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Extract from the Register of European Patents

EP About this file: EP2245458

EP2245458 - A NEW METHOD TO MEASURE AND CHARACTERIZE MICROVESICLES IN THE HUMAN BODY FLUIDS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  01.09.2017
Database last updated on 03.09.2024
Most recent event   Tooltip15.11.2019Lapse of the patent in a contracting state
New state(s): MK
published on 18.12.2019  [2019/51]
Applicant(s)For all designated states
Exosomics Siena S.p.A.
Via Fiorentina 1
53100 Siena / IT
[2017/04]
Former [2016/43]For all designated states
Hansabiomed Oü
Aiavilja 3-5
90505 Haapsalu / EE
Former [2010/44]For all designated states
Hansabiomed Oü
Akadeemia tee 19
12618 Tallinn / EE
Inventor(s)01 / FAIS, Stefano
Via Svetonio 25
I-00136 Roma / IT
02 / LOGOZZI, Mariantonia
Via Riccardo Zampieri 27
I-00159 Roma / IT
 [2010/44]
Representative(s)Rambelli, Paolo, et al
Jacobacci & Partners S.p.A.
Corso Emilia 8
10152 Torino / IT
[2016/43]
Former [2010/44]Rambelli, Paolo, et al
Jacobacci & Partners S.p.A. Corso Emilia 8
10152 Torino / IT
Application number, filing date09704302.026.01.2009
[2010/44]
WO2009EE00002
Priority number, dateUS20080062528P25.01.2008         Original published format: US 62528 P
US2009032141221.01.2009         Original published format: US 321412
[2010/44]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2009092386
Date:30.07.2009
Language:EN
[2009/31]
Type: A2 Application without search report 
No.:EP2245458
Date:03.11.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 30.07.2009 takes the place of the publication of the European patent application.
[2010/44]
Type: B1 Patent specification 
No.:EP2245458
Date:26.10.2016
Language:EN
[2016/43]
Search report(s)International search report - published on:EP17.09.2009
ClassificationIPC:G01N33/53, G01N33/574, G01N33/569, G01N33/567
[2016/13]
CPC:
G01N33/567 (EP,US); G01N33/56988 (EP,US); G01N33/5743 (EP,US);
G01N2333/16 (EP,US); G01N2333/18 (EP,US); G01N2800/2828 (EP,US)
Former IPC [2010/44]G01N33/53, G01N33/574, G01N33/569
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2016/43]
Former [2010/44]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:NEUES VERFAHREN ZUR MESSUNG UND CHARAKTERISIERUNG VON MIKROVESIKELN IN MENSCHLICHEN KÖRPERFLÜSSIGKEITEN[2010/44]
English:A NEW METHOD TO MEASURE AND CHARACTERIZE MICROVESICLES IN THE HUMAN BODY FLUIDS[2010/44]
French:NOUVEAU PROCÉDÉ DE MESURE ET DE CARACTÉRISATION DE MICROVÉSICULES DANS DES LIQUIDES ORGANIQUES HUMAIN[2010/44]
Entry into regional phase09.08.2010National basic fee paid 
09.08.2010Designation fee(s) paid 
09.08.2010Examination fee paid 
Examination procedure09.08.2010Amendment by applicant (claims and/or description)
09.08.2010Examination requested  [2010/44]
26.10.2012Despatch of a communication from the examining division (Time limit: M04)
25.02.2013Reply to a communication from the examining division
20.12.2013Despatch of a communication from the examining division (Time limit: M08)
19.08.2014Reply to a communication from the examining division
24.11.2015Date of oral proceedings
03.12.2015Despatch of a communication from the examining division (Time limit: M02)
03.12.2015Minutes of oral proceedings despatched
05.02.2016Reply to a communication from the examining division
31.03.2016Communication of intention to grant the patent
05.07.2016Fee for grant paid
05.07.2016Fee for publishing/printing paid
01.08.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.10.2012
Opposition(s)27.07.2017No opposition filed within time limit [2017/40]
Fees paidRenewal fee
23.12.2010Renewal fee patent year 03
21.11.2011Renewal fee patent year 04
23.11.2012Renewal fee patent year 05
21.02.2014Renewal fee patent year 06
20.11.2014Renewal fee patent year 07
24.11.2015Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.01.201406   M06   Fee paid on   21.02.2014
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU26.01.2009
AT26.10.2016
BE26.10.2016
CY26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
