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Extract from the Register of European Patents

EP About this file: EP1978960

EP1978960 - USE OF 6-(3-CHLORO-2-FLUOROBENZYL)-1-Ý(2S)-1-HYDROXY-3-METHYLBUTAN-2-YL ̈-7-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID OR SALT THEREOF FOR TREATING RETROVIRUS INFECTION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.07.2012
Database last updated on 19.03.2026
Most recent event   Tooltip06.07.2012Application deemed to be withdrawnpublished on 08.08.2012  [2012/32]
Applicant(s)For all designated states
Japan Tobacco Inc.
2-1, Toranomon 2-chome, Minato-ku
Tokyo 105-8422 / JP
[2008/42]
Inventor(s)01 / MATSUZAKI, Yuji
c/o Central Pharm. Research Inst. of Japan Tobacco Inc., 1-1, Murasaki-cho
Takatsuki-shi, Osaka 569-1125 / JP
02 / KANO, Mitsuki
c/o Central Pharmaceutical Research Institute of J apan Tobacco Inc., 1-1, Murasaki-cho
Takatsuki-shi, Osaka 569-1125 / JP
03 / IKEDA, Satoru
c/o Central Pharmaceutical Research Institute of J apan Tobacco Inc., 1-1, Murasaki-cho
Takatsuki-shi, Osaka 569-1125 / JP
 [2008/50]
Former [2008/42]01 / MATSUZAKI, Yuji
c/o Central Pharmaceutical Research Institute of J apan Tobacco Inc., 1-1, Murasaki-cho
Takatsuki-shi, Osaka 569-1125 / JP
02 / KANO, Mitsuki
c/o Central Pharmaceutical Research Institute of J apan Tobacco Inc., 1-1, Murasaki-cho
Takatsuki-shi, Osaka 569-1125 / JP
03 / IKEDA, Satoru
c/o Central Pharmaceutical Research Institute of J apan Tobacco Inc., 1-1, Murasaki-cho
Takatsuki-shi, Osaka 569-1125 / JP
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2008/42]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Former [2008/35]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date07713912.901.02.2007
[2008/42]
WO2007JP52159
Priority number, dateUS20060763900P01.02.2006         Original published format: US 763900 P
[2008/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007089030
Date:09.08.2007
Language:EN
[2007/32]
Type: A1 Application with search report 
No.:EP1978960
Date:15.10.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 09.08.2007 takes the place of the publication of the European patent application.
[2008/42]
Search report(s)International search report - published on:JP09.08.2007
(Supplementary) European search report - dispatched on:EP04.11.2009
ClassificationIPC:A61K31/47, A61K31/472, A61K31/506, A61P31/18, C07D215/56
[2008/42]
CPC:
C07D215/56 (EP,US); A61P31/18 (EP); A61P43/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/42]
Extension statesAL15.07.2008
BA15.07.2008
HR15.07.2008
MK15.07.2008
RS15.07.2008
TitleGerman:VERWENDUNG VON 6-(3-CHLOR-2-FLUORBENZYL)-1-[(2S)-1-HYDROXY-3-METHYLBUTAN-2-YL[-7-METHOXY-4-OXO-1,4-DIHYDROCHINOLIN-3-CARBOXYLSÄURE ODER EINEM SALZ DARAUS ZUR BEHANDLUNG EINER RETROVIRENINFEKTION[2008/42]
English:USE OF 6-(3-CHLORO-2-FLUOROBENZYL)-1-Ý(2S)-1-HYDROXY-3-METHYLBUTAN-2-YL ̈-7-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID OR SALT THEREOF FOR TREATING RETROVIRUS INFECTION[2008/42]
French:UTILISATION D'ACIDE 6-(3-CHLORO-2-FLUOROBENZYL)-1-Ý(2S)-1-HYDROXY-3-MÉTHYLBUTAN-2-YL ̈-7-MÉTHOXY-4-OXO-1,4-DIHYDROQUINOLÉINE-3-CARBOXYLIQUE OU D'UN DE SES SELS POUR TRAITER UNE INFECTION RÉTROVIRALE[2008/42]
Entry into regional phase15.07.2008National basic fee paid 
15.07.2008Search fee paid 
15.07.2008Designation fee(s) paid 
15.07.2008Examination fee paid 
Examination procedure17.06.2008Amendment by applicant (claims and/or description)
15.07.2008Examination requested  [2008/42]
09.02.2010Despatch of a communication from the examining division (Time limit: M06)
12.08.2010Reply to a communication from the examining division
29.09.2011Despatch of a communication from the examining division (Time limit: M04)
10.02.2012Application deemed to be withdrawn, date of legal effect  [2012/32]
19.03.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2012/32]
Divisional application(s)EP12154010.8  / EP2452682
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.02.2010
Fees paidRenewal fee
27.02.2009Renewal fee patent year 03
23.02.2010Renewal fee patent year 04
21.02.2011Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
29.02.201206   M06   Not yet paid
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X] US2005288326  (MATSUZAKI YUJI et al.) [X] 1-21 * paragraphs [0026] , [0101] , [0108] , [0109] *
International search[Y]   KOH Y. ET AL.: "Advances in the development of antiretroviral therapy", ANTIBIOTICS & CHEMOTHERAPY, vol. 20, no. 7, 2004, pages 1038 - 1048, XP003015875
 [Y]   AMANO M. ET AL.: "Recent development of new drugs against HIV-1 infection", IGAKU NO AYUMI, vol. 213, no. 10, 2005, pages 891 - 900, XP003015876
 [Y]   BEALE K.K. ET AL.: "Combinations of reverse transcriptase, protease and integrase inhibitors can be synergistic in vitro against drug-sensitive and RT inhibitor-resistant molecular clones of HIV-1", ANTIVIRAL RESEARCH, vol. 46, no. 3, 2000, pages 223 - 232, XP001027294

