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Extract from the Register of European Patents

EP About this file: EP1964918

EP1964918 - Protein which can serve as nucleus for polymerization of protein polymer and process for production of cells comprising said nucleus [Right-click to bookmark this link]
Former [2008/36]PROTEIN WHICH CAN SERVE AS NUCLEUS FOR POLYMERIZATION OF PROTEIN POLYMER, CELL HAVING THE POLYMER INTRODUCED THEREIN, AND PROCESS FOR PRODUCTION OF THE CELL
[2011/13]
StatusNo opposition filed within time limit
Status updated on  10.08.2012
Database last updated on 11.09.2024
Most recent event   Tooltip04.10.2013Lapse of the patent in a contracting state
New state(s): HU
published on 06.11.2013  [2013/45]
Applicant(s)For all designated states
Tokyo Metropolitan Institute of Medical Science
1-6, Kamikitazawa 2-chome Setagaya-ku
Tokyo 156-0057 / JP
[2011/44]
Former [2011/39]For all designated states
Tokyo Metropolitan Institute of Medical Science (Incorporated Foundation)
1-6, Kamikitazawa 2-chome
Setagaya-ku
Tokyo 156-0057 / JP
Former [2011/37]For all designated states
Tokyo Metropolitan Institute of Medical Science
1-6, Kamikitazawa 2-chome Setagaya-ku
Tokyo 156-0057 / JP
Former [2010/01]For all designated states
Tokyo Metropolitan Organization for Medical Research
1-6, Kamikitazawa 2-chome Setagaya-ku
Tokyo 156-0057 / JP
Former [2008/36]For all designated states
Tokyo Metropolitan Organization for Medical Research
2-8-1, Nishi-shinjuku-ku
Tokyo, 163-8001 / JP
Inventor(s)01 / NONAKA, Takashi
8-27-18-504 Toshima
Kita-ku
Tokyo 114-0003 / JP
02 / WATANABE, Sayuri
1-2-35-603 Tsukaguchihonmachi
Amagasaki-shi, Hyogo 661-0001 / JP
03 / MASUDA, Masami
1525-1, Mizuko
Fujimi-shi, Saitama 354-0011 / JP
04 / HASEGAWA, Masato
3-46-36, Tamagawa
Chofu-shi, Tokyo 182-0025 / JP
 [2011/40]
Former [2008/36]01 / NONAKA, Takashi
8-27-18-504 Toshima, Kita-ku
Tokyo 114-0003 / JP
02 / WATANABE, Sayuri
1-2-35-603 Tsukaguchihonmachi
Amagasaki-shi, Hyogo 661-0001 / JP
03 / MASUDA, Masami
1525-1, Mizuko
Fujimi-shi, Saitama 354-0011 / JP
04 / HASEGAWA, Masato
3-46-36, Tamagawa
Chofu-shi, Tokyo 182-0025 / JP
Representative(s)Woods, Geoffrey Corlett
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[N/P]
Former [2011/40]Woods, Geoffrey Corlett
J.A. Kemp & Co. 14 South Square Gray's Inn London
WC1R 5JJ / GB
Former [2008/36]Woods, Geoffrey Corlett
J.A. KEMP & CO. 14 South Square Gray's Inn London
WC1R 5JJ / GB
Application number, filing date06834541.206.12.2006
[2008/36]
WO2006JP324786
Priority number, dateJP2005035248606.12.2005         Original published format: JP 2005352486
[2008/36]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007066809
Date:14.06.2007
Language:JA
[2007/24]
Type: A1 Application with search report 
No.:EP1964918
Date:03.09.2008
Language:EN
[2008/36]
Type: B1 Patent specification 
No.:EP1964918
Date:05.10.2011
Language:EN
[2011/40]
Type: B8 Corrected title page of specification 
No.:EP1964918
Date:28.03.2012
[2012/13]
Search report(s)International search report - published on:JP14.06.2007
(Supplementary) European search report - dispatched on:EP03.06.2009
ClassificationIPC:C07K14/47, C12Q1/02
[2011/40]
CPC:
C07K14/47 (EP,US); C12N5/0619 (EP,US); C12N5/0622 (EP,US);
G01N33/5058 (EP,US); G01N33/6896 (EP,US); C12N2503/02 (EP,US);
C12N2510/00 (EP,US); G01N2500/10 (EP,US) (-)
Former IPC [2008/36]C12N15/00, C12N5/10, C12N15/09, C12Q1/02
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/36]
Extension statesAL07.07.2008
BA07.07.2008
HR07.07.2008
MK07.07.2008
RS07.07.2008
TitleGerman:Protein mit möglicher eignung als Nukleus für die Polymerisierung eines Proteinpolymers, und Verfahren zur Herstellung von Zelle mit solchem Nukleus[2011/13]
English:Protein which can serve as nucleus for polymerization of protein polymer and process for production of cells comprising said nucleus[2011/13]
French:Protéine qui peut servir de noyau pour la polymérisation de polymère de protéine, et procédé pour la production des cellules contenant ce noyau[2011/13]
Former [2008/36]PROTEIN MIT MÖGLICHER EIGNUNG ALS NUKLEUS FÜR DIE POLYMERISIERUNG EINES PROTEINPOLYMERS, ZELLE MIT DEM DARIN EINGEFÜHRTEN POLYMER UND VERFAHREN ZUR HERSTELLUNG DER ZELLE
Former [2008/36]PROTEIN WHICH CAN SERVE AS NUCLEUS FOR POLYMERIZATION OF PROTEIN POLYMER, CELL HAVING THE POLYMER INTRODUCED THEREIN, AND PROCESS FOR PRODUCTION OF THE CELL
Former [2008/36]PROTEINE QUI PEUT SERVIR DE NOYAU POUR LA POLYMERISATION DE POLYMERE DE PROTEINE, CELLULE DANS LAQUELLE LE POLYMERE EST INTRODUIT, ET PROCEDE POUR LA PRODUCTION DE LA CELLULE
