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Extract from the Register of European Patents

EP About this file: EP2152664

EP2152664 - DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  10.07.2015
Database last updated on 11.04.2026
Most recent event   Tooltip13.10.2017Lapse of the patent in a contracting state
New state(s): BG, HU, TR		published on 15.11.2017  [2017/46]
Applicant(s)For all designated states
Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, NJ 08543 / US
[N/P]
Former [2014/36]For all designated states
Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, NJ 08543-4000 / US
Former [2010/07]For all designated states
Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton NJ 08543-4000 / US
Inventor(s)01 / PINTO, Donald J. P.
c/o Bristol-Myers Squibb Company
311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
02 / QUAN, Mimi L.
c/o Bristol-Myers Squibb Company
311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
03 / SMITH II, Leon M.
c/o Bristol-Myers Squibb Company
311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
04 / ORWAT, Michael J.
c/o Bristol-Myers Squibb Company
311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
05 / GILLIGAN, Paul J.
2629 Pennington Drive
Wilmington, DE 19810 / US
 [2014/36]
Former [2010/18]01 / PINTO, Donald J. P.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
02 / QUAN, Mimi L.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
03 / SMITH II, Leon M.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
04 / ORWAT, Michael J.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
05 / GILLIGAN, Paul J.
2629 Pennington Drive
Wilmington, DE 19810 / US
Former [2010/16]01 / PINTO, Donald J. P.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
02 / QUAN, Mimi L.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
03 / SMITH II, Leon M.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
04 / ORWAT, Michael J.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
05 / GILLIGAN, Paul J.
2629 Pennington Drive
Wilmington DE 19810 / US
Former [2010/07]01 / PINTO, Donald J. P.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
02 / QUAN, Mimi L.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
03 / SMITH II, Leon M.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
04 / ORWAT, Michael J.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
05 / GILLIGAN, Paul J.
c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road
Pennington, New Jersey 08534 / US
Representative(s)Beacham, Annabel Rose, et al
Dehns
St Bride's House
10 Salisbury Square
London EC4Y 8JD / GB
[2014/36]
Former [2010/18]Beacham, Annabel Rose, et al
Dehns St Bride's House 10 Salisbury Square London
EC4Y 8JD / GB
Former [2010/07]Beacham, Annabel Rose
Dehns St Bride's House 10 Salisbury Square London
EC4Y 8JD / GB
Application number, filing date08770664.411.06.2008
[2010/07]
WO2008US66506
Priority number, dateUS20070943791P13.06.2007         Original published format: US 943791 P
US20080049516P01.05.2008         Original published format: US 49516 P
[2014/36]
Former [2010/07]US20070943791P13.06.2007
US2008004951601.05.2008
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2008157162
Date:24.12.2008
Language:EN
[2008/52]
Type: A1 Application with search report 
No.:EP2152664
Date:17.02.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 24.12.2008 takes the place of the publication of the European patent application.
[2010/07]
Type: B1 Patent specification 
No.:EP2152664
Date:03.09.2014
Language:EN
[2014/36]
Search report(s)International search report - published on:EP24.12.2008
ClassificationIPC:C07C237/22, C07D403/12, C07D417/14, C07D231/56, C07D405/12, C07D471/04, C07D249/06, C07D409/12, C07D487/04, C07D257/04, C07D413/12, C07D498/04, C07D401/12, C07D417/12, A61K31/41
[2010/07]
CPC:
C07D257/04 (EP,US); A61P7/02 (EP); A61P9/00 (EP);
A61P9/04 (EP); A61P9/10 (EP); C07C237/22 (EP,US);
C07D231/56 (EP,US); C07D249/06 (EP,US); C07D401/12 (EP,US);
C07D403/12 (EP,US); C07D405/12 (EP,US); C07D409/12 (EP,US);
C07D413/12 (EP,US); C07D417/12 (EP,US); C07D417/14 (EP,US);
C07D471/04 (EP,US); C07D487/04 (EP,US); C07D498/04 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/07]
TitleGerman:DIPEPTIDANALOGA ALS KOAGULATIONSFAKTORHEMMER[2010/07]
English:DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS[2010/07]
French:ANALOGUES DIPEPTIDIQUES COMME INHIBITEURS DE FACTEURS DE COAGULATION[2010/07]
Entry into regional phase01.12.2009National basic fee paid 
01.12.2009Designation fee(s) paid 
01.12.2009Examination fee paid 
Examination procedure01.12.2009Amendment by applicant (claims and/or description)
