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Extract from the Register of European Patents

EP About this file: EP2110384

EP2110384 - HEPATOPOIETIN AND USE THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.05.2017
Database last updated on 16.09.2024
Most recent event   Tooltip21.09.2018Lapse of the patent in a contracting state
New state(s): MT		published on 24.10.2018  [2018/43]
Applicant(s)For all designated states
Institute of Radiation Medicine, Academy of Military Medical Sciences Pla
27 Taiping Road
Beijing 100850 / CN
[2009/43]
Inventor(s)01 / WU, Zuze
No.27, Taiping Road
Beijing 100850 / CN
02 / SHI, Bingxing
No.27, Taiping Road
Beijing 100850 / CN
03 / CUI, Chunping
No.27, Taiping Road
Beijing 100850 / CN
04 / DU, Shaojun
No.27, Taiping Road
Beijing 100850 / CN
05 / WU, Danli
No.27, Taiping Road
Beijing 100850 / CN
 [2009/43]
Representative(s)Lavoix
2, place d'Estienne d'Orves
75441 Paris Cedex 09 / FR
[N/P]
Former [2016/27]Jacobson, Claude
Cabinet Lavoix
2, Place d'Estienne d'Orves
75441 Paris Cedex 09 / FR
Former [2009/43]Jacobson, Claude
Cabinet Lavoix 2, place d'Estienne d'Orves
75441 Paris Cedex 09 / FR
Application number, filing date07855737.821.12.2007
[2009/43]
WO2007CN03722
Priority number, dateCN20061015629826.12.2006         Original published format: CN200610156298
[2009/43]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008077311
Date:03.07.2008
Language:ZH
[2008/27]
Type: A1 Application with search report 
No.:EP2110384
Date:21.10.2009
Language:EN
[2009/43]
Type: B1 Patent specification 
No.:EP2110384
Date:06.07.2016
Language:EN
[2016/27]
Search report(s)International search report - published on:CN03.07.2008
(Supplementary) European search report - dispatched on:EP10.09.2010
ClassificationIPC:C07K14/475, C12N15/12, A61K38/18, A61K31/7088, A61K48/00, A61P1/16, A61P35/00
[2009/43]
CPC:
C07K14/4753 (EP,US); A61K31/7088 (EP,US); A61P1/16 (EP);
A61P35/00 (EP); A61K38/00 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/27]
Former [2009/43]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:HEPATOPOIETIN UND ANWENDUNG DAVON[2009/43]
English:HEPATOPOIETIN AND USE THEREOF[2009/43]
French:HEPATOPOIETINE ET SON UTILISATION[2009/43]
Entry into regional phase23.07.2009Translation filed 
23.07.2009National basic fee paid 
23.07.2009Search fee paid 
23.07.2009Designation fee(s) paid 
23.07.2009Examination fee paid 
Examination procedure28.07.2008Request for preliminary examination filed
International Preliminary Examining Authority: CN
23.07.2009Examination requested  [2009/43]
23.03.2011Amendment by applicant (claims and/or description)
03.11.2014Despatch of a communication from the examining division (Time limit: M04)
12.02.2015Reply to a communication from the examining division
03.02.2016Communication of intention to grant the patent
27.05.2016Fee for grant paid
27.05.2016Fee for publishing/printing paid
27.05.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  03.11.2014
Opposition(s)07.04.2017No opposition filed within time limit [2017/24]
Fees paidRenewal fee
16.12.2009Renewal fee patent year 03
15.12.2010Renewal fee patent year 04
12.12.2011Renewal fee patent year 05
11.12.2012Renewal fee patent year 06
12.12.2013Renewal fee patent year 07
11.12.2014Renewal fee patent year 08
10.12.2015Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU21.12.2007
AT06.07.2016
BE06.07.2016
CY06.07.2016
CZ06.07.2016
DK06.07.2016
EE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
MC06.07.2016
NL06.07.2016
PL06.07.2016
RO06.07.2016
SE06.07.2016
SI06.07.2016
SK06.07.2016
TR06.07.2016
BG06.10.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
IE21.12.2016
LU21.12.2016
MT21.12.2016
CH31.12.2016
LI31.12.2016
[2018/43]
Former [2018/29]HU21.12.2007
AT06.07.2016
BE06.07.2016
CY06.07.2016
CZ06.07.2016
DK06.07.2016
EE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
MC06.07.2016
NL06.07.2016
PL06.07.2016
RO06.07.2016
SE06.07.2016
SI06.07.2016
SK06.07.2016
TR06.07.2016
BG06.10.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
IE21.12.2016
LU21.12.2016
CH31.12.2016
LI31.12.2016
Former [2018/28]HU21.12.2007
AT06.07.2016
BE06.07.2016
CY06.07.2016
CZ06.07.2016
DK06.07.2016
EE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
MC06.07.2016
NL06.07.2016
PL06.07.2016
RO06.07.2016
SE06.07.2016
SI06.07.2016
SK06.07.2016
BG06.10.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
IE21.12.2016
LU21.12.2016
CH31.12.2016
LI31.12.2016
Former [2017/49]AT06.07.2016
BE06.07.2016
CZ06.07.2016
DK06.07.2016
EE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
MC06.07.2016
NL06.07.2016
PL06.07.2016
RO06.07.2016
SE06.07.2016
SI06.07.2016
SK06.07.2016
BG06.10.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
IE21.12.2016
LU21.12.2016
CH31.12.2016
LI31.12.2016
Former [2017/45]AT06.07.2016
BE06.07.2016
CZ06.07.2016
DK06.07.2016
EE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
MC06.07.2016
NL06.07.2016
PL06.07.2016
RO06.07.2016
SE06.07.2016
SI06.07.2016
SK06.07.2016
BG06.10.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
Former [2017/37]AT06.07.2016
BE06.07.2016
CZ06.07.2016
DK06.07.2016
EE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
NL06.07.2016
PL06.07.2016
RO06.07.2016
SE06.07.2016
SI06.07.2016
SK06.07.2016
BG06.10.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
Former [2017/31]AT06.07.2016
BE06.07.2016
CZ06.07.2016
DK06.07.2016
EE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
NL06.07.2016
PL06.07.2016
RO06.07.2016
SE06.07.2016
SK06.07.2016
BG06.10.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
Former [2017/13]AT06.07.2016
BE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
LV06.07.2016
NL06.07.2016
PL06.07.2016
SE06.07.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
Former [2017/11]AT06.07.2016
BE06.07.2016
ES06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
NL06.07.2016
PL06.07.2016
SE06.07.2016
GR07.10.2016
IS06.11.2016
PT07.11.2016
Former [2017/10]BE06.07.2016
FI06.07.2016
IT06.07.2016
LT06.07.2016
NL06.07.2016
PL06.07.2016
SE06.07.2016
IS06.11.2016
Former [2017/09]FI06.07.2016
IT06.07.2016
LT06.07.2016
NL06.07.2016
Former [2017/07]LT06.07.2016
Documents cited:Search[IY]  - "SubName: Full=Hepatopoietin PCn127; GEDDD", UniProt, (20060711), Database accession no. Q1AHP8, URL: EBI, XP002598225 [I] 1,2 * the whole document * [Y] 3-5
 [IY]  - "Homo sapiens hepatopoietin PCn127 mRNA, complete cds.", EMBL, (20060607), Database accession no. DQ083510, URL: EBI, XP002598226 [I] 1,2 * the whole document * [Y] 3-5
 [Y]  - GATZIDOU ELISAVET ET AL, Insights on augmenter of liver regeneration cloning and function., WORLD JOURNAL OF GASTROENTEROLOGY : WJG 21 AUG 2006 LNKD- PUBMED:16937489, VOL. 12, NR. 31, PAGE(S) 4951 - 4958, (20060821), ISSN 1007-9327, XP002598227 [Y] 3-5 * the whole document *
 [T]  - CUI CHUN-PING ET AL, Isolation and functional identification of a novel human hepatic growth factor: hepatopoietin Cn., HEPATOLOGY (BALTIMORE, MD.) MAR 2008 LNKD- PUBMED:18306214, VOL. 47, NR. 3, PAGE(S) 986 - 995, (200803), ISSN 1527-3350, XP002598228 [T] 1-5 * the whole document *