Entry into regional phase07.07.2008Translation filed 
07.07.2008National basic fee paid 
07.07.2008Search fee paid 
07.07.2008Designation fee(s) paid 
07.07.2008Examination fee paid 
Examination procedure07.07.2008Examination requested  [2008/36]
01.09.2008Amendment by applicant (claims and/or description)
22.09.2009Despatch of a communication from the examining division (Time limit: M06)
06.04.2010Reply to a communication from the examining division
17.09.2010Despatch of a communication from the examining division (Time limit: M02)
22.09.2010Reply to a communication from the examining division
18.04.2011Communication of intention to grant the patent
17.08.2011Fee for grant paid
17.08.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.09.2009
Opposition(s)06.07.2012No opposition filed within time limit [2012/37]
Fees paidRenewal fee
15.12.2008Renewal fee patent year 03
11.12.2009Renewal fee patent year 04
15.12.2010Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT05.10.2011
BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
HU05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
TR05.10.2011
IE06.12.2011
LU06.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
[2013/45]
Former [2013/44]AT05.10.2011
BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
TR05.10.2011
IE06.12.2011
LU06.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
Former [2013/29]AT05.10.2011
BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
IE06.12.2011
LU06.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
Former [2013/25]AT05.10.2011
BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
IE06.12.2011
LU06.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
Former [2013/22]AT05.10.2011
BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
IE06.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
Former [2013/07]AT05.10.2011
BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
IE06.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/49]BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
IE06.12.2011
CH31.12.2011
LI31.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/47]BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
IE06.12.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/37]BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/36]BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/35]BE05.10.2011
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
MC31.12.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/34]BE05.10.2011
CY05.10.2011
CZ05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
MC31.12.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/33]BE05.10.2011
CY05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
MC31.12.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/28]BE05.10.2011
CY05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/24]BE05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/23]BE05.10.2011
LT05.10.2011
NL05.10.2011
SI05.10.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/21]BE05.10.2011
LT05.10.2011
SI05.10.2011
IS05.02.2012
Former [2012/20]LT05.10.2011
SI05.10.2011
Former [2012/11]SI05.10.2011
Documents cited:Search[X]WO0213837  (LAYTON BIOSCIENCE INC [US], et al) [X] 1-6,10-12 * abstract *;
 [A]WO0210201  (ACTIVE MOTIF [US], et al) [A] 1-12 * the whole document *
 [X]  - KIRBY JANINE ET AL, "Differential gene expression in a cell culture model of SOD1-related familial motor neuron disease.", HUMAN MOLECULAR GENETICS 15 AUG 2002, (20020815), vol. 11, no. 17, ISSN 0964-6906, pages 2061 - 2075, XP002528432 [X] 1-6,10-12 * abstract *

DOI:   http://dx.doi.org/10.1093/hmg/11.17.2061
 [X]  - SHIMURA HIDEKI ET AL, "CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 6 FEB 2004, (20040206), vol. 279, no. 6, ISSN 0021-9258, pages 4869 - 4876, XP002528433 [X] 1-6,10-12 * abstract *

DOI:   http://dx.doi.org/10.1074/JBC.M305838200
 [X]  - PANDEY N ET AL, "The alpha-synuclein mutation E46K promotes aggregation in cultured cells", EXPERIMENTAL NEUROLOGY, ACADEMIC PRESS, NEW YORK, NY, US, online, vol. 197, no. 2, ISSN 0014-4886, (20051201), pages 515 - 520, (20060201), XP024945717 [X] 1-6,10-12 * abstract *

DOI:   http://dx.doi.org/10.1016/j.expneurol.2005.10.019
 [DA]  - JARRETT J T ET AL, "Seeding ''one-dimensional crystallization'' of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 73, no. 6, ISSN 0092-8674, (19930618), pages 1055 - 1058, (19930618), XP023873330 [DA] 1-12 * abstract *

DOI:   http://dx.doi.org/10.1016/0092-8674(93)90635-4
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