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EP1897561
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EP About this file: EP1897561
| EP1897561 - Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents [Right-click to bookmark this link] | Status | The application has been refused Status updated on 24.06.2011 Database last updated on 28.05.2024 | Most recent event Tooltip | 24.06.2011 | Refusal of application | published on 27.07.2011 [2011/30] | Applicant(s) | For all designated states ENZON, INC. 20 Kingsbridge Road Piscataway, NJ 08854-3998 / US | [2008/11] | Inventor(s) | 01 /
Greenwald, Richard, B. (deceased) c/o Susan Aldler (legal repr. of deceased) 2730 S. Delaware Ave. Milwaukee, WI 53207 / US | 02 /
Pendri, Annapurna 54 Aspen Drive South Glastonbury, CT 06073 / US | 03 /
Choe, Yun, H. 9 Greenbrier Road Green Brook, NJ 08812 / US | 04 /
Zalipsky, Samuel 1202 Truman Street Redwood City, CA 94061 / US | [2009/39] |
| Former [2008/24] | 01 /
Greenwald, Richard, B. (deceased) c/o Susan Aldler (legal repr. of deceased) 2730 S. Delaware Ave. Milwaukee, WI 53207 / US | ||
| 02 /
Pendri, Annapurna 54 Aspen Drive South Glastonbury, CT 06073 / US | |||
| 03 /
Choe, Yun, H. 9 Greenbrier Road Green Brook, NJ 08812 / US | |||
| Former [2008/11] | 01 /
Greenwald, Richard, B 113 Hickory Road Somerset, NJ 08 / US | ||
| 02 /
Pendri, Annapurna 108 Winston Drive Matawan, NJ 077 / US | |||
| 03 /
Choe, Yun, H. 2 Gemma Court Piscataway, NJ 08854 / US | Representative(s) | Hatzmann, Martin V.O. Johan de Wittlaan 7 2517 JR Den Haag / NL | [N/P] |
| Former [2008/11] | Hatzmann, Martin VEREENIGDE Johan de Wittlaan 7 2517 JR Den Haag / NL | Application number, filing date | 07117973.3 | 14.12.1998 | [2008/11] | Priority number, date | US19970992435 | 17.12.1997 Original published format: US 992435 | US19980183557 | 30.10.1998 Original published format: US 183557 | [2008/11] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP1897561 | Date: | 12.03.2008 | Language: | EN | [2008/11] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 23.11.2007 | Classification | IPC: | A61K47/48, // A61P35/00 | [2008/11] | CPC: |
A61K47/60 (EP,US);
A61P35/00 (EP);
A61P43/00 (EP)
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2008/11] | Extension states | AL | 05.10.2007 | LT | 06.11.2007 | LV | 05.10.2007 | MK | 05.10.2007 | RO | 06.11.2007 | SI | 06.11.2007 | Title | German: | Polymer-Prodrugs amino- und hydroxylhaltiger bioaktiver Wirkstoffe | [2008/11] | English: | Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents | [2008/11] | French: | Promédicament polymères d'agents bioactifs contenant des amines et des hydroxyles | [2008/11] | Examination procedure | 05.10.2007 | Examination requested [2008/11] | 12.08.2008 | Despatch of a communication from the examining division (Time limit: M04) | 09.12.2008 | Reply to a communication from the examining division | 08.02.2011 | Application refused, date of legal effect [2011/30] | 08.02.2011 | Date of oral proceedings | 04.03.2011 | Despatch of communication that the application is refused, reason: substantive examination [2011/30] | 04.03.2011 | Minutes of oral proceedings despatched | Parent application(s) Tooltip | EP98963173.4 / EP1037649 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP19980963173) is 26.04.2005 | Fees paid | Renewal fee | 05.10.2007 | Renewal fee patent year 03 | 05.10.2007 | Renewal fee patent year 04 | 05.10.2007 | Renewal fee patent year 05 | 05.10.2007 | Renewal fee patent year 06 | 05.10.2007 | Renewal fee patent year 07 | 05.10.2007 | Renewal fee patent year 08 | 05.10.2007 | Renewal fee patent year 09 | 05.10.2007 | Renewal fee patent year 10 | 15.12.2008 | Renewal fee patent year 11 | 11.12.2009 | Renewal fee patent year 12 | Penalty fee | Additional fee for renewal fee | 31.12.2010 | 13 M06 Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]JPH06148780 ; | [A]US5093531 (SANO AKIHIKO [JP], et al) [A] * abstract *; | [A]US5349001 (GREENWALD RICHARD B [US], et al) [A] * abstract and reaction scheme bridging columns 8 and 9 *; | [X]EP0648503 (BEHRINGWERKE AG [DE], et al) [X] 1-33 * abstract *; | [A]US5605976 (MARTINEZ ANTHONY J [US], et al) [A] * column 6; example 14 *; | [X] - SENTER P D ET AL, "POLY(ETHYLENE GLYCOL)-DOXURUBICIN CONJUGATES CONTAINING LACTAMASE-SENSITIVE LINKERS", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, (19950701), vol. 6, no. 4, ISSN 1043-1802, pages 389 - 394, XP000517227 [X] 32 * page 389, paragraph joining left- and right-hand columns; figure 1; chart 1 * DOI: http://dx.doi.org/10.1021/bc00034a008 | [Y] - GREENWALD R B, "Drug delivery systems: Anticancer prodrugs and their polymeric conjugates", EXPERT OPINION ON THERAPEUTIC PATENTS 1997 UNITED KINGDOM, (19970606), vol. 7, no. 6, ISSN 1354-3776, pages 601 - 609, XP002296827 [Y] 1-33 * from page 603, left-hand column, last paragraph to page 607, left-hand column, third paragraph * DOI: http://dx.doi.org/10.1517/13543776.7.6.601 | [Y] - CARL L.P. ET AL., "A novel connector linkage applicable in prodrug design", J.MED.CHEM., (1981), vol. 24, no. 5, pages 479 - 480, XP009079818 [Y] 1-33 * schemes I and II; note (3); page 480, right-hand column, lines 9-11 * DOI: http://dx.doi.org/10.1021/jm00137a001 | [YD] - BUNDGAARD H, "THE DOUBLE PRODRUG CONCEPT AND ITS APPLICATIONS", ADVANCED DRUG DELIVERY REVIEWS, AMSTERDAM, NL, (1989), vol. 3, ISSN 0169-409X, pages 39 - 65, XP000606520 [YD] 1-33 * schemes XVII and XVIII on pages 58 and 59; page 59, the first and second paragraphs of section XI.C * DOI: http://dx.doi.org/10.1016/0169-409X(89)90004-5 | [A] - GESSON JP ET AL, "Prodrugs of anthracyclines for chemotherapy via enzyme-monoclonal antibody conjugates", ANTI-CANCER DRUG DESIGN, BASINGSTOKE, GB, (199410), ISSN 0266-9536, XP002076228 [A] * abstract * | [A] - PATENT ABSTRACTS OF JAPAN, (19940824), vol. 0184, no. 54, Database accession no. (P - 1791), & JP06148780 A 19940527 (KONICA CORP) [A] * abstract * | [T] - GREENWALD R B ET AL, "Drug delivery systems employing 1,4- or 1,6-elimination: poly(ethylene glycol) prodrugs of amine-containing compounds", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (199909), vol. 42, ISSN 0022-2623, pages 3657 - 3667, XP002184836 DOI: http://dx.doi.org/10.1021/jm990166e |