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Extract from the Register of European Patents

EP About this file: EP2018368

EP2018368 - MALONAMIDE DERIVATIVES AS GAMMA SECRETASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.10.2013
Database last updated on 26.03.2026
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU, LU		published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2009/05]For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
Inventor(s)01 / FLOHR, Alexander
Passwangstrasse 3
CH-4153 Reinach Bl / CH
02 / JAKOB-ROETNE, Roland
Oberer Baselblick 37
79594 Inzlingen / DE
03 / WOSTL, Wolfgang
Im Strick 2
79639 Grenzach-Wyhlen / DE
 [2009/05]
Representative(s)Klein, Thomas
F. Hoffmann-La Roche AG
Patent Department
Grenzacherstrasse 124
4070 Basel / CH
[N/P]
Former [2012/34]Klein, Thomas
F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124
4070 Basel / CH
Former [2009/29]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Former [2009/05]Bastian, Werner Maria
Vossius & Partner Siebertstrasse 4
81675 München / DE
Application number, filing date07727035.319.03.2007
[2009/05]
WO2007EP52557
Priority number, dateEP2006011177127.03.2006         Original published format: EP 06111771
[2009/05]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2007110335
Date:04.10.2007
Language:EN
[2007/40]
Type: A1 Application with search report 
No.:EP2018368
Date:28.01.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 04.10.2007 takes the place of the publication of the European patent application.
[2009/05]
Type: B1 Patent specification 
No.:EP2018368
Date:05.12.2012
Language:EN
[2012/49]
Search report(s)International search report - published on:EP04.10.2007
ClassificationIPC:C07D223/18, A61K31/55, A61P25/28
[2009/05]
CPC:
C07D223/18 (EP,KR,US); A61K31/55 (KR); A61P25/28 (EP);
A61P43/00 (EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/05]
TitleGerman:MALONAMIDDERIVATE ALS GAMMASEKRETASE-INHIBITOREN[2009/05]
English:MALONAMIDE DERIVATIVES AS GAMMA SECRETASE INHIBITORS[2009/05]
French:DÉRIVÉS DE MALONAMIDE EN TANT QU'INHIBITEURS DE LA GAMMA SECRÉTASE[2009/05]
Entry into regional phase27.10.2008National basic fee paid 
27.10.2008Designation fee(s) paid 
27.10.2008Examination fee paid 
Examination procedure19.09.2007Request for preliminary examination filed
International Preliminary Examining Authority: EP
27.10.2008Examination requested  [2009/05]
22.03.2010Despatch of a communication from the examining division (Time limit: M04)
30.07.2010Reply to a communication from the examining division
23.04.2012Communication of intention to grant the patent
03.09.2012Fee for grant paid
03.09.2012Fee for publishing/printing paid
11.10.2012Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.03.2010
Opposition(s)06.09.2013No opposition filed within time limit [2013/46]
Request for further processing for:The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent
19.10.2012Request for further processing filed
19.10.2012Full payment received (date of receipt of payment)
Request granted
06.11.2012Decision despatched
Fees paidRenewal fee
06.03.2009Renewal fee patent year 03
08.03.2010Renewal fee patent year 04
10.03.2011Renewal fee patent year 05
07.03.2012Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.03.2007
AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
DK05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
MT05.12.2012
NL05.12.2012
PL05.12.2012
RO05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
IE19.03.2013
LU19.03.2013
MC31.03.2013
IS05.04.2013
PT05.04.2013
[2015/34]
Former [2014/32]AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
DK05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
MT05.12.2012
NL05.12.2012
PL05.12.2012
RO05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
IE19.03.2013
MC31.03.2013
IS05.04.2013
PT05.04.2013
Former [2014/07]AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
DK05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
NL05.12.2012
PL05.12.2012
RO05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
IE19.03.2013
MC31.03.2013
IS05.04.2013
PT05.04.2013
Former [2013/48]AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
DK05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
NL05.12.2012
PL05.12.2012
RO05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
MC31.03.2013
IS05.04.2013
PT05.04.2013
Former [2013/47]AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
NL05.12.2012
PL05.12.2012
RO05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
MC31.03.2013
IS05.04.2013
PT05.04.2013
Former [2013/40]AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
NL05.12.2012
PL05.12.2012
RO05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
IS05.04.2013
PT05.04.2013
Former [2013/37]AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
NL05.12.2012
PL05.12.2012
RO05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
IS05.04.2013
Former [2013/35]AT05.12.2012
BE05.12.2012
CY05.12.2012
CZ05.12.2012
EE05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
PL05.12.2012
SE05.12.2012
SI05.12.2012
SK05.12.2012
BG05.03.2013
GR06.03.2013
IS05.04.2013
Former [2013/34]AT05.12.2012
BE05.12.2012
CY05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
PL05.12.2012
SE05.12.2012
SI05.12.2012
BG05.03.2013
GR06.03.2013
IS05.04.2013
Former [2013/33]AT05.12.2012
BE05.12.2012
CY05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
PL05.12.2012
SE05.12.2012
SI05.12.2012
GR06.03.2013
Former [2013/31]AT05.12.2012
CY05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
PL05.12.2012
SE05.12.2012
SI05.12.2012
GR06.03.2013
Former [2013/26]CY05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
PL05.12.2012
SE05.12.2012
SI05.12.2012
GR06.03.2013
Former [2013/24]CY05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
PL05.12.2012
SE05.12.2012
GR06.03.2013
Former [2013/23]CY05.12.2012
FI05.12.2012
LT05.12.2012
LV05.12.2012
PL05.12.2012
SE05.12.2012
Former [2013/22]FI05.12.2012
LT05.12.2012
SE05.12.2012
Former [2013/21]LT05.12.2012
SE05.12.2012
Former [2013/20]LT05.12.2012
Cited inby applicant  SCIENCE, vol. 297, July 2002 (2002-07-01), pages 353 - 356
   JOURN. OF MEDICINAL CHEMISTRY, vol. 44, no. 13, 2001, pages 2039 - 2060
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.