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Extract from the Register of European Patents

EP About this file: EP2049143

EP2049143 - IMPROVED ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  10.01.2014
Database last updated on 24.08.2024
Most recent event   Tooltip10.01.2014Application deemed to be withdrawnpublished on 12.02.2014  [2014/07]
Applicant(s)For all designated states
AVI BioPharma, Inc.
Suite 200, 4575 S.W. Research Way
Corvallis, OR 97333 / US
[2009/17]
Inventor(s)01 / WELLER, Dwight, D.
3323 N.W. Elmwood Drive
Corvallis, OR 97330 / US
02 / GELLER, Bruce, L.
6994 N.W. Concord Drive
Corvallis, OR 97330 / US
03 / IVERSEN, Patrick, L.
5902 N.W. Fair Oaks Place
Corvallis, OR 97333 / US
04 / TILLEY, Lucas, D.
36 Little Eagle Boy
Burlington, VT 05408 / US
05 / HASSINGER, Jed, N.
24319 Price Creek Road
Philomath, OR 97370 / US
 [2009/23]
Former [2009/17]01 / WELLER, Dwight, D.
3323 N.W. Elmwood Drive
Corvallis, OR 97330 / US
02 / GELLER, Bruce, L.
6994 N.W. Concord Drive
Corvallis, OR 97330 / US
03 / IVERSEN, Patrick, L.
5902 N.W. Fair Oaks Place
Corvallis, OR 97333 / US
04 / TILLEY, Lucas, D.
36 Little Eagle Bay
Burlingame, VT 05408 / US
05 / HASSINGER, Jed, N.
24319 Price Creek Road
Philomath, OR 97370 / US
Representative(s)Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB
Ganghoferstraße 68 B
80339 München / DE
[N/P]
Former [2011/42]Schiweck, Weinzierl & Koch
European Patent Attorneys Landsberger Straße 98
80339 München / DE
Former [2009/17]Barth, Renate, et al
Vossius & Partner Siebertstrasse 4
81675 München / DE
Application number, filing date07794801.611.05.2007
[2009/17]
WO2007US11431
Priority number, dateUS2006048700913.07.2006         Original published format: US 487009
[2009/17]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008008113
Date:17.01.2008
Language:EN
[2008/03]
Type: A1 Application with search report 
No.:EP2049143
Date:22.04.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 17.01.2008 takes the place of the publication of the European patent application.
[2009/17]
Search report(s)International search report - published on:US17.01.2008
(Supplementary) European search report - dispatched on:EP18.10.2010
ClassificationIPC:C12N15/11, A61K38/16, A61K31/70, A61K31/675
[2010/46]
CPC:
A61K48/00 (EP,US); A61P31/04 (EP); C12N15/111 (EP,US);
C12N15/113 (EP,US); C12N2310/11 (EP,US); C12N2310/3233 (EP,US);
C12N2310/3513 (EP,US); C12N2320/50 (EP,US) (-)
Former IPC [2009/17]A61K38/16, A61K31/70, A61K31/675
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/17]
TitleGerman:VERBESSERTES ANTIBAKTERIELLES ANTISENSE-OLIGONUKLEOTID UND VERFAHREN[2009/17]
English:IMPROVED ANTIBACTERIAL ANTISENSE OLIGONUCLEOTIDE AND METHOD[2009/17]
French:OLIGONUCLÉOTIDE ANTISENS ANTIBACTÉRIEN AMÉLIORÉ ET PROCÉDÉ[2009/17]
Entry into regional phase13.02.2009National basic fee paid 
13.02.2009Search fee paid 
13.02.2009Designation fee(s) paid 
13.02.2009Examination fee paid 
Examination procedure13.02.2009Examination requested  [2009/17]
13.05.2011Amendment by applicant (claims and/or description)
21.06.2011Despatch of a communication from the examining division (Time limit: M06)
02.01.2012Reply to a communication from the examining division
13.03.2012Despatch of a communication from the examining division (Time limit: M06)
21.09.2012Reply to a communication from the examining division
12.02.2013Despatch of a communication from the examining division (Time limit: M06)
23.08.2013Application deemed to be withdrawn, date of legal effect  [2014/07]
24.09.2013Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2014/07]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.06.2011
Fees paidRenewal fee
13.02.2009Renewal fee patent year 03
25.05.2010Renewal fee patent year 04
25.05.2011Renewal fee patent year 05
25.05.2012Renewal fee patent year 06
28.05.2013Renewal fee patent year 07
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Documents cited:Search[A]WO2004097017  (AVI BIOPHARMA INC [US], et al) [A] 1-15 * the whole document *;
 [A]WO2006050414  (AVI BIOPHARMA INC [US], et al) [A] 1-15 * example 3 *;
 [XP]WO2007009094  (AVI BIOPHARMA INC [US], et al) [XP] 1-15 * the whole document *;
 [A]  - GELLER B L ET AL, "Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC, US LNKD- DOI:10.1128/AAC.47.10.3233-3239.2003, (20031001), vol. 47, no. 10, ISSN 0066-4804, pages 3233 - 3239, XP002402831 [A] 1-15 * table 2 *

