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EP About this file: EP2188307

EP2188307 - GLYCOSAMINOGLYCAN-ANTAGONISING MCP-1 MUTANTS AND METHODS OF USING SAME [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  01.08.2014
Database last updated on 03.09.2024
Most recent event   Tooltip01.08.2014Application deemed to be withdrawnpublished on 03.09.2014  [2014/36]
Applicant(s)For all designated states
ProtAffin Biotechnologie AG
Impulszentrum Graz-West
Reininghausstrasse 13a
8020 Graz / AT
[N/P]
Former [2010/21]For all designated states
Protaffin Biotechnologie AG
Impulszentrum Graz-West Reininghausstrasse 13a
8020 Graz / AT
Inventor(s)01 / KUNGL, Andreas
Strasserhofweg 77a
A-8045 Graz / AT
02 / PICCININI, Anna Maria
7 Spencer News Greyhound Road
London W6 9PB / GB
03 / WEBER, Christian
Kaiser-Friedrich-Allee 59
52074 Aachen / DE
 [2010/31]
Former [2010/21]01 / KUNGL, Andreas
Strasserhofweg 77a
A-8045 Graz / AT
02 / PICCININI, Anna Maria
803 Fulham Road
London SW6 5HE / GB
03 / WEBER, Christian
Kaiser-Friedrich-Allee 59
52074 Aachen / DE
Representative(s)Redl, Gerda
REDL Life Science Patent Attorneys
Donau-City-Strasse 11
1220 Wien / AT
[N/P]
Former [2010/21]Redl, Gerda
REDL Life Science Patent Attorneys Tech Gate Vienna Donau-City-Strasse 1
1220 Vienna / AT
Application number, filing date08785241.431.07.2008
[2010/21]
WO2008EP06298
Priority number, dateUS20070953140P31.07.2007         Original published format: US 953140 P
EP2007045016627.09.2007         Original published format: EP 07450166
[2010/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009015884
Date:05.02.2009
Language:EN
[2009/06]
Type: A1 Application with search report 
No.:EP2188307
Date:26.05.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 05.02.2009 takes the place of the publication of the European patent application.
[2010/21]
Search report(s)International search report - published on:EP05.02.2009
ClassificationIPC:C07K14/52
[2010/21]
CPC:
C07K14/523 (EP,US); A61P1/04 (EP); A61P29/00 (EP);
A61P31/14 (EP); A61P43/00 (EP); A61P9/04 (EP);
A61P9/10 (EP); G01N33/5047 (US); A61K38/00 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/21]
Extension statesAL16.02.2010
BA16.02.2010
MK16.02.2010
RS16.02.2010
TitleGerman:GLYKOSAMINOGLYKANANTAGONISIERENDE MCP-1-MUTANTEN UND VERFAHREN ZU DEREN ANWENDUNG[2010/21]
English:GLYCOSAMINOGLYCAN-ANTAGONISING MCP-1 MUTANTS AND METHODS OF USING SAME[2010/21]
French:MUTANTS MCP-1 ANTAGONISANT LE GLYCOSAMINOGLYCAN ET LEURS PROCÉDÉS D'UTILISATION[2010/21]
Entry into regional phase16.02.2010National basic fee paid 
16.02.2010Designation fee(s) paid 
16.02.2010Examination fee paid 
Examination procedure02.06.2009Request for preliminary examination filed
International Preliminary Examining Authority: EP
16.02.2010Examination requested  [2010/21]
26.07.2010Despatch of a communication from the examining division (Time limit: M04)
20.10.2010Reply to a communication from the examining division
10.02.2012Despatch of a communication from the examining division (Time limit: M04)
19.06.2012Reply to a communication from the examining division
25.10.2013Despatch of a communication from the examining division (Time limit: M04)
05.03.2014Application deemed to be withdrawn, date of legal effect  [2014/36]
28.03.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2014/36]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.07.2010
Fees paidRenewal fee
27.07.2010Renewal fee patent year 03
25.07.2011Renewal fee patent year 04
23.07.2012Renewal fee patent year 05
22.07.2013Renewal fee patent year 06
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Cited inInternational search[Y]WO2005054285  (KUNGL ANDREAS J [AT]) [Y] 19,20 * page 3 - page 4; claims 2,3,5; table 1 * * page 7 - page 8 * * page 14, paragraph 2 *;
 [X]US2003162737  (EGASHIRA KENSUKE [JP], et al) [X] 1-5,10,11,13,15-20 * the whole document *;
 [XDY]  - JARNAGIN KURT ET AL, "Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, (19991207), vol. 38, no. 49, ISSN 0006-2960, pages 16167 - 16177, XP002336958 [XD] 1-11,13,15-17 * abstract * [Y] 19,20

DOI:   http://dx.doi.org/10.1021/bi9912239
 [X]  - STEITZ S A ET AL, "Mapping of MCP-1 functional domains by peptide analysis and site-directed mutagenesis", FEBS LETTERS, ELSEVIER, AMSTERDAM, NL, (19980703), vol. 430, no. 3, ISSN 0014-5793, pages 158 - 164, XP004258051 [X] 1,5,8,11,13,15,16 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0014-5793(98)00637-1
 [X]  - PAAVOLA CHAD D ET AL, "Monomeric monocyte chemoattractant protein-1 (MCP-1) binds and activates the MCP-1 receptor CCR2B", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, (19981211), vol. 273, no. 50, ISSN 0021-9258, pages 33157 - 33165, XP002283331 [X] 1,4,8,11,13,15,16 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.273.50.33157
 [A]  - POTZINGER H ET AL, "Developing chemokine mutants with improved proteoglycan affinity and knocked-out GPCR activity as anti-inflammatory recombinant drugs.", BIOCHEMICAL SOCIETY TRANSACTIONS JUN 2006, (200606), vol. 34, no. Pt 3, ISSN 0300-5127, pages 435 - 437, XP002462147

DOI:   http://dx.doi.org/10.1042/BST0340435
 [A]  - GESSLBAUER BERND ET AL, "Glycomic approaches toward drug development: therapeutically exploring the glycosaminoglycanome.", CURRENT OPINION IN MOLECULAR THERAPEUTICS DEC 2006, (200612), vol. 8, no. 6, ISSN 1464-8431, pages 521 - 528, XP002462149
 [DA]  - LAU ELAINE K ET AL, "Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1 - Implications for structure and function in vivo", JOURNAL OF BIOLOGICAL CHEMISTRY, (20040521), vol. 279, no. 21, ISSN 0021-9258, pages 22294 - 22305, XP002462150

DOI:   http://dx.doi.org/10.1074/jbc.M311224200
 [DA]  - HEMMERICH STEFAN ET AL, "Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, (19991005), vol. 38, no. 40, ISSN 0006-2960, pages 13013 - 13025, XP002198634

DOI:   http://dx.doi.org/10.1021/bi991029m
 [PA]  - PROTAFFIN BIOTECHNOLOGIE AG, "CellJammerTM discovery technology", (20070907), URL: http://www.protaffin.com/images/content/pdfs/070907_protaffin_technology_profile.pdf?sid=05laac50gtpn2i073rg8k3mnk6, (20071204), XP002462148
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.