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Extract from the Register of European Patents

EP About this file: EP2232244

EP2232244 - SUB-DIFFRACTION LIMIT IMAGE RESOLUTION IN THREE DIMENSIONS [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  22.07.2022
Database last updated on 09.09.2024
Most recent event   Tooltip22.07.2022Withdrawal of applicationpublished on 24.08.2022  [2022/34]
Applicant(s)For all designated states
President and Fellows of Harvard College
17 Quincy Street
Cambridge, MA 02138 / US
[2010/39]
Inventor(s)01 / ZHUANG, Xiaowei
12 Oxford Street
Cambridge MA 02138 / US
02 / HUANG, Bo
47 Stone Avenue, 1
Somerville, MA 02143 / US
03 / BATES, Wilfred, M.
88 Bay State Ave., 2
Somerville MA 02144 / US
04 / WANG, Wenqin
7 Beckwith Circle, 2
Somerville, MA 02143 / US
 [2010/39]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[N/P]
Former [2010/39]HOFFMANN EITLE
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München / DE
Application number, filing date08866669.819.12.2008
[2010/39]
WO2008US13915
Priority number, dateUS2007000866121.12.2007         Original published format: US 8661
[2010/39]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009085218
Date:09.07.2009
Language:EN
[2009/28]
Type: A1 Application with search report 
No.:EP2232244
Date:29.09.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 09.07.2009 takes the place of the publication of the European patent application.
[2010/39]
Search report(s)International search report - published on:EP09.07.2009
ClassificationIPC:G01N21/64
[2010/39]
CPC:
G01N21/6428 (EP,CN,US); H04N13/204 (US); G01N21/64 (US);
G01N21/6458 (EP,CN,US); G02B21/16 (EP,CN,US); G02B21/361 (EP,CN,US);
G02B21/367 (EP,CN,US); G02B27/58 (EP,CN,US); H04N7/18 (US);
G01N2021/6419 (EP,CN,US); G01N2021/6421 (EP,CN,US); G01N2021/6439 (US);
G01N2021/6441 (EP,CN,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2010/39]
TitleGerman:BILDAUFLÖSUNG UNTERHALB DER BEUGUNGSGRENZE IN DREI DIMENSIONEN[2010/39]
English:SUB-DIFFRACTION LIMIT IMAGE RESOLUTION IN THREE DIMENSIONS[2010/39]
French:RÉSOLUTION D'IMAGE EN LIMITE DE SOUS-DIFFRACTION EN TROIS DIMENSIONS[2010/39]
Entry into regional phase20.07.2010National basic fee paid 
20.07.2010Designation fee(s) paid 
20.07.2010Examination fee paid 
Examination procedure20.07.2010Examination requested  [2010/39]
20.09.2010Amendment by applicant (claims and/or description)
07.03.2016Despatch of a communication from the examining division (Time limit: M06)
08.09.2016Reply to a communication from the examining division
17.09.2018Date of oral proceedings
28.09.2018Minutes of oral proceedings despatched
01.10.2018Despatch of communication that the application is refused, reason: substantive examination {1}
09.05.2022Application withdrawn by applicant  [2022/34]
Appeal following examination03.12.2018Appeal received No.  T0671/19
11.02.2019Statement of grounds filed
09.05.2022Result of appeal procedure: the application was withdrawn
Divisional application(s)EP22172052.7
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  07.03.2016
Fees paidRenewal fee
27.12.2010Renewal fee patent year 03
27.12.2011Renewal fee patent year 04
26.12.2012Renewal fee patent year 05
27.12.2013Renewal fee patent year 06
29.12.2014Renewal fee patent year 07
28.12.2015Renewal fee patent year 08
27.12.2016Renewal fee patent year 09
27.12.2017Renewal fee patent year 10
31.12.2018Renewal fee patent year 11
27.12.2019Renewal fee patent year 12
28.12.2020Renewal fee patent year 13
27.12.2021Renewal fee patent year 14
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Cited inInternational search[X]  - OIJEN VAN A M ET AL, "3-DIMENSIONAL SUPER-RESOLUTION BY SPECTRALLY SELECTIVE IMAGING", CHEMICAL PHYSICS LETTERS, NORTH-HOLLAND, AMSTERDAM, (19980731), vol. 292, no. 1/02, ISSN 0009-2614, pages 183 - 187, XP001146248 [X] 1-8,28,29,32,37-45,48-54,63,64,67-74,77 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0009-2614(98)00673-3
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DOI:   http://dx.doi.org/10.1126/SCIENCE.1127344
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DOI:   http://dx.doi.org/10.1529/BIOPHYSJ.106.091116
 [XY]  - LACOSTE T D ET AL, "Ultrahigh-resolution multicolor colocalization of single fluorescent probes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC.; US, (20000815), vol. 97, no. 17, ISSN 0027-8424, pages 9461 - 9466, XP002458687 [X] 1-4,49,50 * the whole document * [Y] 5-48,51-77

