EP2183249 - 8-Azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists [Right-click to bookmark this link] | |||
Former [2010/19] | 8-AZABICYCLOÝ3.2.1 ỎCTYL-2-HYDROXYBENZAMIDE COMPOUNDS AS MU OPIOID RECEPTOR ANTAGONISTS | ||
[2013/35] | Status | No opposition filed within time limit Status updated on 02.01.2015 Database last updated on 03.09.2024 | Most recent event Tooltip | 15.07.2016 | Lapse of the patent in a contracting state New state(s): TR | published on 17.08.2016 [2016/33] | Applicant(s) | For all designated states Theravance Biopharma R&D IP, LLC 901 Gateway Boulevard South San Francisco, CA 94080 / US | [2014/43] |
Former [2010/19] | For all designated states Theravance, Inc. 901 Gateway Boulevard South San Francisco, CA 94080 / US | Inventor(s) | 01 /
SAITO, Daisuke Roland 1515 Broadway Avenue Apt 1 Burlingame, California 94010 / US | 02 /
LONG, Daniel D. 4358 23rd Street San Francisco, California 94114 / US | 03 /
VAN DYKE, Priscilla 550 Fell Street 5 San Francisco, California 94102 / US | 04 /
CHURCH, Timothy J. 3913 Pasadena Drive San Mateo, California 94403 / US | 05 /
JIANG, Lan 788 Santa Maria Lane Foster City, California 94404 / US | 06 /
FRIEMAN, Bryan 5220 Fiore Terrace Apt 301 San Diego, California 92122 / US | [2014/09] |
Former [2010/19] | 01 /
SAITO, Daisuke Roland 1515 Broadway Avenue Apt 1 Burlingame, California 94010 / US | ||
02 /
LONG, Daniel D. 4358 23rd Street San Francisco, California 94114 / US | |||
03 /
VAN DYKE, Priscilla 550 Fell Street 5 San Francisco, California 94102 / US | |||
04 /
CHURCH, Timothy J. 3913 Pasadena Drive San Mateo, California 94403 / US | |||
05 /
JIANG, Lan 788 Santa Maria Lane Foster City, California 94404 / US | |||
06 /
FRIEMAN, Bryan 5220 Fiore Terrace Apt 301 San Diego, California 92122 / US | Representative(s) | Scott, Susan Margaret, et al Abel & Imray 20 Red Lion Street London WC1R 4PQ / GB | [2014/09] |
Former [2010/19] | Scott, Susan Margaret, et al Abel & Imray 20 Red Lion Street London WC1R 4PQ / GB | Application number, filing date | 08795602.5 | 26.08.2008 | [2010/19] | WO2008US10100 | Priority number, date | US20070966364P | 27.08.2007 Original published format: US 966364 P | US20080051065 | 07.05.2008 Original published format: US 51065 | [2010/19] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2009029256 | Date: | 05.03.2009 | Language: | EN | [2009/10] | Type: | A1 Application with search report | No.: | EP2183249 | Date: | 12.05.2010 | Language: | EN | The application published by WIPO in one of the EPO official languages on 05.03.2009 takes the place of the publication of the European patent application. | [2010/19] | Type: | B1 Patent specification | No.: | EP2183249 | Date: | 26.02.2014 | Language: | EN | [2014/09] | Search report(s) | International search report - published on: | EP | 05.03.2009 | Classification | IPC: | C07D451/02, A61K31/46, A61P1/04, A61P1/08 | [2010/19] | CPC: |
C07D471/08 (EP,US);
A61K31/46 (EP,US);
A61K31/485 (EP,US);
A61P1/00 (EP);
A61P1/04 (EP);
A61P1/06 (EP);
A61P1/08 (EP);
A61P1/10 (EP);
A61P25/04 (EP);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2010/19] | Title | German: | 8-Azabicyclo[3.2.1]octyl-2-hydroxybenzamid-Verbindungen zur Verwendung als mü-Opioidrezeptor-Antagonisten | [2013/35] | English: | 8-Azabicyclo[3.2.1]octyl-2-hydroxybenzamide compounds as mu opioid receptor antagonists | [2013/35] | French: | Composés de 8-azabicyclo[3.2.1]octyl-2-hydroxybenzamide utilisés en tant qu'antagonistes du récepteur opioide mu | [2013/35] |
