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Extract from the Register of European Patents

EP About this file: EP2094850

EP2094850 - CANCER-RELATED PROTEIN KINASES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.04.2014
Database last updated on 11.04.2026
Most recent event   Tooltip04.09.2015Lapse of the patent in a contracting state
New state(s): MT		published on 07.10.2015  [2015/41]
Applicant(s)For all designated states
Agency for Science, Technology And Research
1 Fusionopolis Way 20-10 Connexis
Singapore 138632 / SG
[2009/36]
Inventor(s)01 / ULLRICH, Axel
Brunnstr. 5
80331 Munich / DE
02 / RUHE, Jens
21 Telok Blangah Drive 19-06
Singapore 109258 / SG
03 / HART, Stefan
127 Sunset Way, no. 06-03
Singapore 597156 / SG
04 / STREIT, Sylvia
21 Telok Blangah Drive 19-06
Singapore 109258 / SG
05 / WONG, Chee Hong
Block 52 Strathmore Avenue 38-237
Singapore 141052 / SG
06 / CHUA, Boon Tin
Block 151 Yung Ho Road 10-85
Singapore 610151 / SG
07 / HO, Han Kiat
44 Choa Chu Kang Street 64, 17-19
Singapore 689105 / SG
 [2010/44]
Former [2009/36]01 / ULLRICH, Axel
Brunnstr. 5
80331 Munich / DE
02 / RUHE, Jens
21 Telok Blangah Drive 19-06
Singapore 109258 / SG
03 / HART, Stefan
135 Sunset Way 06-15
Singapore 597152 / SG
04 / STREIT, Sylvia
21 Telok Blangah Drive 19-06
Singapore 109258 / SG
05 / WONG, Chee Hong
Block 52 Strathmore Avenue 38-237
Singapore 141052 / SG
06 / CHUA, Boon Tin
Block 151 Yung Ho Road 10-85
Singapore 610151 / SG
07 / HO, Han Kiat
44 Choa Chu Kang Street 64, 17-19
Singapore 689105 / SG
Representative(s)Viering, Jentschura & Partner mbB Patent- und Rechtsanwälte
Hamborner Straße 53
40472 Düsseldorf / DE
[N/P]
Former [2012/33]Viering, Jentschura & Partner
Kennedydamm 55 / Roßstrasse
40476 Düsseldorf / DE
Former [2011/21]Häusler, Lars Christian
Viering, Jentschura & Partner Kenneydamm 55 / Roßstraße
40476 Düsseldorf / DE
Former [2009/36]Viering, Jentschura & Partner
Grillparzerstrasse 14
81675 München / DE
Application number, filing date07852282.803.12.2007
[2009/36]
WO2007SG00412
Priority number, dateUS20060868173P01.12.2006         Original published format: US 868173 P
[2009/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008066498
Date:05.06.2008
Language:EN
[2008/23]
Type: A1 Application with search report 
No.:EP2094850
Date:02.09.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 05.06.2008 takes the place of the publication of the European patent application.
[2009/36]
Type: B1 Patent specification 
No.:EP2094850
Date:12.06.2013
Language:EN
[2013/24]
Search report(s)International search report - published on:AU05.06.2008
(Supplementary) European search report - dispatched on:EP01.07.2010
ClassificationIPC:G01N33/574, C12N9/12
[2012/15]
CPC:
G01N33/57557 (EP,US); A61P35/00 (EP); A61P43/00 (EP);
C12N9/1205 (EP,US); G01N33/57525 (EP,US)
Former IPC [2010/21]C12N15/52, C07K16/00, C07K16/40, C07K14/47, C07K16/28, C12N9/00, C07K14/71, C07K16/30, C12N15/12, G01N33/574
Former IPC [2009/36]C12N15/52, C07K16/00, C07K16/40, C07K14/47, C07K16/28, C12N9/00, C07K14/71, C07K16/30, C12N15/12
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/36]
TitleGerman:PROTEINKINASEN IN VERBINDUNG MIT KREBS[2009/36]
English:CANCER-RELATED PROTEIN KINASES[2009/36]
French:PROTÉINE KINASES LIÉES AU CANCER[2009/36]
Entry into regional phase29.06.2009National basic fee paid 
29.06.2009Search fee paid 
29.06.2009Designation fee(s) paid 
29.06.2009Examination fee paid 
Examination procedure30.09.2008Request for preliminary examination filed
International Preliminary Examining Authority: AU
29.06.2009Examination requested  [2009/36]
19.01.2011Amendment by applicant (claims and/or description)
18.03.2011Despatch of a communication from the examining division (Time limit: M02)
24.05.2011Reply to a communication from the examining division
10.10.2011Despatch of a communication from the examining division (Time limit: M04)
10.02.2012Reply to a communication from the examining division
02.05.2012Communication of intention to grant the patent
30.08.2012Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
30.08.2012Fee for grant paid
30.08.2012Fee for publishing/printing paid
04.12.2012Communication of intention to grant the patent
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.03.2011
Opposition(s)13.03.2014No opposition filed within time limit [2014/21]
Fees paidRenewal fee
31.12.2009Renewal fee patent year 03
31.12.2010Renewal fee patent year 04
02.01.2012Renewal fee patent year 05
30.04.2013Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.12.201206   M06   Fee paid on   30.04.2013
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT12.06.2013
BE12.06.2013
CY12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
MT12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
TR12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
GB03.12.2013
IE03.12.2013
LU03.12.2013
HU04.12.2013
CH31.12.2013
FR31.12.2013
LI31.12.2013
[2015/41]
Former [2015/32]AT12.06.2013
BE12.06.2013
CY12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
TR12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
GB03.12.2013
IE03.12.2013
LU03.12.2013
HU04.12.2013
CH31.12.2013
FR31.12.2013
LI31.12.2013
Former [2015/30]AT12.06.2013
BE12.06.2013
CY12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
GB03.12.2013
IE03.12.2013
LU03.12.2013
HU04.12.2013
CH31.12.2013
FR31.12.2013
LI31.12.2013
Former [2014/51]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
GB03.12.2013
IE03.12.2013
LU03.12.2013
HU04.12.2013
CH31.12.2013
FR31.12.2013
LI31.12.2013
Former [2014/50]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
GB03.12.2013
IE03.12.2013
LU03.12.2013
HU04.12.2013
CH31.12.2013
LI31.12.2013
Former [2014/48]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
IE03.12.2013
LU03.12.2013
CH31.12.2013
LI31.12.2013
Former [2014/46]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
LU03.12.2013
CH31.12.2013
LI31.12.2013
Former [2014/38]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
MC12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
LU03.12.2013
Former [2014/24]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
IT12.06.2013
LT12.06.2013
LV12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/21]AT12.06.2013
BE12.06.2013
CZ12.06.2013
DK12.06.2013
EE12.06.2013
FI12.06.2013
LT12.06.2013
LV12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/14]AT12.06.2013
BE12.06.2013
CZ12.06.2013
EE12.06.2013
FI12.06.2013
LT12.06.2013
LV12.06.2013
NL12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/11]AT12.06.2013
BE12.06.2013
CZ12.06.2013
EE12.06.2013
FI12.06.2013
LT12.06.2013
LV12.06.2013
PL12.06.2013
RO12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/10]AT12.06.2013
BE12.06.2013
CZ12.06.2013
EE12.06.2013
FI12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
SK12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
IS12.10.2013
PT14.10.2013
Former [2014/09]AT12.06.2013
BE12.06.2013
EE12.06.2013
FI12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
PT14.10.2013
Former [2014/08]BE12.06.2013
FI12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
PT14.10.2013
Former [2014/02]FI12.06.2013
LT12.06.2013
LV12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
Former [2013/50]FI12.06.2013
LT12.06.2013
SE12.06.2013
SI12.06.2013
BG12.09.2013
GR13.09.2013
ES23.09.2013
Former [2013/49]FI12.06.2013
LT12.06.2013
SE12.06.2013
SI12.06.2013
GR13.09.2013
ES23.09.2013
Former [2013/48]LT12.06.2013
ES23.09.2013
Former [2013/47]LT12.06.2013
Documents cited:Search[A]   STREIT SYLVIA ET AL: "Involvement of the FGFr4 Arg388 allele in head and neck squamous cell carcinoma", INTERNATIONAL JOURNAL OF CANCER, JOHN WILEY & SONS, INC, UNITED STATES, SWITZERLAND, GERMANY LNKD- DOI:10.1002/IJC.20204, vol. 111, no. 2, 20 August 2004 (2004-08-20), pages 213 - 217, XP002517570, ISSN: 0020-7136, [retrieved on 20040412] [A] 1,3-15 * the whole document * * In particular: Title; Abstract; Material and Methods section; Results, paragraphs 1-2. *

