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Extract from the Register of European Patents

EP About this file: EP2174954

EP2174954 - Hematopoietic cell e-selectin/l-selectin ligand polypeptides and methods of use thereof [Right-click to bookmark this link]
Former [2010/15]Hematopoietic cell e-selection/l-selectin ligand polypeptides and methods of use thereof
[2015/13]
StatusNo opposition filed within time limit
Status updated on  27.01.2017
Database last updated on 24.04.2024
Most recent event   Tooltip13.07.2018Lapse of the patent in a contracting state
New state(s): CY, MC, TR		published on 15.08.2018  [2018/33]
Applicant(s)For all designated states
Sackstein, Robert
26 Fox Run Road
Sudbury MA 01776 / US
[2012/37]
Former [2010/15]For all designated states
The Brigham and Women's Hospital, Inc.
75 Francis Street
Boston MA 02115 / US
Inventor(s)01 / see applicant
...
 [2012/37]
Former [2010/15]01 / Sackstein, Robert
26 Fox Run Road
Sudbury, MA 01776 / US
Representative(s)Williams, Andrea, et al
Marks & Clerk LLP
62-68 Hills Road
Cambridge CB2 1LA / GB
[2016/12]
Former [2010/15]Fleck, Barbara
Marks & Clerk LLP 62-68 Hills Road Cambridge
Cambridgeshire CB2 1LA / GB
Application number, filing date09180380.918.10.2001
[2010/15]
Priority number, dateUS20000240987P18.10.2000         Original published format: US 240987 P
US20010297474P10.06.2001         Original published format: US 297474 P
[2010/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2174954
Date:14.04.2010
Language:EN
[2010/15]
Type: B1 Patent specification 
No.:EP2174954
Date:23.03.2016
Language:EN
[2016/12]
Search report(s)(Supplementary) European search report - dispatched on:EP05.03.2010
ClassificationIPC:C07K14/705, C07K16/28, G01N33/68, C12N5/0789, A61K35/12
[2015/13]
CPC:
C12N5/0647 (EP,US); A61P1/04 (EP); A61P1/16 (EP);
A61P11/06 (EP); A61P19/02 (EP); A61P21/04 (EP);
A61P25/16 (EP); A61P29/00 (EP); A61P29/02 (EP);
A61P3/10 (EP); A61P35/00 (EP); A61P35/02 (EP);
A61P7/00 (EP); A61P9/00 (EP); A61P9/10 (EP);
C07K14/70585 (EP,US); A61K2035/124 (EP,US); C12N2501/59 (EP,US);
C12N2501/599 (US); C12N2501/724 (US); C12N2501/90 (US) (-)
Former IPC [2010/15]C07K14/705, C07K16/28, G01N33/68
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE,   TR [2016/12]
Former [2010/15]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE,  TR 
TitleGerman:E-Selectin/L-Selectin-Ligandenpolypeptide aus hämatopoetische Zellen und Verwendungsverfahren dafür[2015/13]
English:Hematopoietic cell e-selectin/l-selectin ligand polypeptides and methods of use thereof[2015/13]
French:Polypeptides ligands E-sélectine/L-sélectine de cellules hématopoïétiques et leurs procédés d'utilisation[2015/13]
Former [2010/15]Hämatopoetische E-Zellen-Auswahl/L-Selectin-Ligandenpolypeptide und Verwendungsverfahren dafür
Former [2010/15]Hematopoietic cell e-selection/l-selectin ligand polypeptides and methods of use thereof
Former [2010/15]Polypeptides ligands E/sélection/L sélectine de cellules hématopoïétiques et leurs procédés d'utilisation
Examination procedure22.12.2009Examination requested  [2010/15]
14.10.2010Amendment by applicant (claims and/or description)
08.12.2010Despatch of a communication from the examining division (Time limit: M04)
14.04.2011Reply to a communication from the examining division
04.10.2011Despatch of a communication from the examining division (Time limit: M04)
02.02.2012Reply to a communication from the examining division
09.07.2012Despatch of a communication from the examining division (Time limit: M06)
11.01.2013Reply to a communication from the examining division
29.07.2013Despatch of a communication from the examining division (Time limit: M06)
06.02.2014Reply to a communication from the examining division
29.04.2014Despatch of a communication from the examining division (Time limit: M04)
24.07.2014Reply to a communication from the examining division
11.11.2014Despatch of a communication from the examining division (Time limit: M04)
19.11.2014Reply to a communication from the examining division
26.03.2015Communication of intention to grant the patent
28.07.2015Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
11.09.2015Communication of intention to grant the patent
20.01.2016Fee for grant paid
20.01.2016Fee for publishing/printing paid
20.01.2016Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP01988458.4  / EP1421174
Divisional application(s)EP16161354.2  / EP3106467
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20010988458) is  04.12.2006
Opposition(s)02.01.2017No opposition filed within time limit [2017/09]
Fees paidRenewal fee
22.12.2009Renewal fee patent year 03
22.12.2009Renewal fee patent year 04
22.12.2009Renewal fee patent year 05
22.12.2009Renewal fee patent year 06
22.12.2009Renewal fee patent year 07
22.12.2009Renewal fee patent year 08
22.12.2009Renewal fee patent year 09
25.10.2010Renewal fee patent year 10
25.10.2011Renewal fee patent year 11
25.10.2012Renewal fee patent year 12
28.10.2013Renewal fee patent year 13
27.10.2014Renewal fee patent year 14
27.10.2015Renewal fee patent year 15
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT23.03.2016
CY23.03.2016
FI23.03.2016
MC23.03.2016
SE23.03.2016
TR23.03.2016
GR24.06.2016
PT25.07.2016
LU18.10.2016
[2018/29]
Former [2017/47]AT23.03.2016
FI23.03.2016
SE23.03.2016
GR24.06.2016
PT25.07.2016
LU18.10.2016
Former [2016/52]AT23.03.2016
FI23.03.2016
SE23.03.2016
GR24.06.2016
PT25.07.2016
Former [2016/50]AT23.03.2016
FI23.03.2016
SE23.03.2016
GR24.06.2016
Former [2016/39]FI23.03.2016
SE23.03.2016
GR24.06.2016
Former [2016/35]FI23.03.2016
GR24.06.2016
Documents cited:Search[X]  - OXLEY SUSAN M ET AL, "Detection of an L-selectin ligand on a hematopoietic progenitor cell line", BLOOD, (1994), vol. 84, no. 10, ISSN 0006-4971, pages 3299 - 3306, XP002288887 [X] 1-4,6,8-10,13-15 * page 3303, column R, paragraph 2 - page 3304, column R, paragraph 1; table 2 * * page 3305, column L, paragraph 3 *
 [X]  - SACKSTEIN ROBERT ET AL, "A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity", BLOOD, (20001015), vol. 96, no. 8, ISSN 0006-4971, pages 2765 - 2774, XP002288888 [X] 1-4,6,8-10,13-15 * page 2769, column R, paragraph 1 - page 2770, column L, paragraph 1 * * page 2773, column R, line 2 - line 4 *
 [XI]  - GREENBERG ADAM W ET AL, "Relationship between selectin-mediated rolling of hematopoietic stem and progenitor cells and progression in hematopoietic development", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (20000115), vol. 95, no. 2, ISSN 0006-4971, pages 478 - 486, XP002450253 [X] 5 * page 479, column 2, paragraph 4 - page 480, column 1, paragraph 1 * * page 480, column 1, paragraph 5 - page 485, column 2, paragraph 1 * [I] 7,11-12
 [XI]  - BORGES E ET AL, "The binding of T cell-expressed P-selectin glycoprotein ligand-1 to E- and P-selectin is differentially regulated.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 7 NOV 1997, (19971107), vol. 272, no. 45, ISSN 0021-9258, pages 28786 - 28792, XP002569716 [X] 1,3 * abstract * [I] 2

