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Extract from the Register of European Patents

EP About this file: EP1976850

EP1976850 - NOVEL LANTHANIDE LIGANDS AND COMPLEXES, AND USE THEREOF AS CONTRAST AGENTS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.06.2013
Database last updated on 15.06.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU, LU		published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
COMMISSARIAT A L'ENERGIE ATOMIQUE
25, rue Leblanc Immeuble "Le Ponant D"
75015 Paris / FR
[2008/41]
Inventor(s)01 / GATEAU, Christelle
11 Cité du Coût
F-38560 Champ sur Drac / FR
02 / MAZZANTI, Marinella
1535 Chemin du Canet
F-38950 St Martin Le Vinoux / FR
03 / NONAT, Aline
7, rue de Closeau
F-21380 EPAGNY / FR
 [2009/08]
Former [2008/41]01 / GATEAU, Christelle
11 Cité du Coût
F-38560 Champ sur Drac / FR
02 / MAZZANTI, Marinella
1535 Chemin du Canet
F-38950 St Martin Le Vinoux / FR
03 / NONAT, Aline
16 rue Doyen Gosse
F-38600 Fontaine / FR
Representative(s)Boubal, Denis Henri Jacques, et al
Bureau Duthoit Legros Associés
31, rue des Poissonceaux
CS 40009
59044 Lille Cedex / FR
[N/P]
Former [2011/16]Boubal, Denis Henri Jacques, et al
Bureau Duthoit Legros Associés 96/98, Boulevard Carnot B.P. 105
59027 Lille Cedex / FR
Former [2008/41]Duthoit, Michel Georges André
Bureau Duthoit Legros Associés, 96/98, Boulevard Carnot, B.P. 105
59027 Lille Cedex / FR
Application number, filing date07718058.619.01.2007
[2008/41]
WO2007FR00109
Priority number, dateFR2006000053120.01.2006         Original published format: FR 0600531
[2008/41]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2007083036
Date:26.07.2007
Language:FR
[2007/30]
Type: A1 Application with search report 
No.:EP1976850
Date:08.10.2008
Language:FR
The application published by WIPO in one of the EPO official languages on 26.07.2007 takes the place of the publication of the European patent application.
[2008/41]
Type: B1 Patent specification 
No.:EP1976850
Date:15.08.2012
Language:FR
[2012/33]
Search report(s)International search report - published on:EP26.07.2007
ClassificationIPC:C07D401/14, G01N33/532, A61K49/10
[2008/41]
CPC:
C07D401/14 (EP,US); A61K49/103 (EP,US); A61P43/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/41]
Extension statesAL04.07.2008
BA04.07.2008
HR04.07.2008
MK04.07.2008
RS08.07.2008
TitleGerman:NEUARTIGE LANTHANIDLIGANDEN UND -KOMPLEXE SOWIE IHRE ANWENDUNG ALS KONTRASTMITTEL[2008/41]
English:NOVEL LANTHANIDE LIGANDS AND COMPLEXES, AND USE THEREOF AS CONTRAST AGENTS[2008/41]
French:NOUVEAUX LIGANDS ET COMPLEXES DE LANTHANIDES, ET LEUR UTILISATION EN TANT QU'AGENTS DE CONTRASTE[2008/41]
Entry into regional phase04.07.2008National basic fee paid 
04.07.2008Designation fee(s) paid 
04.07.2008Examination fee paid 
Examination procedure04.07.2008Examination requested  [2008/41]
05.11.2008Despatch of a communication from the examining division (Time limit: M06)
29.04.2009Reply to a communication from the examining division
30.01.2012Cancellation of oral proceeding that was planned for 07.02.2012
07.02.2012Date of oral proceedings (cancelled)
26.03.2012Communication of intention to grant the patent
03.07.2012Fee for grant paid
03.07.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  05.11.2008
Opposition(s)16.05.2013No opposition filed within time limit [2013/30]
Fees paidRenewal fee
08.01.2009Renewal fee patent year 03
24.12.2009Renewal fee patent year 04
31.01.2011Renewal fee patent year 05
25.01.2012Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.01.2007
AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
TR15.08.2012
BG15.11.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
IE19.01.2013
LU19.01.2013
BE31.01.2013
CH31.01.2013
LI31.01.2013
MC31.01.2013
[2015/34]
Former [2015/32]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
TR15.08.2012
BG15.11.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
IE19.01.2013
BE31.01.2013
CH31.01.2013
LI31.01.2013
MC31.01.2013
Former [2014/07]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
BG15.11.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
IE19.01.2013
BE31.01.2013
CH31.01.2013
LI31.01.2013
MC31.01.2013
Former [2013/49]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
BG15.11.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
BE31.01.2013
CH31.01.2013
LI31.01.2013
MC31.01.2013
Former [2013/48]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
BG15.11.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
CH31.01.2013
LI31.01.2013
MC31.01.2013
Former [2013/37]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
BG15.11.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
MC31.01.2013
Former [2013/34]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
BG15.11.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
Former [2013/23]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
IT15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
RO15.08.2012
SE15.08.2012
SI15.08.2012
SK15.08.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
Former [2013/22]AT15.08.2012
CY15.08.2012
CZ15.08.2012
DK15.08.2012
EE15.08.2012
FI15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
SE15.08.2012
SI15.08.2012
GR16.11.2012
ES26.11.2012
IS15.12.2012
PT17.12.2012
Former [2013/21]AT15.08.2012
CY15.08.2012
DK15.08.2012
FI15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
SE15.08.2012
SI15.08.2012
GR16.11.2012
IS15.12.2012
PT17.12.2012
Former [2013/15]AT15.08.2012
CY15.08.2012
FI15.08.2012
LT15.08.2012
LV15.08.2012
NL15.08.2012
PL15.08.2012
SE15.08.2012
SI15.08.2012
GR16.11.2012
IS15.12.2012
PT17.12.2012
Former [2013/13]AT15.08.2012
CY15.08.2012
FI15.08.2012
LT15.08.2012
LV15.08.2012
PL15.08.2012
SE15.08.2012
SI15.08.2012
GR16.11.2012
IS15.12.2012
PT17.12.2012
Former [2013/12]AT15.08.2012
CY15.08.2012
FI15.08.2012
LT15.08.2012
LV15.08.2012
PL15.08.2012
SE15.08.2012
SI15.08.2012
GR16.11.2012
IS15.12.2012
Former [2013/11]AT15.08.2012
CY15.08.2012
FI15.08.2012
LT15.08.2012
LV15.08.2012
PL15.08.2012
SI15.08.2012
GR16.11.2012
IS15.12.2012
Former [2013/10]AT15.08.2012
CY15.08.2012
FI15.08.2012
LT15.08.2012
IS15.12.2012
Former [2013/09]AT15.08.2012
FI15.08.2012
LT15.08.2012
Former [2013/08]AT15.08.2012
LT15.08.2012
Former [2013/07]AT15.08.2012
Cited inInternational search[Y]WO2005021538  (WALLAC OY [FI], et al) [Y] 1-14 * Revendications 1-23; composés 32,33a-33b,34a-34b,48-50 *;
 [Y]JP2005187546  (KANSAI TLO KK) [Y] 1-14 * Composés 17 et 44 *;
 [Y]  - TAKALO H ET AL, "SYNTHESIS AND LUMINESCENCE OF NOVEL EUIII COMPLEXING AGENTS AND LABELS WITH 4-(PHENYLETHYNYL)PYRIDINE SUBUNITS", HELVETICA CHIMICA ACTA, VERLAG HELVETICA CHIMICA ACTA. BASEL, CH, (1996), vol. 79, no. 3, ISSN 0018-019X, pages 789 - 802, XP001002467 [Y] 1-14 * Composé 24 *

