EP1897939 - Microorganism strain for producing recombinant proteins [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 09.09.2011 Database last updated on 15.06.2024 | Most recent event Tooltip | 04.10.2013 | Lapse of the patent in a contracting state New state(s): HU | published on 06.11.2013 [2013/45] | Applicant(s) | For all designated states Wacker Chemie AG Hanns-Seidel-Platz 4 81737 München / DE | [2008/11] | Inventor(s) | 01 /
Leonhartsberger, Susanne Sophienstraße 1 07743, Jena / DE | 02 /
Wich, Günter Haseneystraße 17 81377, München / DE | [2008/11] | Representative(s) | Potten, Holger, et al Wacker Chemie AG Zentralbereich Patente, Marken und Lizenzen Hanns-Seidel-Platz 4 81737 München / DE | [N/P] |
Former [2008/11] | Potten, Holger, et al Wacker Chemie AG Zentralbereich Patente, Marken und Lizenzen Hanns-Seidel-Platz 4 81737 München / DE | Application number, filing date | 07101292.6 | 29.01.2007 | [2008/11] | Priority number, date | DE20061004871 | 02.02.2006 Original published format: DE102006004871 | [2008/11] | Filing language | DE | Procedural language | DE | Publication | Type: | A2 Application without search report | No.: | EP1897939 | Date: | 12.03.2008 | Language: | DE | [2008/11] | Type: | A3 Search report | No.: | EP1897939 | Date: | 19.03.2008 | [2008/12] | Type: | B1 Patent specification | No.: | EP1897939 | Date: | 03.11.2010 | Language: | DE | [2010/44] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 14.02.2008 | Classification | IPC: | C12N15/00, C12N15/67, C12N1/00, C12N1/20 | [2008/11] | CPC: |
C12N15/70 (EP,US);
C12P21/02 (EP,US)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2008/11] | Title | German: | Mikroorganismenstamm zur Produktion von rekombinanten Proteinen | [2008/11] | English: | Microorganism strain for producing recombinant proteins | [2008/11] | French: | Procédé destiné à la fabrication d'une broche | [2008/11] | Biological material | This application mentions deposited biological material, check the file for details | Examination procedure | 29.01.2007 | Examination requested [2008/11] | 13.04.2007 | Loss of particular rights, legal effect: Drawings | 25.10.2007 | Despatch of communication of loss of particular rights: Drawings {1} | 01.04.2008 | Despatch of a communication from the examining division (Time limit: M04) | 23.07.2008 | Reply to a communication from the examining division | 29.08.2008 | Despatch of a communication from the examining division (Time limit: M04) | 17.12.2008 | Reply to a communication from the examining division | 16.01.2009 | Despatch of a communication from the examining division (Time limit: M06) | 01.07.2009 | Reply to a communication from the examining division | 17.07.2009 | Despatch of a communication from the examining division (Time limit: M04) | 16.11.2009 | Reply to a communication from the examining division | 26.11.2009 | Despatch of a communication from the examining division (Time limit: M04) | 31.03.2010 | Reply to a communication from the examining division | 16.06.2010 | Communication of intention to grant the patent | 16.09.2010 | Fee for grant paid | 16.09.2010 | Fee for publishing/printing paid | Divisional application(s) | EP10175511.4 / EP2298912 | EP10175512.2 / EP2418276 | Opposition(s) | 04.08.2011 | No opposition