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Extract from the Register of European Patents

EP About this file: EP1982716

EP1982716 - NOVEL HISTIDINE DERIVATIVE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.02.2014
Database last updated on 15.07.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
NIPPON ZOKI PHARMACEUTICAL CO. LTD.
1-2, Hiranomachi 2-chome, Chuo-ku Osaka-shi
Osaka 541-0046 / JP
[2008/43]
Inventor(s)01 / NAKAMURA, Ko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
02 / NAKAZAWA, Yoshitaka
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
03 / KAWAMURA, Minoru
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
04 / HIGASHIURA, Kunihiko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
05 / MIURA, Tomoshi
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD
Institute
of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
 [2013/23]
Former [2013/17]01 / NAKAMURA, Ko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
02 / NAKAZAWA, Yoshitaka
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
03 / KAWAMURA, Minoru
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
04 / HIGASHIURA, Kunihiko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institute
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
05 / MIURA, Tomoshi
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD
Institute
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
Former [2013/14]01 / NAKAMURA, Ko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institut
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
02 / NAKAZAWA, Yoshitaka
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institut
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
03 / KAWAMURA, Minoru
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institut
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
04 / HIGASHIURA, Kunihiko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD.
Institut
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
05 / MIURA, Tomoshi
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD
Institut
e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
Former [2008/43]01 / NAKAMURA, Ko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD. Institut e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
02 / NAKAZAWA, Yoshitaka
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD. Institut e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
03 / KAWAMURA, Minoru
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD. Institut e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
04 / HIGASHIURA, Kunihiko
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD. Institut e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
05 / MIURA, Tomoshi
c/o NIPPON ZOKI PHARMACEUTICAL CO., LTD Institut e of Bio-Active Science, 442-1, Kawakitayama
Kinashi, Kato-shi, Hyogo, 673-1461 / JP
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastrasse 30
81925 München / DE
[N/P]
Former [2013/14]HOFFMANN EITLE
Patent- und Rechtsanwälte
Arabellastrasse 4
81925 München / DE
Former [2008/43]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date07707205.623.01.2007
[2008/43]
WO2007JP50942
Priority number, dateJP2006001465624.01.2006         Original published format: JP 2006014656
[2008/43]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007086354
Date:02.08.2007
Language:JA
[2007/31]
Type: A1 Application with search report 
No.:EP1982716
Date:22.10.2008
Language:EN
[2008/43]
Type: B1 Patent specification 
No.:EP1982716
Date:03.04.2013
Language:EN
[2013/14]
Search report(s)International search report - published on:JP02.08.2007
(Supplementary) European search report - dispatched on:EP17.02.2010
ClassificationIPC:A61K31/4172, A61P25/04, C07D233/64
[2008/43]
CPC:
C07D233/64 (EP,KR,US); A61K31/4172 (EP,KR,US); A61P25/04 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/43]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:NEUES HISTIDINDERIVAT[2008/43]
English:NOVEL HISTIDINE DERIVATIVE[2008/43]
French:NOUVEAU DÉRIVÉ D'HISTIDINE[2008/43]
Entry into regional phase12.08.2008Translation filed 
12.08.2008National basic fee paid 
12.08.2008Search fee paid 
12.08.2008Designation fee(s) paid 
12.08.2008Examination fee paid 
Examination procedure12.08.2008Examination requested  [2008/43]
11.05.2010Amendment by applicant (claims and/or description)
18.07.2011Despatch of a communication from the examining division (Time limit: M04)
08.11.2011Reply to a communication from the examining division
23.10.2012Communication of intention to grant the patent
15.02.2013Fee for grant paid
15.02.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.07.2011
Opposition(s)06.01.2014No opposition filed within time limit [2014/11]
Fees paidRenewal fee
28.01.2009Renewal fee patent year 03
26.01.2010Renewal fee patent year 04
25.01.2011Renewal fee patent year 05
24.01.2012Renewal fee patent year 06
18.01.2013Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU23.01.2007
AT03.04.2013
BE03.04.2013
CY03.04.2013
CZ03.04.2013
DK03.04.2013
EE03.04.2013
FI03.04.2013
IT03.04.2013
LT03.04.2013
LV03.04.2013
MC03.04.2013
NL03.04.2013
PL03.04.2013
RO03.04.2013
SE03.04.2013
SI03.04.2013
SK03.04.2013
TR03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
[2016/33]
Former [2016/32]HU23.01.2007
AT03.04.2013
BE03.04.2013
CY03.04.2013
CZ03.04.2013
DK03.04.2013
EE03.04.2013
FI03.04.2013
IT03.04.2013
LT03.04.2013
LV03.04.2013
MC03.04.2013
NL03.04.2013
PL03.04.2013
RO03.04.2013
SE03.04.2013
SI03.04.2013
SK03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2014/38]AT03.04.2013
BE03.04.2013
CY03.04.2013
CZ03.04.2013
DK03.04.2013
EE03.04.2013
FI03.04.2013
IT03.04.2013
LT03.04.2013
LV03.04.2013
MC03.04.2013
NL03.04.2013
PL03.04.2013
RO03.04.2013
SE03.04.2013
SI03.04.2013
SK03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2014/11]AT03.04.2013
BE03.04.2013
CY03.04.2013
CZ03.04.2013
DK03.04.2013
EE03.04.2013
FI03.04.2013
IT03.04.2013
LT03.04.2013
LV03.04.2013
NL03.04.2013
PL03.04.2013
RO03.04.2013
SE03.04.2013
SI03.04.2013
SK03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2014/10]AT03.04.2013
BE03.04.2013
CY03.04.2013
CZ03.04.2013
DK03.04.2013
EE03.04.2013
FI03.04.2013
LT03.04.2013
LV03.04.2013
NL03.04.2013
PL03.04.2013
SE03.04.2013
SI03.04.2013
SK03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2014/09]AT03.04.2013
BE03.04.2013
CY03.04.2013
DK03.04.2013
EE03.04.2013
FI03.04.2013
LT03.04.2013
LV03.04.2013
NL03.04.2013
PL03.04.2013
SE03.04.2013
SI03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2013/52]AT03.04.2013
BE03.04.2013
CY03.04.2013
FI03.04.2013
LT03.04.2013
LV03.04.2013
NL03.04.2013
PL03.04.2013
SE03.04.2013
SI03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2013/50]AT03.04.2013
BE03.04.2013
FI03.04.2013
LT03.04.2013
LV03.04.2013
NL03.04.2013
PL03.04.2013
SE03.04.2013
SI03.04.2013
BG03.07.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2013/49]AT03.04.2013
BE03.04.2013
FI03.04.2013
LT03.04.2013
NL03.04.2013
SE03.04.2013
SI03.04.2013
GR04.07.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2013/48]AT03.04.2013
LT03.04.2013
NL03.04.2013
SI03.04.2013
ES14.07.2013
IS03.08.2013
PT05.08.2013
Former [2013/47]LT03.04.2013
SI03.04.2013
PT05.08.2013
Former [2013/37]SI03.04.2013
Documents cited:Search[A]JPS604172  (HAMARI YAKUHIN KOGYO KK) [A] 1-14 * abstract *;
 [A]US2004242491  (CHANG WILLIAM T H [TW]) [A] 1-14 * abstract ** claims 1-29 *;
 [A]  - ZHAO M ET AL, "New agents for cutaneous photoprotection: derivatives of alpha-amino acids, 4-aminobenzoic and 4-methoxycinnamic acids", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 28, no. 12, ISSN 0223-5234, (19930101), pages 949 - 954, (19930101), XP023870830 [A] 1-14 * page 950; table I; compound 8 *