DOI:   http://dx.doi.org/10.1128/AAC.47.10.3233-3239.2003
 [A]  - DEERE JESSE ET AL, "Antisense phosphorodiamidate morpholino oligomer length and target position effects on gene-specific inhibition in Escherichia coli", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC, US LNKD- DOI:10.1128/AAC.49.1.249-255.2005, (20050101), vol. 49, no. 1, ISSN 0066-4804, pages 249 - 255, XP002402833 [A] 1-15 * table 1 *

DOI:   http://dx.doi.org/10.1128/AAC.49.1.249-255.2005
 [A]  - GELLER B L ET AL, "Antisense Phosphorodiamidate Morpholino Oligomer Inhibits Viability of Escherichia coli in Pure Culture and in Mouse Peritonitis", JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, OXFORD UNIVERSITY PRESS, GB LNKD- DOI:10.1093/JAC/DKI129, (20050504), vol. 55, ISSN 0305-7453, pages 983 - 988, XP003008448 [A] 1-15 * page 984, column l; figure 1 *

DOI:   http://dx.doi.org/10.1093/jac/dki129
 [A]  - NELSON MICHELLE H ET AL, "Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity", BIOCONJUGATE CHEMISTRY, ACS, WASHINGTON, DC, US LNKD- DOI:10.1021/BC0501045, (20050701), vol. 16, no. 4, ISSN 1043-1802, pages 959 - 966, XP002543913 [A] 1-15 * table 1 *

DOI:   http://dx.doi.org/10.1021/bc0501045
 [A]  - MOULTON H M ET AL, "CELLULAR UPTAKE OF ANTISENSE MORPHOLINO OLIGOMERS CONJUGATED TO ARGININE-RICH PEPTIDES", BIOCONJUGATE CHEMISTRY, ACS, WASHINGTON, DC, US LNKD- DOI:10.1021/BC034221G, (20040101), vol. 15, no. 2, ISSN 1043-1802, pages 290 - 299, XP002999956 [A] 1-15 * page 291, column l; table 1 *

DOI:   http://dx.doi.org/10.1021/bc034221g
 [XP]  - TILLEY L D ET AL, "Gene-Specific Effects of Antisense Phosphorodiamidate Morpholino Oligomer-peptide Conjugates on Eschericia coli and Salmonella enterica Serovar Typhimurium in Pure Culture and in Tissue Culture", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC, US LNKD- DOI:10.1128/AAC.01286-05, (20060801), vol. 50, no. 8, ISSN 0066-4804, pages 2789 - 2796, XP003008447 [XP] 1-15 * figures 4-6 *

DOI:   http://dx.doi.org/10.1128/AAC.01286-05
International search[X]US2006148747  (STEIN DAVID A [US], et al);
 [Y]US7049431  (IVERSEN PATRICK L [US]);
 [A]US6548651  (NIELSEN PETER E [DK], et al)
Examination   - Derek S. Youngblood ET AL, "Stability of Cell-Penetrating Peptide-Morpholino Oligomer Conjugates in Human Serum and in Cells", Bioconjugate Chemistry, (20070101), vol. 18, no. 1, doi:10.1021/bc060138s, ISSN 1043-1802, pages 50 - 60, XP055031622

DOI:   http://dx.doi.org/10.1021/bc060138s
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.