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Extract from the Register of European Patents

EP About this file: EP1909812

EP1909812 - SMALL COMPOUNDS THAT CORRECT PROTEIN MISFOLDING AND USES THEREOF [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.11.2013
Database last updated on 11.09.2024
Most recent event   Tooltip15.11.2013Application deemed to be withdrawnpublished on 18.12.2013  [2013/51]
Applicant(s)For all designated states
University of Florida Research Foundation, Inc.
223 Grinter Hall University of Florida PO Box 115500
Gainesville, FL 32611-5500 / US
[2008/16]
Inventor(s)01 / KAUSHAL, Shalesh
6205 NW 81st Drive
Gainesville, FL 32653 / US
02 / NOORWEZ, Syed, Mohammed
3461 S.W. 2nd Ave. No. 252
Gainesville, FL 32607 / US
 [2008/16]
Representative(s)Grund, Martin, et al
Grund Intellectual Property Group
Patentanwälte und Solicitor PartG mbB
Steinsdorfstraße 2
80538 München / DE
[N/P]
Former [2008/16]Grund, Martin, et al
GRUND Intellectual Property Group Postfach 44 05 16
80754 München / DE
Application number, filing date06800453.027.07.2006
[2008/16]
WO2006US29402
Priority number, dateUS20050703068P27.07.2005         Original published format: US 703068 P
[2008/16]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007014327
Date:01.02.2007
Language:EN
[2007/05]
Type: A2 Application without search report 
No.:EP1909812
Date:16.04.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 01.02.2007 takes the place of the publication of the European patent application.
[2008/16]
Search report(s)International search report - published on:US30.04.2009
(Supplementary) European search report - dispatched on:EP27.10.2009
ClassificationIPC:A61P27/06, A61P25/02, A61P27/02, A61K33/02, A61K31/395, A61K31/445, A61P11/00, A61P13/02, A61P25/16, A61P25/28, A61P35/00
[2009/26]
CPC:
A61K31/11 (EP,US); A61K31/21 (KR); A61K31/047 (EP,US);
A61K31/16 (EP,US); A61K31/19 (EP,US); A61K31/223 (EP,US);
A61K31/225 (KR); A61K31/365 (EP,US); A61K31/395 (EP,US);
A61K31/4015 (EP,US); A61K31/473 (EP,US); A61K31/52 (EP,US);
A61K33/02 (EP,US); A61K38/04 (KR); A61K45/06 (EP,US);
A61P11/00 (EP); A61P13/02 (EP); A61P25/02 (EP);
A61P25/16 (EP); A61P25/28 (EP); A61P27/02 (EP);
A61P27/06 (EP); A61P35/00 (EP); A61P43/00 (EP);
A61P9/10 (EP) (-)
C-Set:
A61K31/047, A61K2300/00 (US,EP);
A61K31/11, A61K2300/00 (US,EP);
A61K31/16, A61K2300/00 (US,EP);
A61K31/19, A61K2300/00 (US,EP);
A61K31/223, A61K2300/00 (EP,US);
A61K31/365, A61K2300/00 (EP,US);
A61K31/395, A61K2300/00 (EP,US);
A61K31/4015, A61K2300/00 (EP,US);
A61K31/473, A61K2300/00 (EP,US);
A61K31/52, A61K2300/00 (US,EP);
A61K33/02, A61K2300/00 (US,EP)
(-)
Former IPC [2008/16]A61K38/04
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/16]
TitleGerman:KLEINE VERBINDUNGEN ZUR KORREKTUR VON PROTEIN-MISSFALTUNGEN UND VERWENDUNGEN DAVON[2008/16]
English:SMALL COMPOUNDS THAT CORRECT PROTEIN MISFOLDING AND USES THEREOF[2008/16]
French:PETITS COMPOSES CORRIGEANT UN MAUVAIS REPLIEMENT DES PROTEINES ET UTILISATIONS DE CEUX-CI[2008/16]
Entry into regional phase23.01.2008National basic fee paid 
23.01.2008Search fee paid 
23.01.2008Designation fee(s) paid 
23.01.2008Examination fee paid 
Examination procedure23.01.2008Examination requested  [2008/16]
02.04.2008Amendment by applicant (claims and/or description)
02.03.2010Despatch of a communication from the examining division (Time limit: M06)
06.07.2010Reply to a communication from the examining division
20.09.2011Despatch of a communication from the examining division (Time limit: M04)
17.01.2012Reply to a communication from the examining division
04.02.2013Despatch of a communication from the examining division (Time limit: M04)
15.06.2013Application deemed to be withdrawn, date of legal effect  [2013/51]
25.07.2013Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2013/51]
Divisional application(s)EP11169183.8  / EP2374451
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  02.03.2010
Fees paidRenewal fee
25.07.2008Renewal fee patent year 03
28.07.2009Renewal fee patent year 04
26.07.2010Renewal fee patent year 05
25.07.2011Renewal fee patent year 06
25.07.2012Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
31.07.201308   M06   Not yet paid
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Documents cited:Search[A]US2004092431  (HELLBERG PEGGY E [US]) [A] * page 2, paragraph 9 * * page 3; claim 1 ** page 4; claim 4 *;
 [XY]  - INDEN M ET AL, "Proteasome inhibitors protect against degeneration of nigral dopaminergic neurons in hemiparkinsonian rats", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, (20050101), vol. 97, ISSN 0022-3549, pages 203 - 211, XP003016157 [X] 1,5,11,12 * abstract * * page 205, column LEFT * * page 210, column RIGHT * [Y] 6

DOI:   http://dx.doi.org/10.1254/jphs.FP0040525
 [Y]  - NOORWEZ ET AL, "Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa", JBC PAPERS IN PRESS, XX, XX, (20030101), vol. 278, no. 16, pages 14442 - 14450, XP008103178 [Y] 6 * abstract * * page 14442 * * page 14450 *
 [Y]  - NOORWEZ ET AL, "Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H", JBC PAPERS IN PRESS, XX, XX, (20040401), vol. 279, no. 16, pages 16278 - 16284, XP008103188 [Y] 6 * page 16278 * * page 16282, column LEFT * * page 16283, column RIGHT *
 [A]  - ILLING MICHELLE E ET AL, "A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 13 SEP 2002, (20020913), vol. 277, no. 37, ISSN 0021-9258, pages 34150 - 34160, XP002549069 [A] * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.M204955200
International search[Y]GB890638  (ALBERT B CHATZINOFF, et al);
 [Y]US3196078  (CHATZINOFF ALBERT B, et al);
 [X]US5112607  (HUDSON THOMAS H [US], et al);
 [X]CA1321356  (MERRELL DOW PHARMA [CA]);
 [X]WO9825573  (NEUROCAL INTERNATIONAL [US]);
 [X]WO0149290  (UNIV JOHNS HOPKINS [US], et al);
 [X]US2002086015  (GOLD BRUCE G [US]);
 [X]US2004220267  (DEVLIN J P [US]);
 [XP]US2006121039  (SHARIF NAJAM A [US]);
 [XP]WO2006078774  (UNIV PENNSYLVANIA [US], et al);
 [Y]  - SALIBA ET AL., "The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation", JOURNAL OF CELL SCIENCE, (2002), vol. 115, pages 2907 - 2918, XP008125346
 [X]  - BERGMANN ET AL., "Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration", THE FASEB JOURNAL, (2004), vol. 18, no. 3, pages 562 - 564, XP008130763

DOI:   http://dx.doi.org/10.1096/fj.03-0289fje
ExaminationJPH1036289
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.