imperial College Exhibition Road
London SW7 2AZ / GB
[2008/16]
Inventor(s)01 / NAGASE, Hideaki
Imperial College Londong, 1 Aspenlea Road
Hammersmith, London W6 8LH / GB
02 / BREW, Keith, Florida Atlantic University
Department of Biomedical Science
Boca Raton, FL 33431 / US
 [2008/16]
Representative(s)Pilkington, Stephanie Joan
Potter Clarkson LLP The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
[N/P]
Former [2008/16]Pilkington, Stephanie Joan
Potter Clarkson LLP Park View House 58 The Ropewalk
Nottingham NG1 5DD / GB
Application number, filing date06788978.228.07.2006
[2008/16]
WO2006US29726
Priority number, dateUS20050704015P29.07.2005         Original published format: US 704015 P
[2008/16]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007016482
Date:08.02.2007
Language:EN
[2007/06]
Type: A2 Application without search report 
No.:EP1910417
Date:16.04.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 08.02.2007 takes the place of the publication of the European patent application.
[2008/16]
Search report(s)International search report - published on:EP19.04.2007
ClassificationIPC:C07K14/81
[2008/16]
CPC:
C07K14/8146 (EP,US); A61P1/02 (EP); A61P1/04 (EP);
A61P1/14 (EP); A61P11/00 (EP); A61P17/06 (EP);
A61P19/02 (EP); A61P19/04 (EP); A61P27/02 (EP);
A61P27/06 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P31/00 (EP); A61P31/04 (EP); A61P33/06 (EP);
A61P35/00 (EP); A61P37/00 (EP); A61P37/06 (EP);
A61P7/00 (EP); A61P9/00 (EP); A61P9/10 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/16]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:Inhibitoren Disintegrin-Metalloproteinasen[2010/10]
English:Inhibitors of disintegrin-metalloproteinases[2010/10]
French:Inhibiteurs de disintégrine-métalloprotéinases[2010/10]
Former [2008/16]VERBINDUNGEN
Former [2008/16]COMPOUNDS
Former [2008/16]COMPOSES
Entry into regional phase09.02.2008National basic fee paid 
09.02.2008Designation fee(s) paid 
09.02.2008Examination fee paid 
Examination procedure09.02.2008Examination requested  [2008/16]
21.05.2008Despatch of a communication from the examining division (Time limit: M04)
28.08.2008Reply to a communication from the examining division
19.01.2009Despatch of a communication from the examining division (Time limit: M06)
14.07.2009Reply to a communication from the examining division
22.02.2010Communication of intention to grant the patent
06.07.2010Application deemed to be withdrawn, date of legal effect  [2011/01]
06.08.2010Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2011/01]
Fees paidRenewal fee
31.03.2008Renewal fee patent year 03
27.07.2009Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.07.201005   M06   Not yet paid
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Cited inInternational search[X]WO9509918  (AMGEN INC [US]) [X] 1-5 * sequence 15 *;
 JPH09235300  [ ] (FUJI YAKUHIN KOGYO KK) [ ] * abstract *;
 [X]  - "Human TIMP-1/TIMP-3 fusion protein.", Geneseq, (19980129), Database accession no. AAW30310, URL: EBI, XP002417757 [X] 1-5 * the whole document *
 [A]  - LANGTON KEVIN P ET AL, "Localization of the functional domains of human tissue inhibitor of metalloproteinases-3 and the effects of a Sorsby's fundus dystrophy mutation", JOURNAL OF BIOLOGICAL CHEMISTRY, (19980703), vol. 273, no. 27, ISSN 0021-9258, pages 16778 - 16781, XP002417706 [A] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.273.27.16778
 [DA]  - WINGFIELD PAUL T ET AL, "Biophysical and functional characterization of full-length, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli. Comparison of wild type and amino-terminal alanine appended variant with implications for the mechanism of TIMP functions", JOURNAL OF BIOLOGICAL CHEMISTRY, (19990723), vol. 274, no. 30, ISSN 0021-9258, pages 21362 - 21368, XP002417707 [DA] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.274.30.21362
 [A]  - WEI SHUO ET AL, "Protein engineering of the tissue inhibitor of metalloproteinase 1 (TIMP-1) inhibitory domain. In search of selective matrix metalloproteinase inhibitors.", JOURNAL OF BIOLOGICAL CHEMISTRY, (20030314), vol. 278, no. 11, ISSN 0021-9258, pages 9831 - 9834, XP002417708 [A] 1-14 * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.M211793200
 [PX]  - WEI S ET AL, "Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-[alpha]-converting enzyme", JOURNAL OF BIOLOGICAL CHEMISTRY 23 SEP 2005 UNITED STATES, (20050923), vol. 280, no. 38, ISSN 0021-9258, pages 32877 - 32882, XP002417709 [PX] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.C500220200
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