blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2176228

EP2176228 - NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  16.12.2011
Database last updated on 20.07.2024
Most recent event   Tooltip16.12.2011Application deemed to be withdrawnpublished on 18.01.2012  [2012/03]
Applicant(s)For all designated states
NeuroSearch A/S
Strandvejen 60
2900 Hellerup / DK
[N/P]
Former [2010/16]For all designated states
NeuroSearch A/S
Pederstrupvej 93
2750 Ballerup / DK
Inventor(s)01 / NARDI, Antonio
c/o NeuroSearch A/S 93 Pederstrupvej
DK-2750 Ballerup / DK
02 / CHRISTENSEN, Jeppe, Kejser
c/o NeuroSearch A/S 93 Pederstrupvej
DK-2750 Ballerup / DK
03 / JONES, David, Spencer
c/o NeuroSearch A/S 93 Pederstrupvej
DK-2750 Ballerup / DK
 [2010/16]
Application number, filing date08774392.827.06.2008
[2010/16]
WO2008EP58221
Priority number, dateDK2007000098804.07.2007         Original published format: DK 200700988
US20070948322P06.07.2007         Original published format: US 948322 P
[2010/16]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009003921
Date:08.01.2009
Language:EN
[2009/02]
Type: A1 Application with search report 
No.:EP2176228
Date:21.04.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 08.01.2009 takes the place of the publication of the European patent application.
[2010/16]
Search report(s)International search report - published on:EP08.01.2009
ClassificationIPC:C07D231/12, C07D403/04, C07D403/06, A61K31/415, A61K31/4155
[2010/16]
CPC:
C07D231/12 (EP,US); A61P1/00 (EP); A61P1/02 (EP);
A61P1/04 (EP); A61P1/08 (EP); A61P1/10 (EP);
A61P1/12 (EP); A61P11/00 (EP); A61P11/02 (EP);
A61P13/00 (EP); A61P13/10 (EP); A61P13/12 (EP);
A61P15/00 (EP); A61P15/10 (EP); A61P17/14 (EP);
A61P21/00 (EP); A61P21/02 (EP); A61P25/00 (EP);
A61P25/02 (EP); A61P25/04 (EP); A61P25/06 (EP);
A61P25/08 (EP); A61P25/16 (EP); A61P25/18 (EP);
A61P25/20 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P27/00 (EP); A61P27/02 (EP);
A61P27/16 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P35/00 (EP); A61P37/06 (EP); A61P43/00 (EP);
A61P9/00 (EP); A61P9/10 (EP); A61P9/12 (EP);
C07D403/06 (EP,US); C07D413/06 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/16]
TitleGerman:ALS KALIUMKANALMODULATOREN GEEIGNETE NEUE PYRAZOLDERIVATE[2010/16]
English:NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS[2010/16]
French:NOUVEAUX DÉRIVÉS DE PYRAZOLE UTILES COMME MODULATEURS DES CANAUX POTASSIQUES[2010/16]
Entry into regional phase04.02.2010National basic fee paid 
04.02.2010Designation fee(s) paid 
04.02.2010Examination fee paid 
Examination procedure16.12.2009Amendment by applicant (claims and/or description)
04.02.2010Examination requested  [2010/16]
01.06.2010Despatch of a communication from the examining division (Time limit: M06)
29.11.2010Reply to a communication from the examining division
21.03.2011Communication of intention to grant the patent
02.08.2011Application deemed to be withdrawn, date of legal effect  [2012/03]
02.09.2011Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2012/03]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  01.06.2010
Fees paidRenewal fee
30.06.2010Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
30.06.201104   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[A]WO2006100212  (NEUROSEARCH AS [DK], et al) [A] 1-10,1-10,1-10 * the whole document * * the whole document * * the whole document *;
 [A]JP2006316054  (TANABE SEIYAKU CO) [A] 1-10,1-10,1-10 * abstract * * abstract * * abstract *
 [X]  - BRATENKO M K ET AL, "4-Functionally-substituted 3-heterylpyrazoles: XVI. 3-(3-Arylpyrazol-4-yl)propyonic acids", RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, NAUKA/INTERPERIODICA, MO, (20060501), vol. 42, no. 5, ISSN 1608-3393, pages 701 - 702, XP019407467 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds IIIa-e * * compounds IIIa-e * * compounds IIIa-e *

DOI:   http://dx.doi.org/10.1134/S1070428006050095
 [X]  - BRATENKO M K ET AL, "FUNCTIONALLY SUBSTITUTED 3-HETERYLPYRAZOLES: XI. 3-[3-ARYL(HETERYL)PYRAZOL-4-YL]PROPENOIC AND PROPANOIC ACIDS", RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, CONSULTANTS BUREAU, US, (20020101), vol. 38, no. 8, ISSN 1070-4280, pages 1171 - 1177, XP009025357 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds IIa-i * * compounds IIa-i * * compounds IIa-i *

