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Extract from the Register of European Patents

EP About this file: EP2027290

EP2027290 - PREDICTIVE GENE EXPRESSION PATTERN FOR COLORECTAL CARCINOMAS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.08.2012
Database last updated on 16.09.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
Friedrich-Alexander-Universität Erlangen-Nürnberg
Schlossplatz 4
91054 Erlangen / DE
[2009/09]
Inventor(s)01 / CRONER, Roland
Gartenstrasse 2
91341 Roettenbach / DE
02 / HOHENBERGER, Werner
Am Gruendle 23
91074 Herzogenaurach / DE
03 / REINGRUBER, Bertram
Benediktusweg 22
93049 Regensburg / DE
04 / LAUSEN, Berthold
Altstaedterkirchenplatz 2
91084 Erlangen / DE
 [2009/16]
Former [2009/09]01 / CRONER, Roland
Gartenstrasse 2
91341 Roettenbach / DE
02 / HOHENBERGER, Werner
Am Gruendle 23
91074 Herzogenaurach / DE
03 / REINGRUBER, Bertram
Tulgenstrasse 5
90542 Eckental / DE
04 / LAUSEN, Berthold
Altstaedterkirchenplatz 2
91084 Erlangen / DE
Representative(s)Isarpatent
Patent- und Rechtsanwälte Barth
Charles Hassa Peckmann & Partner mbB
Postfach 44 01 51
80750 München / DE
[N/P]
Former [2012/18]Isarpatent
Patent- und Rechtsanwälte
Postfach 44 01 51
80750 München / DE
Former [2011/40]Sandmann, Wolfgang
Reinhard, Skuhra, Weise & Partner GbR Patent- und Rechtsanwälte Friedrichstrasse 31
80801 München / DE
Former [2009/09]Sandmann, Wolfgang
Reinhard, Skuhra, Weise & Partner GbR Patent- und Rechtsanwälte Friedrichstrasse 31
80801 München / DE
Application number, filing date07729452.823.05.2007
[2009/09]
WO2007EP55017
Priority number, dateDE2006102441624.05.2006         Original published format: DE102006024416
[2009/09]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report
No.:WO2007135174
Date:29.11.2007
Language:DE
[2007/48]
Type: A1 Application with search report 
No.:EP2027290
Date:25.02.2009
Language:DE
The application published by WIPO in one of the EPO official languages on 29.11.2007 takes the place of the publication of the European patent application.
[2009/09]
Type: B1 Patent specification 
No.:EP2027290
Date:05.10.2011
Language:DE
[2011/40]
Search report(s)International search report - published on:EP29.11.2007
ClassificationIPC:C12Q1/68
[2009/09]
CPC:
C12Q1/6886 (EP,US); A61P35/00 (EP); C12Q1/6837 (EP,US);
C12Q2600/112 (EP,US); C12Q2600/118 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/09]
TitleGerman:PRAEDIKTIVES GENEXPRESSIONSMUSTER FUER KOLOREKTALE KARZINOME[2009/09]
English:PREDICTIVE GENE EXPRESSION PATTERN FOR COLORECTAL CARCINOMAS[2009/09]
French:MODÈLE D'EXPRESSION GÉNIQUE PRÉDICTIF POUR LE CANCER COLORECTAL[2009/09]
Entry into regional phase19.11.2008National basic fee paid 
19.11.2008Designation fee(s) paid 
19.11.2008Examination fee paid 
Examination procedure19.03.2008Request for preliminary examination filed
International Preliminary Examining Authority: EP
19.11.2008Amendment by applicant (claims and/or description)
19.11.2008Examination requested  [2009/09]
23.04.2009Despatch of a communication from the examining division (Time limit: M04)
08.07.2009Reply to a communication from the examining division
18.03.2011Date of oral proceedings
20.04.2011Minutes of oral proceedings despatched
03.05.2011Communication of intention to grant the patent
16.08.2011Fee for grant paid
16.08.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.04.2009
Opposition(s)06.07.2012No opposition filed within time limit [2012/37]
Fees paidRenewal fee
29.05.2009Renewal fee patent year 03
30.03.2010Renewal fee patent year 04
11.05.2011Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU23.05.2007
CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
MT05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
TR05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
AT23.05.2012
LU23.05.2012
BE31.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
[2014/34]
Former [2014/27]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
MT05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
TR05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
AT23.05.2012
LU23.05.2012
BE31.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2014/21]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
MT05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
TR05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
AT23.05.2012
BE31.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/36]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
MT05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
AT23.05.2012
BE31.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/35]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
MT05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
BE31.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/29]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
FI05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
BE31.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/23]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
BE31.05.2012
CH31.05.2012
FR31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/22]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
ES16.01.2012
IS05.02.2012
PT06.02.2012
BE31.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/12]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
BE31.05.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/07]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
CH31.05.2012
LI31.05.2012
MC31.05.2012
Former [2013/03]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
MC31.05.2012
Former [2012/37]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
IT05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
PL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/36]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
RO05.10.2011
SE05.10.2011
SI05.10.2011
SK05.10.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/35]CY05.10.2011
CZ05.10.2011
DK05.10.2011
EE05.10.2011
IE05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
BG05.01.2012
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/34]CY05.10.2011
CZ05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/28]CY05.10.2011
LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/24]LT05.10.2011
LV05.10.2011
NL05.10.2011
SE05.10.2011
SI05.10.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/23]LT05.10.2011
NL05.10.2011
SI05.10.2011
GR06.01.2012
IS05.02.2012
PT06.02.2012
Former [2012/21]LT05.10.2011
SI05.10.2011
IS05.02.2012
Former [2012/20]LT05.10.2011
SI05.10.2011
Former [2012/11]SI05.10.2011
Cited inInternational search[A]  - GREENBAUM D ET AL, "COMPARING PROTEIN ABUNDANCE AND MRNA EXPRESSION LEVELS ON A GENOMIC SCALE", GENOME BIOLOGY (ONLINE), GB, (2003), vol. 40, no. 9, ISSN 1465-6914, pages 11701 - 11708, XP008036618 [A] 15,16 * page 4, column L - page 5, column R; figure 1 *
 [A]  - GREENBAUM D ET AL, "Interrelating different types of genomic data, from proteome to secretome: 'oming in on function.", GENOME RESEARCH SEP 2001, (200109), vol. 11, no. 9, ISSN 1088-9051, pages 1463 - 1468, XP009088703 [A] 15,16 * page 1467, column R - page 1467, column L; figure 2a *

