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Extract from the Register of European Patents

EP About this file: EP2142515

EP2142515 - NITROVINYL-DIAMINE DERIVATIVES AS GLUTAMINYL CYCLASE INHIBITORS [Right-click to bookmark this link]
Former [2010/02]NOVEL INHIBITORS
[2013/42]
StatusNo opposition filed within time limit
Status updated on  30.01.2015
Database last updated on 11.04.2026
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
Probiodrug AG
Weinbergweg 22
06120 Halle/Saale / DE
[2014/13]
Former [2010/02]For all designated states
Probiodrug AG
Weinbergweg 22
06120 Halle/Saale / DE
Inventor(s)01 / BUCHHOLZ, Mirko
Brandenburger Strasse 6
06114 Halle/Saale / DE
02 / HEISER, Ulrich
Franz-Schubert-Strasse 5
06108 Halle/Saale / DE
03 / HAMANN, Antje
Ahornring 45
06184 Dieskau / DE
 [2010/02]
Representative(s)Hoffmann, Matthias, et al
Maikowski & Ninnemann
Patentanwälte
Kurfürstendamm 54-55
10707 Berlin / DE
[2012/29]
Former [2010/02]Hoffmann, Matthias
Probiodrug AG Weinbergweg 22
06120 Halle/Saale / DE
Application number, filing date08736366.918.04.2008
[2010/02]
WO2008EP54717
Priority number, dateUS20070912535P18.04.2007         Original published format: US 912535 P
[2010/02]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008128987
Date:30.10.2008
Language:EN
[2008/44]
Type: A1 Application with search report 
No.:EP2142515
Date:13.01.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 30.10.2008 takes the place of the publication of the European patent application.
[2010/02]
Type: B1 Patent specification 
No.:EP2142515
Date:26.03.2014
Language:EN
[2014/13]
Search report(s)International search report - published on:EP30.10.2008
ClassificationIPC:C07D233/54, A61K31/4164, A61P25/00, C07D405/12
[2010/02]
CPC:
C07D233/61 (EP,US); A61P1/04 (EP); A61P1/18 (EP);
A61P15/08 (EP); A61P17/00 (EP); A61P17/06 (EP);
A61P19/00 (EP); A61P19/02 (EP); A61P25/00 (EP);
A61P25/02 (EP); A61P25/14 (EP); A61P25/16 (EP);
A61P25/18 (EP); A61P25/20 (EP); A61P25/28 (EP);
A61P29/00 (EP); A61P3/00 (EP); A61P3/04 (EP);
A61P35/00 (EP); A61P35/04 (EP); A61P37/00 (EP);
A61P43/00 (EP); A61P5/00 (EP); A61P7/00 (EP);
A61P9/10 (EP); C07D233/64 (EP,US); C07D405/12 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/02]
TitleGerman:NITROVINYL-DIAMIN DERIVATE ALS GLUTAMINYL CYCLASE HEMMER[2013/44]
English:NITROVINYL-DIAMINE DERIVATIVES AS GLUTAMINYL CYCLASE INHIBITORS[2013/42]
French:DERIVES DE NITROVINYL-DIAMINE EN TANT QUE INHIBITEURS DE LA GLUTAMINYL-CYCLASE[2013/44]
Former [2010/02]NEUE INHIBITOREN
Former [2010/02]NOVEL INHIBITORS
Former [2010/02]NOUVEAUX INHIBITEURS
Entry into regional phase04.11.2009National basic fee paid 
04.11.2009Designation fee(s) paid 
04.11.2009Examination fee paid 
Examination procedure04.11.2009Amendment by applicant (claims and/or description)
04.11.2009Examination requested  [2010/02]
15.04.2013Despatch of a communication from the examining division (Time limit: M04)
20.08.2013Reply to a communication from the examining division
17.10.2013Communication of intention to grant the patent
17.02.2014Fee for grant paid
17.02.2014Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.04.2013
Opposition(s)06.01.2015No opposition filed within time limit [2015/10]
Fees paidRenewal fee
24.03.2010Renewal fee patent year 03
11.04.2011Renewal fee patent year 04
16.03.2012Renewal fee patent year 05
12.04.2013Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU18.04.2008
CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
MT26.03.2014
NL26.03.2014
PL26.03.2014
RO26.03.2014
SI26.03.2014
SK26.03.2014
TR26.03.2014
BG26.06.2014
NO26.06.2014
GR27.06.2014
IS26.07.2014
PT28.07.2014
[2016/33]
Former [2016/32]HU18.04.2008
CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
MT26.03.2014
NL26.03.2014
PL26.03.2014
RO26.03.2014
SI26.03.2014
SK26.03.2014
BG26.06.2014
NO26.06.2014
GR27.06.2014
IS26.07.2014
PT28.07.2014
Former [2016/28]CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
MT26.03.2014
NL26.03.2014
PL26.03.2014
RO26.03.2014
SI26.03.2014
SK26.03.2014
BG26.06.2014
NO26.06.2014
GR27.06.2014
IS26.07.2014
PT28.07.2014
Former [2016/16]CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
MT26.03.2014
NL26.03.2014
PL26.03.2014
RO26.03.2014
SI26.03.2014
SK26.03.2014
BG26.06.2014
NO26.06.2014
IS26.07.2014
PT28.07.2014
Former [2015/36]CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
NL26.03.2014
PL26.03.2014
RO26.03.2014
SI26.03.2014
SK26.03.2014
BG26.06.2014
NO26.06.2014
IS26.07.2014
PT28.07.2014
Former [2015/02]CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
NL26.03.2014
PL26.03.2014
RO26.03.2014
SK26.03.2014
BG26.06.2014
NO26.06.2014
IS26.07.2014
PT28.07.2014
Former [2014/50]CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
NL26.03.2014
PL26.03.2014
RO26.03.2014
SK26.03.2014
BG26.06.2014
NO26.06.2014
IS26.07.2014
Former [2014/49]CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
RO26.03.2014
BG26.06.2014
NO26.06.2014
IS26.07.2014
Former [2014/48]CY26.03.2014
CZ26.03.2014
EE26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
BG26.06.2014
NO26.06.2014
Former [2014/47]CY26.03.2014
FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
NO26.06.2014
Former [2014/41]FI26.03.2014
HR26.03.2014
LT26.03.2014
LV26.03.2014
NO26.06.2014
Former [2014/37]FI26.03.2014
LT26.03.2014
NO26.06.2014
Former [2014/36]LT26.03.2014
NO26.06.2014
Cited inInternational search[Y]   BUCHHOLZ MIRKO ET AL: "The first potent inhibitors for human glutaminyl cyclase: Synthesis and structure-activity relationship", JOURNAL OF MEDICINAL CHEMISTRY, USAMERICAN CHEMICAL SOCIETY. WASHINGTON, vol. 49, no. 2, 1 January 2006 (2006-01-01), pages 664 - 677, XP002462493, ISSN: 0022-2623 [Y] 1-24 * page 665 - page 666 *

DOI:   http://dx.doi.org/10.1021/jm050756e
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