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Extract from the Register of European Patents

EP About this file: EP2220506

EP2220506 - BIOMARKERS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.08.2014
Database last updated on 20.07.2024
Most recent event   Tooltip10.06.2016Change - lapse in a contracting state
Updated state(s): GR
published on 13.07.2016  [2016/28]
Applicant(s)For all designated states
Vermillion, Inc.
12117 Bee Cave Road
Building Two, Suite 100
Austin, TX 78731 / US
For all designated states
The Board of Regents, The University of Texas System
201 West 7th Street
Austin, TX 78701 / US
[2012/03]
Former [2010/34]For all designated states
Vermillion, Inc.
47350 Fremont Blvd.
Fremont, CA 94538-6501 / US
For all designated states
The Board of Regents, The University of Texas System
201 West 7th Street
Austin, TX 78701 / US
Inventor(s)01 / FUNG, Eric, Thomas
271 De Anza Lane
Los Altos, CA 94022 / US
02 / CLARKE, Charlotte
2534 La Rochelle Court
Seabrook, TX 77586 / US
03 / BAST, Robert
1515 Holcombe Boulevard
Unit 0355
Houston, TX 77030 / US
04 / COOMBES, Kevin
1515 Holcombe Boulevard
Unit 1410
Houston, TX 77030 / US
 [2013/40]
Former [2010/35]01 / FUNG, Eric, Thomas
271 De Anza Lane
Los Altos, CA 94022 / US
02 / CLARKE, Charlotte
2534 La Rochelle Court
Seabrook, TX 77586 / US
03 / BAST, Robert
1515 Holcombe Boulevard Unit 0355
Houston, TX 77030 / US
04 / COOMBES, Kevin
1515 Holcombe Boulevard Unit 1410
Houston, TX 77030 / US
Former [2010/34]01 / FUNG, Eric, Thomas
271 De Anza Lane
Los Altos CA 94022 / US
02 / CLARKE, Charlotte
2534 La Rochelle Court
Seabrook TX 77586 / US
03 / BAST, Robert
1515 Holcombe Boulevard Unit 0355
Houston TX 77030 / US
04 / COOMBES, Kevin
1515 Holcombe Boulevard Unit 1410
Houston TX 77030 / US
Representative(s)Hiebl, Inge Elisabeth, et al
Kraus & Weisert
Patentanwälte PartGmbB
Thomas-Wimmer-Ring 15
80539 München / DE
[N/P]
Former [2010/34]Hiebl, Inge Elisabeth, et al
Kraus & Weisert Patent- und Rechtsanwälte Thomas-Wimmer-Ring 15
80539 München / DE
Application number, filing date08843957.529.10.2008
[2010/34]
WO2008US12323
Priority number, dateUS20070983378P29.10.2007         Original published format: US 983378 P
[2010/34]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2009058331
Date:07.05.2009
Language:EN
[2009/19]
Type: A2 Application without search report 
No.:EP2220506
Date:25.08.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 07.05.2009 takes the place of the publication of the European patent application.
[2010/34]
Type: B1 Patent specification 
No.:EP2220506
Date:02.10.2013
Language:EN
[2013/40]
Search report(s)International search report - published on:KR16.07.2009
(Supplementary) European search report - dispatched on:EP23.02.2011
ClassificationIPC:G01N33/50, G01N33/68, C12Q1/34
[2013/20]
CPC:
G01N33/57449 (EP,US); G01N33/6848 (EP,US); G01N2800/56 (EP,US)
Former IPC [2010/34]G01N33/574, G01N33/68, G01N33/53, G01N33/48, G01N33/50
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/34]
Extension statesALNot yet paid
BANot yet paid
MKNot yet paid
RSNot yet paid
TitleGerman:BIOMARKER ZUM NACHWEIS VON OVARIALKARZINOM IM FRÜHSTADIUM[2010/34]
English:BIOMARKERS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER[2010/34]
French:BIOMARQUEURS PERMETTANT LA DÉTECTION DU CANCER DES OVAIRES À UN STADE PRÉCOCE[2010/34]
Entry into regional phase27.05.2010National basic fee paid 
27.05.2010Search fee paid 
27.05.2010Designation fee(s) paid 
27.05.2010Examination fee paid 
Examination procedure27.05.2010Examination requested  [2010/34]
22.09.2011Amendment by applicant (claims and/or description)
28.10.2011Despatch of a communication from the examining division (Time limit: M02)
16.12.2011Reply to a communication from the examining division
31.01.2012Despatch of a communication from the examining division (Time limit: M04)
30.05.2012Reply to a communication from the examining division
10.04.2013Cancellation of oral proceeding that was planned for 18.04.2013
18.04.2013Date of oral proceedings (cancelled)
23.04.2013Communication of intention to grant the patent
21.08.2013Fee for grant paid
21.08.2013Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  28.10.2011
Opposition(s)03.07.2014No opposition filed within time limit [2014/37]
Fees paidRenewal fee
25.10.2010Renewal fee patent year 03
25.10.2011Renewal fee patent year 04
25.10.2012Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU29.10.2008
AT02.10.2013
BE02.10.2013
BG02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MT02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
TR02.10.2013
IE29.10.2013
LU29.10.2013
CH31.10.2013
LI31.10.2013
NO01.01.2014
GR03.01.2014
IS02.02.2014
PT03.02.2014
[2016/28]
Former [2016/21]HU29.10.2008
AT02.10.2013
BE02.10.2013
BG02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
GR02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MT02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
TR02.10.2013
IE29.10.2013
LU29.10.2013
CH31.10.2013
LI31.10.2013
NO01.01.2014
IS02.02.2014
PT03.02.2014
Former [2015/41]HU29.10.2008
AT02.10.2013
BE02.10.2013
BG02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
GR02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
MT02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
TR02.10.2013
IE29.10.2013
LU29.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2015/38]HU29.10.2008
AT02.10.2013
BE02.10.2013
BG02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
GR02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
TR02.10.2013
IE29.10.2013
LU29.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2015/34]HU29.10.2008
AT02.10.2013
BE02.10.2013
BG02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
TR02.10.2013
IE29.10.2013
LU29.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2015/32]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
TR02.10.2013
IE29.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/48]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
IE29.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/41]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
DK02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/38]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
IT02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/37]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
RO02.10.2013
SE02.10.2013
SI02.10.2013
SK02.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/36]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
EE02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
SE02.10.2013
SI02.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/34]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
SE02.10.2013
SI02.10.2013
CH31.10.2013
LI31.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/33]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
MC02.10.2013
NL02.10.2013
PL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/28]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
PL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
PT03.02.2014
Former [2014/26]AT02.10.2013
BE02.10.2013
CY02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
PL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/25]AT02.10.2013
BE02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
LV02.10.2013
NL02.10.2013
PL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/24]AT02.10.2013
BE02.10.2013
CZ02.10.2013
ES02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
NL02.10.2013
PL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/23]BE02.10.2013
CZ02.10.2013
FI02.10.2013
HR02.10.2013
LT02.10.2013
NL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
IS02.02.2014
Former [2014/22]FI02.10.2013
LT02.10.2013
NL02.10.2013
SE02.10.2013
SI02.10.2013
NO02.01.2014
Former [2014/20]LT02.10.2013
SI02.10.2013
NO02.01.2014
Former [2014/12]SI02.10.2013
Documents cited:Search[X]US2007054329  (FUNG ERIC T [US], et al) [X] 1-11 * par.13, 25, 130-133, 154-163, 199-201 *;
 [X]WO2007002535  (CIPHERGEN BIOSYSTEMS INC [US], et al) [X] 1-11 * par.10-12, 91-94, 122-127, table 2 *;
 [A]WO2005098446  (UNIV JOHNS HOPKINS [US], et al) [A] 1-11
 [Y]  - FENG SU ET AL, "Validation of Candidate Serum Ovarian Cancer Biomarkers for Early Detection", BIOMARKER INSIGHTS, LIBERTAS ACADEMICA LTD, NEW ZEALAND, (20070101), vol. 2, ISSN 1177-2719, pages 369 - 375, XP007916996 [Y] 1-9 * abstract; table 2 & 3 *
 [Y]  - ZHANG Z ET AL, "THREE BIOMARKERS IDENTIFIED FROM SERUM PROTEOMIC ANALYSIS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER REREARCH, US, (20040815), vol. 64, no. 16, doi:DOI:10.1158/0008-5472.CAN-04-0746, ISSN 0008-5472, pages 5882 - 5890, XP001199859 [Y] 1-9 * abstract *