DOI:   http://dx.doi.org/10.1073/pnas.170286097
 [XY]  - RUST M J ET AL, "Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)", NATURE METHODS, NATURE PUBLISHING GROUP, GB, vol. 3, no. 10, ISSN 1548-7091, (20060809), pages 793 - 795, (20060809), XP002492582 [X] 1-4,49,51 * the whole document * [Y] 5-48,51-77

DOI:   http://dx.doi.org/10.1038/nmeth929
 [XY]  - BATES M ET AL, "Multicolor Super-Resolution Imaging with Photo-Switchable Fluorescent Probes", SCIENCE, vol. 317, no. 5845, pages 1749 - 1753, URL: http://www.sciencemag.org/cgi/content/abstract/317/5845/1749, (20070921), XP002515308 [X] 1-4,49,50 * the whole document * [Y] 5-48,51-77

DOI:   http://dx.doi.org/10.1126/science.1146598
 [Y]  - SPEIDEL M ET AL, "Three-dimensional tracking of fluorescent nanoparticles with subnanometer precision by use of off-focus imaging", OPTICS LETTERS, OSA, OPTICAL SOCIETY OF AMERICA, WASHINGTON, DC, US, (20030115), vol. 28, no. 2, ISSN 0146-9592, pages 69 - 71, XP002436568 [Y] 5-48,51-77 * the whole document *

DOI:   http://dx.doi.org/10.1364/OL.28.000069
 [Y]  - KAO H P AND VERKMAN A S, "Tracking of Single Fluorescent Particles in Three Dimensions: Use of Cylindrical Optics to Encode Particle Position", BIOPHYSICAL JOURNAL, (199409), vol. 67, pages 1291 - 1300, XP002523344 [Y] 5-48,51-77 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0006-3495(94)80601-0
 [Y]  - TOPRAK E ET AL, "Three-Dimensional Particle Tracking via Bifocal Imaging", NANO LETTERS, (20070621), vol. 7, no. 7, pages 2043 - 2045, XP002523345 [Y] 5-48,51-77 * the whole document *

DOI:   http://dx.doi.org/10.1021/NL0709120
 [Y]  - PRABHAT P ET AL, "Simultaneous imaging of several focal planes in fluorescence microscopy for the study of cellular dynamics in 3D", PROC. SPIE, (2006), vol. 6090, pages 60900L-1 - 60900L-7, XP002523346 [Y] 5-48,51-77 * abstract *

DOI:   http://dx.doi.org/10.1117/12.644343
 [PX]  - BATES M ET AL, "Super-resolution microscopy by nanoscale localization of photo-switchable fluorescent probes", CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, vol. 12, no. 5, ISSN 1367-5931, (20081001), pages 505 - 514, (20080920), XP025561452 [PX] 1-77 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.cbpa.2008.08.008
 [PX]  - HUANG B ET AL, "Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy", SCIENCE, (20080208), vol. 319, pages 810 - 813, XP002523347 [PX] 1-77 * the whole document *

DOI:   http://dx.doi.org/10.1126/SCIENCE.1153529
 [PX]  - JUETTE M F ET AL, "Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples", NATURE METHODS, (200806), vol. 5, no. 6, pages 527 - 529, XP002523348 [PX] 1-77 * the whole document *

DOI:   http://dx.doi.org/10.1038/NMETH.1211
ExaminationWO2006127692
    - HOLTZER LAURENT ET AL, "Nanometric three-dimensional tracking of individual quantum dots in cells", APPLIED PHYSICS LETTERS, A I P PUBLISHING LLC, US, (20070201), vol. 90, no. 5, doi:10.1063/1.2437066, ISSN 0003-6951, pages 53902 - 053902, XP012095875

DOI:   http://dx.doi.org/10.1063/1.2437066
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