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EP2076116
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EP About this file: EP2076116
| EP2076116 - COMPOSITIONS, METHODS, AND DEVICES FOR TREATING LIVER DISEASE [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 10.04.2015 Database last updated on 03.09.2024 | Most recent event Tooltip | 10.04.2015 | Application deemed to be withdrawn | published on 13.05.2015 [2015/20] | Applicant(s) | For all designated states The General Hospital Corporation 55 Fruit Street Boston, MA 02114 / US | For all designated states Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge MA 02142 / US | [2009/28] | Inventor(s) | 01 /
YARMUSH, Martin L. 164 Ward Street Newton, Massachusetts 02459 / US | 02 /
PAREKKADAN, Biju 26 Inman Street Cambridge, Massachusetts 02139 / US | [2009/28] | Representative(s) | Boult Wade Tennant LLP Salisbury Square House 8 Salisbury Square London EC4Y 8AP / GB | [N/P] |
| Former [2014/02] | Boult Wade Tennant Verulam Gardens 70 Gray's Inn Road London WC1X 8BT / GB | ||
| Former [2009/28] | Baldock, Sharon Claire BOULT WADE TENNANT Verulam Gardens 70 Gray's Inn Road London WC1X 8BT / GB | Application number, filing date | 07868423.0 | 11.10.2007 | [2009/28] | WO2007US81142 | Priority number, date | US20060850778P | 11.10.2006 Original published format: US 850778 P | US20060851234P | 12.10.2006 Original published format: US 851234 P | US20070923138P | 12.04.2007 Original published format: US 923138 P | US20070995316P | 26.09.2007 Original published format: US 995316 P | [2009/28] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2008060788 | Date: | 22.05.2008 | Language: | EN | [2008/21] | Type: | A2 Application without search report | No.: | EP2076116 | Date: | 08.07.2009 | Language: | EN | The application published by WIPO in one of the EPO official languages on 22.05.2008 takes the place of the publication of the European patent application. | [2009/28] | Search report(s) | International search report - published on: | US | 04.12.2008 | (Supplementary) European search report - dispatched on: | EP | 08.03.2010 | Classification | IPC: | A01N1/00 | [2009/28] | CPC: |
A61M1/3472 (EP,US);
A61K35/28 (US);
A61M1/3489 (EP,US);
A61M1/3687 (EP,US);
A61M1/3689 (EP,US);
A61P1/16 (EP);
A61P37/00 (EP);
C12M29/16 (US);
C12N5/0663 (US);
C12N5/067 (EP,US);
G01N33/5067 (US);
G01N33/5073 (US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR [2009/28] | Title | German: | ZUSAMMENSETZUNGEN, VERFAHREN UND VORRICHTUNGEN ZUR BEHANDLUNG VON LEBERERKRANKUNGEN | [2009/28] | English: | COMPOSITIONS, METHODS, AND DEVICES FOR TREATING LIVER DISEASE | [2009/28] | French: | COMPOSITIONS, PROCÉDÉS, ET DISPOSITIFS DESTINÉS À TRAITER LES MALADIES HÉPATIQUES | [2009/28] | Entry into regional phase | 11.05.2009 | National basic fee paid | 11.05.2009 | Search fee paid | 11.05.2009 | Designation fee(s) paid | 11.05.2009 | Examination fee paid | Examination procedure | 11.05.2009 | Examination requested [2009/28] | 26.06.2009 | Amendment by applicant (claims and/or description) | 01.07.2010 | Despatch of a communication from the examining division (Time limit: M06) | 27.04.2011 | Reply to a communication from the examining division | 11.01.2012 | Despatch of a communication from the examining division (Time limit: M06) | 23.07.2012 | Reply to a communication from the examining division | 19.03.2013 | Despatch of a communication from the examining division (Time limit: M06) | 20.12.2013 | Reply to a communication from the examining division | 16.07.2014 | Despatch of a communication from the examining division (Time limit: M04) | 27.11.2014 | Application deemed to be withdrawn, date of legal effect [2015/20] | 05.01.2015 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2015/20] | Divisional application(s) | EP12176014.4 / EP2578081 | EP12176015.1 Application deemed to be withdrawn : 