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Extract from the Register of European Patents

EP About this file: EP1984400

EP1984400 - REGULATORS OF NFAT [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.10.2013
Database last updated on 19.10.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU, LU		published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
Immune Disease Institute, Inc.
800 Huntington Avenue
Boston, MA 02115 / US
[2008/44]
Inventor(s)01 / RAO, Anjana
19 Agassiz Street
Cambridge, MA 02140 / US
02 / FESKE, Stefan
564 1st Avenue
22J
New York, NY 10016 / US
03 / HOGAN, Patrick
19 Agassiz Street
Cambridge, MA 02140 / US
04 / GWACK, Yousang
923 Levering Ave.No. 502
Los Angeles, CA 90024 / US
 [2012/48]
Former [2008/46]01 / RAO, Anjana
19 Agassiz Street
Cambridge, MA 02140 / US
02 / FESKE, Stefan
564 1st Avenue 22J
New York, NY 10016 / US
03 / HOGAN, Patrick
19 Agassiz Street
Cambridge, MA 02140 / US
04 / GWACK, Yousang
923 Levering Ave.No. 502
Los Angeles, CA 90024 / US
Former [2008/44]01 / RAO, Anjana
19 Agassiz Street
Cambridge, MA 02140 / US
02 / FESKE, Stefan
564 1st Avenue 22J
New York, NY 10016 / US
03 / HOGAN, Patrick
19 Agassiz Street
Cambridge, MA 02140 / US
04 / GWACK, Yousang
923 Levering Ave.2No. 502
Los Angeles, CA 90024 / US
Representative(s)Brown, David Leslie
Haseltine Lake Kempner LLP
Redcliff Quay
120 Redcliff Street
Bristol BS1 6HU / GB
[N/P]
Former [2012/48]Brown, David Leslie
Haseltine Lake LLP Redcliff Quay 120 Redcliff Street Bristol
BS1 6HU / GB
Former [2008/44]Brown, David Leslie
HASELTINE LAKE Redcliff Quay 120 Redcliff Street
Bristol BS1 6HU / GB
Application number, filing date07717846.505.01.2007
[2008/44]
WO2007US00280
Priority number, dateUS20060756934P05.01.2006         Original published format: US 756934 P
[2008/44]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007081804
Date:19.07.2007
Language:EN
[2007/29]
Type: A2 Application without search report 
No.:EP1984400
Date:29.10.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 19.07.2007 takes the place of the publication of the European patent application.
[2008/44]
Type: B1 Patent specification 
No.:EP1984400
Date:28.11.2012
Language:EN
[2012/48]
Search report(s)International search report - published on:EP06.03.2008
ClassificationIPC:C07K16/18
[2008/44]
CPC:
G01N33/5041 (EP,US); C07K14/4702 (US); C07K16/18 (EP,US);
A61K35/12 (US); C07H21/04 (EP,US); C12N15/63 (EP,US);
C12N15/907 (US); C12N2510/00 (US); C12N5/16 (US);
C12Q1/00 (US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/44]
TitleGerman:REGULATOREN VON NFAT[2008/44]
English:REGULATORS OF NFAT[2008/44]
French:RÉGULATEURS DE NFAT[2008/44]
Entry into regional phase30.07.2008National basic fee paid 
30.07.2008Designation fee(s) paid 
30.07.2008Examination fee paid 
Examination procedure04.08.2008Amendment by applicant (claims and/or description)
04.08.2008Examination requested  [2008/44]
19.11.2008Despatch of a communication from the examining division (Time limit: M06)
05.06.2009Reply to a communication from the examining division
13.04.2010Despatch of a communication from the examining division (Time limit: M06)
19.11.2010Reply to a communication from the examining division
01.03.2012Cancellation of oral proceeding that was planned for 02.03.2012
02.03.2012Date of oral proceedings (cancelled)
20.06.2012Communication of intention to grant the patent
17.10.2012Fee for grant paid
17.10.2012Fee for publishing/printing paid
Divisional application(s)EP10191986.8  / EP2368912
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  19.11.2008
Opposition(s)29.08.2013No opposition filed within time limit [2013/45]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
08.06.2009Request for further processing filed
08.06.2009Full payment received (date of receipt of payment)
Request granted
30.07.2009Decision despatched
Fees paidRenewal fee
28.01.2009Renewal fee patent year 03
13.01.2010Renewal fee patent year 04
14.01.2011Renewal fee patent year 05
11.01.2012Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU05.01.2007
AT28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
RO28.11.2012
SI28.11.2012
SK28.11.2012
LU05.01.2013
MC31.01.2013
BG28.02.2013
GB28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
[2015/34]
Former [2014/09]AT28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
RO28.11.2012
SI28.11.2012
SK28.11.2012
MC31.01.2013
BG28.02.2013
GB28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/37]AT28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
RO28.11.2012
SI28.11.2012
SK28.11.2012
MC31.01.2013
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/35]AT28.11.2012
CY28.11.2012
CZ28.11.2012
DK28.11.2012
EE28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SI28.11.2012
SK28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/34]AT28.11.2012
CY28.11.2012
DK28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SI28.11.2012
BG28.02.2013
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/31]AT28.11.2012
CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SI28.11.2012
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/28]CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SI28.11.2012
GR01.03.2013
ES11.03.2013
PT28.03.2013
Former [2013/26]CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
SI28.11.2012
GR01.03.2013
ES11.03.2013
Former [2013/24]CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
GR01.03.2013
ES11.03.2013
Former [2013/23]CY28.11.2012
FI28.11.2012
LT28.11.2012
LV28.11.2012
PL28.11.2012
ES11.03.2013
Former [2013/22]FI28.11.2012
LT28.11.2012
ES11.03.2013
Former [2013/20]LT28.11.2012
Cited inInternational search[X]EP0976823  (VOELKEL HELGE [DE]) [X] 1,9-11,34,39,43,45,46 * claim - *;
 [PX]  - FESKE STEFAN ET AL, "A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.", NATURE 11 MAY 2006, (20060511), vol. 441, no. 7090, ISSN 1476-4687, pages 179 - 185, XP002449671 [PX] 1-48 * the whole document *

