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Extract from the Register of European Patents

EP About this file: EP2190859

EP2190859 - GENES AND PROTEINS FOR THE BIOSYNTHESIS OF THE LANTIBIOTIC 107891 [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.03.2015
Database last updated on 12.07.2024
Most recent event   Tooltip06.03.2015Application deemed to be withdrawnpublished on 08.04.2015  [2015/15]
Applicant(s)For all designated states
Sentinella Pharmaceuticals, Inc. ("Sentinella")
47 Hulfish Street, Suite 310
Princeton NJ 08542 / US
[2010/22]
Inventor(s)01 / DONADIO, Stefano
Via Cav. Brusa, 43
I-21046 Malnate (VA) / IT
02 / SOSIO, Margherita
Via Monte Grappa, 5
I-20020 Solaro (MI) / IT
03 / SERINA, Stefania
Via Lanfranco della Pila, 5
I-20126 Milano / IT
04 / MERCORILLO, Davide
Via Libertà, 40
I-20020 Lazzate (MI) / IT
 [2010/22]
Representative(s)Trupiano, Federica
Marietti, Gislon e Trupiano S.r.l.
Via Larga, 16
20122 Milano / IT
[N/P]
Former [2010/22]Trupiano, Federica
Marietti, Gislon e Trupiano S.r.l. Via Larga, 16
I-20122 Milano / IT
Application number, filing date07804726.303.08.2007
[2010/22]
WO2007IB02270
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009019524
Date:12.02.2009
Language:EN
[2009/07]
Type: A1 Application with search report 
No.:EP2190859
Date:02.06.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 12.02.2009 takes the place of the publication of the European patent application.
[2010/22]
Search report(s)International search report - published on:EP12.02.2009
ClassificationIPC:C07K7/04, C12N15/76
[2010/22]
CPC:
C07K14/37 (EP,US); C07K14/195 (US); A61P31/04 (EP);
C12N15/52 (EP,US); C12N15/74 (US); C12N15/746 (US);
C12N15/75 (US); C12N15/76 (US); C12N9/0004 (EP,US);
C12N9/0077 (EP,US); C12N9/14 (EP,US); C12N9/88 (EP,US);
C12P21/02 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/22]
TitleGerman:GENE UND PROTEINE FÜR DIE BIOSYNTHESE DES LANTIBIOTIKUMS 107891[2010/22]
English:GENES AND PROTEINS FOR THE BIOSYNTHESIS OF THE LANTIBIOTIC 107891[2010/22]
French:GÈNES ET PROTÉINES POUR LA BIOSYNTHÈSE DE LANTIBIOTIQUE 107891[2010/22]
Entry into regional phase01.03.2010National basic fee paid 
01.03.2010Designation fee(s) paid 
01.03.2010Examination fee paid 
Examination procedure28.05.2009Request for preliminary examination filed
International Preliminary Examining Authority: EP
01.03.2010Examination requested  [2010/22]
23.07.2010Despatch of a communication from the examining division (Time limit: M04)
26.11.2010Reply to a communication from the examining division
17.06.2011Despatch of a communication from the examining division (Time limit: M06)
15.12.2011Reply to a communication from the examining division
02.07.2012Despatch of a communication from the examining division (Time limit: M04)
07.11.2012Reply to a communication from the examining division
27.03.2013Despatch of a communication from the examining division (Time limit: M04)
13.06.2013Reply to a communication from the examining division
26.09.2013Despatch of a communication from the examining division (Time limit: M04)
27.01.2014Reply to a communication from the examining division
01.04.2014Despatch of a communication from the examining division (Time limit: M02)
19.05.2014Reply to a communication from the examining division
13.06.2014Despatch of a communication from the examining division (Time limit: M04)
24.10.2014Application deemed to be withdrawn, date of legal effect  [2015/15]
19.11.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/15]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.07.2010
Fees paidRenewal fee
01.03.2010Renewal fee patent year 03
10.08.2010Renewal fee patent year 04
05.08.2011Renewal fee patent year 05
27.08.2012Renewal fee patent year 06
09.08.2013Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
31.08.201408   M06   Not yet paid
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Cited inInternational search[Y]WO03076898  (UNIV MINNESOTA [US], et al) [Y] 1-3,5-7,10-31,33 * claim -; sequence 411 *;
 [A]US2004101963  (BIBB MERVYN JAMES [US], et al) [A] 1-3,5-7,10-31,33;
 [Y]WO2005014628  (VICURON PHARM INC [US], et al) [Y] 1-3,5-7,10-31,33 * claim - *;
 [A]JP2006514551  (UNIV UNIV MINNESOTA) [A] 1,2,7,11-31,33* the whole document *;
 [Y]  - SIEZEN R J ET AL, "COMPARISON OF LANTIBIOTIC GENE CLUSTERS AND ENCODED PROTEINS", ANTONIE VAN LEEUWENHOEK, DORDRECHT, NL, (199602), vol. 2, no. 69, pages 171 - 184, XP001095134 [Y] 1,10,12-24,28,33 * the whole document *

