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Extract from the Register of European Patents

EP About this file: EP2089047

EP2089047 - COMPOSITIONS AND METHODS FOR CARDIAC TISSUE PROTECTION AND REGENERATION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.09.2013
Database last updated on 19.10.2024
Most recent event   Tooltip01.07.2016Lapse of the patent in a contracting state
New state(s): IS		published on 03.08.2016  [2016/31]
Applicant(s)For all designated states
3D Matrix, Inc.
12 Toxteth Street
Brookline MA 02445 / US
[2009/34]
Inventor(s)01 / SPIRIO, Lisa
45 Cary Avenue
Lexington, MA 02421 / US
02 / CHU, Zen
P.O. Box 425025
Cambridge, MA 02142 / US
 [2009/34]
Representative(s)Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
[N/P]
Former [2013/17]Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP 20 Red Lion Street London
WC1R 4PJ / GB
Former [2009/34]Hollywood, Jane Constance, et al
Kilburn & Strode LLP 20 Red Lion Street
London WC1R 4PJ / GB
Application number, filing date07867700.211.12.2007
[2009/34]
WO2007US25271
Priority number, dateUS20060869437P11.12.2006         Original published format: US 869437 P
[2009/34]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2008073395
Date:19.06.2008
Language:EN
[2008/25]
Type: A2 Application without search report 
No.:EP2089047
Date:19.08.2009
Language:EN
The application published by WIPO in one of the EPO official languages on 19.06.2008 takes the place of the publication of the European patent application.
[2009/34]
Type: B1 Patent specification 
No.:EP2089047
Date:14.11.2012
Language:EN
[2012/46]
Search report(s)International search report - published on:EP06.11.2008
ClassificationIPC:A61K38/10, A61P9/00, A61P19/02, A61P25/28, A61P7/00, A61P35/00
[2009/34]
CPC:
A61K38/10 (EP,US); A61K33/00 (US); A61P11/06 (EP);
A61P19/02 (EP); A61P25/28 (EP); A61P31/04 (EP);
A61P35/00 (EP); A61P43/00 (EP); A61P7/00 (EP);
A61P9/00 (EP); A61P9/04 (EP); A61P9/10 (EP);
A61P9/12 (EP) (-)
C-Set:
A61K38/10, A61K2300/00 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2009/34]
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUM SCHUTZ UND ZUR REGENERATION VON HERZGEWEBE[2009/34]
English:COMPOSITIONS AND METHODS FOR CARDIAC TISSUE PROTECTION AND REGENERATION[2009/34]
French:COMPOSITIONS ET PROCÉDÉS VISANT À PROTÉGER ET À RÉGÉNÉRER UN TISSU CARDIAQUE[2009/34]
Entry into regional phase04.06.2009National basic fee paid 
04.06.2009Designation fee(s) paid 
04.06.2009Examination fee paid 
Examination procedure04.06.2009Examination requested  [2009/34]
20.08.2009Amendment by applicant (claims and/or description)
07.10.2009Despatch of a communication from the examining division (Time limit: M06)
21.05.2010Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
30.07.2010Reply to a communication from the examining division
29.05.2012Cancellation of oral proceeding that was planned for 12.06.2012
12.06.2012Date of oral proceedings (cancelled)
20.06.2012Communication of intention to grant the patent
25.09.2012Fee for grant paid
25.09.2012Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  07.10.2009
Opposition(s)15.08.2013No opposition filed within time limit [2013/43]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
02.08.2010Request for further processing filed
02.08.2010Full payment received (date of receipt of payment)
Fees paidRenewal fee
25.01.2010Renewal fee patent year 03
27.12.2010Renewal fee patent year 04
27.12.2011Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.12.200903   M06   Fee paid on   25.01.2010
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU11.12.2007
AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
IS14.11.2012
LT14.11.2012
LV14.11.2012
MT14.11.2012
NL14.11.2012
PL14.11.2012
RO14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
TR14.11.2012
IE11.12.2012
LU11.12.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
[2016/31]
Former [2014/34]HU11.12.2007
AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
MT14.11.2012
NL14.11.2012
PL14.11.2012
RO14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
TR14.11.2012
IE11.12.2012
LU11.12.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2014/27]AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
MT14.11.2012
NL14.11.2012
PL14.11.2012
RO14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
TR14.11.2012
IE11.12.2012
LU11.12.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2014/21]AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
MT14.11.2012
NL14.11.2012
PL14.11.2012
RO14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
TR14.11.2012
IE11.12.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2013/51]AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
MT14.11.2012
NL14.11.2012
PL14.11.2012
RO14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
IE11.12.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2013/47]AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
NL14.11.2012
PL14.11.2012
RO14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
IE11.12.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2013/37]AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
NL14.11.2012
PL14.11.2012
RO14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2013/35]AT14.11.2012
BE14.11.2012
CY14.11.2012
CZ14.11.2012
EE14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
SI14.11.2012
SK14.11.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2013/34]AT14.11.2012
BE14.11.2012
CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
SI14.11.2012
MC31.12.2012
BG14.02.2013
GR15.02.2013
PT14.03.2013
Former [2013/33]AT14.11.2012
BE14.11.2012
CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
SI14.11.2012
MC31.12.2012
GR15.02.2013
PT14.03.2013
Former [2013/31]AT14.11.2012
BE14.11.2012
CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
SI14.11.2012
GR15.02.2013
PT14.03.2013
Former [2013/28]BE14.11.2012
CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
SI14.11.2012
GR15.02.2013
PT14.03.2013
Former [2013/27]BE14.11.2012
CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
SI14.11.2012
GR15.02.2013
Former [2013/26]CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
SI14.11.2012
GR15.02.2013
Former [2013/24]CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
GR15.02.2013
Former [2013/23]CY14.11.2012
FI14.11.2012
LT14.11.2012
LV14.11.2012
PL14.11.2012
SE14.11.2012
Former [2013/22]FI14.11.2012
LT14.11.2012
SE14.11.2012
Former [2013/21]LT14.11.2012
SE14.11.2012
Former [2013/20]LT14.11.2012
Cited inInternational search[X]WO2006116524  (MASSACHUSETTS INST TECHNOLOGY [US], et al) [X] 1-11,22-27 * page 14, paragraphs 2,3 - page 15, paragraphs 1,2 * * page 18, paragraph 2 * * page 24, paragraph L * * page 30, paragraphs 2,3 * * page 40, lines 26-30 * * page 41, paragraphs 6,7 * * pages 59-63; examples 1-6 *;
 [X]US2006148703  (LEE RICHARD T [US], et al) [X] 1-11,22-27 * claims 1,13,17,20 * * page 1, paragraph 6 * * page 2, paragraph 9 *;
 [X]WO2005014615  (MASSACHUSETTS INST TECHNOLOGY [US], et al) [X] 1-11,22-27 * page 4, paragraph 10 * * pages 7-8, paragraph 29; figure 13 * * page 28, paragraph 2 * * page 72, paragraphs 213-215 * * pages 92-93, paragraph 284; figure 15 * * page 91, paragraph 279 *
 [X]  - HSIEH PATRICK C H ET AL, "Local controlled intramyocardial delivery of platelet-derived growth factor improves postinfarction ventricular function without pulmonary toxicity.", CIRCULATION 15 AUG 2006, (20060815), vol. 114, no. 7, ISSN 1524-4539, pages 637 - 644, XP002485917 [X] 1-11,22-27 * page 638, column L, paragraph 2 * * figures 1,2 *