DOI:   http://dx.doi.org/10.1101/gr.207401
 [A]  - OERNTOFT T F ET AL, "GENOME-WIDE STUDY OF GENE COPY NUMBERS, TRANSCRIPTS, AND PROTEIN LEVELS IN PAIRS OF NON-INVASIVE AND INVASIVE HUMAN TRANSITIONAL CELL CARCINOMAS", MOLECULAR AND CELLULAR PROTEOMICS, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (2002), vol. 1, no. 1, ISSN 1535-9476, pages 37 - 45, XP008015037 [A] 15,16 * page 44, column R *

DOI:   http://dx.doi.org/10.1074/mcp.M100019-MCP200
 [A]  - CELIS A J E ET AL, "Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, (20000825), vol. 480, no. 1, ISSN 0014-5793, pages 2 - 16, XP004337487 [A] 15,16 * page 13, column L *

DOI:   http://dx.doi.org/10.1016/S0014-5793(00)01771-3
 [X]  - CRONER ROLAND S ET AL, "Microarray versus conventional prediction of lymph node metastasis in colorectal carcinoma.", CANCER 15 JUL 2005, (20050715), vol. 104, no. 2, ISSN 0008-543X, pages 395 - 404, XP009088697 [X] 1,2,6-8,10-12,14 * the whole document *

DOI:   http://dx.doi.org/10.1002/cncr.21170
 [A]  - LI M ET AL, "GENES ASSOCIATED WITH LIVER METASTASIS OF COLON CANCER, IDENTIFIED BY GENOME-WIDE CDNA MICROARRAY", INTERNATIONAL JOURNAL OF ONCOLOGY, EDITORIAL ACADEMY OF THE INTERNATIONAL JOURNAL OF ONCOLOGY,, GR, (200402), vol. 24, no. 2, ISSN 1019-6439, pages 305 - 312, XP009027443 [A] 1-14 * the whole document *
 [A]  - FREDERIKSEN CASPER MOLLER ET AL, "Classification of Dukes' B and C colorectal cancers using expression arrays", JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, SPRINGER INTERNATIONAL, BERLIN, DE, (20030515), vol. 129, no. 5, ISSN 0171-5216, pages 263 - 271, XP009088733 [A] * the whole document *
 [A]  - KWON HYUK-CHAN ET AL, "Gene expression profiling in lymph node-positive and lymph node-negative colorectal cancer", DISEASES OF THE COLON AND RECTUM, J.B. LIPPINCOT CO., PHILADELPHIA, US, (200402), vol. 47, no. 2, ISSN 0012-3706, pages 141 - 152, XP009088734 [A] * the whole document *

DOI:   http://dx.doi.org/10.1007/s10350-003-0032-7
 [A]  - KOEHLER ASTRID ET AL, "Gene expression profiling of colorectal cancer and metastases divides tumours according to their clinicopathological stage", JOURNAL OF PATHOLOGY, CHICHESTER, SUSSEX, GB, (200409), vol. 204, no. 1, ISSN 0022-3417, pages 65 - 74, XP009088735 [A] * the whole document *

DOI:   http://dx.doi.org/10.1002/path.1606
Examination   - KOMURO K ET AL, "Right- and left-sided colorectal cancers display distinct expression profiles and the anatomical stratification allows a high accuracy prediction of lymph node metastasis", JOURNAL OF SURGICAL RESEARCH, ACADEMIC PRESS INC., SAN DIEGO, CA, US LNKD- DOI:10.1016/J.JSS.2004.10.009, (20050401), vol. 124, no. 2, ISSN 0022-4804, pages 216 - 224, XP004835905

DOI:   http://dx.doi.org/10.1016/j.jss.2004.10.009
    - LI M ET AL, "GENES ASSOCIATED WITH LIVER METASTASIS OF COLON CANCER, IDENTIFIED BY GENOME-WIDE CDNA MICROARRAY", INTERNATIONAL JOURNAL OF ONCOLOGY, SPANDIDOS PUBLICATIONS, GR, (20040201), vol. 24, no. 2, ISSN 1019-6439, pages 305 - 312, XP009027443
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.