01.12.2009Examination requested  [2010/07]
05.07.2010Despatch of a communication from the examining division (Time limit: M06)
18.11.2010Reply to a communication from the examining division
15.09.2011Despatch of a communication from the examining division (Time limit: M04)
20.01.2012Reply to a communication from the examining division
27.02.2014Communication of intention to grant the patent
26.06.2014Fee for grant paid
26.06.2014Fee for publishing/printing paid
26.06.2014Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  05.07.2010
Opposition(s)04.06.2015No opposition filed within time limit [2015/33]
Fees paidRenewal fee
11.06.2010Renewal fee patent year 03
13.06.2011Renewal fee patent year 04
24.05.2012Renewal fee patent year 05
10.06.2013Renewal fee patent year 06
12.06.2014Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU11.06.2008
AT03.09.2014
BE03.09.2014
BG03.09.2014
CY03.09.2014
CZ03.09.2014
DK03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
IT03.09.2014
LT03.09.2014
LV03.09.2014
MC03.09.2014
MT03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SI03.09.2014
SK03.09.2014
TR03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
[2017/39]
Former [2017/03]AT03.09.2014
BE03.09.2014
CY03.09.2014
CZ03.09.2014
DK03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
IT03.09.2014
LT03.09.2014
LV03.09.2014
MC03.09.2014
MT03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SI03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2016/33]AT03.09.2014
BE03.09.2014
CY03.09.2014
CZ03.09.2014
DK03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
IT03.09.2014
LT03.09.2014
LV03.09.2014
MC03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SI03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2016/09]AT03.09.2014
CY03.09.2014
CZ03.09.2014
DK03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
IT03.09.2014
LT03.09.2014
LV03.09.2014
MC03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SI03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2015/50]AT03.09.2014
CY03.09.2014
CZ03.09.2014
DK03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
IT03.09.2014
LT03.09.2014
LV03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SI03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2015/37]AT03.09.2014
CY03.09.2014
CZ03.09.2014
DK03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
IT03.09.2014
LT03.09.2014
LV03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2015/34]AT03.09.2014
CY03.09.2014
CZ03.09.2014
DK03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
LT03.09.2014
LV03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2015/24]AT03.09.2014
CY03.09.2014
CZ03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
LT03.09.2014
LV03.09.2014
NL03.09.2014
PL03.09.2014
RO03.09.2014
SE03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2015/23]AT03.09.2014
CY03.09.2014
CZ03.09.2014
EE03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
LT03.09.2014
LV03.09.2014
NL03.09.2014
RO03.09.2014
SE03.09.2014
SK03.09.2014
NO03.12.2014
GR04.12.2014
IS03.01.2015
PT05.01.2015
Former [2015/22]AT03.09.2014
CY03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
LT03.09.2014
LV03.09.2014
NL03.09.2014
RO03.09.2014
SE03.09.2014
NO03.12.2014
GR04.12.2014
PT05.01.2015
Former [2015/16]AT03.09.2014
CY03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
LT03.09.2014
LV03.09.2014
NL03.09.2014
SE03.09.2014
NO03.12.2014
GR04.12.2014
Former [2015/12]AT03.09.2014
CY03.09.2014
ES03.09.2014
FI03.09.2014
HR03.09.2014
LT03.09.2014
LV03.09.2014
SE03.09.2014
NO03.12.2014
GR04.12.2014
Former [2015/11]CY03.09.2014
ES03.09.2014
FI03.09.2014
LT03.09.2014
SE03.09.2014
NO03.12.2014
GR04.12.2014
Former [2015/10]ES03.09.2014
FI03.09.2014
LT03.09.2014
SE03.09.2014
NO03.12.2014
Former [2015/09]FI03.09.2014
LT03.09.2014
SE03.09.2014
Former [2015/08]LT03.09.2014
Cited inInternational search[A]   HOWARD N ET AL: "Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors", JOURNAL OF MEDICINAL CHEMISTRY, US AMERICAN CHEMICAL SOCIETY. WASHINGTON, vol. 49, no. 4, 20 January 2006 (2006-01-20), pages 1346 - 1355, XP002406118, ISSN: 0022-2623 [A] 7-16 * the whole document *

DOI:   http://dx.doi.org/10.1021/jm050850v
by applicant  WALSH, P. N., THROMB. HAEMOSTASIS, vol. 82, 1999, pages 234 - 242
   HOFFMAN, M., BLOOD REVIEWS, vol. 17, 2003, pages S1 - S5
   HOWARD ET AL., J. MED. CHEM., vol. 49, 2006, pages 1346 - 1355
   "Hawley's Condensed Chemical Dictionary", 1997, J. WILEY & SONS, INC.
   "Remington's Pharmaceutical Sciences", 1990, MACK PUBLISHING COMPANY
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.