DOI:   http://dx.doi.org/10.1038/nature04702
 [PX]  - GWACK YOUSANG ET AL, "A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT.", NATURE 1 JUN 2006, (20060601), vol. 441, no. 7093, ISSN 1476-4687, pages 646 - 650, XP002449672 [PX] 1-48 * the whole document *

DOI:   http://dx.doi.org/10.1038/nature04631
 [A]  - FESKE STEFAN ET AL, "A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients.", THE JOURNAL OF EXPERIMENTAL MEDICINE 5 SEP 2005, (20050905), vol. 202, no. 5, ISSN 0022-1007, pages 651 - 662, XP009089122 [A] * the whole document *

DOI:   http://dx.doi.org/10.1084/jem.20050687
 [A]  - FESKE S ET AL, "Gene regulation mediated by calcium signals in T lymphocytes.", NATURE IMMUNOLOGY APR 2001, (200104), vol. 2, no. 4, ISSN 1529-2908, pages 316 - 324, XP009089127

DOI:   http://dx.doi.org/10.1038/86318
 [A]  - CRABTREE GERALD R ET AL, "NFAT signaling: choreographing the social lives of cells.", CELL APR 2002, (200204), vol. 109 Suppl, ISSN 0092-8674, pages S67 - S79, XP009089126

DOI:   http://dx.doi.org/10.1016/S0092-8674(02)00699-2
 [A]  - IM SIN-HYEOG ET AL, "Activation and deactivation of gene expression by Ca2+/calcineurin-NFAT-mediated signaling.", MOLECULES AND CELLS 31 AUG 2004, (20040831), vol. 18, no. 1, ISSN 1016-8478, pages 1 - 9, XP009089136
 [A]  - LIU J, "FK506 and ciclosporin: molecular probes for studying intracellular signal transduction.", TRENDS IN PHARMACOLOGICAL SCIENCES MAY 1993, (199305), vol. 14, no. 5, ISSN 0165-6147, pages 182 - 188, XP009089118
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.