Former [2010/19] | 8-AZABICYCLO[3.2.1]OKTYL-2-HYDROXYBENZAMID-VERBINDUNGEN ALS MU-OPIOID-REZEPTORANTAGONISTEN | ||
Former [2010/19] | 8-AZABICYCLOÝ3.2.1 ỎCTYL-2-HYDROXYBENZAMIDE COMPOUNDS AS MU OPIOID RECEPTOR ANTAGONISTS | ||
Former [2010/19] | COMPOSES DE 8-AZABICYCLOÝ3.2.1 ỎCTYL-2-HYDROXYBENZAMIDE UTILISES EN TANT QU'ANTAGONISTES DU RECEPTEUR OPIOIDE MU | Entry into regional phase | 18.02.2010 | National basic fee paid | 18.02.2010 | Designation fee(s) paid | 18.02.2010 | Examination fee paid | Examination procedure | 18.02.2010 | Amendment by applicant (claims and/or description) | 18.02.2010 | Examination requested [2010/19] | 25.02.2013 | Despatch of a communication from the examining division (Time limit: M04) | 17.06.2013 | Reply to a communication from the examining division | 03.09.2013 | Communication of intention to grant the patent | 10.01.2014 | Fee for grant paid | 10.01.2014 | Fee for publishing/printing paid | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 25.02.2013 | Opposition(s) | 27.11.2014 | No opposition filed within time limit [2015/06] | Fees paid | Renewal fee | 25.08.2010 | Renewal fee patent year 03 | 25.08.2011 | Renewal fee patent year 04 | 27.08.2012 | Renewal fee patent year 05 | 27.08.2013 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 26.08.2008 | AT | 26.02.2014 | BG | 26.02.2014 | CY | 26.02.2014 | CZ | 26.02.2014 | DK | 26.02.2014 | EE | 26.02.2014 | FI | 26.02.2014 | HR | 26.02.2014 | LT | 26.02.2014 | LV | 26.02.2014 | MC | 26.02.2014 | MT | 26.02.2014 | NL | 26.02.2014 | PL | 26.02.2014 | RO | 26.02.2014 | SE | 26.02.2014 | SI | 26.02.2014 | SK | 26.02.2014 | TR | 26.02.2014 | NO | 26.05.2014 | GR | 27.05.2014 | IS | 26.06.2014 | PT | 26.06.2014 | LU | 26.08.2014 | [2016/33] |
Former [2016/32] | HU | 26.08.2008 | |
AT | 26.02.2014 | ||
BG | 26.02.2014 | ||
CY | 26.02.2014 | ||
CZ | 26.02.2014 | ||
DK | 26.02.2014 | ||
EE | 26.02.2014 | ||
FI | 26.02.2014 | ||
HR | 26.02.2014 | ||
LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
MC | 26.02.2014 | ||
MT | 26.02.2014 | ||
NL | 26.02.2014 | ||
PL | 26.02.2014 | ||
RO | 26.02.2014 | ||
SE | 26.02.2014 | ||
SI | 26.02.2014 | ||
SK | 26.02.2014 | ||
NO | 26.05.2014 | ||
GR | 27.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
LU | 26.08.2014 | ||
Former [2016/28] | AT | 26.02.2014 | |
BG | 26.02.2014 | ||
CY | 26.02.2014 | ||
CZ | 26.02.2014 | ||
DK | 26.02.2014 | ||
EE | 26.02.2014 | ||
FI | 26.02.2014 | ||
HR | 26.02.2014 | ||
LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
MC | 26.02.2014 | ||
MT | 26.02.2014 | ||
NL | 26.02.2014 | ||
PL | 26.02.2014 | ||
RO | 26.02.2014 | ||
SE | 26.02.2014 | ||
SI | 26.02.2014 | ||
SK | 26.02.2014 | ||
NO | 26.05.2014 | ||
GR | 27.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
LU | 26.08.2014 | ||
Former [2016/25] | AT | 26.02.2014 | |
BG | 26.02.2014 | ||
CY | 26.02.2014 | ||
CZ | 26.02.2014 | ||
DK | 26.02.2014 | ||
EE | 26.02.2014 | ||
FI | 26.02.2014 | ||
HR | 26.02.2014 | ||
LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
MC | 26.02.2014 | ||
NL | 26.02.2014 | ||
PL | 26.02.2014 | ||
RO | 26.02.2014 | ||
SE | 26.02.2014 | ||
SI | 26.02.2014 | ||
SK | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
LU | 26.08.2014 | ||
Former [2015/24] | AT | 26.02.2014 | |
CY | 26.02.2014 | ||
CZ | 26.02.2014 | ||
