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Extract from the Register of European Patents

EP About this file: EP2183268

EP2183268 - METHODS FOR PURIFICATION OF ALPHA-1-ANTITRYPSIN AND APOLIPOPROTEIN A-I [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.08.2013
Database last updated on 13.09.2024
Most recent event   Tooltip17.07.2015Lapse of the patent in a contracting state
New state(s): HU		published on 19.08.2015  [2015/34]
Applicant(s)For all designated states
CSL Behring GmbH
Emil-von-Behring-Strasse 76
35041 Marburg / DE
[2010/19]
Inventor(s)01 / BRINKMAN, Nathan
429 N. Mulberry Street
St. Herscher, IL 60941 / US
02 / BIGLER, Douglas
456 S. Yates Avenue
Kankakee, IL 60901 / US
03 / BOLLI, Reinhard
Bellevuestrasse 14
3073 Gümligen / CH
04 / FOERTSCH, Vreni
Birkenweg 8
CH-4652 Winznau / CH
 [2010/40]
Former [2010/19]01 / BRINKMAN, Nathan
429 N. Mulberry Street
St. Herscher, IL 60941 / US
02 / BIGLER, Douglas
456 S. Yates Avenue
Kankakee, IL 60901 / US
03 / BOLLI, Reinhard
Niesenstr. 7
CH-3076 Worb / CH
04 / FOERTSCH, Vreni
Birkenweg 8
CH-4652 Winznau / CH
Representative(s)Hallybone, Huw George
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2012/41]Hallybone, Huw George
Carpmaels & Ransford One Southampton Row London
WC1B 5HA / GB
Former [2010/19]Hallybone, Huw George
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date08795338.615.08.2008
[2010/19]
WO2008US09745
Priority number, dateUS20070935527P17.08.2007         Original published format: US 935527 P
[2010/19]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2009025754
Date:26.02.2009
Language:EN
[2009/09]
Type: A2 Application without search report 
No.:EP2183268
Date:12.05.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 26.02.2009 takes the place of the publication of the European patent application.
[2010/19]
Type: B1 Patent specification 
No.:EP2183268
Date:10.10.2012
Language:EN
[2012/41]
Search report(s)International search report - published on:EP30.04.2009
ClassificationIPC:C07K1/14, C07K1/16, C07K1/30, C07K1/36, C07K14/775, C07K14/81
[2010/19]
CPC:
C07K14/775 (EP,US); C07K1/36 (US); C07K14/8125 (EP,US)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/19]
TitleGerman:VERFAHREN ZUR AUFREINIGUNG VON ALPHA-1-ANTITRYPSIN UND APOLIPOPROTEIN A-I[2010/19]
English:METHODS FOR PURIFICATION OF ALPHA-1-ANTITRYPSIN AND APOLIPOPROTEIN A-I[2010/19]
French:PROCÉDÉS DE PURIFICATION D'ALPHA-1-ANTITRYPSINE ET D'APOLIPOPROTÉINE A-I[2010/19]
Entry into regional phase17.02.2010National basic fee paid 
17.02.2010Designation fee(s) paid 
17.02.2010Examination fee paid 
Examination procedure17.02.2010Amendment by applicant (claims and/or description)
17.02.2010Examination requested  [2010/19]
15.06.2010Despatch of a communication from the examining division (Time limit: M06)
23.12.2010Reply to a communication from the examining division
18.02.2011Despatch of a communication from the examining division (Time limit: M06)
26.08.2011Reply to a communication from the examining division
17.04.2012Communication of intention to grant the patent
24.08.2012Fee for grant paid
24.08.2012Fee for publishing/printing paid
Divisional application(s)EP12172445.4  / EP2520583
EP12172446.2  / EP2522674
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  15.06.2010
Opposition(s)11.07.2013No opposition filed within time limit [2013/38]
Fees paidRenewal fee
11.08.2010Renewal fee patent year 03
11.08.2011Renewal fee patent year 04
10.08.2012Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU15.08.2008
CY10.10.2012
CZ10.10.2012
EE10.10.2012
FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
MC10.10.2012
MT10.10.2012
RO10.10.2012
SI10.10.2012
SK10.10.2012
BG10.01.2013
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
[2015/34]
Former [2015/32]CY10.10.2012
CZ10.10.2012
EE10.10.2012
FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
MC10.10.2012
MT10.10.2012
RO10.10.2012
SI10.10.2012
SK10.10.2012
BG10.01.2013
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
Former [2014/20]CY10.10.2012
CZ10.10.2012
EE10.10.2012
FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
MC10.10.2012
RO10.10.2012
SI10.10.2012
SK10.10.2012
BG10.01.2013
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
Former [2013/52]CY10.10.2012
CZ10.10.2012
EE10.10.2012
FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
RO10.10.2012
SI10.10.2012
SK10.10.2012
BG10.01.2013
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
Former [2013/37]CZ10.10.2012
EE10.10.2012
FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
RO10.10.2012
SI10.10.2012
SK10.10.2012
BG10.01.2013
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
Former [2013/35]CZ10.10.2012
EE10.10.2012
FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
SI10.10.2012
SK10.10.2012
BG10.01.2013
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
Former [2013/34]FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
SI10.10.2012
BG10.01.2013
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
Former [2013/28]FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
SI10.10.2012
NO10.01.2013
GR11.01.2013
IS10.02.2013
PT11.02.2013
Former [2013/24]FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
SI10.10.2012
NO10.01.2013
GR11.01.2013
IS10.02.2013
Former [2013/23]FI10.10.2012
HR10.10.2012
LT10.10.2012
LV10.10.2012
SI10.10.2012
NO10.01.2013
IS10.02.2013
Former [2013/22]FI10.10.2012
LT10.10.2012
SI10.10.2012
NO10.01.2013
IS10.02.2013
Former [2013/20]LT10.10.2012
SI10.10.2012
NO10.01.2013
Former [2013/11]SI10.10.2012
Cited inInternational search[XY]WO0017227  (AMERICAN NAT RED CROSS [US]) [X] 1-15,19-25 * abstract * * page 16, line 8 - line 22 * [Y] 16-18;
 [Y]US2004124143  (KEE SCOTT M [US], et al) [Y] 14-18 * abstract *;
 [XY]WO2006023831  (PROMETIC BIOSCIENCES LTD [GB], et al) [X] 1-13,19-25 * example 1; claims 1,2,6,10; table 2 * [Y] 14-18;
 [A]WO2007062270  (PROTEOMTECH INC [US], et al) [A] 18-21 * paragraphs [0033] , [0113]; claim 30 *;
 [XY]WO2007063129  (NOVOZYMES AS [DK], et al) [X] 1-13,19-25 * page 65, line 1 - page 66, line 30; example 1 * [Y] 14-18;
 [DA]  - PEITSCH M C ET AL, "A PURIFICATION METHOD FOR APOLIPOPROTEIN A-I AND A-II", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC. NEW YORK, (19890101), vol. 178, no. 2, ISSN 0003-2697, pages 301 - 305, XP009023396 [DA] 1-25 * abstract *