DOI:   http://dx.doi.org/10.1023/A:1020905727368
 [X]  - REDDY G J ET AL, "A Simple and Rapid Synthesis of 4H-4-OXO-1-Benzopyran-3-YL and 1.3-Diarylpyrazol-4-YL Propanoic Acids", HETEROCYCLIC COMMUNICATIONS, FREUND PUBLISHING HOUSE, TEL AVIV, (20060101), vol. 12, no. 6, ISSN 0793-0283, pages 423 - 426, XP009106702 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds 5a-h of table I * * compounds 5a-h of table I * * compounds 5a-h of table I *
 [X]  - BERNARD M ET AL, "Azole. Teil 17. Mitteilung: Beta-(4-Pyrazol)acryl-bzw.-propionsäure und ihre antiphlogistische Wirkung = Azoles. Part 17: Beta-(4-Pyrazole)acrylic and -propionic Acids and their Antiinflammatory Activity", PHARMAZIE, DIE, GOVI VERLAG, ESCHBORN, DE, (19860101), vol. 41, no. 8, ISSN 0031-7144, pages 560 - 562, XP001538580 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * table 1 * * table 1 * * table 1 *
 [X]  - GREGORY R BEBERNITZ ET AL, "The effect of 1,3-diaryl-[1H]-pyrazole-4-acetamides on glucose utilization in ob/ob mice", JOURNAL OF MEDICINAL CHEMISTRY, US AMERICAN CHEMICAL SOCIETY. WASHINGTON, (20010101), vol. 16, ISSN 0022-2623, pages 2601 - 2611, XP009106701 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compound 6g, page 2609 * * compound 6g, page 2609 * * compound 6g, page 2609 *

DOI:   http://dx.doi.org/10.1021/jm010032c
 [X]  - MARCINKOWSKI K. ET AL., "Azoles", JOURNAL FUER PRAKTISCHE CHEMIE, (1989), vol. 331, no. 4, pages 677 - 684, XP009106745 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds 1a-g and 3a-g * * compounds 1a-g and 3a-g * * compounds 1a-g and 3a-g *

DOI:   http://dx.doi.org/10.1002/prac.19893310420
 [X]  - CHORNOUS VITALIY ET AL., "Microwave-assisted synthesis of 3-(4-pyrazolyl)propenoic acids", SYNTHETIC COMMUNICATION, (2004), vol. 34, no. 1, pages 79 - 83, XP009106839 [X] 1,3-5,7,1,3-5,7,1,3-5,7 * compounds 22-34 * * compounds 22-34 * * compounds 22-34 *

DOI:   http://dx.doi.org/10.1081/SCC-120027241
by applicantGB1373212
    - RUSSIAN JOURNAL OF ORQANIC CHEMISTRY, (2002), vol. 38, no. 8, pages 1171 - 1177
    - BRATENKO ET AL., RUSSIAN JOURNAL OF ORQANIC CHEMISTRY, (2006), vol. 42, no. 5, pages 701 - 702
    - REDDY ET AL., HETEROCYCLIC COMM., (2006), vol. 12, no. 6, pages 423 - 426
    - BERNARD ET AL., PHARMAZIE, (1986), vol. 41, no. 8, pages 560 - 562
    - BEBERNITZ ET AL., J. MED. CHEM., (2001), vol. 16, pages 2601 - 2611
    - BERNARD ET AL., JOURNAL FUR PRAKTISCHE CHEMIE, (1989), vol. 331, no. 4, pages 677 - 684
    - CHORNOUS ET AL., SYNTHETIC COMMUNICATIONS, (2004), vol. 34, no. 1, pages 79 - 83
    - Reminqton's Pharmaceutical Sciences, MAACK PUBLISHING CO.
    - RATHELOT; PASCAL ET AL., EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, (2002), vol. 37, no. 8, pages 671 - 679
    - BERNARD M ET AL., PHARMAZIE, (1986), vol. 41, no. 8, pages 560 - 562
    - MAJETICH G ET AL., JOURNAL OF ORQANIC CHEMISTRY, (1986), vol. 51, no. 10, pages 1745 - 53
    - VALGEIRSSON ET AL., JOURNAL OF MEDICINAL CHEMISTRY, (2004), vol. 47, no. 27, pages 6948 - 6957
    - SYNTHETIC COMMUNICATIONS, (1995), vol. 25, no. 19, pages 3067 - 3074
    - GAZIT, JOURNAL OF MEDICIAL CHEMISTRY, (1989), vol. 32, pages 2344 - 2352
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.