14.08.2012 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 01.07.2010 | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 20.12.2013 | Request for further processing filed | 20.12.2013 | Full payment received (date of receipt of payment) Request granted | 14.01.2014 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the examination report | 27.04.2011 | Request for further processing filed | 27.04.2011 | Full payment received (date of receipt of payment) Request granted | 16.05.2011 | Decision despatched | Fees paid | Renewal fee | 26.10.2009 | Renewal fee patent year 03 | 25.10.2010 | Renewal fee patent year 04 | 25.10.2011 | Renewal fee patent year 05 | 25.10.2012 | Renewal fee patent year 06 | 28.10.2013 | Renewal fee patent year 07 | 27.10.2014 | Renewal fee patent year 08 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [Y]WO0078932 (GEN HOSPITAL CORP [US], et al) [Y] 1-10 * the whole document *; | [Y]WO03104411 (MAYO FOUNDATION [US], et al) [Y] 1-10 * the whole document *; | [A]EP1669441 (RENOMEDIX INST INC [JP]) [A] 1-10 * the whole document *; | [PX] - PAREKKADAN BIJU ET AL, "Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure (E941)", PLOS ONE, (20070926), vol. 2, no. 9, ISSN 1932-6203, pages 1 - 6, XP002566967 [PX] 1-10 * the whole document * DOI: http://dx.doi.org/10.1371/JOURNAL.PONE.0000941 | [PY] - PAREKKADAN ET AL, "Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (20070530), vol. 363, no. 2, ISSN 0006-291X, pages 247 - 252, XP022278072 [PY] 1-10 * the whole document * DOI: http://dx.doi.org/10.1016/j.bbrc.2007.05.150 | [Y] - ISODA KATSUHIRO ET AL, "Maintenance of hepatocyte functions by coculture with bone marrow stromal cells", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, (200405), vol. 97, no. 5, ISSN 1389-1723, pages 343 - 346, XP002566968 [Y] 1-10 * the whole document * | [Y] - SHINODA MASAHIRO ET AL, "Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist", TISSUE ENGINEERING, (200605), vol. 12, no. 5, ISSN 1076-3279, pages 1313 - 1323, XP002566969 [Y] 1-10 * the whole document * DOI: http://dx.doi.org/10.1089/ten.2006.12.1313 | [AD] - ZHAO DONG-CHANG ET AL, "Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats.", WORLD JOURNAL OF GASTROENTEROLOGY : WJG 14 JUN 2005, (20050614), vol. 11, no. 22, ISSN 1007-9327, pages 3431 - 3440, XP002566970 [AD] 1-10 * the whole document * | [AD] - SAKAIDA ISAO ET AL, "Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice", HEPATOLOGY, (200412), vol. 40, no. 6, ISSN 0270-9139, pages 1304 - 1311, XP002566971 [AD] 1-10 * the whole document * DOI: http://dx.doi.org/10.1002/HEP.20452 | [AD] - FANG BAIJUN ET AL, "Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice", TRANSPLANTATION, WILLIAMS AND WILKINS, BALTIMORE, MD, US, (20040715), vol. 78, no. 1, ISSN 0041-1337, pages 83 - 88, XP009128800 [AD] 1-10 * the whole document * DOI: http://dx.doi.org/10.1097/01.TP.0000128326.95294.14 | [T] - YAGI HIROSHI ET AL, "Long-Term Superior Performance of a Stem Cell/Hepatocyte Device for the Treatment of Acute Liver Failure", TISSUE ENGINEERING PART A, (200911), vol. 15, no. 11, ISSN 1937-3341, pages 3377 - 3388, XP009128318 [T] 1-10 * the whole document * DOI: http://dx.doi.org/10.1089/ten.tea.2008.0681 | International search | [Y]US5605835 (HU WEI-SHOU [US], et al); | [Y] - TAKEDA ET AL., "Availability of Bone Marrow Stromal Cells in Three-Dimensional Coculture with Hepatocyte and Transplantation into Liver-Damaged Mice", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, (2005), vol. 100, no. 1, pages 77 - 81, XP005046482 DOI: http://dx.doi.org/10.1263/jbb.100.77 | [YT] - QIHAO ET AL., "Spheroid Formation and Differentiation into Hepatocyte-Like Cells of Rat Mesenchymal Stem Cell Induced by Co-Culture with Liver Cells", DNA AND CELL BIOLOGY, (2007), vol. 26, no. 7, pages 497 - 503, XP008109874 DOI: http://dx.doi.org/10.1089/dna.2006.0562 |