DK | 26.02.2014 | ||
EE | 26.02.2014 | ||
FI | 26.02.2014 | ||
HR | 26.02.2014 | ||
LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
MC | 26.02.2014 | ||
NL | 26.02.2014 | ||
PL | 26.02.2014 | ||
RO | 26.02.2014 | ||
SE | 26.02.2014 | ||
SI | 26.02.2014 | ||
SK | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
LU | 26.08.2014 | ||
Former [2015/19] | AT | 26.02.2014 | |
CY | 26.02.2014 | ||
CZ | 26.02.2014 | ||
DK | 26.02.2014 | ||
EE | 26.02.2014 | ||
FI | 26.02.2014 | ||
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LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
MC | 26.02.2014 | ||
NL | 26.02.2014 | ||
PL | 26.02.2014 | ||
RO | 26.02.2014 | ||
SE | 26.02.2014 | ||
SK | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
LU | 26.08.2014 | ||
Former [2015/18] | AT | 26.02.2014 | |
CY | 26.02.2014 | ||
CZ | 26.02.2014 | ||
DK | 26.02.2014 | ||
EE | 26.02.2014 | ||
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PL | 26.02.2014 | ||
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SE | 26.02.2014 | ||
SK | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
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CZ | 26.02.2014 | ||
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PL | 26.02.2014 | ||
RO | 26.02.2014 | ||
SE | 26.02.2014 | ||
SK | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
Former [2014/49] | AT | 26.02.2014 | |
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CZ | 26.02.2014 | ||
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LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
NL | 26.02.2014 | ||
RO | 26.02.2014 | ||
SE | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
Former [2014/48] | AT | 26.02.2014 | |
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CZ | 26.02.2014 | ||
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LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
NL | 26.02.2014 | ||
SE | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
Former [2014/41] | AT | 26.02.2014 | |
CY | 26.02.2014 | ||
FI | 26.02.2014 | ||
HR | 26.02.2014 | ||
LT | 26.02.2014 | ||
LV | 26.02.2014 | ||
NL | 26.02.2014 | ||
SE | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
Former [2014/39] | AT | 26.02.2014 | |
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FI | 26.02.2014 | ||
LT | 26.02.2014 | ||
NL | 26.02.2014 | ||
SE | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
Former [2014/37] | AT | 26.02.2014 | |
CY | 26.02.2014 | ||
FI | 26.02.2014 | ||
LT | 26.02.2014 | ||
SE | 26.02.2014 | ||
NO | 26.05.2014 | ||
IS | 26.06.2014 | ||
PT | 26.06.2014 | ||
Former [2014/36] | LT | 26.02.2014 | |
NO | 26.05.2014 | ||
IS | 26.06.2014 | Cited in | International search | [A]WO2004089908 (PFIZER PROD INC [US], et al) [A] 1,14-20 * example -; claims 1-3,10-12 *; | [A]WO2004089909 (PFIZER PROD INC [US], et al) [A] 1,14-20 * example -; claims 1,16,17 *; | [AP]WO2007103187 (THERAVANCE INC [US], et al) [AP] 1,2,5,8,9,11,13-21 * claims 1,8,15-26 * | [A] - ZHIJAN LU ET AL, "Substituted Bridged Phenyl Piperidines: Orally Active Growth Hormone Secretagogues", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB, (20030101), vol. 13, ISSN 0960-894X, pages 1817 - 1820, XP002449068 [A] 1 * page 1819, scheme 4; table 1 * DOI: http://dx.doi.org/10.1016/S0960-894X(03)00261-0 | by applicant | WO2004089908 | WO2004089909 | WO2007103187 | - BIOORG. AND MED. CHEM. LETT., (2003), vol. 13, pages 1817 - 1820 |