MC26.10.2016
MK26.10.2016
NL26.10.2016
SI26.10.2016
SK26.10.2016
BG26.01.2017
IE26.01.2017
LU26.01.2017
MT26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
[2019/51]
Former [2019/46]HU26.01.2009
AT26.10.2016
BE26.10.2016
CY26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
MC26.10.2016
NL26.10.2016
SI26.10.2016
SK26.10.2016
BG26.01.2017
IE26.01.2017
LU26.01.2017
MT26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2019/31]HU26.01.2009
AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
MC26.10.2016
NL26.10.2016
SI26.10.2016
SK26.10.2016
BG26.01.2017
IE26.01.2017
LU26.01.2017
MT26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2018/43]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
MC26.10.2016
NL26.10.2016
SI26.10.2016
SK26.10.2016
BG26.01.2017
IE26.01.2017
LU26.01.2017
MT26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2018/13]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
MC26.10.2016
NL26.10.2016
SI26.10.2016
SK26.10.2016
BG26.01.2017
IE26.01.2017
LU26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/52]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
MC26.10.2016
NL26.10.2016
SI26.10.2016
SK26.10.2016
BG26.01.2017
LU26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/42]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
MC26.10.2016
NL26.10.2016
SK26.10.2016
BG26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/38]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
NL26.10.2016
SK26.10.2016
BG26.01.2017
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/36]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
NL26.10.2016
SK26.10.2016
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/35]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
EE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
NL26.10.2016
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/34]AT26.10.2016
BE26.10.2016
CZ26.10.2016
DK26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
NL26.10.2016
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/33]AT26.10.2016
BE26.10.2016
DK26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
NL26.10.2016
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/26]AT26.10.2016
BE26.10.2016
FI26.10.2016
HR26.10.2016
LT26.10.2016
LV26.10.2016
NL26.10.2016
NO26.01.2017
GR27.01.2017
IS26.02.2017
PT27.02.2017
Former [2017/12]LV26.10.2016
Cited inInternational search[Y]CA2453198  (ICHIM THOMAS EMANUEL [CA], et al) [Y] 1-12 * page 10 *;
 [Y]WO03063690  (BAYLOR COLLEGE MEDICINE [US], et al) [Y] 1-12 * abstract *;
 [Y]  - KOGA KENICHIRO ET AL, "Purification, characterization and biological significance of tumor-derived exosomes", ANTICANCER RESEARCH, (200511), vol. 25, no. 6A, ISSN 0250-7005, pages 3703 - 3707, XP002527286 [Y] 1-12 * page 3704 *
 [Y]  - ADMYRE ET AL, "B cell-derived exosomes can present allergen peptides and activate allergen-specific T cells to proliferate and produce TH2-like cytokines", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, MOSBY - YEARLY BOOK, INC, US, (20071201), vol. 120, no. 6, ISSN 0091-6749, pages 1418 - 1424, XP022383439 [Y] 1-12 * page 1420 * * page 1419 *

DOI:   http://dx.doi.org/10.1016/j.jaci.2007.06.040
 [T]  - LOGOZZI MARIANTONIA ET AL, "High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.", PLOS ONE 2009, (2009), vol. 4, no. 4, ISSN 1932-6203, page e5219, XP002527287 [T] 1-12 * the whole document *

DOI:   http://dx.doi.org/10.1371/journal.pone.0005219
 [Y]  - AOKI NAOHITO ET AL, "Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and HormoneDependent induction of milk fat globule-epidermal growth factor 8-associated microvesicles", ENDOCRINOLOGY, (200708), vol. 148, no. 8, ISSN 0013-7227, pages 3850 - 3862, XP002527288 [Y] 1-12 * page 3857 *

DOI:   http://dx.doi.org/10.1210/en.2006-1479
by applicantCA2453198
    - KOGA ET AL., ANTICANCER RES., (2005), vol. 25, pages 3703 - 3727
    - ADMYRE ET AL., J ALLERGY CLIN IMMUNOL, vol. 120, pages 1418 - 1423
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