EP2176228 - NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 16.12.2011 Database last updated on 20.07.2024 | Most recent event Tooltip | 16.12.2011 | Application deemed to be withdrawn | published on 18.01.2012 [2012/03] | Applicant(s) | For all designated states NeuroSearch A/S Strandvejen 60 2900 Hellerup / DK | [N/P] |
Former [2010/16] | For all designated states NeuroSearch A/S Pederstrupvej 93 2750 Ballerup / DK | Inventor(s) | 01 /
NARDI, Antonio c/o NeuroSearch A/S 93 Pederstrupvej DK-2750 Ballerup / DK | 02 /
CHRISTENSEN, Jeppe, Kejser c/o NeuroSearch A/S 93 Pederstrupvej DK-2750 Ballerup / DK | 03 /
JONES, David, Spencer c/o NeuroSearch A/S 93 Pederstrupvej DK-2750 Ballerup / DK | [2010/16] | Application number, filing date | 08774392.8 | 27.06.2008 | [2010/16] | WO2008EP58221 | Priority number, date | DK20070000988 | 04.07.2007 Original published format: DK 200700988 | US20070948322P | 06.07.2007 Original published format: US 948322 P | [2010/16] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2009003921 | Date: | 08.01.2009 | Language: | EN | [2009/02] | Type: | A1 Application with search report | No.: | EP2176228 | Date: | 21.04.2010 | Language: | EN | The application published by WIPO in one of the EPO official languages on 08.01.2009 takes the place of the publication of the European patent application. | [2010/16] | Search report(s) | International search report - published on: | EP | 08.01.2009 | Classification | IPC: | C07D231/12, C07D403/04, C07D403/06, A61K31/415, A61K31/4155 | [2010/16] | CPC: |
C07D231/12 (EP,US);
A61P1/00 (EP);
A61P1/02 (EP);
A61P1/04 (EP);
A61P1/08 (EP);
A61P1/10 (EP);
A61P1/12 (EP);
A61P11/00 (EP);
A61P11/02 (EP);
A61P13/00 (EP);
A61P13/10 (EP);
A61P13/12 (EP);
A61P15/00 (EP);
A61P15/10 (EP);
A61P17/14 (EP);
A61P21/00 (EP);
A61P21/02 (EP);
A61P25/00 (EP);
A61P25/02 (EP);
A61P25/04 (EP);
A61P25/06 (EP);
A61P25/08 (EP);
A61P25/16 (EP);
A61P25/18 (EP);
A61P25/20 (EP);
A61P25/22 (EP);
A61P25/24 (EP);
A61P25/28 (EP);
A61P27/00 (EP);
A61P27/02 (EP);
A61P27/16 (EP);
A61P29/00 (EP);
A61P3/10 (EP);
A61P35/00 (EP);
A61P37/06 (EP);
A61P43/00 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
A61P9/12 (EP);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2010/16] | Title | German: | ALS KALIUMKANALMODULATOREN GEEIGNETE NEUE PYRAZOLDERIVATE | [2010/16] | English: | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | [2010/16] | French: | NOUVEAUX DÉRIVÉS DE PYRAZOLE UTILES COMME MODULATEURS DES CANAUX POTASSIQUES | [2010/16] | Entry into regional phase | 04.02.2010 | National basic fee paid | 04.02.2010 | Designation fee(s) paid | 04.02.2010 | Examination fee paid | Examination procedure | 16.12.2009 | Amendment by applicant (claims and/or description) | 04.02.2010 | Examination requested [2010/16] | 01.06.2010 | Despatch of a communication from the examining division (Time limit: M06) | 29.11.2010 | Reply to a communication from the examining division | 21.03.2011 | Communication of intention to grant the patent | 02.08.2011 | Application deemed to be withdrawn, date of legal effect [2012/03] | 02.09.2011 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2012/03] | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 01.06.2010 | Fees paid | Renewal fee | 30.06.2010 | Renewal fee patent year 03 | Penalty fee | Additional fee for renewal fee | 30.06.2011 | 04   M06   Not yet paid |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [A]WO2006100212 (NEUROSEARCH AS [DK], et al) [A] 1-10,1-10,1-10 * the whole document * * the whole document * * the whole document *; | [A]JP2006316054 (TANABE SEIYAKU CO) [A] 1-10,1-10,1-10 * abstract * * abstract * * abstract * | [X] - BRATENKO M K ET AL, "4-Functionally-substituted 3-heterylpyrazoles: XVI. 3-(3-Arylpyrazol-4-yl)propyonic