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EP2114940
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EP About this file: EP2114940
| EP2114940 - AZA-ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 613 [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 02.03.2012 Database last updated on 15.06.2024 | Most recent event Tooltip | 02.03.2012 | Application deemed to be withdrawn | published on 04.04.2012 [2012/14] | Applicant(s) | For all designated states AstraZeneca AB 151 85 Södertälje / SE | [2009/46] | Inventor(s) | 01 /
SLASSI, Abdelmalik 4780 Fulwell Road Mississauga, Ontario L5M 7J7 / CA | 02 /
ISAAC, Methvin 17 Reynolds Ave. Brampton, Ontario L6P 2C1 / CA | 03 /
CLAYTON, Joshua 1321 Ashwood Terrace Oakville, Ontario L6M 4A7 / CA | 04 /
EGLE, Ian 1700 Eglinton Ave. E.Ste 318 North York Ontario M4A 2X4 / CA | 05 /
JOSEPH, Babu 1112 Goodson Cres Oakville, Ontario L6H 4A5 / CA | 06 /
MA, Fupeng 1 Oak Grove Ave. Unit 315 Melrose, MA 02176 / US | [2009/47] |
| Former [2009/46] | 01 /
SLASSI, Abdelmalik 4780 Fulwell Road Mississauga, Ontario L5M 7J7 / CA | ||
| 02 /
ISAAC, Methvin 17 Reynolds Ave. Brampton, Ontario L6P 2C1 / CA | |||
| 03 /
CLAYTON, Joshua 1156 Pilgrims Way Oakville, Ontario L6M 1H1 / CA | |||
| 04 /
EGLE, Ian 36 Webster Way Georgetown, Ontario L7G 5J7 / CA | |||
| 05 /
JOSEPH, Babu 1112 Goodson Cres Oakville, Ontario L6H 4A5 / CA | |||
| 06 /
MA, Fupeng 1 Oak Grove Ave. Unit 315 Melrose, MA 02176 / US | Application number, filing date | 08728676.1 | 31.01.2008 | [2009/46] | WO2008US52609 | Priority number, date | US20070900318P | 09.02.2007 Original published format: US 900318 P | [2009/46] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2008100715 | Date: | 21.08.2008 | Language: | EN | [2008/34] | Type: | A1 Application with search report | No.: | EP2114940 | Date: | 11.11.2009 | Language: | EN | The application published by WIPO in one of the EPO official languages on 21.08.2008 takes the place of the publication of the European patent application. | [2009/46] | Search report(s) | International search report - published on: | EP | 21.08.2008 | Classification | IPC: | C07D471/04, A61K31/437, A61P25/00 | [2009/46] | CPC: |
C07D471/04 (EP,US);
A61P1/08 (EP);
A61P13/02 (EP);
A61P21/00 (EP);
A61P25/00 (EP);
A61P25/04 (EP);
A61P25/06 (EP);
A61P25/14 (EP);
A61P25/16 (EP);
A61P25/18 (EP);
A61P25/20 (EP);
A61P25/22 (EP);
A61P25/24 (EP);
A61P25/28 (EP);
A61P25/30 (EP);
A61P27/02 (EP);
A61P27/16 (EP);
A61P29/02 (EP);
A61P31/18 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP)
(-)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2009/46] | Title | German: | AZA-ISOINDOLONE UND IHRE VERWENDUNG ALS METABOTROPE GLUTAMAT-REZEPTOR-POTENTIATOREN - 613 | [2009/46] | English: | AZA-ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 613 | [2009/46] | French: | AZA-ISO-INDOLONES ET LEUR UTILISATION COMME POTENTIATEURS DU RÉCEPTEUR DU GLUTAMATE MÉTABOTROPE - 613 | [2009/46] | Entry into regional phase | 09.09.2009 | National basic fee paid | 09.09.2009 | Designation fee(s) paid | 09.09.2009 | Examination fee paid | Examination procedure | 09.09.2009 | Examination