DOI:   http://dx.doi.org/10.1002/hlca.19960790321
 [Y]  - C. GATEAU ET AL., "Solid-state and soltuion properties of the lanthanide complexes of a new nonadentate tripodal ligand derived from 1,4,7-triazacyclononane", DALTON TRANS., (2003), pages 2428 - 2433, XP002402552 [Y] 1-14 * Schéma 1, H3tpatcn *
 [Y]  - M. MAGERSTÄDT ET AL., "Gd(DOTA): An alternative to Gd(DTPA) as a T1,2 relaxation agent for NMR imaging or spectroscopy", MAGNETIC RESONANCE IN MEDICINE, (1986), vol. 3, no. 5, pages 808 - 812, XP009073651 [Y] 1-14 * Table 1 *
 [PX]  - A. NONAT ET AL., "Lanthanide Complexes of a Picolinate Ligand Derived from 1,4,7-Triazacyclononane with Potential Application in Magnetic Resonance Imaging and Time-Resolved Luminescence Imaging", CHEM. EUR. J., (20060606), vol. 12, pages 7133 - 7150, XP002434539 [PX] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1002/chem.200501390
by applicant   - G. C. GERALDES; M. C. ALPOIM; M. P. M. MARQUES; A. D. SHERRY; M. SINGH, INORG. CHEM, (1985), vol. 24, pages 3876 - 3881
    - B. ALPHA; V. BALZANI; J.-M. LEHN; S. PERATHONER; N. SABBATINI, ANGEW. CHEM. INT. ED. ENGT., (1987), vol. 26, page 1266
    - G. MATHIS, CLIN. CHEM., (1993), vol. 39, page 195
    - GEORGE; J. A. WEINSTEIN; C. WILSON; M. SCHRÔDER, DALTON TRANS, (2003), pages 1693 - 1700
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.