acids", RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, NAUKA/INTERPERIODICA, MO, (20060501), vol. 42, no. 5, ISSN 1608-3393, pages 701 - 702, XP019407467 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds IIIa-e * * compounds IIIa-e * * compounds IIIa-e * DOI: http://dx.doi.org/10.1134/S1070428006050095 | [X] - BRATENKO M K ET AL, "FUNCTIONALLY SUBSTITUTED 3-HETERYLPYRAZOLES: XI. 3-[3-ARYL(HETERYL)PYRAZOL-4-YL]PROPENOIC AND PROPANOIC ACIDS", RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, CONSULTANTS BUREAU, US, (20020101), vol. 38, no. 8, ISSN 1070-4280, pages 1171 - 1177, XP009025357 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds IIa-i * * compounds IIa-i * * compounds IIa-i * DOI: http://dx.doi.org/10.1023/A:1020905727368 | [X] - REDDY G J ET AL, "A Simple and Rapid Synthesis of 4H-4-OXO-1-Benzopyran-3-YL and 1.3-Diarylpyrazol-4-YL Propanoic Acids", HETEROCYCLIC COMMUNICATIONS, FREUND PUBLISHING HOUSE, TEL AVIV, (20060101), vol. 12, no. 6, ISSN 0793-0283, pages 423 - 426, XP009106702 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds 5a-h of table I * * compounds 5a-h of table I * * compounds 5a-h of table I * | [X] - BERNARD M ET AL, "Azole. Teil 17. Mitteilung: Beta-(4-Pyrazol)acryl-bzw.-propionsäure und ihre antiphlogistische Wirkung = Azoles. Part 17: Beta-(4-Pyrazole)acrylic and -propionic Acids and their Antiinflammatory Activity", PHARMAZIE, DIE, GOVI VERLAG, ESCHBORN, DE, (19860101), vol. 41, no. 8, ISSN 0031-7144, pages 560 - 562, XP001538580 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * table 1 * * table 1 * * table 1 * | [X] - GREGORY R BEBERNITZ ET AL, "The effect of 1,3-diaryl-[1H]-pyrazole-4-acetamides on glucose utilization in ob/ob mice", JOURNAL OF MEDICINAL CHEMISTRY, US AMERICAN CHEMICAL SOCIETY. WASHINGTON, (20010101), vol. 16, ISSN 0022-2623, pages 2601 - 2611, XP009106701 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compound 6g, page 2609 * * compound 6g, page 2609 * * compound 6g, page 2609 * DOI: http://dx.doi.org/10.1021/jm010032c | [X] - MARCINKOWSKI K. ET AL., "Azoles", JOURNAL FUER PRAKTISCHE CHEMIE, (1989), vol. 331, no. 4, pages 677 - 684, XP009106745 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds 1a-g and 3a-g * * compounds 1a-g and 3a-g * * compounds 1a-g and 3a-g * DOI: http://dx.doi.org/10.1002/prac.19893310420 | [X] - CHORNOUS VITALIY ET AL., "Microwave-assisted synthesis of 3-(4-pyrazolyl)propenoic acids", SYNTHETIC COMMUNICATION, (2004), vol. 34, no. 1, pages 79 - 83, XP009106839 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds 22-34 * * compounds 22-34 * * compounds 22-34 * DOI: http://dx.doi.org/10.1081/SCC-120027241 | by applicant | GB1373212 | - RUSSIAN JOURNAL OF ORQANIC CHEMISTRY, (2002), vol. 38, no. 8, pages 1171 - 1177 | - BRATENKO ET AL., RUSSIAN JOURNAL OF ORQANIC CHEMISTRY, (2006), vol. 42, no. 5, pages 701 - 702 | - REDDY ET AL., HETEROCYCLIC COMM., (2006), vol. 12, no. 6, pages 423 - 426 | - BERNARD ET AL., PHARMAZIE, (1986), vol. 41, no. 8, pages 560 - 562 | - BEBERNITZ ET AL., J. MED. CHEM., (2001), vol. 16, pages 2601 - 2611 | - BERNARD ET AL., JOURNAL FUR PRAKTISCHE CHEMIE, (1989), vol. 331, no. 4, pages 677 - 684 | - CHORNOUS ET AL., SYNTHETIC COMMUNICATIONS, (2004), vol. 34, no. 1, pages 79 - 83 | - Reminqton's Pharmaceutical Sciences, MAACK PUBLISHING CO. | - RATHELOT; PASCAL ET AL., EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, (2002), vol. 37, no. 8, pages 671 - 679 | - BERNARD M ET AL., PHARMAZIE, (1986), vol. 41, no. 8, pages 560 - 562 | - MAJETICH G ET AL., JOURNAL OF ORQANIC CHEMISTRY, (1986), vol. 51, no. 10, pages 1745 - 53 | - VALGEIRSSON ET AL., JOURNAL OF MEDICINAL CHEMISTRY, (2004), vol. 47, no. 27, pages 6948 - 6957 | - SYNTHETIC COMMUNICATIONS, (1995), vol. 25, no. 19, pages 3067 - 3074 | - GAZIT, JOURNAL OF MEDICIAL CHEMISTRY, (1989), vol. 32, pages 2344 - 2352 |