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Extract from the Register of European Patents

EP About this file: EP2260054

EP2260054 - PURIFIED IMMUNOGLOBULIN FUSION PROTEINS AND METHODS OF THEIR PURIFICATION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.04.2016
Database last updated on 22.05.2024
Most recent event   Tooltip13.07.2018Lapse of the patent in a contracting state
Updated state(s): MT		published on 15.08.2018  [2018/33]
Applicant(s)For all designated states
Biogen MA Inc.
250 Binney Street
Cambridge, MA 02142 / US
[2015/24]
Former [2010/50]For all designated states
Biogen Idec MA Inc.
133 Boston Post Road
Weston, MA 02493 / US
Inventor(s)01 / MCCUE, Justin
48 Thomas Street
Belmont, MA 02478 / US
02 / ROMERO, Jonathan
432 Norfolk Street, 4H
Somerville MA 02143 / US
03 / MEIER, Werner
31 Bedford Street
Burlington MA 01803 / US
04 / NOTARNICOLA, Stephen
33 Coolidge Rd.
Medford MA 02155 / US
05 / EVANS, David
73 Nowell Road
Melrose, MA 02176 / US
06 / MACNIVEN, Richard
21 Forster Street, 3
Somerville MA 02145 / US
 [2015/23]
Former [2010/50]01 / MCCUE, Justin
64 Hurley Street Unit 2
Cambridge MA 02141 / US
02 / ROMERO, Jonathan
432 Norfolk Street, 4H
Somerville MA 02143 / US
03 / MEIER, Werner
31 Bedford Street
Burlington MA 01803 / US
04 / NOTARNICOLA, Stephen
33 Coolidge Rd.
Medford MA 02155 / US
05 / EVANS, David
5 Garrison Road
Arlington MA 02474 / US
06 / MACNIVEN, Richard
21 Forster Street, 3
Somerville MA 02145 / US
Representative(s)Adams, Harvey Vaughan John
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
[2015/23]
Former [2010/50]Adams, Harvey Vaughan John
Mathys & Squire LLP 120 Holborn London
EC1N 2SQ / GB
Application number, filing date09716313.327.02.2009
[2010/50]
WO2009US35581
Priority number, dateUS2008006785229.02.2008         Original published format: US 67852
US2008007410219.06.2008         Original published format: US 74102
[2010/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2009111347
Date:11.09.2009
Language:EN
[2009/37]
Type: A1 Application with search report 
No.:EP2260054
Date:15.12.2010
Language:EN
The application published by WIPO in one of the EPO official languages on 11.09.2009 takes the place of the publication of the European patent application.
[2010/50]
Type: B1 Patent specification 
No.:EP2260054
Date:03.06.2015
Language:EN
[2015/23]
Search report(s)International search report - published on:EP11.09.2009
ClassificationIPC:C07K14/715, C07K1/20, C12N15/62, C07K1/16
[2010/50]
CPC:
C07K14/7151 (EP,US); A61K47/6811 (EP,US); A61K47/6835 (EP,US);
A61P37/00 (EP); A61P37/06 (EP); C07K2319/30 (EP,US);
C07K2319/32 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2015/23]
Former [2010/50]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
Extension statesAL29.09.2010
BA29.09.2010
RS29.09.2010
TitleGerman:AUFGEREINIGTE IMMUNOGLOBULINFUSIONSPROTEINE UND VERFAHREN ZU IHRER AUFREINIGUNG[2010/50]
English:PURIFIED IMMUNOGLOBULIN FUSION PROTEINS AND METHODS OF THEIR PURIFICATION[2010/50]
French:PROTÉINES HYBRIDES PURIFIÉES D IMMUNOGLOBULINE ET LEURS PROCÉDÉS DE PURIFICATION[2010/50]
Entry into regional phase29.09.2010National basic fee paid 
29.09.2010Designation fee(s) paid 
29.09.2010Examination fee paid 
Examination procedure29.09.2010Amendment by applicant (claims and/or description)
29.09.2010Examination requested  [2010/50]
04.03.2011Despatch of a communication from the examining division (Time limit: M06)
14.09.2011Reply to a communication from the examining division
12.03.2012Despatch of a communication from the examining division (Time limit: M06)
21.09.2012Reply to a communication from the examining division
19.04.2013Despatch of a communication from the examining division (Time limit: M04)
22.08.2013Reply to a communication from the examining division
28.07.2014Communication of intention to grant the patent
05.12.2014Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
07.01.2015Communication of intention to grant the patent
24.04.2015Fee for grant paid
24.04.2015Fee for publishing/printing paid
24.04.2015Receipt of the translation of the claim(s)
Divisional application(s)EP13159051.5  / EP2615112
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.03.2011
Opposition(s)04.03.2016No opposition filed within time limit [2016/19]
Fees paidRenewal fee
23.02.2011Renewal fee patent year 03
24.02.2012Renewal fee patent year 04
27.02.2013Renewal fee patent year 05
27.02.2014Renewal fee patent year 06
26.02.2015Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.02.2009
AT03.06.2015
BE03.06.2015
CY03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
MK03.06.2015
NL03.06.2015
PL03.06.2015
RO03.06.2015
SE03.06.2015
SI03.06.2015
SK03.06.2015
TR03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
GB27.02.2016
IE27.02.2016
LU27.02.2016
CH29.02.2016
FR29.02.2016
LI29.02.2016
MT29.02.2016
[2018/31]
Former [2018/30]HU27.02.2009
AT03.06.2015
BE03.06.2015
CY03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
MK03.06.2015
MT03.06.2015
NL03.06.2015
PL03.06.2015
RO03.06.2015
SE03.06.2015
SI03.06.2015
SK03.06.2015
TR03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
GB27.02.2016
IE27.02.2016
LU27.02.2016
CH29.02.2016
FR29.02.2016
LI29.02.2016
Former [2018/28]HU27.02.2009
AT03.06.2015
BE03.06.2015
CY03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
MK03.06.2015
MT03.06.2015
NL03.06.2015
PL03.06.2015
RO03.06.2015
SE03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
GB27.02.2016
IE27.02.2016
LU27.02.2016
CH29.02.2016
FR29.02.2016
LI29.02.2016
Former [2017/40]AT03.06.2015
BE03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
MT03.06.2015
NL03.06.2015
PL03.06.2015
RO03.06.2015
SE03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
GB27.02.2016
IE27.02.2016
LU27.02.2016
CH29.02.2016
FR29.02.2016
LI29.02.2016
Former [2017/10]AT03.06.2015
BE03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
GB27.02.2016
IE27.02.2016
LU27.02.2016
CH29.02.2016
FR29.02.2016
LI29.02.2016
Former [2017/08]AT03.06.2015
BE03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
GB27.02.2016
IE27.02.2016
LU27.02.2016
CH29.02.2016
LI29.02.2016
Former [2017/07]AT03.06.2015
BE03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
IE27.02.2016
LU27.02.2016
CH29.02.2016
LI29.02.2016
Former [2017/03]AT03.06.2015
BE03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
LU27.02.2016
CH29.02.2016
LI29.02.2016
Former [2016/46]AT03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
LU27.02.2016
BE29.02.2016
CH29.02.2016
LI29.02.2016
Former [2016/43]AT03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
LU27.02.2016
BE29.02.2016
Former [2016/42]AT03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
MC03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
BE29.02.2016
Former [2016/24]AT03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
PL03.06.2015
RO03.06.2015
SI03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
BE29.02.2016
Former [2016/21]AT03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
IT03.06.2015
LT03.06.2015
LV03.06.2015
PL03.06.2015
RO03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
Former [2016/20]AT03.06.2015
CZ03.06.2015
DK03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
LT03.06.2015
LV03.06.2015
PL03.06.2015
RO03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
Former [2016/10]AT03.06.2015
CZ03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
LT03.06.2015
LV03.06.2015
PL03.06.2015
RO03.06.2015
SK03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
IS03.10.2015
PT06.10.2015
Former [2016/09]AT03.06.2015
EE03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
LT03.06.2015
LV03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
Former [2015/51]AT03.06.2015
ES03.06.2015
FI03.06.2015
HR03.06.2015
LT03.06.2015
LV03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
Former [2015/50]ES03.06.2015
FI03.06.2015
HR03.06.2015
LT03.06.2015
LV03.06.2015
BG03.09.2015
NO03.09.2015
GR04.09.2015
Former [2015/49]ES03.06.2015
FI03.06.2015
HR03.06.2015
LT03.06.2015
LV03.06.2015
NO03.09.2015
GR04.09.2015
Cited inInternational search[I]WO0036092  (BIOGEN INC [US], et al) [I] 1-26,35-40,66-68 * the whole document *;
 [XP]WO2008112325  (BIOGEN IDEC INC [US], et al) [XP] 1-10 * the whole document *;
 [A]  - BROWNING J L ET AL, "Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 1 OCT 1997, (19971001), vol. 159, no. 7, ISSN 0022-1767, pages 3288 - 3298, XP002535405 [A] 1-69
 [A]  - GOMMERMAN JENNIFER L ET AL, "A role for surface lymphotoxin in experimental autoimmune encephalomyelitis independent of LIGHT.", JOURNAL OF CLINICAL INVESTIGATION, (200309), vol. 112, no. 5, ISSN 0021-9738, pages 755 - 767, XP002535406 [A] 1-69