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-04-0746
International search[A]WO2006099126  (CIPHERGEN BIOSYSTEMS INC [US], et al);
 [A]WO2007002264  (UNIV JOHNS HOPKINS [US], et al);
 [A]WO2006019906  (UNIV CALIFORNIA [US], et al);
 [A]US2005059013  (CHAN DANIEL W [US], et al);
 [AP]WO2008048508  (VERMILLION INC, et al)
Examination   - ROBERT E. GERSZTEN ET AL, "The search for new cardiovascular biomarkers", NATURE, (20080221), vol. 451, no. 7181, doi:10.1038/nature06802, ISSN 0028-0836, pages 949 - 952, XP055033236

DOI:   http://dx.doi.org/10.1038/nature06802
    - GREG P BERTENSHAW ET AL, "Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer", CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION, PHILADELPHIA, PA, US, (20081001), vol. 17, no. 10, doi:10.1158/1055-9965.EPI-08-0464, ISSN 1055-9965, pages 2872 - 2881, XP002624682

DOI:   http://dx.doi.org/10.1158/1055-9965.epi-08-0464
by applicantUS5719060
 US6225047
 WO0066265
 WO0067293
 US2003032043
 WO2005098447
 US2005059013
 WO03057014
 WO2004012588
 US2005214760
 US2002138208
 WO0131580
 US2002193950
 US2003004402
 US7113896
    - JAMAL, A. ET AL., CA CANCER J. CLIN, (2002), vol. 52, pages 23 - 47
    - BAST, R.C. ET AL., INT J BIOL MARKERS, (1998), vol. 13, pages 179 - 87
    - FUNG ET AL., INT. J. CANCER, (2005), vol. 115, pages 783 - 789
    - JAIN, "Statistical Pattern Recognition: A Review", IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, (200001), vol. 22, no. 1
 US20060495842
 WO2006US08578
 US20050693324
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.