filed within time limit [2011/41] | Fees paid | Renewal fee | 14.01.2009 | Renewal fee patent year 03 | 22.01.2010 | Renewal fee patent year 04 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CY | 03.11.2010 | CZ | 03.11.2010 | EE | 03.11.2010 | FI | 03.11.2010 | HU | 03.11.2010 | IE | 03.11.2010 | LT | 03.11.2010 | LV | 03.11.2010 | PL | 03.11.2010 | RO | 03.11.2010 | SI | 03.11.2010 | SK | 03.11.2010 | TR | 03.11.2010 | LU | 29.01.2011 | MC | 31.01.2011 | BG | 03.02.2011 | GR | 04.02.2011 | ES | 14.02.2011 | IS | 03.03.2011 | PT | 03.03.2011 | [2013/45] |
Former [2013/44] | CY | 03.11.2010 | |
CZ | 03.11.2010 | ||
EE | 03.11.2010 | ||
FI | 03.11.2010 | ||
IE | 03.11.2010 | ||
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
PL | 03.11.2010 | ||
RO | 03.11.2010 | ||
SI | 03.11.2010 | ||
SK | 03.11.2010 | ||
TR | 03.11.2010 | ||
LU | 29.01.2011 | ||
MC | 31.01.2011 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
ES | 14.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2013/26] | CY | 03.11.2010 | |
CZ | 03.11.2010 | ||
EE | 03.11.2010 | ||
FI | 03.11.2010 | ||
IE | 03.11.2010 | ||
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
PL | 03.11.2010 | ||
RO | 03.11.2010 | ||
SI | 03.11.2010 | ||
SK | 03.11.2010 | ||
LU | 29.01.2011 | ||
MC | 31.01.2011 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
ES | 14.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2013/25] | CZ | 03.11.2010 | |
EE | 03.11.2010 | ||
FI | 03.11.2010 | ||
IE | 03.11.2010 | ||
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
PL | 03.11.2010 | ||
RO | 03.11.2010 | ||
SI | 03.11.2010 | ||
SK | 03.11.2010 | ||
LU | 29.01.2011 | ||
MC | 31.01.2011 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
ES | 14.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2011/38] | CZ | 03.11.2010 | |
EE | 03.11.2010 | ||
FI | 03.11.2010 | ||
IE | 03.11.2010 | ||
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
PL | 03.11.2010 | ||
RO | 03.11.2010 | ||
SI | 03.11.2010 | ||
SK | 03.11.2010 | ||
MC | 31.01.2011 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
ES | 14.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2011/36] | CZ | 03.11.2010 | |
EE | 03.11.2010 | ||
FI | 03.11.2010 | ||
IE | 03.11.2010 | ||
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
PL | 03.11.2010 | ||
SI | 03.11.2010 | ||
SK | 03.11.2010 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
ES | 14.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2011/35] | CZ | 03.11.2010 | |
EE | 03.11.2010 | ||
FI | 03.11.2010 | ||
IE | 03.11.2010 | ||
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
SI | 03.11.2010 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
ES | 14.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2011/33] | FI | 03.11.2010 | |
IE | 03.11.2010 | ||
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
SI | 03.11.2010 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
ES | 14.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2011/30] | FI | 03.11.2010 | |
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
SI | 03.11.2010 | ||
BG | 03.02.2011 | ||
GR | 04.02.2011 | ||
IS | 03.03.2011 | ||
PT | 03.03.2011 | ||
Former [2011/23] | FI | 03.11.2010 | |
LT | 03.11.2010 | ||
LV | 03.11.2010 | ||
IS | 03.03.2011 | ||