DOI:   http://dx.doi.org/10.1007/BF00399422
 [Y]  - WIDDICK D A ET AL, "Cloning and engineering of the cinnamycin biosynthetic gene cluster from Streptomyces cinnamoneus cinnamoneus DSM 40005", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, (20030401), vol. 100, no. 7, ISSN 0027-8424, pages 4316 - 4321, XP002394064 [Y] 1,10,12-24,28,33 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.0230516100
 [A]  - MCAULIFFE OLIVIA ET AL, "Lantibiotics: Structure, biosynthesis and mode of action", FEMS MICROBIOLOGY REVIEWS, ELSEVIER, AMSTERDAM, NL, (200105), vol. 25, no. 3, ISSN 0168-6445, pages 285 - 308, XP002209342 [A] * the whole document *

DOI:   http://dx.doi.org/10.1016/S0168-6445(00)00065-6
 [A]  - HILLMAN J D ET AL, "Genetic and biochemical analysis of mutacin 1140, a lantibiotic and Streptococcus mutans", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, (199806), vol. 66, no. 6, ISSN 0019-9567, pages 2743 - 2749, XP002394065 [A] * the whole document *
 [A]  - GILLOR O ET AL, "GENETICALLY ENGINEERED BACTERIOCINS AND THEIR POTENTIAL AS THE NEXT GENERATION OF ANTIMICROBIALS", CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBLISHERS, SCHIPHOL, NL, (200503), vol. 11, no. 8, ISSN 1381-6128, pages 1067 - 1075, XP009070550 [A] * the whole document *

DOI:   http://dx.doi.org/10.2174/1381612053381666
 [A]  - VOLOKHAN O ET AL, "An unexpected role for the putative 4'-phosphopantetheinyl transferase-encoding gene nysF in the regulation of nystatin biosynthesis in Streptomyces noursei ATCC 11455", FEMS MICROBIOLOGY LETTERS, AMSTERDAM, NL, (20050801), vol. 249, no. 1, ISSN 0378-1097, pages 57 - 64, XP004981910 [A] 1-3,5-7,10-31,33 * Abstract *

DOI:   http://dx.doi.org/10.1016/j.femsle.2005.05.052
 [Y]  - KLEIN C ET AL, "ANALYSIS OF GENES INVOLVED IN BIOSYNTHESIS OF THE LANTIBIOTIC SUBTILIN", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (1992), vol. 58, no. 1, ISSN 0099-2240, pages 132 - 142, XP002477136 [Y] 1-3,5-7,10-31,33 * the whole document *
 [A]  - RENDULIC SNJEZANA ET AL, "A predator unmasked: Life cycle of Bdellovibrio bacteriovorus from a genomic perspective.", SCIENCE (WASHINGTON D C), (20040130), vol. 303, no. 5658, ISSN 0036-8075, pages 689 - 692, XP002477137 [A] 1-3,5-7,10-31,33 * the whole document *

DOI:   http://dx.doi.org/10.1126/science.1093027
by applicantUS2004101963
 WO2005014628
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