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Extract from the Register of European Patents

EP About this file: EP2180787

EP2180787 - NITRO OLEIC ACID MODULATION OF TYPE II DIABETES [Right-click to bookmark this link]
Former [2010/18]NITRATED-FATTY ACIDS MODULATION OF TYPE II DIABETES
[2013/08]
StatusNo opposition filed within time limit
Status updated on  05.09.2014
Database last updated on 07.06.2024
Most recent event   Tooltip15.07.2016Lapse of the patent in a contracting state
New state(s): TR		published on 17.08.2016  [2016/33]
Applicant(s)For all designated states
University of Pittsburgh - Of the Commonwealth System of Higher Education
200 Gardner Steel Conference Center
Thackeray & O'Hara Streets
Pittsburgh, PA 15260 / US
[N/P]
Former [2010/18]For all designated states
University of Pittsburgh - Of the Commonwealth System of Higher Education
200 Gardner Steel Conference Center Thackeray & O'Hara Streets
Pittsburgh, PA 15260 / US
Inventor(s)01 / FREEMAN, Bruce, A.
5801 Wilkins Avenue
Pittsburgh, PA 15217 / US
 [2010/18]
Representative(s)Plougmann Vingtoft a/s
Strandvejen 70
2900 Hellerup / DK
[N/P]
Former [2013/44]Plougmann & Vingtoft A/S
Rued Langgaards Vej 8
2300 Copenhagen S / DK
Former [2010/18]Plougmann & Vingtoft A/S
Sundkrogsgade 9 P.O. Box 831
2100 Copenhagen Ø / DK
Application number, filing date08780348.201.08.2008
[2010/18]
WO2008US09274
Priority number, dateUS20070953360P01.08.2007         Original published format: US 953360 P
[2010/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009017802
Date:05.02.2009
Language:EN
[2009/06]
Type: A1 Application with search report 
No.:EP2180787
Date:05.05.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 05.02.2009 takes the place of the publication of the European patent application.
[2010/18]
Type: B1 Patent specification 
No.:EP2180787
Date:30.10.2013
Language:EN
[2013/44]
Search report(s)International search report - published on:US05.02.2009
(Supplementary) European search report - dispatched on:EP30.07.2010
ClassificationIPC:A01N37/00, A61K31/20, A61P3/10
[2010/34]
CPC:
A61K31/201 (EP,US); A61K31/20 (EP,US); A61K45/06 (EP,US);
A61P3/10 (EP)
C-Set:
A61K31/201, A61K2300/00 (EP,US)
Former IPC [2010/18]A01N37/00, A61K31/20
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/18]
TitleGerman:MODULATION DES TYP-II-DIABETES DURCH NITRIERTE ÖLSÄURE[2013/20]
English:NITRO OLEIC ACID MODULATION OF TYPE II DIABETES[2013/08]
French:ACIDE OLÉIQUE NITRÉ POUR LE TRAITEMENT DU DIABÈTE DE TYPE II[2013/20]
Former [2010/18]MODULATION DES TYP-II-DIABETES DURCH NITRIERTE FETTSÄUREN
Former [2010/18]NITRATED-FATTY ACIDS MODULATION OF TYPE II DIABETES
Former [2010/18]ACIDES GRAS NITRÉS POUR LE TRAITEMENT DU DIABÈTE
Entry into regional phase23.02.2010National basic fee paid 
23.02.2010Search fee paid 
23.02.2010Designation fee(s) paid 
23.02.2010Examination fee paid 
Examination procedure23.02.2010Examination requested  [2010/18]
28.02.2011Amendment by applicant (claims and/or description)
26.07.2011Despatch of a communication from the examining division (Time limit: M04)
05.12.2011Reply to a communication from the examining division
16.01.2013Cancellation of oral proceeding that was planned for 21.01.2013
21.01.2013Date of oral proceedings (cancelled)
28.01.2013Despatch of a communication from the examining division (Time limit: M02)
04.04.2013Reply to a communication from the examining division
06.05.2013Communication of intention to grant the patent
16.09.2013Fee for grant paid
16.09.2013Fee for publishing/printing paid
Divisional application(s)EP13179211.1  / EP2679224
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.07.2011
Opposition(s)31.07.2014No opposition filed within time limit [2014/41]
Fees paidRenewal fee
25.08.2010Renewal fee patent year 03
24.08.2011Renewal fee patent year 04
10.08.2012Renewal fee patent year 05
19.08.2013Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU01.08.2008
AT30.10.2013
BE30.10.2013
BG30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
IT30.10.2013
LT30.10.2013
LV30.10.2013
MC30.10.2013
MT30.10.2013
PL30.10.2013
RO30.10.2013
SI30.10.2013
SK30.10.2013
TR30.10.2013
NO30.01.2014
