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EP2125008

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Extract from the Register of European Patents

EP About this file: EP2125008

EP2125008 - METHOD FOR TREATING PAIN OR OPIOID DEPENDENCE USING A SPECIFIC TYPE OF NON-OPIOID AGENT IN COMBINATION WITH A SELECTIVE EXCITATORY-OPIOID-RECEPTOR INACTIVATOR [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 14.09.2012 Database last updated on 07.10.2024
Most recent event Tooltip	14.09.2012	Application deemed to be withdrawn	published on 17.10.2012 [2012/42]
Applicant(s)	For all designated states Albert Einstein College of Medicine of Yeshiva University 1300 Morris Park Avenue Bronx, NY 10467 / US
	[N/P]
Former [2009/49]	For all designated states Albert Einstein College Of Medecine Of Yeshiva University 1300 Morris Park Avenue Bronx, NY 10467 / US
Inventor(s)	01 / CRAIN, Stanley M. 2472 Pine Hurst Ct. State College, PA 16803 / US
	02 / SHEN, Ke-Fei 144-30 Sanford Avenue Apt. 6J Flushing, NY 11355 / US
	[2009/49]
Representative(s)	Paemen, Liesbet R.J., et al De Clercq & Partners cvba Edgard Gevaertdreef 10 a 9830 Sint-Martens-Latem / BE
	[N/P]
Former [2009/49]	Paemen, Liesbet R.J., et al De Clercq, Brants & Partners E. Gevaertdreef 10 A 9830 Sint-Martens-Latem / BE
Application number, filing date	07867224.3	12.10.2007
	[2009/49]
	WO2007US21836
Priority number, date	US20060855775P	01.11.2006 Original published format: US 855775 P
	[2009/49]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2008060381
	Date:	22.05.2008
	Language:	EN
	[2008/21]
	Type:	A2 Application without search report
	No.:	EP2125008
	Date:	02.12.2009
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 22.05.2008 takes the place of the publication of the European patent application.
	[2009/49]
Search report(s)	International search report - published on:	US	27.11.2008
	(Supplementary) European search report - dispatched on:	EP	26.02.2010
Classification	IPC:	A61K39/106, A61K31/44, A61K31/19, A61K31/557, A01N43/42, A01N37/08, A01N53/00	[2009/49]
	CPC:	A61K31/198 (EP,US); A61K31/4015 (EP,US); A61K45/06 (EP,US); A61P29/00 (EP); A61P29/02 (EP); Y02A50/30 (US)
	C-Set:	A61K31/198, A61K2300/00 (EP,US); A61K31/4015, A61K2300/00 (US,EP)
Designated contracting states	AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR [2009/49]
Title	German:	VERFAHREN ZUR BEHANDLUNG VON SCHMERZEN ODER OPIOID-ABHÄNGIGKEIT MIT EINER BESTIMMTEN ART VON NICHT-OPIOID-MITTEL IN KOMBINATION MIT EINEM SELEKTIVEN EXZITATORISCHEN OPIOID-REZEPTOR-INAKTIVATOR	[2009/49]
	English:	METHOD FOR TREATING PAIN OR OPIOID DEPENDENCE USING A SPECIFIC TYPE OF NON-OPIOID AGENT IN COMBINATION WITH A SELECTIVE EXCITATORY-OPIOID-RECEPTOR INACTIVATOR	[2009/49]
	French:	PROCEDE POUR TRAITER UNE DOULEUR OU UNE DEPENDANCE AUX OPIOIDES EN UTILISANT UN TYPE SELECTIF D'AGENT NON OPIOIDE EN COMBINAISON UN INACTIVATEUR DE RECEPTEUR OPIOEIDE A EXCITATION SELECTIVE	[2009/49]
Entry into regional phase	22.09.2009	National basic fee paid
	22.09.2009	Search fee paid
	22.09.2009	Designation fee(s) paid
	22.09.2009	Examination fee paid
Examination procedure	22.09.2009	Amendment by applicant (claims and/or description)
	22.09.2009	Examination requested [2009/49]
	22.06.2010	Despatch of a communication from the examining division (Time limit: M06)
	08.04.2011	Reply to a communication from the examining division
	01.05.2012	Application deemed to be withdrawn, date of legal effect [2012/42]
	04.06.2012	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2012/42]
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 22.06.2010
Request for further processing for:	The application is deemed to be withdrawn due to failure to reply to the examination report