Former [2011/20] | LT | 03.11.2010 | Documents cited: | Search | [Y]US5264365 (GEORGIOU GEORGE [US], et al) [Y] 6,7 * siehe das ganze Dokument *; | [A]WO9818946 (GENENTECH INC [US]); | [XY]WO0039323 (GENENCOR INT [US], et al) [X] 1-5,8-10 * siehe das ganze Dokument, insbes. Anspruch 9 * [Y] 6,7; | [X]WO03083125 (GENENCOR INT [US], et al) [X] 1-5,8-10 * siehe das ganze Dokument und z.B. S. 59, Zeile. 26- S. 60; Zeile 7 *; | [A]WO2004035792 (CELLTECH R&D LTD [GB], et al); | [X] - HOENGER A ET AL, "DIRECT IN SITU STRUCTURAL ANALYSIS ANALYSIS OF RECOMBINANT OUTER MEMBRANE PORINS EXPRESSED IN AN OMPA-DEFIECIENT MUTANT ESCHERICHIA COLI STRAIN", JOURNAL OF STRUCTURAL BIOLOGY, ORLANDO, US, (199311), vol. 111, no. 3, ISSN 1047-8477, pages 212 - 221, XP001087991 [X] 1-6,8-10 * siehe Abstrakt * DOI: http://dx.doi.org/10.1006/jsbi.1993.1051 | [XY] - KUJAU M J ET AL, "EXPRESSION AND SECRETION OF FUNCTIONAL MINIANTIBODIES MCPC603SCFVDHIX IN CELL-WALL-LESS L-FORM STRAINS OF PROTEUS MIRABILIS AND ESCHERICHIA COLI: A COMPARISON OF THE SYNTHESIS CAPACITIES OF L-FORM STRAINS WITH AN E. COLI PRODUCER STRAIN", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER VERLAG, BERLIN, DE, (199801), vol. 49, no. 1, ISSN 0175-7598, pages 51 - 58, XP001033433 [X] 1,2,4-6,8-10 * siehe ganzes Dokument * [Y] 3,7 DOI: http://dx.doi.org/10.1007/s002530051136 | [XY] - TIAN HONGPING ET AL, "Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway", JOURNAL OF BACTERIOLOGY, (200201), vol. 184, no. 1, ISSN 0021-9193, pages 111 - 118, XP002466637 [X] 1,2,4-6,8-10 * siehe S. 111, rechte Spalte. * [Y] 3,7 DOI: http://dx.doi.org/10.1128/JB.184.1.111-118.2002 | [X] - MUKHERJEE K J ET AL, "Studies of single-chain antibody expression in quiescent Escherichia coli", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, WASHINGTON,DC, US, (200405), vol. 70, no. 5, ISSN 0099-2240, pages 3005 - 3012, XP002426858 [X] 1,2,4-6,8-10 * siehe ganzes Dokument * DOI: http://dx.doi.org/10.1128/AEM.70.5.3005-3012.2004 | [X] - WAN ET AL, "TolAIII co-overexpression facilitates the recovery of periplasmic recombinant proteins into the growth medium of Escherichia coli", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, US, (199810), vol. 14, no. 1, ISSN 1046-5928, pages 13 - 22, XP000864465 [X] 1,2,4-6,8-10 * siehe S. 14, linke Spalte * DOI: http://dx.doi.org/10.1006/prep.1998.0941 | [A] - TANJI Y ET AL, "EFFECT OF OMPA SIGNAL PEPTIDE MUTATIONS ON OMPA SECRETION SYNTHESIS AND ASSEMBLY", JOURNAL OF BACTERIOLOGY, (1991), vol. 173, no. 6, ISSN 0021-9193, pages 1997 - 2005, XP002466638 | [A] - BANEYX F, "RECOMBINANT PROTEIN EXPRESSION IN ESCHERICHIA COLI", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, (199910), vol. 10, no. 5, ISSN 0958-1669, pages 411 - 421, XP001041299 DOI: http://dx.doi.org/10.1016/S0958-1669(99)00003-8 | [A] - MERGULHAO F J M ET AL, "Recombinant protein secretion in Escherichia coli", BIOTECHNOLOGY ADVANCES, ELSEVIER PUBLISHING, BARKING, GB, (200505), vol. 23, no. 3, ISSN 0734-9750, pages 177 - 202, XP004780594 DOI: http://dx.doi.org/10.1016/j.biotechadv.2004.11.003 | by applicant | KG1005 | EP0448093 | US2008254511 | - CHANG, J. BIOL. CHEM., (1991), vol. 266, pages 10839 - 43 | - SIMMONS ET AL., J. IMMUNOL. METHODS, (2002), vol. 263, pages 133 - 47 |