DOI:   http://dx.doi.org/10.1016/0223-5234(93)90050-O
 [A]  - GARIPCAN B ET AL, "A novel affinity support material for the separation of immunoglobulin G from human plasma", MACROMOLECULAR BIOSCIENCE, WILEY VCH VERLAG, WEINHEIM, DE, vol. 2, no. 3, ISSN 1616-5187, (20020401), pages 135 - 144, (20020320), XP002509544 [A] 1-14 * page 139; figure 3 *

DOI:   http://dx.doi.org/10.1002/1616-5195(20020401)2:3<135::AID-MABI135>3.0.CO;2-8
 [A]  - BENTOLILA A ET AL, "SYNTHESIS AND HEPARIN-LIKE BIOLOGICAL ACTIVITY OF AMINO ACID-BASED POLYMERS", POLYMERS FOR ADVANCED TECHNOLOGIES, WILEY & SONS, BOGNOR REGIS, GB, (20000801), vol. 11, no. 8-12, ISSN 1042-7147, pages 377 - 387, XP000977310 [A] 1-14 * page 381; compound 2g *

DOI:   http://dx.doi.org/10.1002/1099-1581(200008/12)11:8/12<377::AID-PAT985>3.0.CO;2-D
International search[A]JPS59216597  (MICROBIAL CHEM RES FOUND);
 [A]JPH10298197  (ASAHI GLASS CO LTD);
 [AP]JP2006232685  (TOAGOSEI CO LTD);
 [X]  - OHKUBO K. ET AL., "Catalytic activities of novel L-histidyl group-introduced polymers imprinted by a transition state analog in the hydrolysis of amino acid ester", JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL, (1995), vol. 101, no. 2, pages L111 - L114, XP002082390

DOI:   http://dx.doi.org/10.1016/1381-1169(95)00097-6
 [X]  - BENTOLILA A. ET AL., "Poly (N-acryl amino acids): A New Class of Biologically Active Polyanions", JOURNAL OF MEDICINAL CHEMISTRY, (2000), vol. 43, no. 13, pages 2591 - 2600, XP003016044

DOI:   http://dx.doi.org/10.1021/jm000089j
 [X]  - CHO I. ET AL., "Hydrophobic and ionic interactions in the ester hydrolysis by imidazole-containing polymers", BULLETIN OF THE KOREAN CHEMICAL SOCIETY, (1982), vol. 3, no. 1, pages 34 - 36, XP003016045
 [X]  - ZHAO M.J. ET AL., "New agents for cutaneous photoprotection: derivatives of alpha-amino acids, 4-aminobenzoic and 4-methoxycinnamic acids", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, (1993), vol. 28, no. 12, pages 949 - 954, XP003016046

DOI:   http://dx.doi.org/10.1016/0223-5234(93)90050-O
by applicantJPH0641411B
 JPH0797323
 JPH0920660
 JPH0920661
 JP2939301B
 WO0191762
 JP2003267992
    - BROWN, J. H. JONES; J. D. RICHARDS, J. CHEM. SOC. PERKIN TRANS. I, (1982), page 1533
    - KITA ET AL., NIPPON YAKURIGAKU ZASSHI, (1975), vol. 71, pages 195 - 210
    - NIPPON YAKURIGAKU ZASSHI, (1976), vol. 72, pages 573 - 584
    - KIM; CHUNG, PAIN, (1992), vol. 50, pages 355 - 363
    - CHAPLAN ET AL., J. NEUROSá. METHOD, (1994), vol. 53, pages 55 - 63
    - LEE ET AL., J NEUROPHYSIOL., (1999), vol. 81, pages 2226 - 2233
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.