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Extract from the Register of European Patents

EP About this file: EP2186525

EP2186525 - G-CSF for use in the treatment of Parkinson's disease [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.01.2012
Database last updated on 02.08.2024
Most recent event   Tooltip06.01.2012Application deemed to be withdrawnpublished on 08.02.2012  [2012/06]
Applicant(s)For all designated states
SYGNIS Bioscience GmbH & Co KG
Im Neuenheimer Feld 515
69120 Heidelberg / DE
[2010/20]
Inventor(s)01 / Schäbitz, Wolf-Rüdiger
Johannistal 22A
33617 Bielefeld / DE
02 / Schneider, Armin
Am Büchsenackerhang 69
69118 Heidelberg / DE
03 / Krüger, Carola
Trifelstr. 1
67434 Neustadt/Weinstrasse / DE
04 / Sommer, Clemens
Weinbergring 21
55268 Nieder-Olm / DE
05 / Schwab, Stefan
Atzelsberger Steige 16
91054 Erlangen / DE
06 / Kollmar, Rainer
Robert-Gradmann-Str. 2
91054 Erlangen / DE
07 / Maurer, Martin
Primus-Truberstr. 6
72072 Tübingen / DE
08 / Weber, Daniela
Wundtstr. 19
69123 Heidelberg / DE
09 / Gassler, Nikolaus
Bleibergerstr. 160
52074 Aachen / DE
 [2010/20]
Representative(s)Lahrtz, Fritz
Isenbruck Bösl Hörschler LLP
Eastsite One
Seckenheimer Landstrasse 4
68163 Mannheim / DE
[N/P]
Former [2010/20]Lahrtz, Fritz
Isenbruck Bösl Hörschler Wichmann LLP Eastsite One Seckenheimer Landstrasse 4
68163 Mannheim / DE
Application number, filing date09011942.131.12.2003
[2010/20]
Priority number, dateUS2002033175531.12.2002         Original published format: US 331755
US2003065929511.09.2003         Original published format: US 659295
[2010/20]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP2186525
Date:19.05.2010
Language:EN
[2010/20]
Type: A3 Search report 
No.:EP2186525
Date:09.02.2011
[2011/06]
Search report(s)(Supplementary) European search report - dispatched on:EP12.01.2011
ClassificationIPC:A61K38/19, G01N33/50, A61P25/28
[2011/06]
CPC:
G01N33/5008 (EP,US); A61K38/193 (EP,US); A61K38/49 (EP,US);
A61P21/00 (EP); A61P25/00 (EP); A61P25/14 (EP);
A61P25/16 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P9/00 (EP); A61P9/10 (EP);
G01N33/5023 (EP,US); G01N33/5041 (EP,US); G01N33/5058 (EP,US);
G01N33/6872 (EP,US) (-)
C-Set:
A61K38/193, A61K2300/00 (EP,US);
A61K38/49, A61K2300/00 (US,EP)
Former IPC [2010/20]A61K38/19, A61P25/16
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2010/20]
TitleGerman:G-CSF zur Behandlung der Parkinson-Krankheit[2010/20]
English:G-CSF for use in the treatment of Parkinson's disease[2010/20]
French:G-CSF pour son utilisation dans le traitement de la maladie de Parkinson[2010/20]
Examination procedure18.09.2009Examination requested  [2010/20]
10.08.2011Application deemed to be withdrawn, date of legal effect  [2012/06]
21.09.2011Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2012/06]
Parent application(s)   TooltipEP03799727.7  / EP1581249
Divisional application(s)EP10011006.3  / EP2311483
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20030799727) is  06.04.2006
Fees paidRenewal fee
18.09.2009Renewal fee patent year 03
18.09.2009Renewal fee patent year 04
18.09.2009Renewal fee patent year 05
18.09.2009Renewal fee patent year 06
29.01.2010Renewal fee patent year 07
28.12.2010Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.12.200907   M06   Fee paid on   29.01.2010
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XI]CA2213906  (FEDOROFF SERGEY [CA], et al) [X] 1-5 * claims 1-18 *[I] 1-5;
 [XI]DE10033219  (UNIV HEIDELBERG [DE]) [X] 1,2,5 * the whole document * [I] 1-5;
 [Y]US2002151488  (SARKAR CASIM A [US], et al) [Y] 1-5 * paragraphs [0028] , [0032] , [0034] , [0037] , [0135] , [0149] - [0154] - [0185] * * example 2 * * claims 1-18 *;
 [XI]WO02099081  (QUARK BIOTECH INC [US], et al) [X] 1-5 * claims 1-17 * * page 12, lines 13-19 * * the whole document * * page 6, line 15 * [I] 1-5;
 [IP]WO03061685  (POURQUIER DIDIER [FR], et al) [IP] 1-5 * claims 1-12 * * the whole document *;
 [E]EP1374898  (INST OF GENE AND BRAIN SCIENCE [JP]) [E] 1-5 * claims 4-6 * * examples 5,13,14 *;
 [Y]  - SCHAEBITZ W R ET AL, "RECOMBINANT GRANULOCYTE-COLONY STIMULATING FACTOR (RG-CSF) IS NEUROPROTECTIVE FOLLOWING FOCAL TRANSIENT CEREBRAL ISCHEMIA AND EXCITOTOXITY", SOCIETY FOR NEUROSCIENCE ABSTRACTS, SOCIETY FOR NEUROSCIENCE, US, (20011110), vol. 27, no. PART 2, ISSN 0190-5295, XP008009334 [Y] 1-5 * the whole document *
 [Y]  - KONISHI Y ET AL, "Trophic effect of erythropoietin and other hematopoietic factors on central cholinergic neurons in vitro and in vivo.", BRAIN RESEARCH. 23 APR 1993, (19930423), vol. 609, no. 1-2, ISSN 0006-8993, pages 29 - 35, XP001183386 [Y] 1-5 * abstract * * Introduction, page 29 * * Discussion pages 32-34 *

DOI:   http://dx.doi.org/10.1016/0006-8993(93)90850-M
 [Y]  - HIERHOLZER C ET AL, "Activation of STAT proteins following ischemia reperfusion injury demonstrates a distinct IL-6 and G-CSF mediated profile.", TRANSPLANTATION PROCEEDINGS. SEP 1998, (199809), vol. 30, no. 6, ISSN 0041-1345, page 2647, XP001182894 [Y] 1-5 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0041-1345(98)00771-4
 [Y]  - TIAN SHIN-SHAY ET AL, "Multiple signaling pathways induced by granulocyte colony-stimulating factor involving activation of JAKs, STAT5, and/or STAT3 are required for regulation of three distinct classes of immediate early genes", BLOOD, (1996), vol. 88, no. 12, ISSN 0006-4971, pages 4435 - 4444, XP001183387 [Y] 1-5 * the whole document *
 [Y]  - WARD ALISTER C ET AL, "Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration", BLOOD, (19990101), vol. 93, no. 1, ISSN 0006-4971, pages 113 - 124, XP001183113 [Y] 1-5 * the whole document *
 [T]  - SCHAEBITZ W -R ET AL, "Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia.", STROKE, (200303), vol. 34, no. 3, ISSN 0039-2499, pages 745 - 751, XP002294803 [T] 1-5 * the whole document *

DOI:   http://dx.doi.org/10.1161/01.STR.0000057814.70180.17
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