DOI:   http://dx.doi.org/10.1172/jci20318648
 [A]  - DEGLI-ESPOSTI M A ET AL, "Activation of the lymphotoxin beta receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells", JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, (19970215), vol. 158, no. 4, ISSN 0022-1767, pages 1756 - 1762, XP002141941 [A] 1-69
 [A]  - JENNISSEN HERBERT P, "Hydrophobic interaction chromatography: harnessing multivalent protein-surface interactions for purification procedures.", METHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.) 2005, (2005), vol. 305, ISSN 1064-3745, pages 81 - 99, XP008108104 [A] 1-69
Examination   - BROWNING J L ET AL, "SIGNALING THROUGH THE LYMPHOTOXIN BETA RECEPTOR INDUCES THE DEATH OF SOME ADENOCARCINOMA TUMOR LINES", THE JOURNAL OF EXPERIMENTAL MEDICINE, ROCKEFELLER UNIVERSITY PRESS, US, (19960301), vol. 183, no. 3, doi:10.1084/JEM.183.3.867, ISSN 0022-1007, pages 867 - 878, XP000571445

DOI:   http://dx.doi.org/10.1084/jem.183.3.867
by applicant   - STINCHCOMB ET AL., NATURE, (1979), vol. 282, page 39
    - KINGSMAN ET AL., GENE, (1979), vol. 7, page 141
    - TSCHEMPER ET AL., GENE, (1980), vol. 10, page 157
    - JONES, GENETICS, (1977), vol. 85, page 12
    - WHITAKER ET AL., ANN. NEURAL., (1995), vol. 38, no. 4, pages 635 - 632
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.