DOI:   http://dx.doi.org/10.1161/CIRCULATIONAHA.106.639831
Examination   - HSIEH P C H ET AL, "Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers", JOURNAL OF CLINICAL INVESTIGATION, AMERICAN SOCIETY FOR CLINICAL INVESTIGATION, US, (20060101), vol. 116, no. 1, doi:10.1172/JCI25878, ISSN 0021-9738, pages 237 - 248, XP008084972

DOI:   http://dx.doi.org/10.1172/JCI25878
by applicantUS2004242469
 US2006084607
    - ASSMUS B; HONOLD J; SCHACHINGER V; BRITTEN MB; FISCHER-RASOKAT U; LEHMANN R; TEUPE C; PISTORIUS K; MARTIN H; ABOLMAALI ND, "Transcoronary transplantation of progenitor cells after myocardial infarction", NENGLJMED, (2006), vol. 355, pages 1222 - 1232
    - BRAUNWALD E; BRISTOW MR., "Congestive heart failure: fifty years of progress", CIRCULATION, (2000), vol. 102, pages IV14 - 23
    - BRUNNER F; MAIER R; ANDREW P; WOLKART G; ZECHNER R; MAYER B., "Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase", CARDIOVASC RES, (2003), vol. 57, pages 55 - 62
    - CHIEN KR, "Lost and found: cardiac stem cell therapy revisited", J CLIN INVEST, (2006), vol. 1, no. 16, pages 1838 - 1840
    - CHUNG T; EMMETT L; KHOURY V; LAU GT; ELSIK M; FOO F; ALLMAN KC; KRITHARIDES L., "Atrial and ventricular echocardiographic correlates of the extent of pulmonary embolism in the elderly", JAM SOC ECHOCARDIOGR, (2006), vol. 19, doi:doi:10.1016/j.echo.2005.09.012, pages 347 - 353, XP005491978

DOI:   http://dx.doi.org/10.1016/j.echo.2005.09.012
    - DARLAND DC; D'AMORE PA., "Cell-cell interactions in vascular development", CURR TOP DEV BIOL, (2001), doi:doi:10.1016/S0070-2153(01)52010-4, pages 107 - 149, XP009036573

DOI:   http://dx.doi.org/10.1016/S0070-2153(01)52010-4
    - DAVIS ME; HSIEH PC; TAKAHASHI T; SONG Q; ZHANG S; KAMM RD; GRODZINSKY AJ; ANVERSA P; LEE RT, "Local myocardial insulin-like growth factor 1 (IGF-I) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction", PROC NATL ACAD SCI USA, (2006), vol. 103, doi:doi:10.1073/pnas.0602877103, pages 8155 - 8160, XP009103986

DOI:   http://dx.doi.org/10.1073/pnas.0602877103
    - DAVIS ME; MOTION JP; NARMONEVA DA; TAKAHASHI T; HAKUNO D; KAMM RD; ZHANG S; LEE RT, "Injectable self-assembling peptide nanofibers create intramyocardial microenvironments for endothelial cells", CIRCULATION, (2005), vol. 111, doi:doi:10.1161/01.CIR.0000153847.47301.80, pages 442 - 450, XP002398331

DOI:   http://dx.doi.org/10.1161/01.CIR.0000153847.47301.80
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.