GR31.01.2014
IS28.02.2014
PT28.02.2014
[2016/33]
Former [2016/32]HU01.08.2008
AT30.10.2013
BE30.10.2013
BG30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
IT30.10.2013
LT30.10.2013
LV30.10.2013
MC30.10.2013
MT30.10.2013
PL30.10.2013
RO30.10.2013
SI30.10.2013
SK30.10.2013
NO30.01.2014
GR31.01.2014
IS28.02.2014
PT28.02.2014
Former [2016/28]AT30.10.2013
BE30.10.2013
BG30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
IT30.10.2013
LT30.10.2013
LV30.10.2013
MC30.10.2013
MT30.10.2013
PL30.10.2013
RO30.10.2013
SI30.10.2013
SK30.10.2013
NO30.01.2014
GR31.01.2014
IS28.02.2014
PT28.02.2014
Former [2016/25]AT30.10.2013
BE30.10.2013
BG30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
IT30.10.2013
LT30.10.2013
LV30.10.2013
MC30.10.2013
PL30.10.2013
RO30.10.2013
SI30.10.2013
SK30.10.2013
NO30.01.2014
IS28.02.2014
PT28.02.2014
Former [2015/18]AT30.10.2013
BE30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
IT30.10.2013
LT30.10.2013
LV30.10.2013
MC30.10.2013
PL30.10.2013
RO30.10.2013
SI30.10.2013
SK30.10.2013
NO30.01.2014
IS28.02.2014
PT28.02.2014
Former [2015/14]AT30.10.2013
BE30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
IT30.10.2013
LT30.10.2013
LV30.10.2013
PL30.10.2013
RO30.10.2013
SI30.10.2013
SK30.10.2013
NO30.01.2014
IS28.02.2014
PT28.02.2014
Former [2014/38]AT30.10.2013
BE30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
IT30.10.2013
LT30.10.2013
LV30.10.2013
PL30.10.2013
RO30.10.2013
SK30.10.2013
NO30.01.2014
IS28.02.2014
PT28.02.2014
Former [2014/37]AT30.10.2013
BE30.10.2013
CY30.10.2013
CZ30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
LT30.10.2013
LV30.10.2013
PL30.10.2013
RO30.10.2013
SK30.10.2013
NO30.01.2014
IS28.02.2014
PT28.02.2014
Former [2014/36]AT30.10.2013
BE30.10.2013
CY30.10.2013
EE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
LT30.10.2013
LV30.10.2013
NO30.01.2014
IS28.02.2014
PT28.02.2014
Former [2014/28]AT30.10.2013
BE30.10.2013
CY30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
LT30.10.2013
LV30.10.2013
NO30.01.2014
IS28.02.2014
PT28.02.2014
Former [2014/26]AT30.10.2013
BE30.10.2013
CY30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
LT30.10.2013
LV30.10.2013
NO30.01.2014
IS28.02.2014
Former [2014/25]AT30.10.2013
BE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
LT30.10.2013
LV30.10.2013
NO30.01.2014
IS28.02.2014
Former [2014/24]AT30.10.2013
BE30.10.2013
ES30.10.2013
FI30.10.2013
HR30.10.2013
LT30.10.2013
NO30.01.2014
IS28.02.2014
Former [2014/23]BE30.10.2013
FI30.10.2013
HR30.10.2013
LT30.10.2013
NO30.01.2014
IS28.02.2014
Former [2014/22]FI30.10.2013
LT30.10.2013
NO30.01.2014
Former [2014/20]LT30.10.2013
NO30.01.2014
Documents cited:Search[I]WO2006086727  (ENTELOS INC [US], et al) [I] 1-7 * claims 1,2,21 *
 [I]  - BAKER PAUL R S ET AL, "Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 23 DEC 2005 LNKD- PUBMED:16227625, (20051223), vol. 280, no. 51, ISSN 0021-9258, pages 42464 - 42475, XP002592314 [I] 1-7 * page 42465, column 1, paragraph 2 * * page 42469, column 1, paragraph 1 - page 42470, column 2, paragraph 1 * * page 42473, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1074/JBC.M504212200
 [I]  - MARX NIKOLAUS ET AL, "Peroxisome proliferator-activated receptors and atherogenesis - Regulators of gene expression in vascular cells", CIRCULATION RESEARCH, (20040514), vol. 94, no. 9, ISSN 0009-7330, pages 1168 - 1178, XP002592315 [I] 1-7 * abstract *
International search[Y]US6187747  (SINGH AMARJIT [IN], et al);
 [Y]US2006100278  (COOPER GARTH J S [NZ], et al)
 [Y]  - MITSCHKE ET AL., "9- and 10-Nitro-oleic acid do not interfere with the GC-MS quantitative determination of nitrite and nitrate in biological fluids when measured as their pentafluorobenzyl derivatives", JOURNAL OF CHROMATOGRAPHY, (200705), vol. 85, no. 1, pages 287 - 291, XP008130022
 [Y]  - RYAN ET AL., "Diabetes and the Mediterranean diet: a beneficial effect of oleic acid on insulin sensitivity, adipocyte glucose transport and endothelium-dependent vasoreactivity?", Q.J. MED., (2000), vol. 93, pages 85 - 91, XP008130023

DOI:   http://dx.doi.org/10.1093/qjmed/93.2.85
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