DOI:   http://dx.doi.org/10.1002/ijc.20204
 [A]   STREIT S ET AL: "FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients", BRITISH JOURNAL OF CANCER 20060619 GB LNKD- DOI:10.1038/SJ.BJC.6603181, vol. 94, no. 12, 19 June 2006 (2006-06-19), pages 1879 - 1886, XP002577219 [A] 1,3-15 * the whole document * * In particular: Title; Abstract; Materials and Methods section; Results, paragraphs 2 and 3. *

DOI:   http://dx.doi.org/10.1038/sj.bjc.6603181
 [A]   THUSSBAS CHRISTOPH ET AL: "FGFR4 ARG388 ALLELE IS ASSOCIATED WITH RESISTANCE TO ADJUVANT THERAPY IN PRIMARY BREAST CANCER", JOURNAL OF CLINICAL ONCOLOGY, AMERICAN SOCIETY OF CLINICAL ONCOLOGY, US LNKD- DOI:10.1200/JCO.2005.04.8587, vol. 24, no. 23, 10 August 2006 (2006-08-10), pages 3747 - 3755, XP008076988, ISSN: 0732-183X [A] 1,3-15 * the whole document * * In particular: Title; Abstract; Methods section. *

DOI:   http://dx.doi.org/10.1200/JCO.2005.04.8587
International search[X] WO2004074485  (RES ASS FOR BIOTECHNOLOGY et al.)
 [X] WO2005031001  (CHIRON CORP et al.)
 [X] US2006194265  (MORRIS DAVID W et al.)
 [X] WO0231198  (AVALON PHARMACEUTICALS et al.)
 [X] WO03065006  (MILLENNIUM PHARM INC et al.)
 [A] JP2005198640  (BIOMARKER SCIENCE KK et al.)
 [X]   EZZAT S. ET AL.: "Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis", JOURNAL OF CLINICAL INVESTIGATION, vol. 109, no. 1, 2002, pages 69 - 78, XP008109194
 [X]   RON D. ET AL.: "Fibroblast Growth Factor Receptor 4 Is a High Affinity Receptor for Both Acidic and Basic Fibroblast Growth Factor but Not for Keratinocyte Growth Factor", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 268, no. 8, 1993, pages 5388 - 5394, XP008109195
 [A]   KOSTRZEWA M. AND MOLLER U.: "Genomic structure and complete sequence of the human FGFR4 gene", MAMMALIAN GENOME, vol. 9, no. 2, 1998, pages 131 - 135, XP002441350

DOI:   http://dx.doi.org/10.1007/s003359900703
by applicantUS4376110
 WO0192655
 US2005191618
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.