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Extract from the Register of European Patents

EP About this file: EP2023938

EP2023938 - MODULATION OF CHREBP EXPRESSION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  03.08.2012
Database last updated on 28.05.2024
Most recent event   Tooltip03.08.2012Application deemed to be withdrawnpublished on 05.09.2012  [2012/36]
Applicant(s)For all designated states
Isis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
[2011/39]
Former [2009/08]For all designated states
Isis Pharmaceuticals, Inc.
1896 Rutherford Road
Carlsbad, CA 92008 / US
Inventor(s)01 / BHANOT, Sanjay
8094 Paseo Arrayan
Carlsbad, CA 92009 / US
02 / DOBIE, Kenneth, W.
703 Stratford Ct 4
Del Mar, CA 92014 / US
03 / MURRAY, Susan, F.
13248 Ann-O-Reno Lane
Ponway, CA 92064 / US
 [2009/20]
Former [2009/08]01 / BHANOT, Sanjay
8094 Paseo Arrayan
Carlsbad, CA 92009 / US
02 / DOBIE, Kenneth, W.
703 Stratford Ct 4
Del Mar, CA 92014 / US
03 / MURRAY, Susan, F.
3648 Jetty Point
Carlsbad, CA 92010 / US
Representative(s)Hallybone, Huw George, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2009/08]Hallybone, Huw George, et al
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date07797701.523.05.2007
[2009/08]
WO2007US69587
Priority number, dateUS20060802948P23.05.2006         Original published format: US 802948 P
[2009/08]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2007137301
Date:29.11.2007
Language:EN
[2007/48]
Type: A2 Application without search report 
No.:EP2023938
Date:18.02.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 29.11.2007 takes the place of the publication of the European patent application.
[2009/08]
Search report(s)International search report - published on:US06.03.2008
(Supplementary) European search report - dispatched on:EP13.10.2010
ClassificationIPC:A61K31/70, C07H21/02, C07H21/04, C12N5/00, C12Q1/68
[2009/08]
CPC:
C12N15/113 (EP,US); A61P3/04 (EP); A61P3/10 (EP);
C12N2310/11 (EP,US); C12N2310/322 (EP,US); C12N2310/341 (EP,US)
C-Set:
C12N2310/322, C12N2310/3525 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/08]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:MODULATION VON CHREBP-EXPRESSION[2009/08]
English:MODULATION OF CHREBP EXPRESSION[2009/08]
French:MODULATION DE L'EXPRESSION DE ChREBP[2009/08]
Entry into regional phase19.12.2008National basic fee paid 
19.12.2008Search fee paid 
19.12.2008Designation fee(s) paid 
19.12.2008Examination fee paid 
Examination procedure19.12.2008Examination requested  [2009/08]
11.05.2011Amendment by applicant (claims and/or description)
14.10.2011Despatch of a communication from the examining division (Time limit: M04)
25.02.2012Application deemed to be withdrawn, date of legal effect  [2012/36]
04.04.2012Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2012/36]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.10.2011
Fees paidRenewal fee
19.12.2008Renewal fee patent year 03
31.03.2010Renewal fee patent year 04
10.05.2011Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.05.201206   M06   Not yet paid
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Documents cited:Search[A]US2003124590  (UYEDA KOSAKU [US]) [A] 1-15* the whole document *
International search[Y]  - BHANOT ET AL., "Carbohydrate Responsive Element-Binding protein Antisense Oligonucleotides Decrease Hepatic ChREBP Expression and Lower Hyperglycemia in ob/ob mice", DIABETES, (2005), vol. 54, no. SUPPL. 1, page A376, XP008101353
 [AT]  - ZHANG ET AL., "Aberrant Hepatic Expression of PPAR.gamma.2 Stimulates Hepatic. Lipogenesis in a Mouse Model of Obesity, Insulin Resistance, Dyslipidemia, and Hepatic Steatosis", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (20061208), vol. 281, no. 49, pages 37603 - 37615, XP008101632

DOI:   http://dx.doi.org/10.1074/JBC.M604709200
Examination   - K. Iizuka, "From The Cover: Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis", Proceedings of the National Academy of Sciences, (20040101), vol. 101, no. 19, doi:10.1073/pnas.0401516101, ISSN 0027-8424, pages 7281 - 7286, XP055009117

DOI:   http://dx.doi.org/10.1073/pnas.0401516101
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.