	08.04.2011	Request for further processing filed
	08.04.2011	Full payment received (date of receipt of payment) Request granted
	20.04.2011	Decision despatched
	22.09.2009	Request for further processing filed
	22.09.2009	Full payment received (date of receipt of payment) Request granted
	15.10.2009	Decision despatched
	The application is deemed to be withdrawn due to non-payment of the search fee
	22.09.2009	Request for further processing filed
	22.09.2009	Full payment received (date of receipt of payment) Request granted
	15.10.2009	Decision despatched
	22.09.2009	Request for further processing filed
	22.09.2009	Full payment received (date of receipt of payment) Request granted
	15.10.2009	Decision despatched
	The application is deemed to be withdrawn due to non-payment of the filing fee
	22.09.2009	Request for further processing filed
	22.09.2009	Full payment received (date of receipt of payment) Request granted
	15.10.2009	Decision despatched
	The application is deemed to be withdrawn due to non-payment of the examination fee
	22.09.2009	Request for further processing filed
	22.09.2009	Full payment received (date of receipt of payment) Request granted
	15.10.2009	Decision despatched
	The application is deemed to be withdrawn due to non-payment of designation fees TR, SK, SI, SE, RO, PT, PL, NL, MT, MC, LV, LU, LT, IT, IS, IE, HU, GR, GB, FR, FI, ES, EE, DK, DE, CZ, CY, CH, BG, BE, AT
	22.09.2009	Request for further processing filed
	22.09.2009	Full payment received (date of receipt of payment) Request granted
	15.10.2009	Decision despatched
Fees paid	Renewal fee
	22.09.2009	Renewal fee patent year 03
	30.03.2011	Renewal fee patent year 04
	Penalty fee
	Additional fee for renewal fee
	31.10.2010	04 M06 Fee paid on 30.03.2011
	31.10.2011	05 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X]US5585348 (CRAIN STANLEY M [US], et al) [X] 1,3,13-15 * claims 1,2,7,8 *;
		[I]WO02076388 (EINSTEIN COLL MED [US]) [I] 1-15 * paragraphs [0095] , [0096] , [0099] , [0101] *;
		[XI] - MAMIYA T ET AL, "Involvement of cyclic AMP systems in morphine physical dependence in mice: prevention of development of morphine dependence by rolipram, a phosphodiesterase 4 inhibitor", BRITISH JOURNAL OF PHARMACOLOGY, NATURE PUBLISHING GROUP, BASINGSTOKE, HANTS, (20010301), vol. 132, no. 5, ISSN 0007-1188, pages 1111 - 1117, XP002426073 [X] 1-5,12-13 * page 1111, column r, paragraph l * * page 1113, column l, paragraph 3 * * page 1114, column r * [I] 11,14 DOI: http://dx.doi.org/10.1038/sj.bjp.0703912
		[XI] - AINHOA BILBAO ET AL, "Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice", PSYCHOPHARMACOLOGY, SPRINGER, BERLIN, DE, (20060401), vol. 185, no. 2, ISSN 1432-2072, pages 160 - 168, XP019326835 [X] 2,4,6-7,9-10,12-13 * page 163, paragraph l * * abstract * [I] 1-14 DOI: http://dx.doi.org/10.1007/s00213-005-0284-0
		[I] - TOKUYAMA SHOGO ET AL, Direct evidence for a role of glutamate in the expression of the opioid withdrawal syndrome, EUROPEAN JOURNAL OF PHARMACOLOGY, VOL. 295, NR. 2-3, PAGE(S) 123-129, (1996), ISSN 0014-2999, XP009129788 [I] 1-15 * page 125, column r - page 127, column l, paragraph 2 * * page 128, column l, paragraph 3 *
	International search	[Y]US6270979 (SADEE WOLFGANG [US]);
		[Y]US6331543 (GARVEY DAVID S [US], et al);
		[X]WO2008008380 (UNIV MINNESOTA [US], et al);
		[Y]US7405207 (LEONARD SHERRY A [US], et al);
		[Y] - CHEN ET AL., "Cholera toxin-B subunit blocks excitatory opioid receptor-mediated hyperalgesic effects in mice, thereby unmasking potent opioid analgesia and attenuating opioid tolerance/dependence", BRAIN RESEARCH, (2001), vol. 919, pages 20 - 30, XP008113907 DOI: http://dx.doi.org/10.1016/S0006-8993(01)02990-0

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