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Extract from the Register of European Patents

EP About this file: EP1984013

EP1984013 - MODIFICATIONS OF CST-II FOR INCREASED PROTEIN EXPRESSION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  30.11.2012
Database last updated on 26.07.2024
Most recent event   Tooltip18.07.2014Lapse of the patent in a contracting state
New state(s): HU		published on 20.08.2014  [2014/34]
Applicant(s)For all designated states
BioGeneriX AG
Janderstrasse 3
68199 Mannheim / DE
[2011/24]
Former [2009/29]For all designated states
Novo Nordisk A/S
Novo Allé
2880 Bagsværd / DK
Former [2008/44]For all designated states
Neose Technologies, Inc.
102 Rock Road
Horsham, PA 19044 / US
Inventor(s)01 / JOHNSON, Karl, F.
5230 Ivystream Road
Hatboro, Pennsylvania 19040 / US
02 / MOBASSERI, Aliakbar
29 Rollingwood Drive
Voorhees, New Jersey 08043 / US
03 / BAI, Xiaomei
12557-C El Camino Real
San Diego, California 92130 / US
04 / KINEALY, Kyle
192 Eaton Square
Plymouth Meeting, Pennsylvania 19462 / US
 [2008/44]
Representative(s)Engelhard, Markus, et al
Boehmert & Boehmert
Anwaltspartnerschaft mbB
Pettenkoferstrasse 22
80336 München / DE
[N/P]
Former [2010/52]Engelhard, Markus, et al
Forrester & Boehmert Pettenkoferstrasse 20-22
80336 München / DE
Former [2010/50]Engelhard, Markus
Forrester & Boehmert Pettenkoferstrasse 20-22
80336 München / DE
Former [2009/29]Atkinson, Jennifer
Barker Brettell LLP 138 Hagley Road Edgbaston Birmingham
B16 9PW / GB
Former [2008/44]Cripps, Joanna Elizabeth, et al
Mewburn Ellis LLP York House 23 Kingsway
London WC2B 6HP / GB
Application number, filing date07762625.701.02.2007
[2008/44]
WO2007US02878
Priority number, dateUS20060764499P01.02.2006         Original published format: US 764499 P
US20060764625P01.02.2006         Original published format: US 764625 P
US20060774088P15.02.2006         Original published format: US 774088 P
US20060773941P15.02.2006         Original published format: US 773941 P
[2008/44]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007089923
Date:09.08.2007
Language:EN
[2007/32]
Type: A2 Application without search report 
No.:EP1984013
Date:29.10.2008
Language:EN
The application published by WIPO in one of the EPO official languages on 09.08.2007 takes the place of the publication of the European patent application.
[2008/44]
Type: B1 Patent specification 
No.:EP1984013
Date:25.01.2012
Language:EN
[2012/04]
Search report(s)International search report - published on:US09.10.2008
(Supplementary) European search report - dispatched on:EP30.12.2009
ClassificationIPC:C12P21/02
[2009/14]
CPC:
C12N9/1081 (EP,US); C07K14/505 (EP,US)
Former IPC [2008/44]A61K38/16
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2008/44]
TitleGerman:CST-II-MODIFZIERUNGEN FÜR ERHÖHTE PROTEINEXPRESSION[2008/44]
English:MODIFICATIONS OF CST-II FOR INCREASED PROTEIN EXPRESSION[2008/44]
French:MODIFICATIONS DE CST-2 POUR UNE EXPRESSION PROTEINIQUE ACCRUE[2008/44]
Entry into regional phase20.08.2008National basic fee paid 
20.08.2008Search fee paid 
20.08.2008Designation fee(s) paid 
20.08.2008Examination fee paid 
Examination procedure20.08.2008Examination requested  [2008/44]
23.04.2010Despatch of a communication from the examining division (Time limit: M06)
02.11.2010Reply to a communication from the examining division
11.01.2011Despatch of a communication from the examining division (Time limit: M04)
05.05.2011Reply to a communication from the examining division
08.08.2011Communication of intention to grant the patent
05.12.2011Fee for grant paid
05.12.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.04.2010
Opposition(s)26.10.2012No opposition filed within time limit [2013/01]
Fees paidRenewal fee
26.02.2009Renewal fee patent year 03
16.02.2010Renewal fee patent year 04
22.02.2011Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU01.02.2007
AT25.01.2012
BE25.01.2012
CY25.01.2012
CZ25.01.2012
DK25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
RO25.01.2012
SE25.01.2012
SI25.01.2012
SK25.01.2012
TR25.01.2012
IE01.02.2012
LU01.02.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
[2014/34]
Former [2014/27]AT25.01.2012
BE25.01.2012
CY25.01.2012
CZ25.01.2012
DK25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
RO25.01.2012
SE25.01.2012
SI25.01.2012
SK25.01.2012
TR25.01.2012
IE01.02.2012
LU01.02.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2014/21]AT25.01.2012
BE25.01.2012
CY25.01.2012
CZ25.01.2012
DK25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
RO25.01.2012
SE25.01.2012
SI25.01.2012
SK25.01.2012
TR25.01.2012
IE01.02.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2013/08]AT25.01.2012
BE25.01.2012
CY25.01.2012
CZ25.01.2012
DK25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
RO25.01.2012
SE25.01.2012
SI25.01.2012
SK25.01.2012
IE01.02.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2013/07]AT25.01.2012
BE25.01.2012
CY25.01.2012
CZ25.01.2012
DK25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
RO25.01.2012
SE25.01.2012
SI25.01.2012
SK25.01.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/50]BE25.01.2012
CY25.01.2012
CZ25.01.2012
DK25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
RO25.01.2012
SE25.01.2012
SI25.01.2012
SK25.01.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/49]BE25.01.2012
CY25.01.2012
CZ25.01.2012
DK25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
RO25.01.2012
SE25.01.2012
SI25.01.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/48]BE25.01.2012
CY25.01.2012
EE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
SE25.01.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/42]BE25.01.2012
CY25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
MC29.02.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/41]BE25.01.2012
CY25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/39]BE25.01.2012
FI25.01.2012
LT25.01.2012
LV25.01.2012
PL25.01.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/37]BE25.01.2012
FI25.01.2012
LT25.01.2012
PL25.01.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
PT25.05.2012
Former [2012/36]BE25.01.2012
LT25.01.2012
BG25.04.2012
GR26.04.2012
IS25.05.2012
Former [2012/35]BE25.01.2012
LT25.01.2012
BG25.04.2012
IS25.05.2012
Former [2012/34]BE25.01.2012
LT25.01.2012
IS25.05.2012
Former [2012/33]BE25.01.2012
LT25.01.2012
Documents cited:Search[A]US2004152165  (GILBERT MICHEL [CA], et al) [A] 1-19 * paragraphs [0072] - [0074]; claims 11,12 *;
 [X]  - CHIU C P ET AL, "Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog", NATURE STRUCTURAL AND MOLECULAR BIOLOGY, NATURE PUBLISHING GROUP, US, vol. 11, no. 2, ISSN 1545-9993, (20040201), pages 163 - 170, (20040118), XP008099169 [X] 1-19 * page 168, column 2, paragraph 3 * * page 169, column 1, paragraph 3 *