DOI:   http://dx.doi.org/10.1016/0003-2697(89)90642-8
 [A]  - CHEN S X ET AL, "Chromatographic purification of human alpha1 proteinase inhibitor from dissolved Cohn fraction IV-1 paste", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, (19980327), vol. 800, no. 2, ISSN 0021-9673, pages 207 - 218, XP004113596 [A] 1-25 * abstract *

DOI:   http://dx.doi.org/10.1016/S0021-9673(97)01119-9
 [DA]  - COHN E J ET AL, "A system for the separation of the components of human blood: Quantitative procedures for the separation of the protein components of human plasma", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 1950, (1950), vol. 72, no. 1, ISSN 0002-7863, pages 465 - 474, XP002499900 [DA] 1-25 * tables III-V *

DOI:   http://dx.doi.org/10.1021/ja01157a122
 [Y]  - GLASER C B ET AL, "The isolation of alpha-1-protease inhibitor by a unique procedure designed for industrial application", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC. NEW YORK, vol. 124, no. 2, ISSN 0003-2697, (19820801), pages 364 - 371, (19820801), XP024825556 [Y] 14-18 * abstract *

DOI:   http://dx.doi.org/10.1016/0003-2697(82)90053-7
 [Y]  - AGNESE S T ET AL, "Evaluation of four reagents for delipidation of serum", CLINICAL BIOCHEMISTRY, ELSEVIER INC, US, CA, vol. 16, no. 2, ISSN 0009-9120, (19830401), pages 98 - 100, (19830401), XP023599939 [Y] 14-18 * abstract *

DOI:   http://dx.doi.org/10.1016/S0009-9120(83)90676-8
 [A]  - VALLANCE D T ET AL, "Precipitation procedures used to isolate high density lipoprotein with particular reference to effects on apo A-I-only particles and lipoprotein(a)", CLINICA CHIMICA ACTA, ELSEVIER BV, AMSTERDAM, NL, vol. 229, no. 1-2, ISSN 0009-8981, (19940901), pages 77 - 85, (19940901), XP025201141 [A] 14-18 * abstract *

DOI:   http://dx.doi.org/10.1016/0009-8981(94)90230-5
 [A]  - FETZ KATHRIN ET AL, "Purification and partial characterization of feline alpha1-proteinase inhibitor (falpha1-PI) and the development and validation of a radioimmunoassay for the measurement of falpha1-PI in serum.", BIOCHIMIE (PARIS), (200401), vol. 86, no. 1, ISSN 0300-9084, pages 67 - 75, XP002514306 [A] 18-21 * abstract *

DOI:   http://dx.doi.org/10.1016/j.biochi.2003.10.005
 [A]  - OLAH S ET AL, "Hydrophobic interaction chromatography of human serum alpha1-antitrypsin and alpha1-acid glycoprotein", JOURNAL OF CHROMATOGRAPHY B : BIOMEDICAL APPLICATIONS, ELSEVIER SCIENCE PUBLISHERS, NL, (20000707), vol. 744, no. 1, ISSN 0378-4347, pages 73 - 79, XP004222468 [A] 18-21 * abstract *

DOI:   http://dx.doi.org/10.1016/S0378-4347(00)00232-2
 [A]  - RAYNES J G ET AL, "Purification of serum amyloid a and other high density apolipoproteins by hydrophobic interaction chromatography", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC. NEW YORK, vol. 173, no. 1, ISSN 0003-2697, (19880815), pages 116 - 124, (19880815), XP024829904 [A] 18-21 * abstract *

DOI:   http://dx.doi.org/10.1016/0003-2697(88)90168-6
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