DOI:   http://dx.doi.org/10.1002/HEP.22126
International search[XP]CN1896100  (RADIOCTIVE AND RADIANT MEDICAL [CN])
 [X]  - CUI C.P. ET AL., GENBANK, (20060607), Database accession no. (AAZ31261), XP008111110
 [X]  - CUI C.P. ET AL., GENBANK, (20060607), Database accession no. (DQ083510), XP008111109
 [X]  - CHEN T.H. ET AL., "Structure of pp32, an Acidic Nuclear Protein Which Inhibits Oncogene-induced Formation of Transformed Foci", MOLECULAR BIOLOGY OF THE CELL, (199612), vol. 7, no. 12, pages 2045 - 2056, XP000916325
 [Y]  - DU S.J. ET AL., "Progress in Research on the Family of Leucine-Rich Acidic Nuclear Protein", BULL. ACAD. MIL. MED. SCI., (200608), vol. 30, no. 4, pages 369 - 372, XP008125285
by applicantUS5440022
 US5550037
    - BLOMQUIST K ET AL., "Growth stimulation in the liver and tumour development following intraperitoneal injections of liver homogenates in the rat.", ACTA PATHOL MICROBIOL SCAND, (1957), vol. 121, pages 375 - 382
    - LABRECQUE DR; PESCH LA., "Preparation and partial characterization of hepatic regeneration stimulator substance from rat liver", J PHYSIOL, (1975), vol. 248, no. 3, pages 273 - 284
    - HAGIYA M; FRANCAVILLA A; POLIMENO L ET AL., "Cloning and sequence analysis of the rat augmentor of liver regeneration(ALR)gene: expression of biologically active recombinant ALR and demonstration of tissue distribution", PNAS, (1995), vol. 92, no. 7, pages 3076 - 3080
    - MATSUOKA K; TAOKA M; SATOZAWA N ET AL., "A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neuron", PROC NATL ACAD SCI USA, (1994), vol. 91, no. 21, pages 9670 - 9674
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    - BRODY JR; KADKOL SS; MAHMOUD MA ET AL., "Identification of sequences required for inhibition of oncogene-mediated transformation by pp32", J BIOL CHEM, (1999), vol. 274, no. 29, doi:doi:10.1074/jbc.274.29.20053, pages 20053 - 20055, XP002303700

DOI:   http://dx.doi.org/10.1074/jbc.274.29.20053
    - CHEN TH; BRODY JR; ROMANTSEV FE ET AL., "Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci", MOL BIOL CELL, (1996), vol. 7, no. 12, pages 2045 - 2056
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DOI:   http://dx.doi.org/10.1021/bi960581y
    - BRENNAN CM; GALLOUZI IE; STEITZ JA., "Protein ligands to HuR modulate its interaction with target mRNAs in vivo", J CELL BIOL, (2000), vol. 151, no. 1, doi:doi:10.1083/jcb.151.1.1, pages 1 - 14, XP002230286

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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.