DOI:   http://dx.doi.org/10.1074/jbc.272.45.28786
 [A]  - GHAFFARI S ET AL, "CD44 isoforms in normal and leukemic hematopoiesis.", EXPERIMENTAL HEMATOLOGY JUN 1999, (199906), vol. 27, no. 6, ISSN 0301-472X, pages 978 - 993, XP002569717 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0301-472X(99)00023-5
 [XP]  - DIMITROFF CHARLES J ET AL, "A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (20001205), vol. 97, no. 25, ISSN 0027-8424, pages 13841 - 13846, XP002288889 [XP] 1-4,6,8-10,13-15 * page 13841, column R, paragraph 2 * * page 13844, column L, paragraph 2 *

DOI:   http://dx.doi.org/10.1073/pnas.250484797
 [XP]  - DIMITROFF CHARLES J ET AL, "CD44 is a major E-selectin ligand on human hematopoietic progenitor cells", JOURNAL OF CELL BIOLOGY, (20010611), vol. 153, no. 6, ISSN 0021-9525, pages 1277 - 1286, XP002288890 [XP] 1-4,6,8-10,13-15 * the whole document *

DOI:   http://dx.doi.org/10.1083/jcb.153.6.1277
 [T]  - SACKSTEIN ROBERT, "The bone marrow is akin to skin: HCELL and the biology of hematopoietic stem cell homing", JOURNAL OF INVESTIGATIVE DERMATOLOGY, (200405), vol. 122, no. 5, ISSN 0022-202X, pages 1061 - 1069, XP002288891 [T] 1-4,6,8-10,13-15 * page 1064, column L, paragraph 2 - column R, paragraph 1 *

DOI:   http://dx.doi.org/10.1111/j.0022-202X.2004.09301.x
Examination   - ZANNETTINO A C ET AL, Primitive human hematopoietic progenitors adhere to P-selectin (CD62P)., BLOOD 15 JUN 1995 LNKD- PUBMED:7540063, VOL. 85, NR. 12, PAGE(S) 3466 - 3477, (19950615), ISSN 0006-4971
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.