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Extract from the Register of European Patents

EP About this file: EP2162137

EP2162137 - METHODS OF TREATING COGNITIVE DISORDERS BY INHIBITION OF GPR12 [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.09.2017
Database last updated on 31.05.2024
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): IS		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Dart NeuroScience LLC
7473 Lusk Boulevard
San Diego, CA 92121 / US
[2013/32]
Former [2010/11]For all designated states
Helicon Therapeutics, Inc.
7473 Lusk Blvd.
San Diego, CA 92121 / US
Inventor(s)01 / PETERS, Marco
340 Play Del Norte
La Jolla, CA 92037 / US
02 / SCOTT, Roderick, E.M.
15127 Canyon Pass
Poway, CA 02964 / US
03 / TULLY, Timothy, P.
819 Seabright Lane
Solana Beach, CA 92075 / US
 [2010/11]
Representative(s)Kirkham, Nicholas Andrew, et al
Graham Watt & Co. LLP
St. Botolph's House
7-9 St. Botolph's Road
Sevenoaks, Kent TN13 3AJ / GB
[2016/47]
Former [2012/49]Kirkham, Nicholas Andrew, et al
Graham Watt & Co. LLP
St. Botolph's House
7-9 St. Botolph's Road
Sevenoaks
Kent TN13 3AJ / GB
Former [2010/11]Becker, Philippe, et al
Cabinet Becker & Associés 25, rue Louis Le Grand
75002 Paris / FR
Application number, filing date08755619.715.05.2008
[2010/11]
WO2008US63804
Priority number, dateUS20070938163P15.05.2007         Original published format: US 938163 P
[2010/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008144453
Date:27.11.2008
Language:EN
[2008/48]
Type: A1 Application with search report 
No.:EP2162137
Date:17.03.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 27.11.2008 takes the place of the publication of the European patent application.
[2010/11]
Type: B1 Patent specification 
No.:EP2162137
Date:23.11.2016
Language:EN
[2016/47]
Search report(s)International search report - published on:US27.11.2008
(Supplementary) European search report - dispatched on:EP10.05.2011
ClassificationIPC:A61K31/713
[2011/23]
CPC:
C12N15/1138 (EP,US); A61K31/70 (KR); A61K39/395 (KR);
A61P25/00 (EP); A61P25/28 (EP); A61P43/00 (EP);
C12N2310/14 (EP,US) (-)
Former IPC [2010/11]A61K31/70
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/47]
Former [2010/11]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:VERFAHREN ZUR BEHANDLUNG VON KOGNITIVEN STÖRUNGEN DURCH HEMMUNG VON GPR12[2010/11]
English:METHODS OF TREATING COGNITIVE DISORDERS BY INHIBITION OF GPR12[2010/11]
French:PROCÉDÉS DE TRAITEMENT DE TROUBLES COGNITIFS PAR INHIBITION DU GPR12[2010/11]
Entry into regional phase09.12.2009National basic fee paid 
09.12.2009Search fee paid 
09.12.2009Designation fee(s) paid 
09.12.2009Examination fee paid 
Examination procedure09.12.2009Examination requested  [2010/11]
29.11.2011Amendment by applicant (claims and/or description)
27.05.2014Despatch of a communication from the examining division (Time limit: M06)
08.12.2014Reply to a communication from the examining division
08.06.2016Communication of intention to grant the patent
10.10.2016Receipt of the translation of the claim(s)
15.10.2016Fee for grant paid
15.10.2016Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  27.05.2014
Opposition(s)24.08.2017No opposition filed within time limit [2017/44]
Fees paidRenewal fee
04.05.2010Renewal fee patent year 03
11.05.2011Renewal fee patent year 04
29.03.2012Renewal fee patent year 05
28.05.2013Renewal fee patent year 06
27.05.2014Renewal fee patent year 07
27.05.2015Renewal fee patent year 08
10.05.2016Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.05.2008
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
TR23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
IS23.03.2017
PT23.03.2017
IE15.05.2017
LU15.05.2017
MT15.05.2017
CH31.05.2017
LI31.05.2017
[2020/33]
Former [2020/15]HU15.05.2008
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
TR23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
IE15.05.2017
LU15.05.2017
MT15.05.2017
CH31.05.2017
LI31.05.2017
Former [2019/46]HU15.05.2008
AT23.11.2016
BE23.11.2016
CY23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
IE15.05.2017
LU15.05.2017
MT15.05.2017
CH31.05.2017
LI31.05.2017
Former [2019/31]HU15.05.2008
AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
IE15.05.2017
LU15.05.2017
MT15.05.2017
CH31.05.2017
LI31.05.2017
Former [2018/43]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
IE15.05.2017
LU15.05.2017
MT15.05.2017
CH31.05.2017
LI31.05.2017
Former [2018/23]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
IE15.05.2017
LU15.05.2017
CH31.05.2017
LI31.05.2017
Former [2018/17]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
LU15.05.2017
CH31.05.2017
LI31.05.2017
Former [2018/13]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
CH31.05.2017
LI31.05.2017
LU31.05.2017
Former [2018/06]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
MC23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
LU31.05.2017
Former [2017/52]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SI23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
LU31.05.2017
Former [2017/38]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SK23.11.2016
BG23.02.2017
NO23.02.2017
GR24.02.2017
PT23.03.2017
LU31.05.2017
Former [2017/37]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
IT23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SK23.11.2016
NO23.02.2017
GR24.02.2017
PT23.03.2017
LU31.05.2017
Former [2017/36]AT23.11.2016
BE23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
SK23.11.2016
NO23.02.2017
GR24.02.2017
PT23.03.2017
LU31.05.2017
Former [2017/35]AT23.11.2016
CZ23.11.2016
DK23.11.2016
EE23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
PL23.11.2016
RO23.11.2016
SE23.11.2016
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/33]AT23.11.2016
DK23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
PL23.11.2016
SE23.11.2016
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/26]AT23.11.2016
ES23.11.2016
FI23.11.2016
HR23.11.2016
LT23.11.2016
LV23.11.2016
NL23.11.2016
PL23.11.2016
SE23.11.2016
NO23.02.2017
GR24.02.2017
PT23.03.2017
Former [2017/12]LV23.11.2016
Documents cited:Search[X]WO2004038407  (BAYER HEALTHCARE AG [DE], et al) [X] 1-5,7,8,14,15* page 54, paragraph 1; claims 2, 4, 21 *;
 [XYI]WO2005103713  (GALAPAGOS GENOMICS NV [BE], et al) [X] 1-5,7,8,14,15 * page 1, paragraph 2 * * page 37; claims 17, 26-29 * [Y] 16-25 [I] 6,9-13;
 [X]  - TANAKA SHIGERU ET AL, "Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 6 APR 2007 LNKD- PUBMED:17284443, (20070406), vol. 282, no. 14, ISSN 0021-9258, pages 10506 - 10515, XP002634497 [X] 15 * page 10511, column r, paragraph 2 - paragraph 3; figure 7 *

DOI:   http://dx.doi.org/10.1074/JBC.M700911200
 [XY]  - IGNATOV ATANAS ET AL, "Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development.", JOURNAL OF NEUROSCIENCE, (20030201), vol. 23, no. 3, ISSN 0270-6474, pages 907 - 914, XP002634498 [X] 15 * abstract * * page 913, column l, paragraph last * [Y] 16-25
International search[X]US2005266502  (MERCHIERS PASCAL G [BE], et al);
 [Y]US2006247252  (TULLY TIMOTHY P [US], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.