DOI:   http://dx.doi.org/10.1016/S0166-3542(00)00083-8
 [Y]   SUGIURA W. ET AL.: "Genome and drug resistance of HIV", GENDAI IRYO, vol. 34, no. 5, 2002, pages 1135 - 1141, XP003015877
by applicant  MARSH; HELENIUS, ADV. VIRAL RES., vol. 36, 1989, pages 107 - 151
   GILBOA ET AL., CELL, vol. 18, 1979, pages 93 - 100
   BROWN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 2525 - 2529
   FUJIWARA; MIZUUCHI, CELL, vol. 54, 1988, pages 497 - 504
   BARRE-SINOSSI ET AL., SCIENCE, vol. 220, 1983, pages 868 - 870
   DALGLEISH ET AL., NATURE, vol. 312, 1984, pages 767 - 768
   MADDON ET AL., CELL, vol. 47, 1986, pages 333 - 48
   AIDS EPIDEMIC UPDATE, December 2005 (2005-12-01), pages 76 - 80
   GALLO, SCIENCE, vol. 224, 1984, pages 500 - 503
   CLAVEL ET AL., SCIENCE, vol. 223, 1986, pages 343 - 346
   JONASSEN ET AL., VIROL., vol. 231, 1997, pages 43 - 47
   BLOOM, SCIENCE, vol. 272, 1996, pages 1888 - 1900
   LAFEUILLADE ET AL., J. INFECT. DIS., vol. 175, 1997, pages 1051 - 55
   VELLA; FLORIDIA, INTERNATIONAL AIDS SOCIETY USA, vol. 4, no. 3, 1996, pages 15
   CONDRA ET AL., NATURE, vol. 374, 1995, pages 569 - 71
   MYERS; MONTANER: "The Retroviridae", vol. 1, 1992, PLENUM PRESS, pages: 51 - 105
   CONDRA ET AL., NATURE, vol. 374, 1995, pages 569 - 571
   D'AQUILA ET AL., TOPICS IN HIV MEDICINE, vol. 11, 2003, pages 92 - 96
   KELLAM; LARDER, ANTIMICROB. AGENTS CHEMOTHERAP., vol. 38, 1994, pages 23 - 30
   HERTOGS ET AL., ANTIMICROB. AGENTS CHEMOTHERAP., vol. 42, 1998, pages 269 - 276
   PAUWELS ET AL., J. VIRAL METHODS, vol. 20, 1988, pages 309 - 321
   GENNARO ET AL.: "Remington's Pharmaceutical Sciences", 1990, MACK PUBLISHING CO.
   PETROPOULUS ET AL., ANTIMICROB. AGENTS CHEMOTHER., vol. 44, 2000, pages 920 - 928
   BUCKHEIT ET AL., AIDS RESEARCH AND HUMAN RETROVIRUSES, vol. 7, 1991, pages 295 - 302
   WEISLOW ET AL., J. NATL. CANCER INST., vol. 81, 1989, pages 577 - 586
   ROEHM ET AL., J. IMMUNOL. METHODS, vol. 142, 1991, pages 257 - 265
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.