requested [2009/46] | 22.12.2009 | Despatch of a communication from the examining division (Time limit: M06) | 30.06.2010 | Reply to a communication from the examining division | 06.05.2011 | Communication of intention to grant the patent | 17.09.2011 | Application deemed to be withdrawn, date of legal effect [2012/14] | 25.10.2011 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2012/14] | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 22.12.2009 | Fees paid | Renewal fee | 01.02.2010 | Renewal fee patent year 03 | 31.01.2011 | Renewal fee patent year 04 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X]WO9842666 (DAE WOONG PHARMA [KR], et al) [X] 1,8,9 * the whole document *; | [X] - Y YAMAMOTO ET AL., "Synthesis of 2-haloalkylpyridines via Cp*RuCl-catalyzed cycloaddition of 1,6-diynes with alpha-halonitriles", ADV. SYNTH. CATAL., (2005), vol. 347, pages 1913 - 1916, XP002483083 [X] 1-3 * compound 6a, 6e, 6j * DOI: http://dx.doi.org/10.1002/adsc.200505193 | [X] - G DEGUEST ET AL., "One-pot synthesis og 2,3-dihydro-pyrolopyridinones using in situr generated formimines", ORG. LETT., (2006), vol. 8, no. 25, pages 5889 - 5892, XP002483084 [X] 1-3 * compounds 4a, 18 * DOI: http://dx.doi.org/10.1021/ol062577c | [X] - Y YAMAMOTO ET AL., "Ruthenium-catalyzed cycloaddition of 1,6-diynes and nitriles udner mild conditions", CHEM. EUR. J., (2006), vol. 12, pages 5618 - 5631, XP002483085 [X] 1-3 * compounds 24a, 24h, 24k * DOI: http://dx.doi.org/10.1002/chem.200600176 | [X] - PARCHINSKY V Z ET AL, "Practical outcome of azaphthalimide reduction with Zn/AcOH at various temperatures", LETTERS IN ORGANIC CHEMISTRY, BENTHAM SCIENCE PUBLISHERS LTD., HILVERSUM, NL, (20060101), vol. 3, no. 5, ISSN 1570-1786, pages 379 - 383, XP008092364 [X] 1-3 * compound 6a * DOI: http://dx.doi.org/10.2174/157017806776611890 | [X] - RA NADZHAFOVA, "Reaction of ethyl 6-alkyl(aryl)-4-chloromethyl-2-methyl-pyridine-3-carboxylates with ammonia and primary amines", RUSS. J. ORG. CHEM., (2002), vol. 38, no. 1, pages 126 - 128, XP002483086 [X] 1,2,4 * compounds IIIb,c; IVb,c; Vb,c * | [A] - TASLER S ET AL, "Non-competitive inhibitors of metabotropic glutamate receptor 5 (mGluR5)", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, (20050602), vol. 15, no. 11, ISSN 0960-894X, pages 2876 - 2880, XP004906914 [A] 1-15 * the whole document * DOI: http://dx.doi.org/10.1016/j.bmcl.2005.03.089 | by applicant | - SCHOEPP ET AL., TRENDS PHARMACOL. SCI., (1993), vol. 14, no. 13 | - SCHOEPP, NEUROCHEM. INT., (1994), vol. 24, page 439 | - PIN ET AL., NEUROPHARMACOLOGY, (1995), vol. 34, page 1 | - BORDI; UGOLINI, PROG. NEUROBIOL, vol. 59, (1999), page 55, URL: Prog. Neurobiol | - PIN ET AL., EUR. J. PHARMACOL., (1999), vol. 375, pages 277 - 294 | - BASHIR ET AL., NATURE, (1993), vol. 363, page 347 | - BORTOLOTTO ET AL., NATURE, (1994), vol. 368, page 740 | - AIBA ET AL., CELL, (1994), vol. 79, page 365 | - ARAMORI ET AL., NEURON, (1992), vol. 8, page 757 | - TANABE ET AL., NEURON, (1992), vol. 8, page 169 | - MILLER ET AL., J. NEUROSCIENCE, (1995), vol. 15, page 6103 | - BALAZS ET AL., J. NEUROCHEMISTRY, (1997), vol. 69, page 151 |