DOI:   http://dx.doi.org/10.1038/nsmb720
 [A]  - KAZUYA I P J HIDARI ET AL, "Purification and characterization of a soluble recombinant human ST6Gal I functionally expressed in Escherichia coli", GLYCOCONJUGATE JOURNAL, KLUWER ACADEMIC PUBLISHERS, BO, (20050201), vol. 22, no. 1-2, ISSN 1573-4986, pages 1 - 11, XP019207047 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1007/s10719-005-0845-9
 [A]  - KIM HYUNG GU ET AL, "High-level expression of human glycosyltransferases in insect cells as biochemically active form.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 6 JUN 2003, (20030606), vol. 305, no. 3, ISSN 0006-291X, pages 488 - 493, XP002559401 [A] 1-19 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0006-291X(03)00795-2
International search[X]US6699705  (GILBERT MICHEL [CA], et al);
 [Y]WO2005051327  (NEOSE TECHNOLOGIES INC [US], et al);
 [Y]  - HIREI ET AL., "Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain lenght of the penultimate amino acid", PROC. NATL. ACAD. SCI. (USA), (198911), vol. 86, no. 21, pages 8247 - 8251, XP002995219

DOI:   http://dx.doi.org/10.1073/pnas.86.21.8247
 [Y]  - "pMAL Protein Fusion and Purification System", NEW ENGLAND BIOLABS DATASHEET, (20040910), URL: http://www.web.archive.org/web/20040910192107/http://www.neb.com/nebecomm/products_intl/productE8000.asp, XP008131722
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.